Drug-induced seizures.

abstract：:Given the magnitude of the problem of motor fluctuations in patients who have Parkinson's disease treated with levodopa, a significant effort has been expended by physicians, researchers, and pharmaceutical manufacturers over the years to find effective treatments. This article briefly reviews the medical options for ...

journal_title：Neurologic clinics

authors： Dewey RB Jr

更新日期：2008-08-01 00:00:00

abstract：:Botulinum toxin therapy has emerged as a treatment modality for a variety of spastic- or contracture-related muscle diseases. Its safety has been proven for long-term use in the treatment of benign essential blepharospasm, hemifacial spasm, and certain types of strabismus. Recent approval from the Federal Drug Adminis...

journal_title：Neurologic clinics

authors： Savino PJ,Maus M

更新日期：1991-02-01 00:00:00

abstract：:Neurologically critically ill patients, more often than others, are unable to communicate and, for a crucial period of time, have the vital functions of their brains hidden in the "black box" of the cranial vault behind a curtain of ambiguity and immobility. Customarily--and naively--we have relied upon beside clinica...

journal_title：Neurologic clinics

authors： Jordan KG

更新日期：1995-08-01 00:00:00

abstract：:Mortality and morbidity from kidney disease and the spectrum of renal-associated neurologic disease have changed markedly since the introduction of renal dialysis and with the advent of renal transplantation. This article includes historical studies of the neurologic complications of acute uremia, now fairly uncommon,...

journal_title：Neurologic clinics

authors： Palmer CA

更新日期：2002-02-01 00:00:00

abstract：:Use of the somatosensory evoked potential (SEP) in the evaluation of the peripheral nervous system is described. When using SEPs to evaluate peripheral nervous system disease, it is assumed that the central nervous system is intact. SEPs can be used to measure conduction through nerves that, by nature of their anatomi...

journal_title：Neurologic clinics

authors： Eisen A

更新日期：1988-11-01 00:00:00

abstract：:Reye syndrome has emerged as the quintessential example of an acute metabolic encephalopathy. The clinical presentation is quite stereotyped in most instances permitting rapid, accurate diagnosis and early therapeutic intervention. Intoxications and certain inborn metabolic errors may mimic Reye syndrome. All patients...

journal_title：Neurologic clinics

authors： De Vivo DC

更新日期：1985-02-01 00:00:00

abstract：:Antidepressants are the most commonly prescribed class of medications in the United States. The clinician should be mindful of the many antidepressants that can produce seizures following an accidental exposure or an overdose. A broader understanding of the seizure potential of antidepressants, combined with the abili...

journal_title：Neurologic clinics

authors： Judge BS,Rentmeester LL

更新日期：2011-08-01 00:00:00

abstract：:The nervous system is involved in approximately 25% of patients with classical Wegener's granulomatosis. The spectrum of this disease has been broadened with the discovery of the anti-neutrophil cytoplasmic antibodies, which are found in diseases sharing many clinical features. The ANCA testing may indicate a common m...

journal_title：Neurologic clinics

authors： Jaffe IA

更新日期：1997-11-01 00:00:00

abstract：:Animal and human research has clearly shown that anticonvulsants are teratogens and pose a risk for fetal malformations. In the case of dilantin it appears that fetal susceptibility correlates with the fetal level of the microsomal detoxifying enzyme epoxide hydrolase. The genetics of seizures in the parents does not ...

journal_title：Neurologic clinics

authors： Buehler BA,Rao V,Finnell RH

更新日期：1994-11-01 00:00:00

abstract：:Psychogenic movement disorders (PMDs) can present with varied phenomenology that may resemble organic movement disorders. The diagnosis is based on clinical evaluation with a supporting history and classic features on neurologic examination. Ancillary testing, such as imaging and neurophysiologic studies, can provide ...

