Combinatorial control of gene expression.

abstract：:Our aim was to verify the effects of prednisone related to gastrointestinal motility, intestinal histology, and mucosal mast cells in rats. Two-month-old male Wistar rats were randomly assigned to control group (vehicle) animals receiving saline 0.9% (n = 7) or treated orally with 0.625 mg/kg/day of prednisone (n = 7)...

journal_title：BioMed research international

authors： de Lima MB,Gama LA,Hauschildt AT,Dall'Agnol DJR,Corá LA,Americo MF

更新日期：2017-01-01 00:00:00

abstract：:Hepatitis B virus- (HBV-) associated hepatocellular carcinoma (HCC) is the most common type of liver cancer. However, the underlying mechanism of HCC tumorigenesis is very complicated and HBV-encoded X protein (HBx) has been reported to play the most important role in this process. Activation of downstream signal path...

journal_title：BioMed research international

authors： Hung CM,Huang WC,Pan HL,Chien PH,Lin CW,Chen LC,Chien YF,Lin CC,Leow KH,Chen WS,Chen JY,Ho CY,Hou PS,Chen YJ

更新日期：2014-01-01 00:00:00

abstract：:Non-small-cell lung cancer (NSCLC) patients often develop bone metastases (BM), and the overall survival for these patients is usually perishing. However, a model with high accuracy for predicting the survival of NSCLC with BM is still lacking. Here, we aimed to establish a model based on artificial intelligence for p...

journal_title：BioMed research international

authors： Huang Z,Hu C,Chi C,Jiang Z,Tong Y,Zhao C

更新日期：2020-06-27 00:00:00

abstract：:This investigation was aimed at assessing a possible interaction of a traditional Thai herbal recipe, "Ya-Sa-Marn-Phlae (YSMP)," used for wound treatments with topical antiseptics, povidone-iodine (PI) solution and hydrogen peroxide (H2O2), and effects of THR-SK010 alone and the combinations on Staphylococcus aureus. ...

journal_title：BioMed research international

authors： Chusri S,Tongrod S,Chokpaisarn J,Limsuwan S,Voravuthikunchai SP

更新日期：2014-01-01 00:00:00

abstract：Purpose of Review:Transversus abdominis plane (TAP) block is a regional technique for analgesia of the anterolateral abdominal wall. This review highlights the nomenclature system and recent advances in TAP block techniques and proposes directions for future research. Recent Findings:Ultrasound guidance is now conside...

journal_title：BioMed research international

authors： Tsai HC,Yoshida T,Chuang TY,Yang SF,Chang CC,Yao HY,Tai YT,Lin JA,Chen KY

更新日期：2017-01-01 00:00:00

abstract：:The objective of the current research was to review and update evidence on the dietary effect of the consumption of tagatose in type 2 diabetes, as well as to elucidate the current approach that exists on its production and biotechnological utility in functional food for diabetics. Articles published before July 1, 20...

journal_title：BioMed research international

authors： Guerrero-Wyss M,Durán Agüero S,Angarita Dávila L

更新日期：2018-01-09 00:00:00

abstract：:WalkinSense is a new device designed to monitor walking. The aim of this study was to measure the accuracy and repeatability of the gait analysis performed by the WalkinSense system. Descriptions of values recorded by WalkinSense depicting typical gait in adults are also presented. A bench experiment using the Trublu ...

journal_title：BioMed research international

authors： de Castro MP,Meucci M,Soares DP,Fonseca P,Borgonovo-Santos M,Sousa F,Machado L,Vilas-Boas JP

更新日期：2014-01-01 00:00:00

abstract：:Immunodeficiency is associated with higher cancer incidence. However, it is unknown whether there is a link between immunodeficiency and development of multiple primary malignancies. In the present study we analyse this link focusing on kidney-transplanted patients, as they are at higher risk of developing cancer due ...

journal_title：BioMed research international

authors： Santangelo ML,Criscitiello C,Renda A,Federico S,Curigliano G,Dodaro C,Scotti A,Tammaro V,Calogero A,Riccio E,Pisani A,Carlomagno N

更新日期：2015-01-01 00:00:00

abstract：:Background. Acute graft-versus-host disease (aGVHD) involving skin is one of the most frequent complications of allogeneic hematopoietic stem cell transplantation (alloHSCT), usually diagnosed based on clinical manifestations. So far, skin biopsy with histopathological evaluation is the only method to confirm the diag...

journal_title：BioMed research international

authors： Kaminska-Winciorek G,Czerw T,Kruzel T,Giebel S

更新日期：2016-01-01 00:00:00

abstract：:Farnesyl pyrophosphate synthase (FPPS) plays a vital role in the mevalonate pathway and has been shown to be involved in hypertrophy and cardiovascular diseases. Lentivirus-mediated RNA interference (RNAi) to knock down a gene of interest has become a promising new tool for the establishment of transgenic animals. The...

