Treatment issues for women with epilepsy.

abstract：:A specific genetic diagnosis can be reached for most children with muscular dystrophy. Advanced diagnostics, including genetic testing and analysis of nonmuscle tissues, such as skin and blood, often allow the diagnosis to be reached using minimally invasive procedures. These diagnostic advances accompany improved und...

journal_title：Neurologic clinics

authors： Mathews KD

更新日期：2003-11-01 00:00:00

abstract：:Animal and human research has clearly shown that anticonvulsants are teratogens and pose a risk for fetal malformations. In the case of dilantin it appears that fetal susceptibility correlates with the fetal level of the microsomal detoxifying enzyme epoxide hydrolase. The genetics of seizures in the parents does not ...

journal_title：Neurologic clinics

authors： Buehler BA,Rao V,Finnell RH

更新日期：1994-11-01 00:00:00

abstract：:Traumatic injury to the posterior fossa is a complex pathologic condition because of the great heterogeneity of lesions present. Treatment of primary brain injuries and prevention of secondary brain injuries is the mainstay of management. It is imperative to recognize traumatic lesions of the posterior fossa early bec...

journal_title：Neurologic clinics

authors： Nixon M,Ambekar S,Zhang S,Markham C,Akbarian-Tefaghi H,Morrow K,Nanda A,Guthikonda B

更新日期：2014-11-01 00:00:00

abstract：:In this article, the authors provide a conceptual framework in which to consider alternative approaches to identify the developmental consequences of exposing the developing brain to neurotoxic substances. Concepts underlying brain development and issues regarding neurobehavioral testing in children are reviewed. In a...

journal_title：Neurologic clinics

authors： Trask CL,Kosofsky BE

更新日期：2000-08-01 00:00:00

abstract：:Cerebral ischemia manifests widely in patient symptoms. Along with the clinical examination, imaging serves as a powerful tool throughout the course of ischemia-from acute onset to evolution. A thorough understanding of imaging modalities, their strengths and their limitations, is essential for capitalizing on the ben...

journal_title：Neurologic clinics

authors： Nour M,Liebeskind DS

更新日期：2014-02-01 00:00:00

abstract：:Parasomnias are classified into nonrapid eye movement and rapid eye movement sleep parasomnias. It is important for the clinician to consider other parasomnia mimics that present to the sleep disorders clinic. These conditions can be differentiated by taking a detailed sleep history and conducting nocturnal polysomnog...

journal_title：Neurologic clinics

authors： Malhotra RK,Avidan AY

更新日期：2012-11-01 00:00:00

abstract：:Postamputation phenomena, including painful and nonpainful phantom sensations occur following loss of limbs and other body parts. Peripheral and central nervous system mechanisms play a role in persistent phantom pain. Understanding the pathophysiology of this syndrome has improved in recent years. Comprehensive evalu...

journal_title：Neurologic clinics

authors： Weinstein SM

更新日期：1998-11-01 00:00:00

abstract：:Spontaneous ICH remains a formidable disease that continues to disable and kill the majority of its victims. Treatment of the disease continues to be controversial and without any proved success, such as improvement in the disease mortality or the resulting disability in survivors. Primary prevention is the most effec...

journal_title：Neurologic clinics

authors： Hsieh PC,Awad IA,Getch CC,Bendok BR,Rosenblatt SS,Batjer HH

更新日期：2006-11-01 00:00:00

abstract：:Dementia, defined as progressive cognitive decline, is a feature of a wide variety of genetic disorders. For example, a search of "dementia" in the Online Mendelian Inheritance in Man (www.ncbi.nlm.nih.gov/Omim) reveals 162 entries. Therefore this article cannot be encyclopedic and will be necessarily restricted to mo...

journal_title：Neurologic clinics

authors： Hedera P,Turner RS

更新日期：2002-08-01 00:00:00

abstract：:Neurologic emergencies are common among cancer patients and their incidence is increasing as patients live longer as a result of improved antineoplastic therapy. This article reviews acute neurologic complications in cancer patients. Among those complications reviewed are brain metastases, epidural spinal cord compres...

