Advanced Symptom Management in Multiple Sclerosis.

abstract：:Tuberous sclerosis is a multisystem disorder characterized by changes primarily involving the skin, eye, and central nervous system. Although the disease often produces mental retardation and seizures, this is not universal, and some patients with tuberous sclerosis lead a relatively normal life. ...

journal_title：Neurologic clinics

authors： Hanno R,Beck R

更新日期：1987-08-01 00:00:00

abstract：:Approximately 2 per cent of organ transplant recipients develop primary CNS lymphomas. There is no pathognomonic clinical or radiographic presentation of the tumor, although multicentric involvement of deep white matter is common. Evidence has linked PCNSL to immunosuppression and to infection with the EBV. The most r...

journal_title：Neurologic clinics

authors： Patchell RA

更新日期：1988-05-01 00:00:00

abstract：:Considerable evidence exists of hypothalamic dysfunction in patients with anorexia nervosa and bulimia nervosa. This dysfunction is reflected in disturbances of endocrine function including abnormalities of gonadotropin, growth hormone, and corticotropin-releasing hormone secretion. Whereas these disturbances are gene...

journal_title：Neurologic clinics

authors： Newman MM,Halmi KA

更新日期：1988-02-01 00:00:00

abstract：:Childhood sleep-wake disorders are common and associated with significant impairment of quality of life. The recent discovery of hypocretin deficiency as the pathophysiologic basis for narcolepsy-cataplexy is likely to spur the development of hypocretin analogs for definitive treatment [82,83]. The link between disrup...

journal_title：Neurologic clinics

authors： Kotagal S

更新日期：2003-11-01 00:00:00

abstract：:Parkinson disease (PD) is well recognized by its motor features of bradykinesia, tremor, rigidity, and gait and balance difficulties. However, PD is also characterized by a myriad of nonmotor symptoms, which may occur even before motor symptoms, early in the course of disease, and throughout the advancing disease. The...

journal_title：Neurologic clinics

authors： Goldman JG,Guerra CM

更新日期：2020-05-01 00:00:00

abstract：:Aggression is a serious medical problem that can place both the patient and the health care provider at risk. Aggression can result from medical, neurologic, and/or psychiatric disorders. A comprehensive patient evaluation is needed. Treatment options include pharmacotherapy as well as nonpharmacologic interventions, ...

journal_title：Neurologic clinics

authors： Lane SD,Kjome KL,Moeller FG

更新日期：2011-02-01 00:00:00

abstract：:Antidepressants are the most commonly prescribed class of medications in the United States. The clinician should be mindful of the many antidepressants that can produce seizures following an accidental exposure or an overdose. A broader understanding of the seizure potential of antidepressants, combined with the abili...

journal_title：Neurologic clinics

authors： Judge BS,Rentmeester LL

更新日期：2011-08-01 00:00:00

abstract：:Vasculitis or angiitis refers to a group of inflammatory disorders of the blood vessels that cause structural damage to the affected vessel, including thickening and weakening of the vessel wall, narrowing of its lumen, and, usually, vascular necrosis. Systemic vasculitis is classified according to the vessel size and...

journal_title：Neurologic clinics

authors： Minagar A,Fowler M,Harris MK,Jaffe SL

更新日期：2010-02-01 00:00:00

abstract：:The needle electromyographic (EMG) examination is a challenging component of the electrophysiologic study. Knowledge of anatomy and physiology, sound EMG technique, and good patient rapport are required. Every muscle sampled by needle EMG is assessed for insertional activity, spontaneous activity, and voluntary motor-...

journal_title：Neurologic clinics

authors： Preston DC,Shapiro BE

更新日期：2002-05-01 00:00:00

abstract：:The calcineurin inhibitors cyclosporine and tacrolimus are used for their immunosuppressive effects. Neurotoxic side effects include tremor, paresthesia, and headache. Rarer neurotoxicities include seizure, posterior reversible encephalopathy syndrome, and encephalopathy. Tacrolimus tends to be more neurotoxic than cy...

