The Assessment of Oral Microflora Exposed to 3% Ethanolic Extract of Brazilian Green Propolis Preparation Used for Hygiene Maintenance following Minor Oral Surgeries.

abstract：:Postoperative surgical site infections (SSIs) are more common complications after spinal surgery. SSIs often require extended hospitalisation and may worsen overall clinical outcomes. A retrospective database review of consecutive patients with traditional open lumbar spinal surgery was performed. SSIs patients were i...

journal_title：BioMed research international

authors： Liu JT,Liao WJ,Chang CS,Chen YH

更新日期：2015-01-01 00:00:00

abstract：Background:Gegen Qinlian (GGQL) decoction is a common Chinese herbal compound for the treatment of ulcerative colitis (UC). In this study, we aimed to identify its molecular target and the mechanism involved in UC treatment by network pharmacology and molecular docking. Material and Methods. The active ingredients of P...

journal_title：BioMed research international

authors： Wei M,Li H,Li Q,Qiao Y,Ma Q,Xie R,Wang R,Liu Y,Wei C,Li B,Zheng C,Sun B,Yu B

更新日期：2020-11-24 00:00:00

abstract：:Diesel exhaust and its particles (DEP) have been under scrutiny for health effects in humans. In the development of these effects inflammation is regarded as a key process. Overall, in vitro studies report similar DEP-induced changes in markers of inflammation, including cytokines and chemokines, as studies in vivo. I...

journal_title：BioMed research international

authors： Schwarze PE,Totlandsdal AI,Låg M,Refsnes M,Holme JA,Øvrevik J

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship of delivery type, maternal anesthesia, feeding modalities, and first feeding and meconium passage times with early bilirubin levels of healthy infants. METHODS:Cord, 24 hours' and 48 hours' total bilirubin levels were measured in 388 study infants. RESULTS:Infants born with c...

journal_title：BioMed research international

authors： Siyah Bilgin B,Altun Koroglu O,Yalaz M,Karaman S,Kultursay N

更新日期：2013-01-01 00:00:00

abstract：Background:The mechanism of inflammatory reaction after intracerebral hemorrhage remains unclear, which to some extent restrains the therapeutic development of hemorrhagic stroke. The present study attempts to verify whether NLRP6 plays an important role in inflammatory reaction after intracerebral hemorrhage and ident...

journal_title：BioMed research international

authors： Nie H,Hu Y,Guo W,Wang W,Yang Q,Dong Q,Tang Y,Li Q,Tang Z

更新日期：2020-06-07 00:00:00

abstract：:One of the most common complications of diabetes mellitus is diabetic neuropathy. It may be provoked by metabolic and/or vascular factors, and depending on duration of disease, various layers of nerve may be affected. Our aim was to investigate influence of diabetes on the epineurial, perineurial, and endoneurial conn...

journal_title：BioMed research international

authors： Kundalić B,Ugrenović S,Jovanović I,Stefanović N,Petrović V,Kundalić J,Stojanović V,Živković V,Antić V

更新日期：2014-01-01 00:00:00

abstract：:Background. The aim of this study was to assess the effects of low concentrations of H2O2 on angiogenesis of human umbilical vein endothelial cells (HUVECs) in vitro and explore the underlying mechanisms. Methods. HUVECs were cultured and stimulated with different concentrations of H2O2. Flow cytometric analysis was u...

journal_title：BioMed research international

authors： Jiang S,Zhang D,Huang H,Lei Y,Han Y,Han W

更新日期：2017-01-01 00:00:00

abstract：:Probiotic Lactobacillus casei Shirota (LcS) is a potential decontaminating agent of aflatoxin B1 (AFB1). However, few studies have investigated the influence of diet, especially a high protein (HP) diet, on the binding of AFB1 by probiotics. This research was conducted to determine the effect of HP diet on the ability...

journal_title：BioMed research international

authors： Nurul Adilah Z,Liew WP,Mohd Redzwan S,Amin I

更新日期：2018-05-23 00:00:00

abstract：:The regulation of transcriptome expression level is a complex process involving multiple-level interactions among molecules such as protein coding RNA (mRNA), long noncoding RNA (lncRNA), and microRNA (miRNA), which are essential for the transcriptome stability and maintenance and regulation of body homeostasis. The a...

journal_title：BioMed research international

authors： Liu C,Zhang YH,Deng Q,Li Y,Huang T,Zhou S,Cai YD

更新日期：2017-01-01 00:00:00

abstract：:RRM2B gene encodes ribonucleoside-diphosphate reductase subunit M2 B, the p53-inducible small subunit (p53R2) of ribonucleotide reductase (RNR), an enzyme catalyzing dNTP synthesis for mitochondrial DNA. Defects in this gene may cause severe mitochondrial disease affecting mainly the nervous system. This study is aime...

