Advances and Future Directions of Neuromodulation in Neurologic Disorders.

abstract：:Neurologists frequently evaluate patients complaining of vision loss, especially when the patient has been examined by an ophthalmologist who has found no ocular disease. A significant proportion of patients presenting to the neurologist with visual complaints have nonorganic or functional visual loss. Although there ...

journal_title：Neurologic clinics

authors： Bruce BB,Newman NJ

更新日期：2010-08-01 00:00:00

abstract：:Oxidative phosphorylation (OXPHOS) accounts for approximately 95% of the adenosine triphosphate (ATP) produced by the cell. The central nervous system, peripheral nervous system, cardiac muscle, skeletal muscle, and smooth muscle are highly susceptible to dysfunction of this complex enzyme system. Although most OXPHOS...

journal_title：Neurologic clinics

authors： Shoffner JM

更新日期：2000-02-01 00:00:00

abstract：:Channelopathies, neuromuscular junction disorders, and myopathies represent multiple mechanisms by which toxins can affect the peripheral nervous system. These toxins include ciguatoxin, tetrodotoxin, botulinum toxin, metabolic poisons, venomous snake bites, and several medications. These toxins are important to be aw...

journal_title：Neurologic clinics

authors： Janecek J,Kushlaf H

更新日期：2020-11-01 00:00:00

abstract：:Idiopathic intracranial hypertension is a syndrome of increased intracranial pressure of unknown cause that most often occurs in women of childbearing age. Most patients are overweight or obese with a history of recent weight gain. Following a brief review of the symptoms and signs, we discuss the approach to assessme...

journal_title：Neurologic clinics

authors： Thurtell MJ,Kawasaki A

更新日期：2021-02-01 00:00:00

abstract：:Amyotrophic lateral sclerosis can be described as a disease with a poorly understood pathophysiologic mechanism and no treatment that dramatically impacts the course of the disease. Clinical trialists are faced with finding small treatment effects against a background of multiple potential treatments, a past history o...

journal_title：Neurologic clinics

authors： Katz JS,Barohn RJ,Dimachkie MM,Mitsumoto H

更新日期：2015-11-01 00:00:00

abstract：:Dementia, defined as progressive cognitive decline, is a feature of a wide variety of genetic disorders. For example, a search of "dementia" in the Online Mendelian Inheritance in Man (www.ncbi.nlm.nih.gov/Omim) reveals 162 entries. Therefore this article cannot be encyclopedic and will be necessarily restricted to mo...

journal_title：Neurologic clinics

authors： Hedera P,Turner RS

更新日期：2002-08-01 00:00:00

abstract：:Tuberous sclerosis is a multisystem disorder characterized by changes primarily involving the skin, eye, and central nervous system. Although the disease often produces mental retardation and seizures, this is not universal, and some patients with tuberous sclerosis lead a relatively normal life. ...

journal_title：Neurologic clinics

authors： Hanno R,Beck R

更新日期：1987-08-01 00:00:00

abstract：:Drug-induced seizures are a commonly encountered problem for physicians. In this article, drugs that cause seizures are discussed with regards to the incidence of seizures, associated clinical factors, risk factors, and special treatment considerations. This information should help physicians determine appropriate eva...

journal_title：Neurologic clinics

authors： Garcia PA,Alldredge BK

更新日期：1994-02-01 00:00:00

abstract：:Toxic myopathies may occur with a variety of prescribed medications, illicit drug abuse, or other toxins. The article discusses an overview of some of the compounds that may cause myopathy, the clinical and laboratory features, histology, mechanisms of action, and potential risk factors of myopathy. The ability to rec...

journal_title：Neurologic clinics

authors： George KK,Pourmand R

更新日期：1997-08-01 00:00:00

abstract：:Transcranial Doppler ultrasonography (TCD) is a noninvasive, bedside, portable tool for assessment of cerebral hemodynamics. Modern TCD head frames allow continuous hands-free emboli detection for risk stratification and assessment of treatment efficacy in several cardiovascular diseases. Identifying a focal stenosis,...

