Permeability characteristics of monovalent cations in atrial myocytes of the rat heart.

abstract：NEW FINDINGS:What is the central question of this study? Could different hormonally active substances, including oestrogen receptor (ER) agonists, protect against oxidative brain damage and memory impairment induced by a single epileptic seizure in rats? If so, which signalling mechanisms are involved in their anti-inf...

journal_title：Experimental physiology

authors： Koyuncuoğlu T,Arabacı Tamer S,Erzik C,Karagöz A,Akakın D,Yüksel M,Yeğen BÇ

更新日期：2019-12-01 00:00:00

abstract：:Exercise induces a marked increase in interleukin-8 (IL-8) mRNA and protein expression within skeletal muscle fibres. Interleukin-8 belongs to a subfamily of CXC chemokines containing a Glu-Leu-Arg (ELR) motif. CXC chemokines with ELR motifs are potent angiogenic factors in vivo, and IL-8 has been shown to act as an a...

journal_title：Experimental physiology

authors： Frydelund-Larsen L,Penkowa M,Akerstrom T,Zankari A,Nielsen S,Pedersen BK

更新日期：2007-01-01 00:00:00

abstract：:The effects of muscle fatigue on the mechanical efficiency of muscle work performance were studied in situ, in stretch-shortening cycles that resembled physiological conditions. The experiments were performed on the medial gastrocnemius muscles of seven rats. To calculate efficiency, a simple Hill-type model was used,...

journal_title：Experimental physiology

authors： Ettema GJ

更新日期：1997-01-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? What are the ultrastructural changes of the caecal mucosa and the status of epithelial cellular apoptosis and oxidative reactions in lactating goats after prolonged feeding with a high-concentrate diet? What is the main finding and its importance? High-concentrat...

journal_title：Experimental physiology

authors： Tao S,Tian J,Cong R,Sun L,Duanmu Y,Dong H,Ni Y,Zhao R

更新日期：2015-03-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? What are the effects of a 2 week period of severe food restriction on vascular reactivity of resistance arteries and on cardiac structure and function? What is the main finding and its importance? This study showed, for the first time, that a 2 week period of sev...

journal_title：Experimental physiology

authors： Almeida JFQ,Shults N,de Souza AMA,Ji H,Wu X,Woods J,Sandberg K

更新日期：2020-07-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Glucose is the dominant energy source for the brain. However, little is known about how glucose metabolism impacts the coordination of network activity in the brain in healthy adults. What is the main finding and its importance? We demonstrate that both alpha osc...

journal_title：Experimental physiology

authors： Walker CP,Buse J,Frohlich F

更新日期：2021-01-28 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? The aim was to determine the effect of mid-portion Achilles tendinopathy (MAT) on free Achilles tendon three-dimensional morphology and volume at rest and under load in people with unilateral MAT. What is the main finding and its importance? Tendinopathic tendon ...

journal_title：Experimental physiology

authors： Nuri L,Obst SJ,Newsham-West R,Barrett RS

更新日期：2018-03-01 00:00:00

abstract：:The cardiovascular response to isometric exercise is governed by both central and peripheral mechanisms. Both metabolic and mechanical stresses on the exercising skeletal muscle produce cardiovascular change, yet it is often overlooked that the afferent signal arising from the muscle can be modified by factors other t...

journal_title：Experimental physiology

authors： Fisher JP,White MJ

更新日期：2004-11-01 00:00:00

abstract：:This study examined whether left ventricular function was reduced during 3 h of semi-recumbent ergometer cycling at 70% of maximal oxygen uptake while preload to the heart was maintained via saline infusion. Indices of left ventricular systolic function (end-systolic blood pressure-volume relationship, SBP/ESV) and di...

journal_title：Experimental physiology

authors： Dawson EA,Shave R,Whyte G,Ball D,Selmer C,Jans Ø,Secher NH,George KP

更新日期：2007-03-01 00:00:00

abstract：UNLABELLED:The modulation of activity of the upper airway dilator and respiratory muscles plays a key role in the regulation of ventilation, but little is known about the link between their neuromuscular activation processes in vivo. This study investigated genioglossus and diaphragm responses to transcranial magnetic ...

