Acquired peripheral neuropathy.

abstract：:Many abnormalities of the orbit present with neuro-ophthalmic findings, such as impaired ocular motility or alignment, and sensory changes, including optic neuropathy. Comprehensive coverage of all orbital diseases is beyond the scope of this article. This review focuses on diagnosis and management of the most common ...

journal_title：Neurologic clinics

authors： Chang JR,Gruener AM,McCulley TJ

更新日期：2017-02-01 00:00:00

abstract：:Normal cell replication is regulated by growth factors such as epidermal growth factor (EGF) and platelet-derived growth factor (PDGF) that act through binding to specific surface receptors on target cells. Oncogenes may exert their transforming activity by encoding proteins that mimic the function of the normal regul...

journal_title：Neurologic clinics

authors： Westermark B,Nister M,Heldin CH

更新日期：1985-11-01 00:00:00

abstract：:"Deep brain stimulation is a safe and effective therapy for the management of a variety of neurologic conditions with Food and Drug Administration or humanitarian exception approval for Parkinson disease, dystonia, tremor, and obsessive-compulsive disorder. Advances in neurophysiology, neuroimaging, and technology hav...

journal_title：Neurologic clinics

authors： Burns MR,Chiu SY,Patel B,Mitropanopoulos SG,Wong JK,Ramirez-Zamora A

更新日期：2021-02-01 00:00:00

abstract：:Traumatic brain injury is a common and complex clinical entity that deserves better and continued research on interventions and initial treatment postinjury. Current medical management of traumatic brain injury is articulated on minimizing secondary injury by optimizing cerebral perfusion and oxygenation and preventin...

journal_title：Neurologic clinics

authors： Ling GS,Marshall SA

更新日期：2008-05-01 00:00:00

abstract：:Face recognition is one of the most complex visual tasks performed by the human brain. Data from monkeys suggest that area IT may play a key role in identifying faces, and functional imaging research suggests that the human homologue of IT may be located in the medial occipitotemporal cortex, where a FFA has been loca...

journal_title：Neurologic clinics

authors： Barton JJ

更新日期：2003-05-01 00:00:00

abstract：:In this article, the authors provide a conceptual framework in which to consider alternative approaches to identify the developmental consequences of exposing the developing brain to neurotoxic substances. Concepts underlying brain development and issues regarding neurobehavioral testing in children are reviewed. In a...

journal_title：Neurologic clinics

authors： Trask CL,Kosofsky BE

更新日期：2000-08-01 00:00:00

abstract：:Psychiatric disorders occurring in patients with epilepsy are complications, not an essential part of the illness, and may be prevented or ameliorated. Outlined are risk factors and medical treatment and the need for education concerning epilepsy and for encouragement of the patient by the physician. ...

journal_title：Neurologic clinics

authors： Green JB,Mercille RA

更新日期：1984-02-01 00:00:00

abstract：:Paraproteinemia frequently is associated with peripheral neuropathy. The clinical manifestations can be protean owing to the potential for multiple organ involvement. A methodical diagnostic approach to patients who have a plasma cell dyscrasia and neuropathy is necessary to ensure the appropriate detection of more wi...

journal_title：Neurologic clinics

authors： Kwan JY

更新日期：2007-02-01 00:00:00

abstract：:As in most areas of clinical medicine, the history often is the key to determining the diagnosis in patients presenting with neurotologic symptoms. The most common cause of vertigo--benign positional vertigo--can be diagnosed at the bedside based on the characteristic history and the finding of fatigable positional ny...

journal_title：Neurologic clinics

authors： Baloh RW,Jacobson KM

更新日期：1996-02-01 00:00:00

abstract：:This article discusses antibodies associated with immune-mediated myasthenia gravis and the pathologic action of these antibodies at the neuromuscular junctions of skeletal muscle. To explain how these antibodies act, we consider the physiology of neuromuscular transmission with emphasis on 4 features: the structure o...

