The Impact of Noncavity-Distorting Intramural Fibroids on the Efficacy of In Vitro Fertilization-Embryo Transfer: An Updated Meta-Analysis.

Abstract:

Aim:To address the impact of noncavity-distorting intramural fibroids on the efficacy of in vitro fertilization-embryo transfer (IVF-ET) outcomes. Methods:The PubMed, Web of Science, Embase, Cochrane Library, and China National Knowledge Infrastructure were searched systematically. A meta-analysis was performed based on comparative or cohort studies that explored the impact of noncavity-distorting intramural fibroids on the efficacy of IVF-ET treatment. The IVE-ET outcomes of study group (women with noncavity-distorting intramural fibroids) and control group (women without fibroids) were compared, including live birth rate (LBR), clinical pregnancy rate (cPR), implantation rate (IR) , miscarriage rate (MR), and ectopic pregnancy rate (ePR). Results:A total of 28 studies involving 9189 IVF cycles were included. Our meta-analysis showed a significant reduction of LBR in the study group compared to control group (RR = 0.82, 95% CI: 0.73-0.92, and P = 0.005). In addition, it indicated that study group had a significant reduction in cPR (RR = 0.86, 95% CI: 0.80-0.93, P = 0.0001) and IR (RR = 0.90, 95% CI: 0813-1.00, P = 0.04) and have a significantly increase in MR (RR = 1.27, 95% CI: 1.08-1.50, and P = 0.004) compared with control group. Conclusions:The present evidence suggests that noncavity-distorting intramural fibroids would significantly reduce the IR, cRP, and LBR and significantly increase the MR after IVF treatment, but it would not significantly increase the ePR.

journal_name

Biomed Res Int

authors

Wang X,Chen L,Wang H,Li Q,Liu X,Qi H

doi

10.1155/2018/8924703

subject

Has Abstract

pub_date

2018-09-04 00:00:00

pages

8924703

eissn

2314-6133

issn

2314-6141

journal_volume

2018

pub_type

杂志文章,meta分析
  • The Alcohol Extract of Coreopsis tinctoria Nutt Ameliorates Diabetes and Diabetic Nephropathy in db/db Mice through miR-192/miR-200b and PTEN/AKT and ZEB2/ECM Pathways.

    abstract::The study aims to investigate the effects of the alcohol extract of Coreopsis tinctoria Nutt (AC) on diabetic nephropathy (DN) mice. A total of 30 db/db (DN) mice were divided into 3 groups, which were treated with AC (300 mg/kg/day), metformin (180 mg/kg/day), or saline by gavage for 10 weeks. Ten db/m mice treated w...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/5280514

    authors: Yu S,Zhao H,Yang W,Amat R,Peng J,Li Y,Deng K,Mao X,Jiao Y

    更新日期:2019-03-28 00:00:00

  • Lentiviral-mediated silencing of farnesyl pyrophosphate synthase through RNA interference in mice.

    abstract::Farnesyl pyrophosphate synthase (FPPS) plays a vital role in the mevalonate pathway and has been shown to be involved in hypertrophy and cardiovascular diseases. Lentivirus-mediated RNA interference (RNAi) to knock down a gene of interest has become a promising new tool for the establishment of transgenic animals. The...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/914026

    authors: Yang J,Zhao CZ,Chen B,Chen F,Han J,Hu SJ

    更新日期:2015-01-01 00:00:00

  • Serum samples that have been stored long-term (>10 years) can be used as a suitable data source for developing cardiovascular risk prediction models in large observational rheumatoid arthritis cohorts.

    abstract:OBJECTIVE:There is an unmet need for a specific cardiovascular risk (CV) algorithm for rheumatoid arthritis (RA) patients. Lipoprotein data are often not available in RA cohorts but could be obtained from frozen blood samples. The objective of this study was to estimate the storage effect on lipoproteins in long-term (...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/930925

    authors: Arts EE,Popa CD,Smith JP,Arntz OJ,van de Loo FA,Donders R,Semb AG,Kitas GD,van Riel PL,Fransen J

    更新日期:2014-01-01 00:00:00

  • Effect of miR-146a/bFGF/PEG-PEI Nanoparticles on Inflammation Response and Tissue Regeneration of Human Dental Pulp Cells.

