Neuroimaging in multiple sclerosis.

Abstract:

:Since its clinical introduction in the early 1980s, MRI has transformed the practice of differential diagnosis and disease monitoring for disorders affecting the central nervous system, in particular multiple sclerosis and the allied inflammatory demyelinating diseases. Widespread and dynamic inflammatory processes of the white matter that were largely invisible by CT scanning now are rendered in exquisite detail by conventional MRI, and newer techniques are providing a wealth of information regarding axonal degeneration and functional adaptation. Overuse and over-reliance on MRI by clinicians sometimes can occur, and careful interpretation and clinical judgment remain essential in the care of multiple sclerosis.

journal_name

Neurol Clin

journal_title

Neurologic clinics

authors

Ali EN,Buckle GJ

doi

10.1016/j.ncl.2008.09.012

subject

Has Abstract

pub_date

2009-02-01 00:00:00

pages

203-19, ix

issue

1

eissn

0733-8619

issn

1557-9875

pii

S0733-8619(08)00114-X

journal_volume

27

pub_type

杂志文章,评审
  • Disorders of glycogen metabolism of muscle.

    abstract::Glycogen is a crucial source of energy in the initial stages of muscle activity and during exercise of high intensity. There are 10 well-defined biochemical defects of glycogen metabolism expressed in muscle and affecting the following enzymes: alpha 1,4 glucosidase (glycogenesis type II), debrancher enzyme (III), bra...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:

    authors: Servidei S,DiMauro S

    更新日期:1989-02-01 00:00:00

  • Shift Work Disorder.

    abstract::Shift work and its negative consequences are becoming more relevant as the economy becomes increasing globalized. For many individuals, shift work serves as a significant biological and psychosocial challenge leading to Shift Work Disorder (SWD). Beyond the symptoms of sleep and excessive sleepiness, the range of cons...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ncl.2019.03.003

    authors: Cheng P,Drake C

    更新日期:2019-08-01 00:00:00

  • Headache epidemiology. Emphasis on migraine.

    abstract::Through the use of IHS criteria, large population-based epidemiologic studies in Denmark, the United States, France, Canada, and elsewhere have shed light on the descriptive epidemiology of migraine. Although migraine is a remarkably common cause of temporary disability, many migraineurs, even those with disabling hea...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8619(05)70265-6

    authors: Silberstein SD,Lipton RB

    更新日期:1996-05-01 00:00:00

  • Neurology of Pregnancy: A Case-Oriented Review.

    abstract::The anatomic and physiologic changes that occur during pregnancy are unique. A neurologist needs to be aware of normal pregnancy-induced physiologic changes in the cardiovascular, renal, hematologic, and autoimmune systems, and the local anatomic changes, which include alteration of body habitus and pelvic ligaments. ...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ncl.2016.04.009

    authors: O'Neal MA

    更新日期:2016-08-01 00:00:00

  • Comorbidity of migraine and psychiatric disorders.

    abstract::This article reviews the evidence for comorbidity of migraine with psychiatric disorders, particularly the affective and anxiety disorders. Studies of the association between migraine and depression in both clinical and community studies have provided consistent evidence regarding a substantial degree of comorbidity b...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8619(05)70298-x

    authors: Merikangas KR,Stevens DE

    更新日期:1997-02-01 00:00:00

  • Spine and spinal cord trauma: diagnosis and management.

    abstract::Spine trauma is a devastating clinical condition that affects many people annually on a worldwide basis. Management of spinal trauma has become much more surgically oriented with advances in stabilization techniques over the past two decades. The degree of injury to the spinal cord dictates the prognosis of the patien...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ncl.2012.09.012

    authors: Zhang S,Wadhwa R,Haydel J,Toms J,Johnson K,Guthikonda B

    更新日期:2013-02-01 00:00:00

  • Multifocal motor neuropathy.

    abstract::We believe that our present understanding of these syndromes is insufficient to separate CIDP from MMN clearly and consider MMN to be a remarkably multifocal, predominantly motor variant of CIDP with the very unusual electrophysiologic feature of conduction block confined to motor axons. Further studies are clearly ne...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:

    authors: Parry GJ,Sumner AJ

    更新日期:1992-08-01 00:00:00

  • Neurologic manifestations of gastrointestinal disease.

    abstract::The neurologic manifestations of gastrointestinal disease are generally thought to be uncommon, although an increasing number of previously unidentified associations are being established. These neurologic disorders may result from nutritional or non-nutritional causes. In the absence of clear malnutrition, it is like...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:

    authors: Albers JW,Nostrant TT,Riggs JE

    更新日期:1989-08-01 00:00:00

  • Intravenous thyrotropin-releasing hormone in patients with amyotrophic lateral sclerosis. Dose-response and randomized concurrent placebo-controlled pilot studies.

    abstract::Focal, small-to-moderate and transient improvement occurred in the muscle strength and function of patients with ALS who received TRH in dose-response and screening studies. In a small pilot study of 12 patients, 3 months administration of TRH at 10 mg per kg on alternate days resulted in localized increased strength ...

