Late-Onset Alzheimer Disease.

Abstract:

:The oldest-old represent the fastest growing segment of society, and the risk of developing dementia continues to increase with advancing age into the 9th and 10th decades of life. The most common form of dementia in the oldest-old is Alzheimer disease (AD), although there are often mixed pathologies contributing to dementia in addition to amyloid plaques and neurofibrillary tangles. Diagnosing AD in the oldest-old is challenging due to cognitive and physical changes associated with aging. Treatment remains supportive, with current approved medications able to provide modest symptomatic benefit but unable to slow the progression of disease.

journal_name

Neurol Clin

journal_title

Neurologic clinics

authors

Pierce AL,Bullain SS,Kawas CH

doi

10.1016/j.ncl.2017.01.006

subject

Has Abstract

pub_date

2017-05-01 00:00:00

pages

283-293

issue

2

eissn

0733-8619

issn

1557-9875

pii

S0733-8619(17)30006-3

journal_volume

35

pub_type

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