Non-VKA Oral Anticoagulants: Accurate Measurement of Plasma Drug Concentrations.

abstract：:A search for novel and more efficient therapeutic modalities of inflammatory bowel disease (IBD) is one of the most important tasks of contemporary medicine. The anti-inflammatory action of nicotine in IBD might be therapeutic, but its toxicity due to off-target and nonreceptor effects limited its use and prompted a s...

journal_title：BioMed research international

authors： Chernyavsky AI,Galitovskiy V,Shchepotin IB,Grando SA

更新日期：2014-01-01 00:00:00

abstract：:5-Florouracil (5-FU) is the basic agent used in the treatment of gastric cancer. Capecitabine, a prodrug of 5-FU, displays increased antitumor efficacy compared with 5-FU in the clinic. 5'-Deoxy-5-fluorouracil (5'-DFUR), the metabolite of capecitabine, is converted to 5-FU by the enzyme thymidine phosphorylase (TP), w...

journal_title：BioMed research international

authors： Zhu Y,Xu L,Fan Y,Li C,Zhang Y,Zheng H,Hou K,Qu X,Liu Y

更新日期：2013-01-01 00:00:00

abstract：:Light traps represent the most used attractive system to collect and monitor phlebotomine sand flies. Recent studies have suggested that light traps can be easily upgraded by the use of light-emitting diode (LED) with positive effects on trap design, weight, and battery life. However, scant data on the effect of diffe...

journal_title：BioMed research international

authors： Gaglio G,Napoli E,Arfuso F,Abbate JM,Giannetto S,Brianti E

更新日期：2018-06-27 00:00:00

abstract：BACKGROUND:Delayed union and nonunion are common complications in atypical femoral fractures (AFFs) despite having good fracture fixation. Demineralized bone matrix (DBM) is a successfully proven method for enhancing fracture healing of the long bone fracture and nonunion and should be used in AFFs. This study aimed to...

journal_title：BioMed research international

authors： Kulachote N,Sa-ngasoongsong P,Sirisreetreerux N,Chanplakorn P,Fuangfa P,Suphachatwong C,Wajanavisit W

更新日期：2016-01-01 00:00:00

abstract：:This prospective randomized study is to evaluate the locoregional failure and its impact on survival by comparing involved field radiotherapy (IFRT) with elective nodal irradiation (ENI) in combination with concurrent chemotherapy for locally advanced non-small cell lung cancer. It appears that higher dose could be de...

journal_title：BioMed research international

authors： Chen M,Bao Y,Ma HL,Hu X,Wang J,Wang Y,Peng F,Zhou QC,Xie CH

更新日期：2013-01-01 00:00:00

abstract：:Hepatitis B virus (HBV) infection is the predominant risk factor for chronic hepatitis B (CHB). The association between HBV infection and human leukocyte antigen- (HLA-) DQ polymorphism (rs2856718 and rs7453920) has been demonstrated in other studies; however, the results were controversial or inconclusive. Therefore,...

journal_title：BioMed research international

authors： Xu T,Sun M,Wang H

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:This study investigates the safety and efficacy of a multimodality approach combining staged endovascular embolizations with subsequent SRS for the management of larger AVMs. METHODS:Ninety-five patients with larger AVMs were treated with staged endovascular embolization followed by SRS between 1996 and 2011...

journal_title：BioMed research international

authors： Dalyai R,Theofanis T,Starke RM,Chalouhi N,Ghobrial G,Jabbour P,Dumont AS,Fernando Gonzalez L,Gordon DS,Rosenwasser RH,Tjoumakaris SI

更新日期：2014-01-01 00:00:00

abstract：Objective:To investigate whether preventive administration of a proton pump inhibitor (PPI) can reduce the occurrence and development of traumatic granuloma (TG) following type IV-VI cordectomy. Methods:We retrospectively analyzed the status of postoperative granulomas in 37 patients who underwent type IV-VI cordectom...

journal_title：BioMed research international

authors： Jin X,Niu Y,Gu W,Wang J

更新日期：2020-08-10 00:00:00

abstract：OBJECTIVE:There is an unmet need for a specific cardiovascular risk (CV) algorithm for rheumatoid arthritis (RA) patients. Lipoprotein data are often not available in RA cohorts but could be obtained from frozen blood samples. The objective of this study was to estimate the storage effect on lipoproteins in long-term (...

journal_title：BioMed research international

authors： Arts EE,Popa CD,Smith JP,Arntz OJ,van de Loo FA,Donders R,Semb AG,Kitas GD,van Riel PL,Fransen J

更新日期：2014-01-01 00:00:00

abstract：:Chrysactinia mexicana A. Gray (Asteraceae) and Turnera diffusa Willd (Turneraceae) are employed in traditional medicine as aphrodisiacs; however, there is no scientific evidence supporting the prosexual properties of C. mexicana. The aim of this study was to determine whether an aqueous extract of C. mexicana (Cm) sti...