journal_title：Neurologic clinics

authors： Schiff D,Batchelor T,Wen PY

更新日期：1998-05-01 00:00:00

abstract：:The major clinical uses for opioids are to control pain, suppress cough, and to treat diarrhea. These drugs, however, have the potential for abuse. It is postulated that the significant mood-altering effects of opioids combined with their pharmacology, in which tolerance and physical and psychological dependence occur...

journal_title：Neurologic clinics

authors： Foley KM

更新日期：1993-08-01 00:00:00

abstract：:Myasthenia gravis is an autoimmune disorder characterized by fluctuating weakness of extraocular and proximal limb muscles. It occurs in 1 in 5000 in the overall population and is 2 times more common in women than men. The onset in women is most common in the third decade, and risk of severe exacerbation occurs most f...

journal_title：Neurologic clinics

authors： Waters J

更新日期：2019-02-01 00:00:00

abstract：:Intensive care unit-acquired weakness (ICUAW) is a substantial contributor to long-term disability in survivors of critical illness. Critical illness polyneuropathy, critical illness myopathy, and muscle atrophy from disuse contribute in various proportions to ICUAW. ICUAW is a clinical diagnosis supported by electrop...

journal_title：Neurologic clinics

authors： Kramer CL

更新日期：2017-11-01 00:00:00

abstract：:Personal experience indicates we sleep differently when sick. Data reviewed demonstrate the extent to which sleep is altered during the course of infection of host organisms by several classes of pathogens. One important unanswered question is whether or not the alterations in sleep during infection are of functional ...

journal_title：Neurologic clinics

authors： Opp MR

更新日期：2006-08-01 00:00:00

abstract：:Approximately 2 per cent of organ transplant recipients develop primary CNS lymphomas. There is no pathognomonic clinical or radiographic presentation of the tumor, although multicentric involvement of deep white matter is common. Evidence has linked PCNSL to immunosuppression and to infection with the EBV. The most r...

journal_title：Neurologic clinics

authors： Patchell RA

更新日期：1988-05-01 00:00:00

abstract：:As I have indicated in the foregoing discussion, there are several syndromes that with various degrees of proof seem to be caused by unilateral vascular compression of a cranial nerve at the brain stem. Jannetta has summarized this concept as follows: "As we age, our arteries elongate and our brains 'sag'. As a conseq...

journal_title：Neurologic clinics

authors： Wilkins RH

更新日期：1985-05-01 00:00:00

abstract：:Our recommendations for the evaluation of the patient with suspected cardiogenic syncope are as follows: An initial thorough history and physical examination of the patient will suggest the diagnosis of cardiogenic syncope in at least 50 per cent of patients. A sudden occurrence of syncope, or "drop attack", is most s...

journal_title：Neurologic clinics

authors： Dohrmann ML,Cheitlin MD

更新日期：1986-08-01 00:00:00

abstract：:The last 2 decades represent a period of unparalleled advancement in the understanding of the pathogenesis of Parkinson disease (PD). The discovery of several forms of familial parkinsonism with mendelian inheritance has elucidated insights into the mechanisms underlying the degeneration of dopaminergic neurons of the...

journal_title：Neurologic clinics

authors： Mullin S,Schapira AH

更新日期：2015-02-01 00:00:00

abstract：:Traumatic brain injury is a common and complex clinical entity that deserves better and continued research on interventions and initial treatment postinjury. Current medical management of traumatic brain injury is articulated on minimizing secondary injury by optimizing cerebral perfusion and oxygenation and preventin...

journal_title：Neurologic clinics

authors： Ling GS,Marshall SA

更新日期：2008-05-01 00:00:00

abstract：:Metabolic and mitochondrial myopathies encompass a heterogeneous group of disorders that result in impaired energy production in skeletal muscle. Symptoms of premature muscle fatigue, sometimes leading to myalgia, rhabdomyolysis, and myoglobinuria, typically occur with exercise that would normally depend on the defect...