journal_title：Experimental physiology

authors： Wang W,Similowski T,Sériès F

更新日期：2007-07-01 00:00:00

abstract：:In quiescent papillary muscles isolated from hearts of rats with streptozotocin-induced diabetes resting intracellular sodium activity (aiNa) was about 56% greater than in muscles from controls. An intracellular acid load induced by the NH4+ method caused a rise in aiNa whose maximum amplitude was similar in both grou...

journal_title：Experimental physiology

authors： Lagadic-Gossmann D,Feuvray D

更新日期：1991-01-01 00:00:00

abstract：:Beneficial effects of exercise training on the vasculature have been consistently reported in subjects with cardiovascular risk factors or disease, whereas studies in apparently healthy subjects have been less uniform. In this review, we examine evidence pertaining to the impact of exercise training on conduit and res...

journal_title：Experimental physiology

authors： Green DJ,Spence A,Halliwill JR,Cable NT,Thijssen DH

更新日期：2011-02-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Clinical studies suggest that obesity 'protects' against osteoporosis. However, these studies used only bone densitometry and assessed only one bone site, which is insufficient to enable conclusions to be drawn about the response of the whole skeleton. Furthermor...

journal_title：Experimental physiology

authors： Lacerda DR,Serakides R,de Melo Ocarino N,Ferreira AV,Moraes MM,Boeloni JN,Silva JF,de Oliveira MC,de Barcellos LA,Rodrigues LO,Soares DD

更新日期：2015-01-01 00:00:00

abstract：:Experiments were performed to investigate, in the normal and acutely inflamed rabbit knee joint, the role of prostaglandins in the regulation of joint blood flow, measured by laser Doppler flowmetry, as well as their modulation of sympathetic vasoconstriction. Close intra-arterial injection of prostaglandin E2 (PGE2) ...

journal_title：Experimental physiology

authors： Najafipour H,Ferrell WR

更新日期：1994-01-01 00:00:00

abstract：:The purpose of the present study was to investigate the effect of temperature on the rates of isometric force development and relaxation in electrically activated fresh and fatigued human adductor pollicis muscle. Following immersion of the lower arm for 20 min in water baths of four different temperatures, muscle tem...

journal_title：Experimental physiology

authors： de Ruiter CJ,Jones DA,Sargeant AJ,de Haan A

更新日期：1999-11-01 00:00:00

abstract：:Hypertension caused by chronic infusion of angiotensin II (Ang II) in experimental animals is dependent, in part, on increased activity of the sympathetic nervous system. This chronic sympathoexcitatory response is amplified by a high-salt diet, suggesting an interaction of circulating Ang II and dietary salt on sympa...

journal_title：Experimental physiology

authors： Osborn JW,Hendel MD,Collister JP,Ariza-Guzman PA,Fink GD

更新日期：2012-01-01 00:00:00

abstract：NEW FINDINGS:What is the topic of this review? In this review, we examine the evidence for control mechanisms underlying exercise hyperpnoea, giving attention to the feedback from thin-fibre skeletal muscle afferents, and highlight the frequently conflicting findings and difficulties encountered by researchers using a ...

journal_title：Experimental physiology

authors： Bruce RM,Jolley C,White MJ

更新日期：2019-11-01 00:00:00

abstract：:The role of bicarbonate as a hydrogen ion buffer has been investigated using the fluorescent dye BCECF in individual rat cerebellar, hippocampal and neocortical neurones maintained in culture. The steady-state intracellular pH (pHi) was estimated to be 7.07 +/- 0.05 (n = 22) in CO2-HCO3(-)-buffered media. Buffering po...

journal_title：Experimental physiology

authors： Amos BJ,Pocock G,Richards CD

更新日期：1996-07-01 00:00:00

abstract：:Therapeutic angiogenesis/vasculogenesis holds promise for the cure of ischaemic disease. The approach postulates the manipulation of spontaneous healing response by supplementation of growth factors or transplantation of vascular progenitor cells. These supplements are intended to foster the formation of arterial coll...

journal_title：Experimental physiology

authors： Madeddu P

更新日期：2005-05-01 00:00:00

abstract：:Age is a primary risk factor for cardiovascular disease, and this is an increasingly important public health concern because of an increase in the absolute number and proportion of the population at an older age in many countries. A key component of cardiovascular ageing is reduced function of the vascular endothelium...