journal_title：Neurologic clinics

authors： Ruff RL,Lisak RP

更新日期：2018-05-01 00:00:00

abstract：:"Myasthenia gravis (MG) is the most common autoimmune neuromuscular disorder. This article highlights several cases that the practicing neurologist may encounter in the treatment of MG. Diagnostic uncertainty continues to be an issue in patients who are seronegative to the 2 most common antibodies, acetylcholine recep...

journal_title：Neurologic clinics

authors： Nguyen T,Phan CL,Supsupin E Jr,Sheikh K

更新日期：2020-08-01 00:00:00

abstract：:The clinician should be alert to the possibility of cerebrovascular disease in cancer patients who develop signs of diffuse or focal cerebral dysfunction. The cause of cerebrovascular disease can usually be determined by knowing the primary tumor type, extent of metastatic disease, and type of antineoplastic treatment...

journal_title：Neurologic clinics

authors： Rogers LR

更新日期：1991-11-01 00:00:00

abstract：:The fourth edition of The Diagnostic and Statistical Manual of Mental Disorders defines delirium as "a reversible state of confusion with a reduced level of consciousness manifest as an inability to focus, sustain or shift attention." Pharmacologic agents are important contributors to delirium in hospitalized elderly ...

journal_title：Neurologic clinics

authors： Hanson MR,Gálvez-Jiménez N

更新日期：2004-05-01 00:00:00

abstract：:In this series of clinical vignettes, the authors have attempted to provide a "feel" for the varied causes of syncope. The neurologist should be able to diagnose most causes of syncope using a simple algorithmic approach. Initial evaluation includes detailed clinical history, physical examination, and 12-lead ECG. Fol...

journal_title：Neurologic clinics

authors： Schondorf R,Shen WK

更新日期：2006-05-01 00:00:00

abstract：:Epilepsy affects over one percent of the population, including nearly one million women of childbearing potential. Women with epilepsy represent a particularly challenging group for neurologists and other health care professionals. Affected women are unaware of many of the unique issues they face, including the relati...

journal_title：Neurologic clinics

authors： Foldvary N

更新日期：2001-05-01 00:00:00

abstract：:Addressed are the features of postviral and postvaccinial syndromes affecting the CNS. The relationships among acute disseminated encephalomyelitis, EAE, and MS are discussed. Among the postvaccination syndromes covered are the neurologic sequelae of pertussis immunizations, with a description of a mouse model of this...

journal_title：Neurologic clinics

authors： Sriram S,Steinman L

更新日期：1984-05-01 00:00:00

abstract：:Conventional disease-modifying agents are only moderately effective, so breakthrough disease activity is commonly seen. The evidence from randomized clinical trials and real-world observational data supporting the use of the second-line agents natalizumab, mitoxantrone, and cyclophosphamide are reviewed. Potential fut...

journal_title：Neurologic clinics

authors： Marriott JJ,O'Connor PW

更新日期：2011-05-01 00:00:00

abstract：:Dementia, defined as progressive cognitive decline, is a feature of a wide variety of genetic disorders. For example, a search of "dementia" in the Online Mendelian Inheritance in Man (www.ncbi.nlm.nih.gov/Omim) reveals 162 entries. Therefore this article cannot be encyclopedic and will be necessarily restricted to mo...

journal_title：Neurologic clinics

authors： Hedera P,Turner RS

更新日期：2002-08-01 00:00:00

abstract：:Most patients who have endured a stroke sustain behavioral changes, although in many instances these effects can be subtle. Although behavioral changes after a stroke tend to improve, they may persist and have serious effects on daily living activities. This article reviews the more familiar behavioral changes that fo...

journal_title：Neurologic clinics

authors： Mark VW

更新日期：2016-02-01 00:00:00

abstract：:Transcranial Doppler ultrasonography (TCD) is a noninvasive, bedside, portable tool for assessment of cerebral hemodynamics. Modern TCD head frames allow continuous hands-free emboli detection for risk stratification and assessment of treatment efficacy in several cardiovascular diseases. Identifying a focal stenosis,...