journal_title：BioMed research international

authors： Ait El Cadi C,Krami AM,Charoute H,Elkarhat Z,Sifeddine N,Lakhiari H,Rouba H,Barakat A,Nahili H

更新日期：2020-07-25 00:00:00

abstract：AIM:To investigate the role and mechanism of miR-15b in the proliferation and apoptosis of glioma. METHODS:The miR-15b mimics were transfected into human glioma cells to upregulate the miR-15b expression. Cyclin D1 was determined by both western blotting analysis and luciferase reporter assay. Methylthiazol tetrazoliu...

journal_title：BioMed research international

authors： Sun G,Shi L,Yan S,Wan Z,Jiang N,Fu L,Li M,Guo J

更新日期：2014-01-01 00:00:00

abstract：:This study introduced a combined computational fluid dynamics (CFD) and echocardiography methodology to simulate blood flow in the single right ventricle (SRV) and normal ventricles to study the intraventricular flow. Derived from echocardiographic image loops, CFD-based three-dimensional (3D) flow models of normal su...

journal_title：BioMed research international

authors： Chen LJ,Tong ZR,Wang Q,Zhang YQ,Liu JL

更新日期：2018-01-16 00:00:00

abstract：:Majority of gram negative pathogenic bacteria are responsible for extended spectrum β-lactamases (ESBLs) production, which show resistance to some newer generation of antibiotics. The study was aimed at evaluating the prevalence of ESBL and antibiotic susceptibility pattern of Pseudomonas isolates collected during 201...

journal_title：BioMed research international

authors： Ahmad M,Hassan M,Khalid A,Tariq I,Asad MH,Samad A,Mahmood Q,Murtaza G

更新日期：2016-01-01 00:00:00

abstract：:The similarity-based retrieval of lung nodule computed tomography (CT) images is an important task in the computer-aided diagnosis of lung lesions. It can provide similar clinical cases for physicians and help them make reliable clinical diagnostic decisions. However, when handling large-scale lung images with a gener...

journal_title：BioMed research international

authors： Pan L,Qiang Y,Yuan J,Wu L

更新日期：2016-01-01 00:00:00

abstract：:Primary cilia are organelles protruding from cell surface into environment that function in regulating cell cycle and modulating cilia-related signal. Primary ciliogenesis and autophagy play important roles in tumorigenesis. However, the functions and interactions between primary cilia and autophagy in hepatocellular ...

journal_title：BioMed research international

authors： Liu L,Sheng JQ,Wang MR,Gan Y,Wu XL,Liao JZ,Tian DA,He XX,Li PY

更新日期：2019-10-02 00:00:00

abstract：:In response to cytokine signalling and other factors, CD4-positive T lymphocytes differentiate into distinct populations that are characterized by the production of certain cytokines and are controlled by different master transcription factors. The spectrum of such populations, which was initially limited to Th1 and T...

journal_title：BioMed research international

authors： Ivanova EA,Orekhov AN

更新日期：2015-01-01 00:00:00

abstract：:This paper represents data of long-term open prospective study. 312 male clean-up workers, who participated in elimination of the Chernobyl disaster consequences in 1986-87, were observed and examined in Moscow Research Institute of Psychiatry. The average age of patients was 57,0 ± 6,8 years. All patients were diagno...

journal_title：BioMed research international

authors： Krasnov V,Kryukov V,Samedova E,Emelianova I,Ryzhova I

更新日期：2015-01-01 00:00:00

abstract：Introduction:Baseline neutrophil-to-lymphocyte ratio (NLR) has been repeatedly reported as a significant prognostic factor in advanced cancer patients. We explored whether changes in NLR may predict outcome of advanced cancer patients enrolled into phase 1 trials and treated with PD-1/PD-L1 inhibitors. Patients and Me...

journal_title：BioMed research international

authors： Moschetta M,Uccello M,Kasenda B,Mak G,McClelland A,Boussios S,Forster M,Arkenau HT

更新日期：2017-01-01 00:00:00

abstract：:Hepatic fibrosis is a leading cause of morbidity and mortality worldwide. Hepatic fibrosis is usually associated with chronic liver diseases caused by infection, drugs, metabolic disorders, or autoimmune imbalances. Effective clinical therapies are still lacking. Autophagy is a cellular process that degrades damaged o...

journal_title：BioMed research international

authors： Song Y,Zhao Y,Wang F,Tao L,Xiao J,Yang C

更新日期：2014-01-01 00:00:00

abstract：:To explore the antitumor effect of hypoxia-inducible factor-1α short hairpin RNA (HIF-1α shRNA) delivered by ultrasound targeted microbubble destruction (UTMD) and transcatheter arterial embolization (TAE) on rats with hepatic cancer. After the models of transplantation hepatoma were established, Wistar rats were rand...

