Self-powered robots to reduce motor slacking during upper-extremity rehabilitation: a proof of concept study.

abstract：PURPOSE:Accurate coil placement over a target area is critical during transcranial magnetic stimulation (TMS), as small deviations can alter testing outcomes. Accordingly, frameless stereotaxic systems (FSS) are recommended for reliable coil placement during TMS applications. However, FSS is not practical due to the co...

journal_title：Restorative neurology and neuroscience

authors： Washabaugh EP,Krishnan C

更新日期：2016-01-01 00:00:00

abstract：:Fetal neocortical block transplants were implanted into the excitotoxically ablated sensorimotor cortex of adult rats in order to examine the density of innervation and distribution of presumptive host derived afferent fibers within these transplants. Cholinergic fiber innervation was examined at 3 months post graftin...

journal_title：Restorative neurology and neuroscience

authors： Schulz MK,McNulty JA,Hogan TP,Zimmer J,Castro AJ

更新日期：1995-01-01 00:00:00

abstract：:The authors used different kinds of peripheral nerve grafts to reconstruct a terminal branch of the brachial plexus (the median nerve) gap of adult Sprague-Dawley rats, including fresh or frozen autografts and allografts from Norway rats. They also performed acellular allograft repopulation by autogenous Schwann cells...

journal_title：Restorative neurology and neuroscience

authors： Accioli-De-Vaconcellos ZA,Kassar-Duchossoy L,Mira JC

更新日期：1999-01-01 00:00:00

abstract：:Granule cells of the dentate gyrus can be selectively destroyed by intrahippocampal injections of colchicine. The present study evaluates the consequences of this selective neuronal destruction on the afferent axon terminals which have been deprived of their normal targets. The area of the neuropil in the dentate gyru...

journal_title：Restorative neurology and neuroscience

authors： Goldschmidt RB,Steward O

更新日期：1992-01-01 00:00:00

abstract：:Fetal cerebral cortical tissue was transplanted into an aspirated lesion cavity made in the sensorimotor cortex of adult rats. Ten weeks after grafting, outgrowing fibers from the graft were visualized by an anterograde tracing technique using Phaseolus vulgaris leucoagglutinin (PHA-L). It was demonstrated that the ef...

journal_title：Restorative neurology and neuroscience

authors： Senatorov VV,Nyakas C,Fulop Z

更新日期：1993-01-01 00:00:00

abstract：:The aim of this study was to gauge the possible sprouting of primary afferent fibers following dorsal rhizotomies using Fos-like immunoreactivity (Fos-LI) in order to label neurons activated by formalin injection into the rat forepaw. To assess the functional consequences of possible sprouting of fine diameter primary...

journal_title：Restorative neurology and neuroscience

authors： Abbadie C,Lombard MC,Morain F,Besson JM

更新日期：1994-01-01 00:00:00

abstract：PURPOSE:Aging is believed to affect epigenetic marking of brain DNA with 5-methylcytosine (5mC) and possibly via the 5mC to 5-hydroxymethylcytosine (5hmC) conversion by TET (ten-eleven translocation) enzymes. We investigated the impact of aging on hippocampal DNA 5-hydroxymethylation including in the sequence of aging-...

journal_title：Restorative neurology and neuroscience

authors： Chen H,Dzitoyeva S,Manev H

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:The present work compared the behavioral outcomes of ACCS therapy delivered either intravenously (i.v.) or intracerebroventricularly (i.c.v.) after penetrating ballistic-like brain injury (PBBI). Histological markers for neuroinflammation and neurodegeneration were employed to investigate the potential therapeu...

journal_title：Restorative neurology and neuroscience

authors： Deng-Bryant Y,Readnower RD,Leung LY,Cunningham TL,Shear DA,Tortella FC

更新日期：2015-01-01 00:00:00

abstract：:We have tested the capacity of several compounds with in vitro and/or in vivo antioxidant or antilipolytic activity to ameliorate locomotor function in cats subjected to static loading (i.e. compression) injury of the spinal cord. These include the synthetic glucocorticoid, methylprednisolone sodium succinate (MP), an...

journal_title：Restorative neurology and neuroscience

authors： Anderson DK

更新日期：1991-01-01 00:00:00

abstract：:Although neurotransmitter-based hypotheses still prevail current thinking about the mechanism of action of psychotropic drugs, recent insight into the pathophysiology of psychiatric disorders has unveiled a range of new therapeutic actions of the drugs used to treat those disorders. Especially antidepressants seem to ...