journal_title：Experimental physiology

authors： Gates PE,Strain WD,Shore AC

更新日期：2009-03-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Do GABA receptors play any role at the neuromuscular junction? What is the main finding and its importance? In the presence of either ionotropic or metabotropic GABA receptor antagonists, diaphragm muscle force production elicited by stimulating the motor nerve a...

journal_title：Experimental physiology

authors： Lenina O,Petrov K,Kovyazina I,Malomouzh A

更新日期：2019-07-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Research has reported that some sensory input, such as auditory and olfactory input, can affect subliminal visual processing. However, it is important to address whether tactile input, another form of elementary sensory input, could influence the interocular riva...

journal_title：Experimental physiology

authors： Lang Y,Gao M,Huang Q,Liu Z,Wu L,Tang R

更新日期：2019-11-01 00:00:00

abstract：:Tumour cell survival is intimately related to blood vessel function and so the tumour vasculature represents a novel target for cancer therapy. We have investigated a murine tumour model in which a metal clamp was used to occlude the vascular supply temporarily and then removed to allow reperfusion. This allows the st...

journal_title：Experimental physiology

authors： Parkins CS,Hill SA,Stratford MR,Dennis MF,Chaplin DJ

更新日期：1997-03-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? We present a new non-invasive medical technology, the inspired sine-wave technique, which involves inhalation of sinusoidally fluctuating concentrations of a tracer gas. The technique requires only passive patient cooperation and can monitor different cardiorespi...

journal_title：Experimental physiology

authors： Bruce RM,Phan PA,Pacpaco E,Rahman NM,Farmery AD

更新日期：2018-05-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? To what extent focal abdominal aortic aneurysmal (AAA) disease is associated with systemic remodelling of the vascular tree remains unknown. The present study examined whether anatomical differences exist between distances of the intervisceral artery origins and ...

journal_title：Experimental physiology

authors： Bailey DM,Evans TG,Thomas KG,White RD,Twine CP,Lewis MH,Williams IM

更新日期：2016-08-01 00:00:00

abstract：:The contractile regulation of neonatal smooth muscle was studied in rat neonatal portal vein. Strips of beta-escin-permeabilized portal vein from 3- to 5-day-old rats and 5- to 6-week-old rats were mounted on a 'bubble chamber' in calcium solutions buffered with 10 mM EGTA. Although the overall tension development was...

journal_title：Experimental physiology

authors： Bruce L,Nixon GF

更新日期：1997-11-01 00:00:00

abstract：:This work was undertaken to study the effect of pectin feeding on the expression level, cellular localization and functional activity of monocarboxylate transporter 1 (MCT1) in the gastrointestinal tract of rats. The results indicated that MCT1 protein level was significantly increased along the entire length of the g...

journal_title：Experimental physiology

authors： Kirat D,Kondo K,Shimada R,Kato S

更新日期：2009-04-01 00:00:00

abstract：:A considerable body of evidence indicates that the intracellular chloride concentration ([Cl-]i) is an important regulatory signal in epithelial ion transport. [Cl-]i regulates the open channel probability of sodium and chloride channels, the rate of chloride channel recycling to the apical membrane, cell volume homeo...

journal_title：Experimental physiology

authors： Treharne KJ,Crawford RM,Mehta A

更新日期：2006-01-01 00:00:00

abstract：:We tested the hypothesis that, among conditions of matched contractile work, shorter contraction durations and greater muscle fibre recruitment result in augmented skeletal muscle blood flow and oxygen consumption ( ) during steady-state exercise in humans. To do so, we measured forearm blood flow (FBF; Doppler ultras...

journal_title：Experimental physiology

authors： Richards JC,Crecelius AR,Kirby BS,Larson DG,Dinenno FA

更新日期：2012-06-01 00:00:00

abstract：:The effects on vasopressin and cortisol secretion of centrally and peripherally administered cholecystokinin octapeptide (CCK) were investigated in conscious prepubertal pigs. Injection of 1.3 micrograms CCK into the lateral cerebral ventricle resulted in a sustained increase in plasma vasopressin after a latency of 5...

journal_title：Experimental physiology

authors： Parrott RF,Ebenezer IS,Baldwin BA,Forsling ML

更新日期：1991-07-01 00:00:00