journal_title：Neurologic clinics

authors： Coe CL,Horst SN,Izzy MJ

更新日期：2020-11-01 00:00:00

abstract：:Psychiatric disorders occurring in patients with epilepsy are complications, not an essential part of the illness, and may be prevented or ameliorated. Outlined are risk factors and medical treatment and the need for education concerning epilepsy and for encouragement of the patient by the physician. ...

journal_title：Neurologic clinics

authors： Green JB,Mercille RA

更新日期：1984-02-01 00:00:00

abstract：:Overall, the majority of patients with optic pathway tumors will have stable disease regardless if they are radiated or receive chemotherapy. This is a very indolent tumor system and, for the most part, not a threat to life. Because of this, issues regarding appropriate therapeutic approaches have yet to be resolved. ...

journal_title：Neurologic clinics

authors： Cohen ME,Duffner PK

更新日期：1991-05-01 00:00:00

abstract：:The nosology of dementia has evolved from the simple distinctions between senility, degenerative dementia, and vascular insults that existed a few decades ago. The differentiation of normal cognitive aging from very mild dementia has sharpened considerably; however, appreciation of the heterogeneity of Alzheimer's dis...

journal_title：Neurologic clinics

authors： Morris JC

更新日期：2000-11-01 00:00:00

abstract：:A specific genetic diagnosis can be reached for most children with muscular dystrophy. Advanced diagnostics, including genetic testing and analysis of nonmuscle tissues, such as skin and blood, often allow the diagnosis to be reached using minimally invasive procedures. These diagnostic advances accompany improved und...

journal_title：Neurologic clinics

authors： Mathews KD

更新日期：2003-11-01 00:00:00

abstract：:The clinician should be alert to the possibility of cerebrovascular disease in cancer patients who develop signs of diffuse or focal cerebral dysfunction. The cause of cerebrovascular disease can usually be determined by knowing the primary tumor type, extent of metastatic disease, and type of antineoplastic treatment...

journal_title：Neurologic clinics

authors： Rogers LR

更新日期：1991-11-01 00:00:00

abstract：:The autosomal dominant spinocerebellar ataxias are a diverse and clinically heterogeneous group of disorders characterized by degeneration and dysfunction of the cerebellum and its associated pathways. Clinical and diagnostic evaluation can be challenging because of phenotypic overlap among causes, and a stratified an...

journal_title：Neurologic clinics

authors： Shakkottai VG,Fogel BL

更新日期：2013-11-01 00:00:00

abstract：:Eclampsia continues to be a significant cause of maternal and fetal death throughout the world. Neurologists have a specific role to play in the diagnosis and management of patients who have eclampsia, especially those who have recurrent seizures, raised intracranial pressure, and coma. Postpartum patients may be admi...

journal_title：Neurologic clinics

authors： Kaplan PW

更新日期：2004-11-01 00:00:00

abstract：:CTS is a clinically defined syndrome; however, there is value added by an evidence-based electrodiagnostic approach to (1) efficiently confirm the diagnosis (particularly before invasive interventions), (2) to identify neurogenic mimickers or superimposed processes that may influence the response to treatment, and (3)...

journal_title：Neurologic clinics

authors： Watson JC

更新日期：2012-05-01 00:00:00

abstract：:Neuropathies due to nutritional problems can affect certain patient populations and have a varied presentation because of multiple coexistent nutritional deficiencies. Clinicians should consider nutritional neuropathies in patients presenting with neuropathies. Clinicians should be alert for signs and symptoms of neur...

journal_title：Neurologic clinics

authors： Hammond N,Wang Y,Dimachkie MM,Barohn RJ

更新日期：2013-05-01 00:00:00

abstract：:Cervicogenic headache is pain referred to the head from a source in the cervical spine or mediated by cervical nerves. Clinical features allow for no more than a diagnosis of probable cervicogenic headache. Definitive diagnosis requires evidence of a cervical source of pain. For most treatments, the evidence is limite...