    abstract:INTRODUCTION:Inflammation in dental pulp cells (DPCs) initiated by Lipopolysaccharide (LPS) results in dental pulp necrosis. So far, whether there is a common system regulating inflammation response and tissue regeneration remains unknown. miR-146a is closely related to inflammation. Basic fibroblast growth factor (bFG...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/3892685

    authors: Liu L,Shu S,Cheung GS,Wei X

    更新日期:2016-01-01 00:00:00

  • Sera from Visceral Leishmaniasis Patients Display Oxidative Activity and Affect the TNF-α Production by Macrophages In Vitro.

    abstract::Mammalian protection against leishmanial infection depends on the development of an effective immune response. Zoonotic visceral leishmaniasis (ZVL) patients are usually unable to mount an effective immune response against the parasite and indeed appear to be severely immunosuppressed. This suppression has strong nons...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/5861453

    authors: Soares NM,de Souza JN,Leal TF,Reis EAG,Miranda MS,Dos Santos WLC,Teixeira MCA

    更新日期:2017-01-01 00:00:00

  • Extensive Use of 3D Nonfluoroscopic Mapping Systems for Reducing Radiation Exposure during Catheter Ablation Procedures: An Analysis of 10 Years of Activity.

    abstract:Purpose:3D nonfluoroscopic mapping systems (NMSs) are generally used in the catheter ablation (CA) of complex ventricular and atrial arrhythmias. The aim of this study was to evaluate the efficacy, safety, and long-term effect of the extended, routine use of NMSs for CA. Methods:Our study involved 1028 patients who un...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/4217076

    authors: Marini M,Martin M,Ravanelli D,Del Greco M,Quintarelli S,Guarracini F,Coser A,Valentini A,Bonmassari R

    更新日期:2019-03-10 00:00:00

  • Relationship Between Emotional Intelligence and Health Behaviours among University Students: The Predictive and Moderating Role of Gender.

    abstract::This study investigated the role of gender as a potential predictor of health behaviour and potential moderator of the relationship between emotional intelligence and health behaviour. This cross-sectional study included 1214 students (597 males and 617 females). Data were collected using the Schutte Self-Report Inven...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/7058105

    authors: Malinauskas R,Dumciene A,Sipaviciene S,Malinauskiene V

    更新日期:2018-06-04 00:00:00

  • A Novel Mouse Model of Peritoneal Dialysis: Combination of Uraemia and Long-Term Exposure to PD Fluid.

    abstract::Different animal models for peritoneal dialysis (PD) have been used in the past decades to develop PD fluids compatible with patient life and to identify markers of peritoneal fibrosis and inflammation. Only few of those studies have taken into account the importance of uraemia-induced alterations at both systemic and...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/106902

    authors: Ferrantelli E,Liappas G,Keuning ED,Vila Cuenca M,González-Mateo G,Verkaik M,López-Cabrera M,Beelen RH

    更新日期:2015-01-01 00:00:00

  • Elevated miRNA Inversely Correlates with E-cadherin Gene Expression in Tissue Biopsies from Crohn Disease Patients in contrast to Ulcerative Colitis Patients.

    abstract::Inflammatory bowel disease (IBD) comprises ulcerative colitis (UC) and Crohn disease (CD). Similar symptoms, but different treatment procedures for both diseases require precise diagnosis. MicroRNAs (miRNAs) are major posttranscriptional players that regulate the expression of genes during the inflammation and thus co...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/4250329

    authors: Guz M,Dworzański T,Jeleniewicz W,Cybulski M,Kozicka J,Stepulak A,Celiński K

    更新日期:2020-07-22 00:00:00

  • Effect of supracervical apposition and spontaneous labour on apoptosis and matrix metalloproteinases in human fetal membranes.

    abstract:BACKGROUND:Apoptosis and matrix metalloproteinase (MMP-9) are capable of hydrolysing components of the extracellular matrix and weakening the fetal membranes which leads to eventual rupture, a key process of human parturition. The aim of this study was to determine the effect of supracervical apposition and spontaneous...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/316146

    authors: Chai M,Walker SP,Riley C,Rice GE,Permezel M,Lappas M

    更新日期:2013-01-01 00:00:00

  • T Helper Lymphocyte Subsets and Plasticity in Autoimmunity and Cancer: An Overview.