    journal_title:Neurologic clinics

    pub_type: 临床试验,杂志文章

    doi:

    authors: Brooks BR,Sufit RL,Montgomery GK,Beaulieu DA,Erickson LM

    更新日期:1987-02-01 00:00:00

  • Complications of stereotactic brain surgery.

    abstract::The authors review iatrogenic complications of stereotactic surgery, including tumor biopsy, cyst or abscess aspiration, movement disorder surgery, and radiosurgery. The expected morbidities and steps taken to reduce complications are also discussed. ...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8619(05)70366-2

    authors: Kondziolka D,Firlik AD,Lunsford LD

    更新日期:1998-02-01 00:00:00

  • Neurologic pain syndromes in patients with cancer.

    abstract::Recognizing and treating the cause of pain in the patient with cancer should be the initial approach to the management of this common symptom. Careful analysis of patients with cancer and pain has led to the elucidation of common neurologic pain syndromes unique to this disease process. Pain in patients with cancer is...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:

    authors: Elliott K,Foley KM

    更新日期:1989-05-01 00:00:00

  • Tourette syndrome. Treatment of tics.

    abstract::There are a number of medications that effectively relieve symptoms in patients with functionally disabling tics. Neuroleptic drugs remain the most predictably effective tic-suppressing agents, but other approaches may be beneficial. This article reviews the spectrum of available therapies to suppress tics and provide...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8619(05)70321-2

    authors: Kurlan R

    更新日期:1997-05-01 00:00:00

  • Nerve agents.

    abstract::Nerve agents cause a rapidly fatal cholinergic crisis, but rapid, appropriate antidotal treatment saves lives. Survivors of nerve-agent poisoning generally are healthy, unlike survivors of some other chemical agent attacks. Neurologists can assist first responders and mass casualty planners materially by serving as re...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ncl.2004.12.013

    authors: Newmark J

    更新日期:2005-05-01 00:00:00

  • Tension-type headache.

    abstract::The substantial societal and individual burdens associated with tension-type headache (TTH) constitute a previously overlooked major public health issue. TTH is prevalent, affecting up to 78% of the general population, and 3% suffer from chronic TTH. Pericranial myofascial nociception probably is important for the pat...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ncl.2008.11.010

    authors: Bendtsen L,Jensen R

    更新日期:2009-05-01 00:00:00

  • Neurosurgical management of spasticity, rigidity, and tremor.

    abstract::In this review, the authors present a critical overview of the historical development, indications, complications, operative techniques, and results of procedures for the alleviation of the major dyskinesias. Emphasis is placed upon recent refinement of technique, particularly stereotaxis, as well as neurophysiologic ...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:

    authors: Zager EL

    更新日期:1987-11-01 00:00:00

  • Periodic limb movements and restless legs syndrome.

    abstract::The criteria that characterize restless legs syndrome (RLS) and the differential diagnoses are discussed. Clinical signs include sleep disturbance, involuntary movements in sleep or wakefulness, a normal neurologic examination, a chronic clinical course, and, in some cases, a positive family history. Periodic limb mov...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8619(05)70277-2

    authors: Trenkwalder C,Walters AS,Hening W

    更新日期:1996-08-01 00:00:00

  • Brain death.

    abstract::Current law in the United States authorizes physicians to diagnose brain death by applying generally accepted neurologic criteria for determining loss of function of the entire brain. This article offers a medical-legal perspective on problems that may arise with respect to the determination of brain death. These incl...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8619(05)70132-8

    authors: Beresford HR

    更新日期:1999-05-01 00:00:00

  • Immunotherapy for Alzheimer's disease.

    abstract::The immune system plays a significant role in Alzheimer disease (AD). β-Amyloid deposition in the cortex is thought to be an initiating event in AD and the widely believed amyloid hypothesis proposes removal of amyloid may delay disease progression. Human trials of active or passive immune agents have failed to show b...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ncl.2013.03.012

    authors: Farlow MR,Brosch JR

    更新日期:2013-08-01 00:00:00

  • Neuro-ultrasonography.

    abstract::Transcranial Doppler ultrasonography (TCD) is a noninvasive, bedside, portable tool for assessment of cerebral hemodynamics. Modern TCD head frames allow continuous hands-free emboli detection for risk stratification and assessment of treatment efficacy in several cardiovascular diseases. Identifying a focal stenosis,...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ncl.2019.09.006

    authors: Hakimi R,Alexandrov AV,Garami Z

    更新日期:2020-02-01 00:00:00

  • The use of somatosensory evoked potentials for the evaluation of the peripheral nervous system.

    abstract::Use of the somatosensory evoked potential (SEP) in the evaluation of the peripheral nervous system is described. When using SEPs to evaluate peripheral nervous system disease, it is assumed that the central nervous system is intact. SEPs can be used to measure conduction through nerves that, by nature of their anatomi...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:

    authors: Eisen A

    更新日期:1988-11-01 00:00:00

  • New strategies for endovascular recanalization of acute ischemic stroke.

