Corrigendum to "A North American perspective of content and quality of websites in the English language on childhood-onset lupus erythematosus".

abstract：BACKGROUND:Many studies in adult patients with systemic lupus erythematosus (SLE) have demonstrated that myocardial dysfunction was significantly associated with enhanced disease activity. However, similar studies in paediatric patients with SLE are limited. The aim of this study was to evaluate the role of speckle tra...

journal_title：Lupus

authors： Emara M,Hafez MA,El-Bendary A,Razaky OE

更新日期：2020-10-01 00:00:00

abstract：:Results for lupus anticoagulant (LA) are expressed as ratio of patient-to-normal clotting times (LA-ratio) according to the equation LA-ratio = (Patient(Clotting time)/Normal(Clotting time)). However, numerical results vary according to the method used for testing, thus making difficult the between-method and between-...

journal_title：Lupus

authors： Tripodi A,Chantarangkul V,Pengo V

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Cardiomyopathy in systemic lupus erythematosus (SLE) may be secondary to myocardial inflammation (i.e. myocarditis) or to systemic complications such as hypertension. Symptomatic left ventricular dysfunction is the most common clinical presentation of cardiomyopathy and is potentially life threatening. Ident...

journal_title：Lupus

authors： Appenzeller S,Pineau CA,Clarke AE

更新日期：2011-08-01 00:00:00

abstract：:Renal involvement is one of the main complications of systemic lupus erythematosus, causing a significant impact on patients' morbidity and mortality. Renal biopsy is still the gold standard of diagnosis, but it has many limitations. In this sense, several recent studies aim to identify biomarkers that not only predic...

journal_title：Lupus

authors： Gasparin AA,Pamplona Bueno de Andrade N,Hax V,Tres GL,Veronese FV,Monticielo OA

更新日期：2019-03-01 00:00:00

abstract：:Objectives Avascular necrosis (AVN) is one of the most common causes of organ damage in patients with systemic lupus erythematosus (SLE) and often causes serious physical disability. The aims of this study were to investigate clinical risk factors associated with symptomatic AVN and to analyze their synergistic effect...

journal_title：Lupus

authors： Kwon HH,Bang SY,Won S,Park Y,Yi JH,Joo YB,Lee HS,Bae SC

更新日期：2018-09-01 00:00:00

abstract：:The importance of the immunomodulatory effects of vitamin D has recently been associated with autoimmune and chronic inflammatory diseases. Vitamin D deficiency has been linked to the development of autoimmune conditions. Antiphospholipid syndrome is an autoimmune disease characterized by thrombotic events and obstetr...

journal_title：Lupus

authors： García-Carrasco M,Jiménez-Herrera EA,Gálvez-Romero JL,Mendoza-Pinto C,Méndez-Martínez S,Etchegaray-Morales I,Munguía-Realpozo P,Vázquez de Lara-Cisneros L,Santa Cruz FJ,Cervera R

更新日期：2018-12-01 00:00:00

abstract：:A dose-dependent combination of environmental exposures, estrogenic hormones and genetic predisposition is thought to be required for lupus to develop and flare, but how the environment modifies the immune system in genetically predisposed people is unclear. Current evidence indicates that environmental agents that in...

journal_title：Lupus

authors： Somers EC,Richardson BC

更新日期：2014-05-01 00:00:00

abstract：:Proteinuria is the hallmark of clinical manifestation of disease activity in lupus nephritis (LN) patients, which arises from direct or indirect podocyte injury. This study is to explore the relationship between intrarenal T cell infiltration and podocyte injury in lupus nephritis (LN), and to understand the potential...

journal_title：Lupus

authors： Ma R,Jiang W,Li Z,Sun Y,Wei Z

更新日期：2016-12-01 00:00:00

abstract：:Obstetric antiphospholipid syndrome (APS) remains a clinical challenge for practitioners, with several controversial points that have not been answered so far. This Obstetric APS Task Force met on the 16th International Congress on Antiphospholipid Antibodies in Manchester, England, to discuss about treatment, diagnos...