journal_title：Neurologic clinics

authors： Thenganatt MA,Jankovic J

更新日期：2015-02-01 00:00:00

abstract：:Childhood sleep-wake disorders are common and associated with significant impairment of quality of life. The recent discovery of hypocretin deficiency as the pathophysiologic basis for narcolepsy-cataplexy is likely to spur the development of hypocretin analogs for definitive treatment [82,83]. The link between disrup...

journal_title：Neurologic clinics

authors： Kotagal S

更新日期：2003-11-01 00:00:00

abstract：:Since its clinical introduction in the early 1980s, MRI has transformed the practice of differential diagnosis and disease monitoring for disorders affecting the central nervous system, in particular multiple sclerosis and the allied inflammatory demyelinating diseases. Widespread and dynamic inflammatory processes of...

journal_title：Neurologic clinics

authors： Ali EN,Buckle GJ

更新日期：2009-02-01 00:00:00

abstract：:The three states of mammalian being--wakefulness, REM sleep, and NREM sleep--are not mutually exclusive and may occur simultaneously, oscillate rapidly, or appear in dissociated or incomplete form to produce primary sleep parasomnias. Dysfunctions of a wide variety of organ systems may take advantage of the sleeping s...

journal_title：Neurologic clinics

authors： Mahowald MW,Schenck CH

更新日期：1996-11-01 00:00:00

abstract：:Considerable evidence exists of hypothalamic dysfunction in patients with anorexia nervosa and bulimia nervosa. This dysfunction is reflected in disturbances of endocrine function including abnormalities of gonadotropin, growth hormone, and corticotropin-releasing hormone secretion. Whereas these disturbances are gene...

journal_title：Neurologic clinics

authors： Newman MM,Halmi KA

更新日期：1988-02-01 00:00:00

abstract：:The nature, prevalence, and course of cognitive and emotional disturbances in multiple sclerosis (MS) are described in this article. Mild to moderate cognitive impairment is common in MS and may be more incapacitating than physical symptoms for some patients. Although existing neurologic and neuroimaging procedures ca...

journal_title：Neurologic clinics

authors： Beatty WW

更新日期：1993-02-01 00:00:00

abstract：:Echocardiography is an established technology encompassing an increasingly wide variety of clinical situations including cardioembolism and the detection of CAD in patients with cerebral ischemia and in patients undergoing neurovascular surgery. Echocardiography will continue to occupy a pivotal role in clinical manag...

journal_title：Neurologic clinics

authors： Tegeler CH,Kitzman DW

更新日期：1993-05-01 00:00:00

abstract：:Oxidative phosphorylation (OXPHOS) accounts for approximately 95% of the adenosine triphosphate (ATP) produced by the cell. The central nervous system, peripheral nervous system, cardiac muscle, skeletal muscle, and smooth muscle are highly susceptible to dysfunction of this complex enzyme system. Although most OXPHOS...

journal_title：Neurologic clinics

authors： Shoffner JM

更新日期：2000-02-01 00:00:00

abstract：:The last 2 decades represent a period of unparalleled advancement in the understanding of the pathogenesis of Parkinson disease (PD). The discovery of several forms of familial parkinsonism with mendelian inheritance has elucidated insights into the mechanisms underlying the degeneration of dopaminergic neurons of the...

journal_title：Neurologic clinics

authors： Mullin S,Schapira AH

更新日期：2015-02-01 00:00:00

abstract：:Infantile spasms are a seizure disorder in young infants with diverse etiologies, suggesting that they arise from any disturbance of central nervous system function during susceptible periods of development. The prognosis for normal intellectual and neurologic development parallels that of the underlying etiology. Ear...

journal_title：Neurologic clinics

authors： Bobele GB,Bodensteiner JB

更新日期：1990-08-01 00:00:00

abstract：:Idiopathic intracranial hypertension is a syndrome of increased intracranial pressure of unknown cause that most often occurs in women of childbearing age. Most patients are overweight or obese with a history of recent weight gain. Following a brief review of the symptoms and signs, we discuss the approach to assessme...