    abstract::Although intravenous thrombolysis with recombinant tissue plasminogen activator is a proven effective therapy for acute ischemic stroke, it is often insufficient to achieve recanalization in patients with large intracranial artery occlusions. In these cases, intra-arterial reperfusion techniques may be useful. Intra-a...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ncl.2013.03.009

    authors: Cohen JE,Leker RR,Rabinstein A

    更新日期:2013-08-01 00:00:00

  • Practical management of children with apparent learning disabilities.

    abstract::There should be a collaborative evaluation of a child with apparent learning disabilities. This article describes what the neurologist can expect from the other disciplines and how the services can be coordinated, using either the multidisciplinary services of a clinic or comprehensive assessment by a private practiti...

    journal_title:Neurologic clinics

    pub_type: 杂志文章

    doi:

    authors: Schimschock JR,Milford-Cooley M,Cooley N

    更新日期:1984-02-01 00:00:00

  • Therapeutic and Diagnostic Challenges in Myasthenia Gravis.

    abstract::"Myasthenia gravis (MG) is the most common autoimmune neuromuscular disorder. This article highlights several cases that the practicing neurologist may encounter in the treatment of MG. Diagnostic uncertainty continues to be an issue in patients who are seronegative to the 2 most common antibodies, acetylcholine recep...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ncl.2020.03.005

    authors: Nguyen T,Phan CL,Supsupin E Jr,Sheikh K

    更新日期:2020-08-01 00:00:00

  • An Overview of the Current State and the Future of Ataxia Treatments.

    abstract::Cerebellar ataxia can be caused by a variety of disorders, including degenerative processes, autoimmune and paraneoplastic illness as well as by gene mutations inherited in autosomal dominant, autosomal recessive, or X-linked fashions. In this review, we highlight the treatments for cerebellar ataxia in a systematic w...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ncl.2020.01.008

    authors: Kwei KT,Kuo SH

    更新日期:2020-05-01 00:00:00

  • Metabolic and mitochondrial myopathies.

    abstract::Metabolic and mitochondrial myopathies encompass a heterogeneous group of disorders that result in impaired energy production in skeletal muscle. Symptoms of premature muscle fatigue, sometimes leading to myalgia, rhabdomyolysis, and myoglobinuria, typically occur with exercise that would normally depend on the defect...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ncl.2014.05.001

    authors: Sharp LJ,Haller RG

    更新日期:2014-08-01 00:00:00

  • History of sleep medicine.

    abstract::Sleeping and dreaming always have been a fundamental part of human existence. Most early writing on these subjects was almost entirely speculation. During the twentieth century, however, scientific observation and experimentation abounded. This article emphasizes the evolution of the key concepts and research findings...

    journal_title:Neurologic clinics

    pub_type: 历史文章,杂志文章

    doi:10.1016/j.ncl.2005.07.001

    authors: Dement WC

    更新日期:2005-11-01 00:00:00

  • Developmental considerations of neurotoxic exposures.

    abstract::In this article, the authors provide a conceptual framework in which to consider alternative approaches to identify the developmental consequences of exposing the developing brain to neurotoxic substances. Concepts underlying brain development and issues regarding neurobehavioral testing in children are reviewed. In a...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8619(05)70210-3

    authors: Trask CL,Kosofsky BE

    更新日期:2000-08-01 00:00:00

  • Advances and Future Directions of Neuromodulation in Neurologic Disorders.

    abstract::"Deep brain stimulation is a safe and effective therapy for the management of a variety of neurologic conditions with Food and Drug Administration or humanitarian exception approval for Parkinson disease, dystonia, tremor, and obsessive-compulsive disorder. Advances in neurophysiology, neuroimaging, and technology hav...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ncl.2020.09.004

    authors: Burns MR,Chiu SY,Patel B,Mitropanopoulos SG,Wong JK,Ramirez-Zamora A

    更新日期:2021-02-01 00:00:00

  • The neck and headaches.

    abstract::Cervicogenic headache is pain referred to the head from a source in the cervical spine or mediated by cervical nerves. Clinical features allow for no more than a diagnosis of probable cervicogenic headache. Definitive diagnosis requires evidence of a cervical source of pain. For most treatments, the evidence is limite...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ncl.2013.11.005

    authors: Bogduk N

    更新日期:2014-05-01 00:00:00

  • Neurophysiologic monitoring in the neuroscience intensive care unit.

    abstract::Neurologically critically ill patients, more often than others, are unable to communicate and, for a crucial period of time, have the vital functions of their brains hidden in the "black box" of the cranial vault behind a curtain of ambiguity and immobility. Customarily--and naively--we have relied upon beside clinica...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:

    authors: Jordan KG

    更新日期:1995-08-01 00:00:00