journal_title：Restorative neurology and neuroscience

authors： Paulzen M,Veselinovic T,Gründer G

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:A cerebral ischemic stroke involves mitochondrial dysfunction, motor deficits, and paralysis; and Danhong injection (DHI) might possess mitochondrial protection and functional recovery in a stroke subject through promoting expression of parkin, a ubiquitin ligase playing a key role in the regulation of prote...

journal_title：Restorative neurology and neuroscience

authors： Orgah JO,Ren J,Liu X,Orgah EA,Gao XM,Zhu Y

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Traumatic brain injury can result in lasting cognitive dysfunction due to degeneration of mature hippocampal neurons as well as the loss of immature neurons within the dentate gyrus. While endogenous neurogenesis affords a partial recovery of the immature neuron population, hippocampal neurogenesis may be en...

journal_title：Restorative neurology and neuroscience

authors： Sama DM,Carlson SW,Joseph B,Saenger S,Metzger F,Saatman KE

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:In brain-computer interfaces (BCIs), electrical brain signals during motor imagery are utilized as commands connecting the brain to a computer. To use BCI in patients with stroke, unique brain signal changes should be characterized during motor imagery process. This study aimed to examine the trial-dependent mo...

journal_title：Restorative neurology and neuroscience

authors： Lee M,Park CH,Im CH,Kim JH,Kwon GH,Kim L,Chang WH,Kim YH

更新日期：2015-08-26 00:00:00

abstract：PURPOSE:Contralateral primary sensori-motor cortex (SM1) activation by passive movement was investigated by functional MRI (fMRI) at the early stage of stroke, to determine whether SM1 activation can be used to predict the degree of motor recovery of the hemiplegic hand. METHODS:We studied 17 stroke patients who showe...

journal_title：Restorative neurology and neuroscience

authors： Jang SH,Kim YH,Chang Y,Han BS,Byun WM,Chang CH

更新日期：2004-01-01 00:00:00

abstract：PURPOSE:The aim of the present study was to explore the use of two-photon microscopy for investigating the therapeutic time window of methylprednisolone (MP) treatment after spinal cord injury (SCI). METHODS:Twenty-four YFP H-line mice were subjected to hemisection SCI and then divided into four groups. Group 1 receiv...

journal_title：Restorative neurology and neuroscience

authors： Zhang Y,Zhang L,Ji X,Pang M,Ju F,Zhang J,Li W,Zhang S,He Z,Gan WB,Tang P

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:This study investigated whether enrichment improves hindlimb movement following complete spinal cord transection and transplantation of olfactory ensheathing glia (OEG), with or without a Schwann cell (SC) bridge. METHODS:Motor activity was encouraged through provision of motor enrichment housing (MEH); a mult...

journal_title：Restorative neurology and neuroscience

authors： Moon LD,Leasure JL,Gage FH,Bunge MB

更新日期：2006-01-01 00:00:00

abstract：:Non-invasive brain stimulation techniques, such as repetitive transcranial magnetic stimulation (rTMS), can modify cortical excitability in a lasting fashion. The modification can be bi-directional in nature and holds considerable therapeutic promise for a number of neurological conditions. However, the effectiveness ...

journal_title：Restorative neurology and neuroscience

authors： Todd G,Ridding MC

更新日期：2010-01-01 00:00:00

abstract：PURPOSE:Bacopa monnieri (L.) WETTST. is extensively used in traditional Indian medicine as a nerve tonic. The neuropharmacological properties of bacopaside I, an important component from B. monnieri, have not been studied so far. The present study investigated the effects and possible mechanisms of bacopaside I in a ra...

journal_title：Restorative neurology and neuroscience

authors： Liu X,Yue R,Zhang J,Shan L,Wang R,Zhang W

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:The primary somatosensory cortex (S1) is somatotopically reorganized after limb amputation. The duration of the amputation, the intensity of phantom limb pain but also a multifactoral model of altered cerebral input have been discussed to be associated with cortical changes. Patients with finger amputation rare...

journal_title：Restorative neurology and neuroscience

authors： Oelschläger M,Pfannmöller J,Langner I,Lotze M

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The dopamine system plays a key role in motor learning and neuroplasticity. Several studies have studied the efficacy of dopaminergic drugs in enhancing motor recovery after stroke, but the effects are controversial. Although genetic variations in plasticity-related genes influence each individual's capacity...