journal_title：Neurologic clinics

authors： Hakimi R,Alexandrov AV,Garami Z

更新日期：2020-02-01 00:00:00

abstract：:The past 40 years have seen the evolution of acute ischemic stroke management from unproven therapies du jour, such as steroids, heparin for stroke in evolution, and hypervolemic-hemodilution, to more of a scientific basis for our decision-making process. This evolution is directly related to the advancements in imagi...

journal_title：Neurologic clinics

authors： Kelley RE,Martin-Schild S

更新日期：2012-02-01 00:00:00

abstract：:In this series of clinical vignettes, the authors have attempted to provide a "feel" for the varied causes of syncope. The neurologist should be able to diagnose most causes of syncope using a simple algorithmic approach. Initial evaluation includes detailed clinical history, physical examination, and 12-lead ECG. Fol...

journal_title：Neurologic clinics

authors： Schondorf R,Shen WK

更新日期：2006-05-01 00:00:00

abstract：:Giant cell arteritis is a systemic vasculitis with a wide clinical spectrum, and it represents a medical emergency. Visual loss is the most feared complication, and when it happens, it tends to be profound and permanent. Prompt diagnosis and treatment are imperative to minimize potentially devastating visual loss and ...

journal_title：Neurologic clinics

authors： Falardeau J

更新日期：2010-08-01 00:00:00

abstract：:Shift work and its negative consequences are becoming more relevant as the economy becomes increasing globalized. For many individuals, shift work serves as a significant biological and psychosocial challenge leading to Shift Work Disorder (SWD). Beyond the symptoms of sleep and excessive sleepiness, the range of cons...

journal_title：Neurologic clinics

authors： Cheng P,Drake C

更新日期：2019-08-01 00:00:00

abstract：:Eclampsia continues to be a significant cause of maternal and fetal death throughout the world. Neurologists have a specific role to play in the diagnosis and management of patients who have eclampsia, especially those who have recurrent seizures, raised intracranial pressure, and coma. Postpartum patients may be admi...

journal_title：Neurologic clinics

authors： Kaplan PW

更新日期：2004-11-01 00:00:00

abstract：:Recognizing and treating the cause of pain in the patient with cancer should be the initial approach to the management of this common symptom. Careful analysis of patients with cancer and pain has led to the elucidation of common neurologic pain syndromes unique to this disease process. Pain in patients with cancer is...

journal_title：Neurologic clinics

authors： Elliott K,Foley KM

更新日期：1989-05-01 00:00:00

abstract：:In the current era of escalating globalization with rapid transport, changing climate, and an ever growing human population with associated changes in lifestyle, poverty, and war, the emergence of new neurologic infections is accelerated. Understanding their origins using epidemiologic and molecular tools will contrib...

journal_title：Neurologic clinics

authors： Johnson RT,Power C

更新日期：2008-08-01 00:00:00

abstract：:Guidelines and quality measures for epilepsy care have the potential to improve the quality of epilepsy care. Quality measures are increasingly used for pay-for-performance. This article describes different guidelines and quality measures that have been used to identify best practices, types of best practices for use ...

journal_title：Neurologic clinics

authors： Pugh MJ,McMillan KK

更新日期：2016-05-01 00:00:00

abstract：:Traumatic injury to the posterior fossa is a complex pathologic condition because of the great heterogeneity of lesions present. Treatment of primary brain injuries and prevention of secondary brain injuries is the mainstay of management. It is imperative to recognize traumatic lesions of the posterior fossa early bec...

journal_title：Neurologic clinics

authors： Nixon M,Ambekar S,Zhang S,Markham C,Akbarian-Tefaghi H,Morrow K,Nanda A,Guthikonda B

更新日期：2014-11-01 00:00:00

abstract：:Primary angiitis of the central nervous system (PACNS) is a vasculitis of small arteries and veins of unknown cause restricted to the central nervous system (CNS), and controversy and disagreement exist over the means to establish the diagnosis. Cerebral arteriography, cerebrospinal fluid examination, and MRI singly o...