    abstract::In response to cytokine signalling and other factors, CD4-positive T lymphocytes differentiate into distinct populations that are characterized by the production of certain cytokines and are controlled by different master transcription factors. The spectrum of such populations, which was initially limited to Th1 and T...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2015/327470

    authors: Ivanova EA,Orekhov AN

    更新日期:2015-01-01 00:00:00

  • Evaluation of electromagnetic interference and exposure assessment from s-health solutions based on Wi-Fi devices.

    abstract::In the last decade the number of wireless devices operating at the frequency band of 2.4 GHz has increased in several settings, such as healthcare, occupational, and household. In this work, the emissions from Wi-Fi transceivers applicable to context aware scenarios are analyzed in terms of potential interference and ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/784362

    authors: de Miguel-Bilbao S,Aguirre E,Lopez Iturri P,Azpilicueta L,Roldán J,Falcone F,Ramos V

    更新日期:2015-01-01 00:00:00

  • Effect of Physical Activity on Cognitive Development: Protocol for a 15-Year Longitudinal Follow-Up Study.

    abstract::The aim of the study is to investigate the relationship between physical activity as assessed by accelerometers and cognitive development across the human age ranges (from children and adolescents to adults). Additionally, this study seeks to explore whether physical activity contributes to cognitive development via m...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/8568459

    authors: Zhao G,Quan M,Su L,Zhang H,Zhang J,Zhang J,Fang H,Cao ZB,Zhu Z,Niu Z,Wang R,Chen P

    更新日期:2017-01-01 00:00:00

  • Diagnostic Potential of Evaluation of SDF-1α and sRAGE Levels in Threatened Premature Labor.

    abstract::Preterm birth remains the most prevalent cause of neonatal morbidity. This study aimed to evaluate the diagnostic value of SDF-1α, resistin, secretory RAGE (sRAGE), and endogenous secretory RAGE (esRAGE) in preterm labor. A total of 211 pregnant women participated in the study. Group A contained 72 women between 22 an...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/2719460

    authors: Rzepka R,Dołęgowska B,Rajewska A,Sałata D,Budkowska M,Kwiatkowski S,Torbé A

    更新日期:2016-01-01 00:00:00

  • Chronic dietary supplementation of 4% figs on the modification of oxidative stress in Alzheimer's disease transgenic mouse model.

    abstract::We assessed the changes in the plasma Aβ, oxidative stress/antioxidants, and membrane bound enzymes in the cerebral cortex and hippocampus of Alzheimer's disease (AD) transgenic mice (Tg2576) after dietary supplementation of Omani figs fruits for 15 months along with spatial memory and learning test. AD Tg mice on con...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/546357

    authors: Subash S,Essa MM,Al-Asmi A,Al-Adawi S,Vaishnav R

    更新日期:2014-01-01 00:00:00

  • Mass Spectrometry Amyloid Typing Is Reproducible across Multiple Organ Sites.

    abstract::We have determined patient's amyloid subtype through immunohistochemical and proteomic analyses of formalin-fixed, paraffin-embedded (FFPE) tissue samples from two affected organs per patient. Amyloid typing, via immunohistochemistry (IHC) and laser microdissection followed by the combination of liquid chromatography ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/3689091

    authors: Holub D,Flodrova P,Pika T,Flodr P,Hajduch M,Dzubak P

    更新日期:2019-01-31 00:00:00

  • Evaluation of Laser Speckle Contrast Imaging for the Assessment of Oral Mucosal Blood Flow following Periodontal Plastic Surgery: An Exploratory Study.

    abstract::The laser speckle contrast imaging (LSCI) is proved to be a reliable tool in flap monitoring in general surgery; however, it has not been evaluated in oral surgery yet. We applied the LSCI to compare the effect of a xenogeneic collagen matrix (Geistlich Mucograft®) to connective tissue grafts (CTG) on the microcircula...

