Abstract:
:The monovalent lithium ion inhibits the enzyme myo-inositol-1-phosphatase at concentrations comparable to those which are useful in the treatment of manic depressive illness. However, dialyzed cortical homogenates from rats which have been fed diets containing lithium carbonate demonstrate increased myo-inositol-1-phosphate phosphatase activity. Over a 4-week period, there is an approximate doubling of the lithium-sensitive myo-inositol-1-phosphatase activity in the homogenate.
journal_name
Brain Resjournal_title
Brain researchauthors
Renshaw PF,Joseph NE,Leigh JS Jrdoi
10.1016/0006-8993(86)90245-3subject
Has Abstractpub_date
1986-08-20 00:00:00pages
401-4issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(86)90245-3journal_volume
380pub_type
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