Two months sodium nitrate supplementation alleviates testicular injury in streptozotocin-induced diabetic male rats.

abstract：:Expression of reelin, reelin receptors [apolipoprotein E receptor 2 (ApoER2) and very low density lipoprotein receptor (VldlR)] and the Disabled-1 (Dab1) protein was investigated in rat intestinal mucosa. Intestinal reelin and Dab1 mRNA levels were maximal in the early stages of life, reaching adult levels in 1-month-...

journal_title：Experimental physiology

authors： García-Miranda P,Peral MJ,Ilundain AA

更新日期：2010-04-01 00:00:00

abstract：:Hypoglossal nerve activity (HNA) controls the position and movements of the tongue. In persons with compromised upper airway anatomy, sleep-related hypotonia of the tongue and other pharyngeal muscles causes increased upper airway resistance, or total upper airway obstructions, thus disrupting both sleep and breathing...

journal_title：Experimental physiology

authors： Brandes IF,Stettner GM,Mörschel M,Kubin L,Dutschmann M

更新日期：2011-05-01 00:00:00

abstract：:Neural activation decreases cerebral deoxyhaemoglobin (HHb(C)) and increases oxyhaemoglobin concentration (O(2)Hb(C)). In contrast, patients who present with restricted cerebral blood flow, such as those suffering from cerebral ischaemia or Alzheimer's disease, and during the course of ageing the converse occurs, in t...

journal_title：Experimental physiology

authors： Miyazawa T,Horiuchi M,Ichikawa D,Sato K,Tanaka N,Bailey DM,Ogoh S

更新日期：2012-02-01 00:00:00

abstract：:Intracellular pH (pHi) was measured in left ventricular myocytes from hearts hypertrophied by constriction of the thoracic aorta. There was a continuous relation between an increase in heart-to-body weight ratio and a decrease in pHi (mean +/- S.D., 7.06 +/- 0.18 pH units in control hearts vs. 6.87 +/- 0.17 pH units i...

journal_title：Experimental physiology

authors： Wallis WR,Wu C,Sheridan DJ,Fry CH

更新日期：1997-01-01 00:00:00

abstract：:We have examined the surface ultrastructure and morphological characteristics of leucocytes obtained from control rats breathing air and rats made acutely hypoxic (breathing 6% O2, for 30 min). Striking ultrastructural and morphological changes occurred in the leucocytes of hypoxic rats. These changes included the app...

journal_title：Experimental physiology

authors： Mian R,Westwood D,Stanley P,Marshall JM,Coote JH

更新日期：1993-11-01 00:00:00

abstract：:We investigated the permeability of Cs+ and Na+ through various ion channels in rat atrial myocytes using the whole-cell voltage-clamp technique. With isotonic CsCl (140 mM) on both sides of the membrane and nominally [Ca2+]o-free conditions, depolarising clamp pulses induced an increase of outward currents which show...

journal_title：Experimental physiology

authors： Youm JB,Ho WK,Earm YE

更新日期：2000-03-01 00:00:00

abstract：:Changes in tension of slow motor units in the medial gastrocnemius muscle of the rat were measured and compared in three fatigue tests, each of 4 min duration. In one of these tests motor unit tetani were evoked by repeated trains of stimuli of the standard frequency, 40 Hz, while in other tests frequencies of 20 and ...

journal_title：Experimental physiology

authors： Celichowski J,Grottel K

更新日期：1995-11-01 00:00:00

abstract：:One of the most basic computational elements within a circuit is the synapse across which signals are transferred. Here we summarize some experimental strategies that allow the synaptic basis of circuit function to be studied through imaging. The two most promising approaches available currently are pHluorin-based rep...

journal_title：Experimental physiology

authors： Dreosti E,Lagnado L

更新日期：2011-01-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? What are the characteristics of the NK cell response following acute moderate-intensity aerobic exercise in prostate cancer survivors and is there a relationship between stress hormones and NK cell mobilization? What is the main finding and its importance? NK cel...

journal_title：Experimental physiology

authors： Hanson ED,Sakkal S,Que S,Cho E,Spielmann G,Kadife E,Violet JA,Battaglini CL,Stoner L,Bartlett DB,McConell GK,Hayes A

更新日期：2020-09-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Does the combination of methazolamide and theophylline reduce symptoms of acute mountain sickness (AMS) and improve aerobic performance in acute hypobaric hypoxia? What is the main finding and its importance? The oral combination of methazolamide (100 BID) and th...