    journal_title:BioMed research international

    pub_type: 临床试验,杂志文章

    doi:10.1155/2017/4042902

    authors: Molnár E,Molnár B,Lohinai Z,Tóth Z,Benyó Z,Hricisák L,Windisch P,Vág J

    更新日期:2017-01-01 00:00:00

  • The domain landscape of virus-host interactomes.

    abstract::Viral infections result in millions of deaths in the world today. A thorough analysis of virus-host interactomes may reveal insights into viral infection and pathogenic strategies. In this study, we presented a landscape of virus-host interactomes based on protein domain interaction. Compared to the analysis at protei...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/867235

    authors: Zheng LL,Li C,Ping J,Zhou Y,Li Y,Hao P

    更新日期:2014-01-01 00:00:00

  • Elevated expression of fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) in the dorsal root ganglia and spinal cord in experimental autoimmune encephalomyelitis: implications in multiple sclerosis-induced neuropathic pain.

    abstract::Multiple sclerosis (MS) is a central nervous system (CNS) disease resulting from a targeted autoimmune-mediated attack on myelin proteins in the CNS. The release of Th1 inflammatory mediators in the CNS activates macrophages, antibodies, and microglia resulting in myelin damage and the induction of neuropathic pain (N...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/480702

    authors: Zhu W,Acosta C,MacNeil B,Cortes C,Intrater H,Gong Y,Namaka M

    更新日期:2013-01-01 00:00:00

  • The Yemeni Brown Algae Dictyota dichotoma Exhibit High In Vitro Anticancer Activity Independent of Its Antioxidant Capability.

    abstract::The aim of this study was to investigate the anticancer and antioxidant activities as well as the safety of the brown algae Dictyota dichotoma of the Western seacoast of Yemen. Cytotoxicity of methanol extract of D. dichotoma and several of its fractions, petroleum ether, chloroform, ethyl acetate, n-butanol, and aque...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/2425693

    authors: El-Shaibany A,Al-Habori M,Al-Maqtari T,Al-Mahbashi H

    更新日期:2020-02-17 00:00:00

  • Prevalence of gene rearrangements in Mexican children with acute lymphoblastic leukemia: a population study-report from the Mexican Interinstitutional Group for the identification of the causes of childhood leukemia.

    abstract::Mexico has one of the highest incidences of childhood leukemia worldwide and significantly higher mortality rates for this disease compared with other countries. One possible cause is the high prevalence of gene rearrangements associated with the etiology or with a poor prognosis of childhood acute lymphoblastic leuke...

    journal_title:BioMed research international

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1155/2014/210560

    authors: Bekker-Méndez VC,Miranda-Peralta E,Núñez-Enríquez JC,Olarte-Carrillo I,Guerra-Castillo FX,Pompa-Mera EN,Ocaña-Mondragón A,Rangel-López A,Bernáldez-Ríos R,Medina-Sanson A,Jiménez-Hernández E,Amador-Sánchez R,Peñaloza-González JG,

    更新日期:2014-01-01 00:00:00

  • Multiparametric MRI and Computational Modelling in the Assessment of Human Articular Cartilage Properties: A Comprehensive Approach.

    abstract::Quantitative magnetic resonance imaging (qMRI) is a promising approach to detect early cartilage degeneration. However, there is no consensus on which cartilage component contributes to the tissue's qMRI signal properties. T1, T1ρ, and T2⁎ maps of cartilage samples (n = 8) were generated on a clinical 3.0-T MRI system...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/9460456

    authors: Thüring J,Linka K,Itskov M,Knobe M,Hitpaß L,Kuhl C,Truhn D,Nebelung S

    更新日期:2018-05-15 00:00:00

  • Genotype-specific changes in vitamin B6 content and the PDX family in potato.

    abstract::Vitamin B6 is one of the most versatile cofactors in plants and an essential phytonutrient in the human diet that benefits a variety of human health aspects. Although biosynthesis of the vitamin has been well resolved in recent years, the main research is currently based on Arabidopsis thaliana with very little work d...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/389723

    authors: Mooney S,Chen L,Kühn C,Navarre R,Knowles NR,Hellmann H

    更新日期:2013-01-01 00:00:00

  • The immune interplay between the host and the pathogen in Aspergillus fumigatus lung infection.