journal_title：Neurologic clinics

authors： Thurtell MJ,Kawasaki A

更新日期：2021-02-01 00:00:00

abstract：:The use of IH for 24 hours in patients who remain comatose following resuscitation from out-of-hospital cardiac arrest improves outcomes. How-ever, the induction of hypothermia has several physiologic effects that need to be considered. A protocol for the rapid induction of hypothermia is described. At present, the ra...

journal_title：Neurologic clinics

authors： Bernard S

更新日期：2006-02-01 00:00:00

abstract：:Nonsurgical, conservative approaches to spine pain include medication and physical therapy. In addition, several invasive procedures have been developed to provide relief when conservative options fail. These include facet joint injection and radiofrequency ablation techniques, translaminar and transforaminal epidural...

journal_title：Neurologic clinics

authors： Levin KH

更新日期：2007-05-01 00:00:00

abstract：:This article provides a brief overview of the psychiatric syndromes most common in the elderly patient, as well as those most frequently accompanying neurologic disease. Diagnosis, work up, and treatment of depressive, psychotic, and anxiety disorders are also reviewed. This article is directed toward the practicing n...

journal_title：Neurologic clinics

authors： Menza MA,Liberatore BL

更新日期：1998-08-01 00:00:00

abstract：:The immune system plays a significant role in Alzheimer disease (AD). β-Amyloid deposition in the cortex is thought to be an initiating event in AD and the widely believed amyloid hypothesis proposes removal of amyloid may delay disease progression. Human trials of active or passive immune agents have failed to show b...

journal_title：Neurologic clinics

authors： Farlow MR,Brosch JR

更新日期：2013-08-01 00:00:00

abstract：:As I have indicated in the foregoing discussion, there are several syndromes that with various degrees of proof seem to be caused by unilateral vascular compression of a cranial nerve at the brain stem. Jannetta has summarized this concept as follows: "As we age, our arteries elongate and our brains 'sag'. As a conseq...

journal_title：Neurologic clinics

authors： Wilkins RH

更新日期：1985-05-01 00:00:00

abstract：:Recognizing and treating the cause of pain in the patient with cancer should be the initial approach to the management of this common symptom. Careful analysis of patients with cancer and pain has led to the elucidation of common neurologic pain syndromes unique to this disease process. Pain in patients with cancer is...

journal_title：Neurologic clinics

authors： Elliott K,Foley KM

更新日期：1989-05-01 00:00:00

abstract：:Many substances, organic and manufactured, may induce peripheral nerve damage when exposed to them. The expected clinical phenotype is of a distal, sensory or sensorimotor polyneuropathy, often painful, with axonal characteristics on electrodiagnostic and histopathologic analysis. Treatment is limited; often, the only...

journal_title：Neurologic clinics

authors： Grogan PM,Katz JS

更新日期：2005-05-01 00:00:00

abstract：:Supratentorial low-grade gliomas comprise a group of primary central nervous system neoplasms with characteristics of neuroglial cells (i.e., astrocytes and oligodendrocytes) and relatively low anaplastic potential, although through time they tend to behave more aggressively. Immediate surgical intervention and subseq...

journal_title：Neurologic clinics

authors： Recht LD,Bernstein M

更新日期：1995-11-01 00:00:00

abstract：:The authors highlight the potential importance of neuropeptides as clinical tools in the study and treatment of pain. Although many questions remain unanswered, it is encouraging that several clinical and experimental advances have shed new light on the neuropharmacology of nociception and have prompted new hope for m...

journal_title：Neurologic clinics

authors： Recht LD,Abrams GM

更新日期：1986-11-01 00:00:00

abstract：:The evaluation and treatment of spinal cord injury continues to evolve, enhanced by new imaging modalities. Their application in reference to the cervical, thoracic, and lumbar spine is discussed. Treatment options, both conservative and surgical, are outlined. ...

journal_title：Neurologic clinics

authors： Meyer PR Jr,Cybulski GR,Rusin JJ,Haak MH

更新日期：1991-08-01 00:00:00