journal_title：Experimental physiology

authors： Subudhi AW,Evero O,Reitinger J,Davis C,Gronewold J,Nichols AJ,Van-Houten SJ,Roach RC

更新日期：2021-01-01 00:00:00

abstract：:Tumour cell survival is intimately related to blood vessel function and so the tumour vasculature represents a novel target for cancer therapy. We have investigated a murine tumour model in which a metal clamp was used to occlude the vascular supply temporarily and then removed to allow reperfusion. This allows the st...

journal_title：Experimental physiology

authors： Parkins CS,Hill SA,Stratford MR,Dennis MF,Chaplin DJ

更新日期：1997-03-01 00:00:00

abstract：:The purpose of the present study was to investigate the effect of temperature on the rates of isometric force development and relaxation in electrically activated fresh and fatigued human adductor pollicis muscle. Following immersion of the lower arm for 20 min in water baths of four different temperatures, muscle tem...

journal_title：Experimental physiology

authors： de Ruiter CJ,Jones DA,Sargeant AJ,de Haan A

更新日期：1999-11-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Exercise for type 2 diabetes patients treated with insulin therapy involves the risk of hypoglycaemia. Dipeptidyl peptidase-4 (DPP-4) inhibitors can be effective in combination with exercise because they reduce the incidence of hypoglycaemia. We evaluated the eff...

journal_title：Experimental physiology

authors： Tanimura Y,Aoi W,Mizushima K,Higashimura Y,Naito Y

更新日期：2019-07-01 00:00:00

abstract：NEW FINDINGS:What is the topic of this review? We discuss tools available to access genome-wide data sets that harbour cell-specific, brain region-specific and tissue-specific information on exon usage for several species, including humans. In this Review, we demonstrate how to access this information in genome databas...

journal_title：Experimental physiology

authors： Lipscombe D,Pan JQ,Schorge S

更新日期：2015-12-01 00:00:00

abstract：NEW FINDINGS:What is the topic of this review? I focus on clinical aspects of uterine physiology, specifically, myometrial contractility. I bring together and contrast findings using physiological approaches and those using newer techniques, 'omics'. What advances does it highlight? Physiological studies have recently ...

journal_title：Experimental physiology

authors： Wray S

更新日期：2015-12-01 00:00:00

abstract：:This work was undertaken to study the effect of pectin feeding on the expression level, cellular localization and functional activity of monocarboxylate transporter 1 (MCT1) in the gastrointestinal tract of rats. The results indicated that MCT1 protein level was significantly increased along the entire length of the g...

journal_title：Experimental physiology

authors： Kirat D,Kondo K,Shimada R,Kato S

更新日期：2009-04-01 00:00:00

abstract：:The vasoregulatory role of nitric oxide (NO) and angiotensin II type 1 (AT(1)) receptors in the circulation of the submandibular gland (SMG) of rats was studied. The glandular blood flow was determined by means of laser Doppler flowmetry and rubidium isotope technique. The data obtained by these two methods correlated...

journal_title：Experimental physiology

authors： Vág J,Kerémi B,Hably C,Bartha J,Fazekas A

更新日期：2002-05-01 00:00:00

abstract：:The effects of microinjections of adenosine and an adenosine receptor antagonist into the rostral ventrolateral medulla (RVLM) on the cardiovascular changes associated with the defence reaction were investigated in anaesthetized rats. Responses to electrical and chemical stimulation in RVLM were determined in alpha-ch...

journal_title：Experimental physiology

authors： Thomas T,Spyer KM

更新日期：1996-01-01 00:00:00

abstract：:The properties of two types of calcium current (ICa(T) and ICa(L)) and their relationship with contraction were studied in isolated frog atrial trabeculae using the double mannitol gap technique. In Ringer solution containing TTX the calcium currents observed are similar to the ICa(T) and ICa(L) found in single frog a...

journal_title：Experimental physiology

authors： Badaoui A,Léoty C

更新日期：1994-09-01 00:00:00

abstract：:The effects of modification of the levels of endogenous plasma insulin on intestinal epithelial cell proliferation were investigated in rats maintained by total parenteral nutrition (TPN) using either a TPN diet that was high in glucose, or a low glucose (hypocaloric) TPN diet and in orally fed rats (normal and sham o...