journal_title：Neurologic clinics

authors： Hakimi R,Alexandrov AV,Garami Z

更新日期：2020-02-01 00:00:00

abstract：:SEPs may be recorded over the spine and scalp to stimulation of any accessible mixed or sensory nerve in the extremities. SEP abnormalities are useful in detecting lesions in central somatosensory pathways. They do not establish a specific diagnosis, but they may suggest or support a diagnosis made on clinical grounds...

journal_title：Neurologic clinics

authors： Aminoff MJ

更新日期：1988-11-01 00:00:00

abstract：:Disorders of the autonomic and small nerve fibers comprise a wide spectrum of disease states that cross a multitude of clinical specialties.The evaluation of these disorders allows the investigator to determine the presence or absence of abnormalities in the lightly myelinated and unmyelinated nerve fibers with minima...

journal_title：Neurologic clinics

authors： Gibbons C,Freeman R

更新日期：2004-08-01 00:00:00

abstract：:Toxic myopathies may occur with a variety of prescribed medications, illicit drug abuse, or other toxins. The article discusses an overview of some of the compounds that may cause myopathy, the clinical and laboratory features, histology, mechanisms of action, and potential risk factors of myopathy. The ability to rec...

journal_title：Neurologic clinics

authors： George KK,Pourmand R

更新日期：1997-08-01 00:00:00

abstract：:Echocardiography is an established technology encompassing an increasingly wide variety of clinical situations including cardioembolism and the detection of CAD in patients with cerebral ischemia and in patients undergoing neurovascular surgery. Echocardiography will continue to occupy a pivotal role in clinical manag...

journal_title：Neurologic clinics

authors： Tegeler CH,Kitzman DW

更新日期：1993-05-01 00:00:00

abstract：:Different types of conduction defects, avenues available for functional recovery after demyelination, therapeutic and diagnostic measures, and electrophysiologic testing are covered. ...

journal_title：Neurologic clinics

authors： Eisen A

更新日期：1983-08-01 00:00:00

abstract：:Meaningful symptom management can have a profound impact on quality of life. It can challenge time parameters during clinic, and therefore thought should be given to strategies that can improve efficiency and thereby make the undertaking more tenable. For any given symptom, the building blocks of care, such as vitamin...

journal_title：Neurologic clinics

authors： Crabtree-Hartman E

更新日期：2018-02-01 00:00:00

abstract：:Animal and human research has clearly shown that anticonvulsants are teratogens and pose a risk for fetal malformations. In the case of dilantin it appears that fetal susceptibility correlates with the fetal level of the microsomal detoxifying enzyme epoxide hydrolase. The genetics of seizures in the parents does not ...

journal_title：Neurologic clinics

authors： Buehler BA,Rao V,Finnell RH

更新日期：1994-11-01 00:00:00

abstract：:The neurologic manifestations of gastrointestinal disease are generally thought to be uncommon, although an increasing number of previously unidentified associations are being established. These neurologic disorders may result from nutritional or non-nutritional causes. In the absence of clear malnutrition, it is like...

journal_title：Neurologic clinics

authors： Albers JW,Nostrant TT,Riggs JE

更新日期：1989-08-01 00:00:00

abstract：:Neurologic symptoms are a prominent and often disturbing component of the migraine syndrome in many patients. Collectively termed "aura," migraine-related neurologic symptoms include visual, sensory, language, and motor disturbance. They occur in about one quarter of migraine patients, are classically transient, and a...

journal_title：Neurologic clinics

authors： Foroozan R,Cutrer FM

更新日期：2009-05-01 00:00:00

abstract：:Considerable evidence exists of hypothalamic dysfunction in patients with anorexia nervosa and bulimia nervosa. This dysfunction is reflected in disturbances of endocrine function including abnormalities of gonadotropin, growth hormone, and corticotropin-releasing hormone secretion. Whereas these disturbances are gene...

journal_title：Neurologic clinics

authors： Newman MM,Halmi KA

更新日期：1988-02-01 00:00:00