journal_title：BioMed research international

authors： Estrada-Reyes R,Ferreyra-Cruz OA,Jiménez-Rubio G,Hernández-Hernández OT,Martínez-Mota L

更新日期：2016-01-01 00:00:00

abstract：:Despite many advances in the diagnosis and treatment of colorectal cancer (CRC), its incidence and mortality rates continue to make an impact worldwide and in some countries rates are mounting. Over the past decade, liquid biopsies have been the object of fundamental and clinical research with regard to the different ...

journal_title：BioMed research international

authors： Christou N,Meyer J,Popeskou S,David V,Toso C,Buchs N,Liot E,Robert J,Ris F,Mathonnet M

更新日期：2019-12-04 00:00:00

abstract：BACKGROUND:Apoptosis and matrix metalloproteinase (MMP-9) are capable of hydrolysing components of the extracellular matrix and weakening the fetal membranes which leads to eventual rupture, a key process of human parturition. The aim of this study was to determine the effect of supracervical apposition and spontaneous...

journal_title：BioMed research international

authors： Chai M,Walker SP,Riley C,Rice GE,Permezel M,Lappas M

更新日期：2013-01-01 00:00:00

abstract：:Tissue regeneration has become a promising treatment for craniomaxillofacial bone defects such as alveolar clefts. This study sought to assess the efficacy of lateral ramus cortical plate with buccal fat pad derived mesenchymal stem cells (BFSCs) in treatment of human alveolar cleft defects. Ten patients with unilater...

journal_title：BioMed research international

authors： Khojasteh A,Kheiri L,Behnia H,Tehranchi A,Nazeman P,Nadjmi N,Soleimani M

更新日期：2017-01-01 00:00:00

abstract：:Neonatal hyperbilirubinemia is a common problem with potentiality to cause irreversible brain damage. Reduction of serum bilirubin level is essential to minimize such damage. Compact fluorescent tubes, halogen bulbs, fiber optic blankets, and LEDs are commonly used light sources for phototherapy with varying efficacie...

journal_title：BioMed research international

authors： Gutta S,Shenoy J,Kamath SP,Mithra P,Baliga BS,Sarpangala M,Srinivasan M

更新日期：2019-04-11 00:00:00

abstract：:The palmaris longus is considered a phylogenetic degenerate metacarpophalangeal joint flexor muscle in humans, a small vestigial forearm muscle; it is the most variable muscle in humans, showing variation in position, duplication, slips and could be reverted. It is frequently studied in papers about human anatomical v...

journal_title：BioMed research international

authors： Aversi-Ferreira RA,Bretas RV,Maior RS,Davaasuren M,Paraguassú-Chaves CA,Nishijo H,Aversi-Ferreira TA

更新日期：2014-01-01 00:00:00

abstract：:It is well known that Down syndrome (DS) is a condition in which extra genetic material causes delays in the way a child develops, both mentally and physically. Intellectual disability is the foremost and most debilitating trait, which caused loss of cognitive abilities and the development of early onset Alzheimer's d...

journal_title：BioMed research international

authors： Yu B,Zhang B,Zhou WB,Wang QW,Yuan P,Yang YQ,Kong J

更新日期：2015-01-01 00:00:00

abstract：:Bone grafts are medical devices that are in high demand in clinical practice for substitution of bone defects and recovery of atrophic bone regions. Based on the analysis of the modern groups of bone grafts, the particularities of their composition, the mechanisms of their biological effects, and their therapeutic ind...

journal_title：BioMed research international

authors： Deev RV,Drobyshev AY,Bozo IY,Isaev AA

更新日期：2015-01-01 00:00:00

abstract：:Seeking new biomarkers for epithelial ovarian cancer, the fifth most common cause of death from all cancers in women and the leading cause of death from gynaecological malignancies, we performed a meta-analysis of three independent studies and compared the results in regard to clinicopathological parameters. This anal...

journal_title：BioMed research international

authors： Buehler M,Tse B,Leboucq A,Jacob F,Caduff R,Fink D,Goldstein DR,Heinzelmann-Schwarz V

更新日期：2013-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2016/6935123.]. ...

journal_title：BioMed research international

authors： Pruimboom L,Ruiz-Núñez B,Raison CL,Muskiet FAJ,Freese J

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:In Mexico and other developing countries, few reports of the survival of children with acute leukaemia exist. Objective. We aimed at comparing the disease-free survival of children with acute myeloid leukaemia who, in addition to being treated with the Latin American protocol of chemotherapy and an autologou...

journal_title：BioMed research international

authors： Jiménez-Hernández E,Dueñas-González MT,Arellano-Galindo J,Medrano-Ortíz-De-Zárate ME,Bekker-Méndez VC,Berges-García A,Solís-Labastida K,Sánchez-Jara B,Tiznado-García HM,Jaimes-Reyes EZ,García-Jiménez X,Espinoza-Hernández L,Núñez-