journal_title：Neurologic clinics

authors： Bogduk N

更新日期：2014-05-01 00:00:00

abstract：:Toxic myopathies may occur with a variety of prescribed medications, illicit drug abuse, or other toxins. The article discusses an overview of some of the compounds that may cause myopathy, the clinical and laboratory features, histology, mechanisms of action, and potential risk factors of myopathy. The ability to rec...

journal_title：Neurologic clinics

authors： George KK,Pourmand R

更新日期：1997-08-01 00:00:00

abstract：:The etiology of pyogenic infections of the brain and meninges varies principally by age, predisposing causes or conditions, and anatomic site of the infection. An appreciation of these factors, plus the prudent use of noninvasive anatomic diagnostic techniques (such as CT) and examination of the CSF, will provide a ba...

journal_title：Neurologic clinics

authors： Overturf GD

更新日期：1986-02-01 00:00:00

abstract：:Diagnostic testing is of limited value among patients with migraine who present to an emergency department. Various nonopioid, disease-specific treatments are available for patients who present to an emergency department with migraine headache and associated features. Emergency physicians should recognize that the acu...

journal_title：Neurologic clinics

authors： Friedman BW

更新日期：2019-11-01 00:00:00

abstract：:The fourth edition of The Diagnostic and Statistical Manual of Mental Disorders defines delirium as "a reversible state of confusion with a reduced level of consciousness manifest as an inability to focus, sustain or shift attention." Pharmacologic agents are important contributors to delirium in hospitalized elderly ...

journal_title：Neurologic clinics

authors： Hanson MR,Gálvez-Jiménez N

更新日期：2004-05-01 00:00:00

abstract：:The neurologic manifestations of gastrointestinal disease are generally thought to be uncommon, although an increasing number of previously unidentified associations are being established. These neurologic disorders may result from nutritional or non-nutritional causes. In the absence of clear malnutrition, it is like...

journal_title：Neurologic clinics

authors： Albers JW,Nostrant TT,Riggs JE

更新日期：1989-08-01 00:00:00

abstract：:Neurologic emergencies are common among cancer patients and their incidence is increasing as patients live longer as a result of improved antineoplastic therapy. This article reviews acute neurologic complications in cancer patients. Among those complications reviewed are brain metastases, epidural spinal cord compres...

journal_title：Neurologic clinics

authors： Schiff D,Batchelor T,Wen PY

更新日期：1998-05-01 00:00:00

abstract：:Traumatic injury to the posterior fossa is a complex pathologic condition because of the great heterogeneity of lesions present. Treatment of primary brain injuries and prevention of secondary brain injuries is the mainstay of management. It is imperative to recognize traumatic lesions of the posterior fossa early bec...

journal_title：Neurologic clinics

authors： Nixon M,Ambekar S,Zhang S,Markham C,Akbarian-Tefaghi H,Morrow K,Nanda A,Guthikonda B

更新日期：2014-11-01 00:00:00

abstract：:The respiratory system and the central nervous system are interconnected in a delicate balance; disorders in this equilibrium can have devastating consequences. Respiratory dysfunction, whether acute or chronic, may cause neurologic disease, including headache, encephalopathy, and in extreme cases, coma and death. Thi...

journal_title：Neurologic clinics

authors： Kirsch DB,Józefowicz RF

更新日期：2002-02-01 00:00:00

abstract：:Glycogen is a crucial source of energy in the initial stages of muscle activity and during exercise of high intensity. There are 10 well-defined biochemical defects of glycogen metabolism expressed in muscle and affecting the following enzymes: alpha 1,4 glucosidase (glycogenesis type II), debrancher enzyme (III), bra...

journal_title：Neurologic clinics

authors： Servidei S,DiMauro S

更新日期：1989-02-01 00:00:00

abstract：:Neurologic syndromes in AIDS are of four types: infections, para-infections, neoplastic, and paraneoplastic. All levels of the neuraxis can be affected. Neurologic complications may be the initial symptom or the cause of death. Aggressive evaluation, including biopsy of cerebral lesions, is indicated because effective...

journal_title：Neurologic clinics

authors： Britton CB,Miller JR

更新日期：1984-05-01 00:00:00