journal_title：Experimental physiology

authors： Goodlad RA,Lee CY,Gilbey SG,Ghatei MA,Bloom SR

更新日期：1993-09-01 00:00:00

abstract：:Gastric motility was recorded from ferrets chronically prepared with an antral strain gauge. In fasted animals, antral motility showed cycles of activity and quiescence typical of the migrating motor complex (MMC) with a period of 44.7 +/- 6.1 min (n = 4). Anaesthesia with pentobarbitone sodium (50 mg/kg) disrupted th...

journal_title：Experimental physiology

authors： Grundy D

更新日期：1990-09-01 00:00:00

abstract：:The autonomic adjustments to exercise are mediated by central signals from the higher brain (central command) and by a peripheral reflex arising from working skeletal muscle (exercise pressor reflex), with further modulation provided by the arterial baroreflex. Although it is clear that central command, the exercise p...

journal_title：Experimental physiology

authors： Williamson JW,Fadel PJ,Mitchell JH

更新日期：2006-01-01 00:00:00

abstract：:Fluid and electrolyte movements across the ruminal epithelium of sheep were studied using the temporarily isolated rumen technique. The sheep were all subjected to the following treatments: (1) fed sheep (fed twice daily), after rumen emptying, received rumen contents from a fed sheep; (2) food-deprived sheep (two mea...

journal_title：Experimental physiology

authors： Holtenius K,Dahlborn K

更新日期：1990-01-01 00:00:00

abstract：NEW FINDINGS:What is the topic of this review? This review provides a comprehensive overview of Nox5 from basic biology to human disease and highlights unique features of this Nox isoform What advances does it highlight? Major advances in Nox5 biology relate to crystallization of the molecule and new insights into the ...

journal_title：Experimental physiology

authors： Touyz RM,Anagnostopoulou A,Rios F,Montezano AC,Camargo LL

更新日期：2019-05-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Exertional heat stroke is accompanied by a marked inflammatory response. In this study, we explored the time course of acute phase proteins during recovery from severe heat stress in mice and the potential role of skeletal muscles as their source. What is the mai...

journal_title：Experimental physiology

authors： Iwaniec J,Robinson GP,Garcia CK,Murray KO,de Carvalho L,Clanton TL,Laitano O

更新日期：2021-01-01 00:00:00

abstract：:The nucleus tractus solitarii (NTS) is a key central link in control of multiple homeostatic reflexes. A number of studies have demonstrated that exogenous and endogenous nitric oxide (NO) within NTS regulates visceral function, but further understanding of the role of NO in the NTS is hampered by the lack of informat...

journal_title：Experimental physiology

authors： Wang S,Paton JF,Kasparov S

更新日期：2007-03-01 00:00:00

abstract：:Recently attempts have been made to analyse blood pressure (BP) and renal sympathetic nerve activity (RSNA) to determine how patterns contained within them might reflect control by the autonomic nervous system. To date, these studies have primarily used coherence analysis of BP and RSNA in the frequency domain. Howeve...

journal_title：Experimental physiology

authors： Yang Z,Zhang T,Coote JH

更新日期：2002-07-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Should we use the high-frequency (HF) component of P-P interval as an index of cardiac parasympathetic nerve activity during moderate exercise? What is the main finding and its importance? The HF component of P-P interval variability remained even at a heart rate...

journal_title：Experimental physiology

authors： Takahashi M,Nakamoto T,Matsukawa K,Ishii K,Watanabe T,Sekikawa K,Hamada H

更新日期：2016-03-01 00:00:00

abstract：:The pathogenesis of the vasodilatation associated with liver cirrhosis is not fully understood, but it has recently been postulated that it may be related to an increase in nitric oxide production. The aim of this study was to compare the response of isolated aortic rings from normal and cirrhotic rats to two vasocons...

journal_title：Experimental physiology

authors： Van Obbergh L,Leonard V,Chen H,Xu D,Blaise G

更新日期：1995-07-01 00:00:00

abstract：:Contractile properties and fibre type composition of slow-twitch soleus muscles from spontaneously hypertensive rats (SHR) were compared with those from a control normotensive strain (Wistar-Kyoto, WKY). Male rats aged around 100 days were used, and muscle tension was recorded isometrically in vitro. Tetanic tension w...

journal_title：Experimental physiology

authors： Lewis DM,Levi AJ,Brooksby P,Jones JV

更新日期：1994-05-01 00:00:00