journal_title：BioMed research international

authors： Yang J,Zhao CZ,Chen B,Chen F,Han J,Hu SJ

更新日期：2015-01-01 00:00:00

abstract：:Aims. To compare the clinical features of endometrial polyps (EPs) between patients with endometriosis (EM) (EM group) and without EM (non-EM group). Methods and Results. Seventy-six cases in the EM group and 133 cases in the non-EM group underwent laparotomy or hysteroscopy and laparoscopy; later, it was confirmed th...

journal_title：BioMed research international

authors： Wang N,Zhang Y,Liu B

更新日期：2016-01-01 00:00:00

abstract：:Acute graft-versus-host disease (aGVHD) is a major complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT) and a major cause of nonrelapse mortality after allo-HSCT. A conditioning regimen plays a pivotal role in the development of aGVHD. To provide a platform for studying aGVHD and evaluating t...

journal_title：BioMed research international

authors： He X,Ye Y,Xu X,Wang J,Huang Y,Weng G,Zhang M,Guo K

更新日期：2016-01-01 00:00:00

abstract：:Introduction. This study aimed to evaluate the effects of resorbable blasting media (RBM) treatment on early stability of orthodontic mini-implants by mechanical, histomorphometric, and histological analyses. Methods. Ninety-six (64 for mechanical study and 32 for histological study and histomorphometric analysis) tit...

journal_title：BioMed research international

authors： Gansukh O,Jeong JW,Kim JW,Lee JH,Kim TW

更新日期：2016-01-01 00:00:00

abstract：:Molecular epidemiology has revealed that Mycobacterium tuberculosis (Mtb), formerly regarded as highly conserved species, displays a considerable degree of genetic variability that can influence the outcome of the disease as well as the innate and adaptive immune response. Recent studies have demonstrated that Mtb fam...

journal_title：BioMed research international

authors： Schierloh P,Klepp L,Vazquez C,Rocha RV,Blanco FC,Balboa L,López B,Ritacco V,Bigi F,Sasiain Mdel C

更新日期：2014-01-01 00:00:00

abstract：:Aim. To explore the effects of curcumin on phosphate carrier (PiC) and its role in protection against doxorubicin induced myocyte toxicity. Methods. Using H9c2 cell line, the cardiotoxic effect of doxorubicin and its mitigation by curcumin were studied. H9c2 cells were cultured with doxorubicin and/or curcumin at vari...

journal_title：BioMed research international

authors： Junkun L,Erfu C,Tony H,Xin L,Sudeep KC,Mingliang Z,Yanqin W,XiangQian Q

更新日期：2016-01-01 00:00:00

abstract：:The aim of this study was to investigate the influence of a topically administered hygienic preparation containing a 3% ethanolic extract of Brazilian green propolis (EEP-B) on oral microflora spectrum changes in a group of patients who underwent common oral surgery procedures. Two gel samples were compared: the teste...

journal_title：BioMed research international

authors： Morawiec T,Mertas A,Wojtyczka RD,Niedzielska I,Dziedzic A,Bubiłek-Bogacz A,Sender J,Wróbel J,Tanasiewicz M,Wesołowski P,Król W

更新日期：2015-01-01 00:00:00

abstract：:Bitterness is an important taste sensation for chickens, which provides useful sensory information for acquisition and selection of diet, and warns them against ingestion of potentially harmful and noxious substances in nature. Bitter taste receptors (T2Rs) mediate the recognition of bitter compounds belonging to a fa...

journal_title：BioMed research international

authors： Su Y,Jie H,Zhu Q,Zhao X,Wang Y,Yin H,Kumar Mishra S,Li D

更新日期：2019-10-31 00:00:00

abstract：:Cholesteatoma is an epidermoid cyst, which is most frequently found in the middle ear. The matrix of cholesteatoma is histologically similar to the matrix of the epidermoid cyst of the skin (atheroma); their epithelium is characterized by hyperproliferation. The c-MYC protooncogene located on chromosome 8q24 encodes a...

journal_title：BioMed research international

authors： Palkó E,Póliska S,Csákányi Z,Katona G,Karosi T,Helfferich F,Penyige A,Sziklai I

更新日期：2014-01-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) and lung cancer, closely related to smoking, are major lung diseases affecting millions of individuals worldwide. The generated gas mixture of smoking is proved to contain about 4,500 components such as carbon monoxide, nicotine, oxidants, fine particulate matter, and aldeh...

journal_title：BioMed research international

authors： Hou W,Hu S,Li C,Ma H,Wang Q,Meng G,Guo T,Zhang J

更新日期：2019-06-24 00:00:00

abstract：:Astragalus membranaceus polysaccharide (APS) components are main ingredients of TCM and have proven efficacy to activate T cells and B cells, enhancing immunity in humans. In this study, elevated cytokine and anti-PD-1 antibody titers were found in mice after immunization with APS. Therefore, phage-display technology ...