journal_title：Neurologic clinics

authors： Sharp LJ,Haller RG

更新日期：2014-08-01 00:00:00

abstract：:Cerebellar ataxia can be caused by a variety of disorders, including degenerative processes, autoimmune and paraneoplastic illness as well as by gene mutations inherited in autosomal dominant, autosomal recessive, or X-linked fashions. In this review, we highlight the treatments for cerebellar ataxia in a systematic w...

journal_title：Neurologic clinics

authors： Kwei KT,Kuo SH

更新日期：2020-05-01 00:00:00

abstract：:Encephalitis is an acute infection of brain parenchyma characterized clinically by fever, headache, and an altered level of consciousness. There may also be focal or multifocal neurologic deficits, and focal or generalized seizure activity. This article discusses the clinical presentation, diagnosis, and treatment of ...

journal_title：Neurologic clinics

authors： Roos KL

更新日期：1999-11-01 00:00:00

abstract：:Transcranial Doppler ultrasonography (TCD) is a noninvasive, bedside, portable tool for assessment of cerebral hemodynamics. Modern TCD head frames allow continuous hands-free emboli detection for risk stratification and assessment of treatment efficacy in several cardiovascular diseases. Identifying a focal stenosis,...

journal_title：Neurologic clinics

authors： Hakimi R,Alexandrov AV,Garami Z

更新日期：2020-02-01 00:00:00

abstract：:Neuroepidemiology is the application of the methods of epidemiology to the problems of clinical neurology. After diagnosis, the most basic characterization of a disease is its frequency. This characterization requires ascertainment of case (numerator) within their population at risk (denominator) to provide incidence,...

journal_title：Neurologic clinics

authors： Kurtzke JF

更新日期：1996-05-01 00:00:00

abstract：:The inflammatory myopathies are a heterogeneous group of disorders with recent evidence demonstrating differences in clinical features, pathologic changes, pathogenesis, and response to therapy. The inflammatory myopathies generally produce predominantly proximal, symmetric muscle weakness and wasting. Additional crit...

journal_title：Neurologic clinics

authors： Kingston WJ,Moxley RT 3rd

更新日期：1988-08-01 00:00:00

abstract：:The nosology of dementia has evolved from the simple distinctions between senility, degenerative dementia, and vascular insults that existed a few decades ago. The differentiation of normal cognitive aging from very mild dementia has sharpened considerably; however, appreciation of the heterogeneity of Alzheimer's dis...

journal_title：Neurologic clinics

authors： Morris JC

更新日期：2000-11-01 00:00:00

abstract：:Nonsurgical, conservative approaches to spine pain include medication and physical therapy. In addition, several invasive procedures have been developed to provide relief when conservative options fail. These include facet joint injection and radiofrequency ablation techniques, translaminar and transforaminal epidural...

journal_title：Neurologic clinics

authors： Levin KH

更新日期：2007-05-01 00:00:00

abstract：:Antidepressants are the most commonly prescribed class of medications in the United States. The clinician should be mindful of the many antidepressants that can produce seizures following an accidental exposure or an overdose. A broader understanding of the seizure potential of antidepressants, combined with the abili...

journal_title：Neurologic clinics

authors： Judge BS,Rentmeester LL

更新日期：2011-08-01 00:00:00

abstract：:Glycogen is a crucial source of energy in the initial stages of muscle activity and during exercise of high intensity. There are 10 well-defined biochemical defects of glycogen metabolism expressed in muscle and affecting the following enzymes: alpha 1,4 glucosidase (glycogenesis type II), debrancher enzyme (III), bra...

journal_title：Neurologic clinics

authors： Servidei S,DiMauro S

更新日期：1989-02-01 00:00:00

abstract：:Traditionally, diseases affecting the motor unit had been subdivided based on anatomic criteria into diseases of the anterior horn cell, the peripheral nerve, the neuromuscular junction, and the muscle itself. For therapeutic considerations, however, a more precise cellular and clinicopathologic characterization of th...

journal_title：Neurologic clinics

authors： Dalakas M

更新日期：1990-02-01 00:00:00