Metabolic and mitochondrial myopathies.

Abstract:

:Metabolic and mitochondrial myopathies encompass a heterogeneous group of disorders that result in impaired energy production in skeletal muscle. Symptoms of premature muscle fatigue, sometimes leading to myalgia, rhabdomyolysis, and myoglobinuria, typically occur with exercise that would normally depend on the defective metabolic pathway. But in another group of these disorders, the dominant muscle symptom is weakness. This article reviews the clinical features, diagnosis, and management of these diseases with emphasis on the recent literature.

journal_name

Neurol Clin

journal_title

Neurologic clinics

authors

Sharp LJ,Haller RG

doi

10.1016/j.ncl.2014.05.001

subject

Has Abstract

pub_date

2014-08-01 00:00:00

pages

777-99, ix

issue

3

eissn

0733-8619

issn

1557-9875

pii

S0733-8619(14)00035-8

journal_volume

32

pub_type

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