journal_title：BioMed research international

authors： Chang FL,Tsai KC,Lin TY,Yang TW,Lo YN,Chen WC,Chang JH,Lu MK,Chiou CT,Chen PH,Yen Y,Pan SL,Lee YC

更新日期：2020-03-03 00:00:00

abstract：:The aims of the present research are to investigate the possible predictors of pancreatic cancer, in particular smoking status, alcohol consumption, hypercholesterolemia, and diabetes mellitus, in patients with histologically confirmed pancreatic carcinoma and to examine the synergism between risk factors. A case-cont...

journal_title：BioMed research international

authors： La Torre G,Sferrazza A,Gualano MR,de Waure C,Clemente G,De Rose AM,Nicolotti N,Nuzzo G,Siliquini R,Boccia A,Ricciardi W

更新日期：2014-01-01 00:00:00

abstract：OBJECT:Video-assisted thoracoscopic sympathectomy is a safe, effective, and minimally invasive procedure for primary hyperhidrosis. This study aims to evaluate long-term results and patients' quality of life and investigate potential variables responsible for compensatory sweating after one-stage bilateral single-port ...

journal_title：BioMed research international

authors： Ibrahim M,Menna C,Andreetti C,Ciccone AM,D'Andrilli A,Maurizi G,Pomes LM,Cassiano F,Venuta F,Rendina EA

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:Conventional surgical techniques of laryngomicrosurgery (LMS) on hemorrhagic vocal polyps are often difficult due to obscuration of the surgical field by inadvertent bleeding from the lesion, and there are often significant amounts of mucosal epithelium loss. Here, we introduce our surgical technique using pu...

journal_title：BioMed research international

authors： Byeon HK,Han JH,Choi BI,Hwang HJ,Kim JH,Choi HS

更新日期：2015-01-01 00:00:00

abstract：:Among uterine structural abnormalities, myomas and adenomyosis represent two distinct, though frequently coexistent entities, with a remarkable prevalence in women of reproductive age. Various mechanisms have been proposed to explain the impact of each of them on reproductive outcome. In respect to myomas, current evi...

journal_title：BioMed research international

authors： Vlahos NF,Theodoridis TD,Partsinevelos GA

更新日期：2017-01-01 00:00:00

abstract：:Stem cell-based therapy has been considered as a promising option in the treatment of ischemic heart disease. Although stem cell administration resulted in the temporary improvement of myocardial contractility in the majority of studies, the formation of new cardiomyocytes within the injured myocardium has not been co...

journal_title：BioMed research international

authors： Belostotskaya G,Hendrikx M,Galagudza M,Suchkov S

更新日期：2020-03-03 00:00:00

abstract：:Blood compatibility of metallocene polyethylene (mPE) was investigated after modifying the surface using hydrochloric acid. Contact angle of the mPE exposed to HCl poses a decrease in its value which indicates increasing wettability and better blood compatibility. Surface of mPE analyzed by using FTIR revealed no sign...

journal_title：BioMed research international

authors： Jaganathan SK,Mohandas H,Sivakumar G,Kasi P,Sudheer T,Avineri Veetil S,Murugesan S,Supriyanto E

更新日期：2014-01-01 00:00:00

abstract：:Trichoderma spp. are important biocontrol filamentous fungi and have tremendous potential in soil bioremediation. In our previous studies, a C2H2 type transcription factor coding gene (thmea1) was cloned from a biocontrol agent T. harzianum Th-33; the encoded sequence of thmea1 contained 3 conserved C2H2 domains with ...

journal_title：BioMed research international

authors： Mei J,Wang L,Jiang X,Wu B,Li M

更新日期：2018-07-18 00:00:00

abstract：:We have developed a new "drug" and approach that appear to be effective in reducing arterial age. This "drug" represents a low, subtherapeutic dose of statin and sartan and particularly their low-dose combination. The improvement of arterial wall characteristics, also reflecting in a decrease of arterial age, was achi...

journal_title：BioMed research international

authors： Janić M,Lunder M,Šabovič M

更新日期：2015-01-01 00:00:00

abstract：:Colorectal cancer is the third most common form of cancer in developed countries and, despite the improvements achieved in its treatment options, remains as one of the main causes of cancer-related death. In this review, we first focus on colorectal carcinogenesis and on the genetic and epigenetic alterations involved...

journal_title：BioMed research international

authors： Lizarbe MA,Calle-Espinosa J,Fernández-Lizarbe E,Fernández-Lizarbe S,Robles MÁ,Olmo N,Turnay J

更新日期：2017-01-01 00:00:00

abstract：Aim:To address the impact of noncavity-distorting intramural fibroids on the efficacy of in vitro fertilization-embryo transfer (IVF-ET) outcomes. Methods:The PubMed, Web of Science, Embase, Cochrane Library, and China National Knowledge Infrastructure were searched systematically. A meta-analysis was performed based ...

journal_title：BioMed research international

authors： Wang X,Chen L,Wang H,Li Q,Liu X,Qi H

更新日期：2018-09-04 00:00:00