Abstract:
:In quiescent papillary muscles isolated from hearts of rats with streptozotocin-induced diabetes resting intracellular sodium activity (aiNa) was about 56% greater than in muscles from controls. An intracellular acid load induced by the NH4+ method caused a rise in aiNa whose maximum amplitude was similar in both groups of muscles. However, the half-time to maximum amplitude was increased by about 56% in diabetic muscles. These results are consistent with a diabetes-induced decrease in the activity of the sarcolemmal Na(+)-H+ exchange.
journal_name
Exp Physioljournal_title
Experimental physiologyauthors
Lagadic-Gossmann D,Feuvray Ddoi
10.1113/expphysiol.1991.sp003478subject
Has Abstractpub_date
1991-01-01 00:00:00pages
147-9issue
1eissn
0958-0670issn
1469-445Xjournal_volume
76pub_type
杂志文章abstract::It is unclear whether measurement of limb or conduit artery blood flow during recovery from exercise provides an accurate representation of flow to the muscle capillaries where gas exchange occurs. To investigate this, we: (a) examined the kinetic responses of femoral artery blood flow (QFA), estimated muscle capillar...
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journal_title:Experimental physiology
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journal_title:Experimental physiology
pub_type: 临床试验,杂志文章
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