更新日期：2015-01-01 00:00:00

abstract：:Neutrophils comprise the first line of innate immune defense during a host-pathogen interaction. They attack microorganisms directly through three different methods, of which, phagocytosis and degranulation have been known and well-studied for decades. The formation of neutrophil extracellular traps (NETs) is the thir...

journal_title：BioMed research international

authors： Alasmari SZ

更新日期：2020-02-01 00:00:00

abstract：:28 new pyrrolidine types of compounds as analogues for natural polyhydroxy alkaloids of codonopsinine were evaluated for their anti-MRSA activity using MIC and MBC value determination assay against a panel of S. aureus isolates. One pyrrolidine compound, MFM 501, exhibited good inhibitory activity with MIC value of 15...

journal_title：BioMed research international

authors： Johari SA,Mohtar M,Mohammad SA,Sahdan R,Shaameri Z,Hamzah AS,Mohammat MF

更新日期：2015-01-01 00:00:00

abstract：:Chronic Obstructive Pulmonary Disease (COPD) is defined as a disease characterized by persistent, progressive airflow limitation. Recent studies have underlined that COPD is correlated to many systemic manifestations, probably due to an underlying pattern of systemic inflammation. In COPD fractional exhaled Nitric Oxi...

journal_title：BioMed research international

authors： Malerba M,Radaeli A,Olivini A,Damiani G,Ragnoli B,Montuschi P,Ricciardolo FL

更新日期：2014-01-01 00:00:00

abstract：:Purpose. This meta-analysis is to assess the effectiveness of teriparatide in fracture healing and clinical function improvement of the osteoporotic patients. Methods. We searched PubMed, Embase, Web of Science, and the Cochrane databases for randomized and quasi-randomized controlled trials comparing teriparatide to ...

journal_title：BioMed research international

authors： Lou S,Lv H,Wang G,Zhang L,Li M,Li Z,Zhang L,Tang P

更新日期：2016-01-01 00:00:00

abstract：:The incidence of acute kidney injury after cardiac surgery (CS-AKI) ranges from 33% to 94% and is associated with a high incidence of morbidity and mortality. The etiology is suggested to be multifactorial and related to almost all aspects of perioperative management. Numerous studies have reported the risk factors an...

journal_title：BioMed research international

authors： Shin SR,Kim WH,Kim DJ,Shin IW,Sohn JT

更新日期：2016-01-01 00:00:00

abstract：:Ouabain, a cardiac glycoside found in plants, is primarily used in the treatment of congestive heart failure and arrhythmia because of its ability to inhibit Na(+)/K(+)-ATPase pump. Recently ouabain has been shown to exert anticancer effects but the underlying mechanism is not clear. Here, we explored the molecular me...

journal_title：BioMed research international

authors： Shin HK,Ryu BJ,Choi SW,Kim SH,Lee K

更新日期：2015-01-01 00:00:00

abstract：:In a bioprospecting effort towards novel thermostable lipases, we assessed the lipolytic profile of 101 bacterial strains isolated from the volcanic area of Santorini, Aegean Sea, Greece. Screening of lipase activity was performed both in agar plates and liquid cultures using olive oil as carbon source. Significant di...

journal_title：BioMed research international

authors： Stathopoulou PM,Savvides AL,Karagouni AD,Hatzinikolaou DG

更新日期：2013-01-01 00:00:00

abstract：:Mind-body practices (MBP) are known to induce electrophysiological and morphological changes, whereas reports related to changes of neurotrophins are surprisingly scarce. Consequently, in the current paper, we focused on the Quadrato motor training (QMT), a newly developed whole-body movement-based MBP, which has been...

journal_title：BioMed research international

authors： Venditti S,Verdone L,Pesce C,Tocci N,Caserta M,Ben-Soussan TD

更新日期：2015-01-01 00:00:00

abstract：:The use of in vitro metabolism data to predict human clearance has become more significant in the current prediction of large scale drug clearance for all the drugs. The relevant information (in vitro metabolism data and in vivo human clearance values) of thirty-five drugs that satisfied the entry criteria of probe dr...

journal_title：BioMed research international

authors： Wang L,Chiang C,Liang H,Wu H,Feng W,Quinney SK,Li J,Li L

更新日期：2015-01-01 00:00:00

abstract：:Hyaluronic acid (HA), a macropolysaccharidic component of the extracellular matrix, is common to most species and it is found in many sites of the human body, including skin and soft tissue. Not only does HA play a variety of roles in physiologic and in pathologic events, but it also has been extensively employed in c...

journal_title：BioMed research international

authors： Saturnino C,Sinicropi MS,Parisi OI,Iacopetta D,Popolo A,Marzocco S,Autore G,Caruso A,Cappello AR,Longo P,Puoci F

更新日期：2014-01-01 00:00:00