journal_title：Neurologic clinics

authors： Powers WJ

更新日期：2015-05-01 00:00:00

abstract：:Viruses are a frequent cause of encephalitis. Common or important viruses causing encephalitis include herpesviruses, arboviruses, enteroviruses, parechoviruses, mumps, measles, rabies, Ebola, lymphocytic choriomeningitis virus, and henipaviruses. Other viruses may cause an encephalopathy. Host factors and clinical fe...

journal_title：Neurologic clinics

authors： Venkatesan A,Murphy OC

更新日期：2018-11-01 00:00:00

abstract：:Nerve agents cause a rapidly fatal cholinergic crisis, but rapid, appropriate antidotal treatment saves lives. Survivors of nerve-agent poisoning generally are healthy, unlike survivors of some other chemical agent attacks. Neurologists can assist first responders and mass casualty planners materially by serving as re...

journal_title：Neurologic clinics

authors： Newmark J

更新日期：2005-05-01 00:00:00

abstract：:There is no single definition of pharmacoresistant (intractable, refractory) epilepsy. Prospective identification of pharmacoresistance is complicated by the variability of its appearance across different types of epilepsy and the variability of seizure control within a given patient over time. Failure of informative ...

journal_title：Neurologic clinics

authors： Berg AT

更新日期：2009-11-01 00:00:00

abstract：:This article concentrates primarily on infections of viral origin, although numerous microorganisms can infect the fetal and newborn brain (see Tables 1 and 2). Intrauterine infections occur most often for HIV, CMV and rubella, whereas HSV is preferentially transmitted intrapartum. In the last decade, changes in the e...

journal_title：Neurologic clinics

authors： Griffith BP,Booss J

更新日期：1994-08-01 00:00:00

abstract：:Addressed are the features of postviral and postvaccinial syndromes affecting the CNS. The relationships among acute disseminated encephalomyelitis, EAE, and MS are discussed. Among the postvaccination syndromes covered are the neurologic sequelae of pertussis immunizations, with a description of a mouse model of this...

journal_title：Neurologic clinics

authors： Sriram S,Steinman L

更新日期：1984-05-01 00:00:00

abstract：:The autosomal dominant spinocerebellar ataxias are a diverse and clinically heterogeneous group of disorders characterized by degeneration and dysfunction of the cerebellum and its associated pathways. Clinical and diagnostic evaluation can be challenging because of phenotypic overlap among causes, and a stratified an...

journal_title：Neurologic clinics

authors： Shakkottai VG,Fogel BL

更新日期：2013-11-01 00:00:00

abstract：:Epilepsy surgery is assuming greater importance in treating patients with partial epilepsy whose seizures are uncontrolled with antiepileptic drugs. Many good candidates for surgical treatment are not presented with the option of surgery. The evaluation for epilepsy surgery is extensive and includes several stages of ...

journal_title：Neurologic clinics

authors： Devinsky O,Pacia S

更新日期：1993-11-01 00:00:00

abstract：:Unresponsive patients with or without catatonic motor signs are etiologically heterogeneous, and all require a comprehensive neurodiagnostic assessment to rule out organic causes. Most cases prove to be due to primary psychiatric disorders, mostly mood disorders, especially mania, rather than schizophrenia. These pati...

journal_title：Neurologic clinics

authors： Hurwitz TA

更新日期：2011-11-01 00:00:00

abstract：:Echocardiography is an established technology encompassing an increasingly wide variety of clinical situations including cardioembolism and the detection of CAD in patients with cerebral ischemia and in patients undergoing neurovascular surgery. Echocardiography will continue to occupy a pivotal role in clinical manag...

journal_title：Neurologic clinics

authors： Tegeler CH,Kitzman DW

更新日期：1993-05-01 00:00:00

abstract：:Postamputation phenomena, including painful and nonpainful phantom sensations occur following loss of limbs and other body parts. Peripheral and central nervous system mechanisms play a role in persistent phantom pain. Understanding the pathophysiology of this syndrome has improved in recent years. Comprehensive evalu...

journal_title：Neurologic clinics

authors： Weinstein SM

更新日期：1998-11-01 00:00:00