journal_title：BioMed research international

authors： Liao Y,Luo H,He Z,Kuang Y,Chen P,Zhang X,Chen J,Wen Q,Xie Y,Ding S

更新日期：2019-02-19 00:00:00

abstract：Background:According to several studies, the autoimmune response may lead to osteoarthritis and dyslipidemia and may affect the homeostasis of the human body's internal environment and then cause its own immune regulation. Consequently, the risk of osteoarthritis might be increased by dyslipidemia, but this association...

journal_title：BioMed research international

authors： Xiong J,Long J,Chen X,Li Y,Song H

更新日期：2020-02-15 00:00:00

abstract：PURPOSE:Suppressor of cytokine signaling 7 (SOCS7) is a member of the SOCS family and is known to interact with phospholipase Cγ-1 (PLCγ-1), a key downstream mediator of the hepatocyte growth factor (HGF)/C-MET axis. Here, we report our observations of the effect of knocking down SOCS7 gene on the behaviour of breast c...

journal_title：BioMed research international

authors： Sasi W,Ye L,Jiang WG,Sharma AK,Mokbel K

更新日期：2014-01-01 00:00:00

abstract：:Introduction. The lateral lumbar interbody fusion (LLIF) surgical approach has potential advantages over other approaches but is associated with some unique neurologic risks due to the proximity of the lumbosacral plexus. The present study analyzed complications following LLIF surgical approach using a novel single fl...

journal_title：BioMed research international

authors： Nunley P,Sandhu F,Frank K,Stone M

更新日期：2016-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2016/2643862.]. ...

journal_title：BioMed research international

authors： Cheng LG,He W,Zhang HX,Song Q,Ning B,Li HZ,He Y,Lin S

更新日期：2017-01-01 00:00:00

abstract：:We use hydrophobic poly(lactic-co-glycolic) acid (PLGA) to encapsulate hydrophilic ofloxacin to form drug loading microspheres. Hyaluronic acid (HA) and polylysine (Pls) were used as internal phase additives to see their influences on the drug loading and releasing. Double emulsion (water-in-oil-in-water) solvent extr...

journal_title：BioMed research international

authors： Wu G,Chen L,Li H,Deng CL,Chen XF

更新日期：2014-01-01 00:00:00

abstract：:Constitutive activation of Akt is believed to be an oncogenic signal in multiple myeloma and is associated with poor patient prognosis and resistance to available treatment. The stability of Akt proteins is regulated by phosphorylating the highly conserved turn motif (TM) of these proteins and the chaperone protein HS...

journal_title：BioMed research international

authors： Zhang Y,Fu Y,Zhang F,Liu J

更新日期：2014-01-01 00:00:00

abstract：:Non-VKA oral anticoagulants (NOACs) have now widely reached the lucrative market of anticoagulation. While the marketing authorization holders claimed that no routine monitoring is required and that these compounds can be given at fixed doses, several evidences arisen from the literature tend to demonstrate the opposi...

journal_title：BioMed research international

authors： Douxfils J,Mani H,Minet V,Devalet B,Chatelain B,Dogné JM,Mullier F

更新日期：2015-01-01 00:00:00

abstract：:Colorectal cancer, a malignant neoplasm that occurs in the colorectal mucosa, is one of the most common types of gastrointestinal cancer. Colorectal cancer has been studied extensively, but the molecular mechanisms of this malignancy have not been characterized. This study identified and verified core genes associated...

journal_title：BioMed research international

authors： Xu H,Ma Y,Zhang J,Gu J,Jing X,Lu S,Fu S,Huo J

更新日期：2020-05-08 00:00:00

abstract：:The proper methylation status of histones is essential for appropriate cell lineage and organogenesis. EZH2, a methyltransferase catalyzing H3K27me3, has been abundantly studied in human and mouse embryonic development. The pig is an increasing important animal model for molecular study and pharmaceutical research. Ho...

journal_title：BioMed research international

authors： Tan B,Hong L,Qiao J,Zhou J,Xing P,Yan G,Zheng E,Cai G,Huang S,Wu Z,Gu T

更新日期：2020-10-05 00:00:00

abstract：:As a major tumor suppressor gene, the role of PinX1 in breast cancer and its molecular mechanism remain unclear. In this study, overexpression of PinX1 was generated in 3 breast cancer cell lines, and knockdown of PinX1 was performed in a nontumorigenic breast cell line. The regulation of PinX1 on cell proliferation a...

journal_title：BioMed research international

authors： Shi R,Zhou JY,Zhou H,Zhao Z,Liang SH,Zheng WL,Ma WL

更新日期：2014-01-01 00:00:00