Effect of temperature on growth of guanidine-resistant mutants of poliovirus.

Abstract:

:Guanidine-resistant (gr) mutants of poliovirus were previously categorized into four groups by electrophoretic properties and peptide maps of nonstructural virus protein 2C. Growth of mutants in the presence of guanidine depends upon temperature of incubation. The four groups of gr variants respond differently to temperature when guanidine is included in the culture medium. The data suggest clustering of gr mutations at several sites in the guanidine locus.

journal_name

Can J Microbiol

authors

Tershak DR

doi

10.1139/m85-220

subject

Has Abstract

pub_date

1985-12-01 00:00:00

pages

1166-8

issue

12

eissn

0008-4166

issn

1480-3275

journal_volume

31

pub_type

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