    abstract::The interplay between Aspergillus fumigatus and the host immune response in lung infection has been subject of studies over the last years due to its importance in immunocompromised patients. The multifactorial virulence factors of A. fumigatus are related to the fungus biological characteristics, for example, structu...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2013/693023

    authors: Sales-Campos H,Tonani L,Cardoso CR,Kress MR

    更新日期:2013-01-01 00:00:00

  • Pathophysiology of spasticity: implications for neurorehabilitation.

    abstract::Spasticity is the velocity-dependent increase in muscle tone due to the exaggeration of stretch reflex. It is only one of the several components of the upper motor neuron syndrome (UMNS). The central lesion causing the UMNS disrupts the balance of supraspinal inhibitory and excitatory inputs directed to the spinal cor...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2014/354906

    authors: Trompetto C,Marinelli L,Mori L,Pelosin E,Currà A,Molfetta L,Abbruzzese G

    更新日期:2014-01-01 00:00:00

  • Improvement in hemodynamic responses to metaboreflex activation after one year of training in spinal cord injured humans.

    abstract::Spinal cord injured (SCI) individuals show an altered hemodynamic response to metaboreflex activation due to a reduced capacity to vasoconstrict the venous and arterial vessels below the level of the lesion. Exercise training was found to enhance circulating catecholamines and to improve cardiac preload and venous ton...

    journal_title:BioMed research international

    pub_type: 临床试验,杂志文章

    doi:10.1155/2014/893468

    authors: Milia R,Roberto S,Marongiu E,Olla S,Sanna I,Angius L,Bassareo P,Pinna M,Tocco F,Concu A,Crisafulli A

    更新日期:2014-01-01 00:00:00

  • New researches and application progress of commonly used optical molecular imaging technology.

    abstract::Optical molecular imaging, a new medical imaging technique, is developed based on genomics, proteomics and modern optical imaging technique, characterized by non-invasiveness, non-radiativity, high cost-effectiveness, high resolution, high sensitivity and simple operation in comparison with conventional imaging modali...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2014/429198

    authors: Chen ZY,Wang YX,Yang F,Lin Y,Zhou QL,Liao YY

    更新日期:2014-01-01 00:00:00

  • Staphylococcus aureus and staphylococcal food-borne disease: an ongoing challenge in public health.

    abstract::Staphylococcal food-borne disease (SFD) is one of the most common food-borne diseases worldwide resulting from the contamination of food by preformed S. aureus enterotoxins. It is one of the most common causes of reported food-borne diseases in the United States. Although several Staphylococcal enterotoxins (SEs) have...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2014/827965

    authors: Kadariya J,Smith TC,Thapaliya D

    更新日期:2014-01-01 00:00:00

  • Optimal Condition to Create Femoral Tunnel Considering Combined Influence of Knee Flexion and Transverse Drill Angle in Anatomical Single-Bundle ACL Reconstruction Using Medial Portal Technique: 3D Simulation Study.

    abstract::There has been no previous study using three-dimensional (3D) measurement on femoral tunnel characteristics according to the combined influence of various flexion angles of knee and transverse drill angles in single-bundle ACL reconstruction with transportal technique. The purpose of this study was to determine optima...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/2643247

    authors: Kim SH,Kim SJ,Choi CH,Kim D,Jung M

    更新日期:2018-07-17 00:00:00

  • LRRK2 G2385R and R1628P mutations are associated with an increased risk of Parkinson's disease in the Malaysian population.

    abstract::The LRRK2 gene has been associated with both familial and sporadic forms of Parkinson's disease (PD). The G2019S variant is commonly found in North African Arab and Caucasian PD patients, but this locus is monomorphic in Asians. The G2385R and R1628P variants are associated with a higher risk of developing PD in certa...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/867321

    authors: Gopalai AA,Lim SY,Chua JY,Tey S,Lim TT,Mohamed Ibrahim N,Tan AH,Eow GB,Abdul Aziz Z,Puvanarajah SD,Viswanathan S,Looi I,Lim SK,Tan LP,Chong YB,Tan CT,Zhao Y,Tan EK,Ahmad-Annuar A

    更新日期:2014-01-01 00:00:00