journal_title：Restorative neurology and neuroscience

authors： Kim BR,Kim HY,Chun YI,Yun YM,Kim H,Choi DH,Lee J

更新日期：2016-11-22 00:00:00

abstract：:Traumatic brain and spinal cord injuries are severe burdens for the patients, their relatives, the health care providers and society as a whole. Recent data demonstrate the magnitude of the problem: It is mostly a disease of the young gen-eration (age 20-45 years) with mortality rates for severe traumatic brain injury...

journal_title：Restorative neurology and neuroscience

authors： Neugebauer E,Lefering R,Noth J

更新日期：1999-01-01 00:00:00

abstract：PURPOSE:Despite advances towards potential clinically viable therapies there has been only limited success in improving functional recovery following traumatic brain injury (TBI). In rats, exposure to an enriched environment (EE) improves learning and fosters motor skill development. Induced pluripotent stem cells (iPS...

journal_title：Restorative neurology and neuroscience

authors： Dunkerson J,Moritz KE,Young J,Pionk T,Fink K,Rossignol J,Dunbar G,Smith JS

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:Traumatic brain injury (TBI) -induced brain edema can be reduced by acute progesterone (PROG) treatment in young adult males and females, and in aged males. To extend these findings we tested these hypotheses: 1. Acute PROG treatment post-TBI will reduce cortical edema in aged females as much as in young adults...

journal_title：Restorative neurology and neuroscience

authors： Kasturi BS,Stein DG

更新日期：2009-01-01 00:00:00

abstract：:PURPOSE: Until recently, there has been a limited amount of research comparing functional and anatomical recovery following nerve injury. Previous studies emphasizing anatomical recovery (such as axonal number) have shown that testosterone promotes regeneration in crushed and transected nerves. The purpose of this stu...

journal_title：Restorative neurology and neuroscience

authors： Swallow RK,Leiser MR,Fink BE,Sauer C,Nicklous DM,Hoffman JR

更新日期：1999-01-01 00:00:00

abstract：:Since various studies, including multi-centre studies, investigating the effect of repetitive transcranial magnetic stimulation (rTMS) in depression have shown different results, it is now important to research, which symptoms of depression are most responsive to this kind of non-invasive brain stimulation. Furthermor...

journal_title：Restorative neurology and neuroscience

authors： Höppner J,Berger C,Walter U,Padberg F,Buchmann J,Herwig U,Domes G

更新日期：2010-01-01 00:00:00

abstract：PURPOSE:Freezing of gait (FOG) affects mobility and balance seriously. Few reports have investigated the effects of repetitive transcranial magnetic stimulation (rTMS) on FOG in Parkinson's disease (PD). We investigated the efficacy of high-frequency rTMS for the treatment of FOG in PD. METHODS:Seventeen patients diag...

journal_title：Restorative neurology and neuroscience

authors： Kim MS,Chang WH,Cho JW,Youn J,Kim YK,Kim SW,Kim YH

更新日期：2015-01-01 00:00:00

abstract：:PURPOSE: Nerve allografts are highly antigenic and, thus, require the continuous use of immunosuppressive drugs. FK 506 was found to pre-vent rejection successfully. However, clinically neurotoxic complications have been noted in the central and peripheral nervous system although an increased rate of axonal regenerati...

journal_title：Restorative neurology and neuroscience

authors： Fansa H,Keilhoff G,Horn T,Altmann S,Wolf G,Schneider W

更新日期：2000-01-01 00:00:00

abstract：:Vestibular habituation was studied in normal subjects and in patients with cerebellar disease using a stimulation paradigm proposed in this paper. Six caloric stimuli were repeated daily in the same ear during six days and electronystagmographic responses at the beginning and the end of that period were compared. The ...

journal_title：Restorative neurology and neuroscience

authors： Suarez H,Caffa C,Macadar O

更新日期：1992-01-01 00:00:00

abstract：:While the regenerating capacity of peripheral nerves has been the subject of intensive study, little is known about the regenerative capacity of the autonomic nervous system. Using an animal model, where the pupil diameter of the eye in the rat serves as a parameter of autonomic function, we studied whether systemic t...

journal_title：Restorative neurology and neuroscience

authors： Vandertop WP,de Vries WB,Notermans NC,Tulleken CA,Gispen WH

更新日期：1994-01-01 00:00:00

abstract：PURPOSE:Current models of intracerebral hematoma are difficult to use for neurotransplantation studies because of high mortality and important variations of morphology, size and location of blood deposits. We propose a modification of the autologous blood infusion technique in rats to reduce these limitations. METHODS...

journal_title：Restorative neurology and neuroscience

authors： Barth A,Guzman R,Andres RH,Mordasini P,Barth L,Widmer HR

更新日期：2007-01-01 00:00:00