journal_title：Lupus

authors： de Jesús GR,Benson AE,Chighizola CB,Sciascia S,Branch DW

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Pregnancies in women with systemic lupus erythematosus (SLE) and lupus nephritis are considered high-risk due to high rates of maternal and fetal complications. However, there has not been a formal analysis addressing the issue of maternal deaths in these women. The aim of this study was to pe...

journal_title：Lupus

authors： Ritchie J,Smyth A,Tower C,Helbert M,Venning M,Garovic V

更新日期：2012-04-01 00:00:00

abstract：:Designing successful randomized controlled trials (RCTs) in systemic lupus erythematosus (SLE) poses many challenges. It remains difficult to correlate alterations in biologic markers with clinical outcome, especially when signs and symptoms are intermittent and broadly variable between patients. Disease activity indi...

journal_title：Lupus

authors： Strand V

更新日期：2004-01-01 00:00:00

abstract：:The objective of this study was to identify risk factors associated with flare during pregnancy in women with systemic lupus erythematosus (SLE). We performed a retrospective analysis of pregnant women with SLE in a referral hospital. Flare was considered according to predetermined definitions. We analyzed 15 clinical...

journal_title：Lupus

authors： Saavedra MA,Sánchez A,Morales S,Navarro-Zarza JE,Ángeles U,Jara LJ

更新日期：2015-02-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder that can have many cutaneous manifestations including malar rash, discoid rash or oral ulcer. Isolated unilateral involvement of face is uncommon in SLE. It lacks typical clinical features of LE, and may impose a diagnostic challenge for clinicians. H...

journal_title：Lupus

authors： Ha DL,Lee GW,Shin K,Kim HS,Ko HC,Kim BS,Kim MB

更新日期：2020-12-01 00:00:00

abstract：:Up to 80% of patients with systemic lupus erythematosus (SLE) are treated with nonsteroidal anti-inflammatory drugs (NSAID) for musculoskeletal symptoms, serositis and headache. This survey reviews the literature on non-selective and selective inhibitors of cyclooxygenases, with an emphasis on the efficacy and safety ...

journal_title：Lupus

authors： Ostensen M,Villiger PM

更新日期：2000-01-01 00:00:00

abstract：:Glycans (sugars or carbohydrates) are predominant surface components of cells such as erythrocytes, immune cells and microorganisms. As such, they give rise to high levels of anti-glycan antibodies of all classes. Antibodies to certain defined mono, di and oligosaccharides that are common in bacterial, fungal and para...

journal_title：Lupus

authors： Dotan N,Altstock RT,Schwarz M,Dukler A

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between antimalarials (AM) and elevated muscle enzymes in systemic lupus erythematosus (SLE). PATIENTSMETHODS:325 lupus patients with abnormal creatine phosphokinase (CPK) for at least two consecutive clinic visits were enrolled; 54 patients on statins/fibrates (n = 43) and/or...

journal_title：Lupus

authors： Tselios K,Gladman DD,Su J,Urowitz MB

更新日期：2016-04-01 00:00:00

abstract：:SLE is an autoimmune and polygenic disorder characterized by an accumulation and deposition of immune complexes. Several studies have indicated differential impact of FcgammaR polymorphism genotypes in different ethnic groups studied. The Fc receptor for IgG class IIA gene (FcgammaRIIA) occurs in two allelic forms. Th...

journal_title：Lupus

authors： Yap SN,Phipps ME,Manivasagar M,Tan SY,Bosco JJ

更新日期：1999-01-01 00:00:00

abstract：:This prospective multicentric register was initiated by the European Forum of Antiphospholipid Antibodies (APL) in 2003 after approval by local ethic committees. This register allows the investigation of infants after written informed parental consent. It collects mothers' clinical pattern of antiphospholipid syndrome...

journal_title：Lupus

authors： Boffa MC,Aurousseau MH,Lachassinne E,Dauphin H,Fain O,Le Toumelin P,Uzan M,Piette JC,Derenne S,Boinot C,Avcin T,Motta M,Faden D,Tincani A

更新日期：2004-01-01 00:00:00

abstract：:Introduction White matter hyperintense (WMHI) lesions are the most common finding in magnetic resonance imaging (MRI) of the brain in patients with systemic lupus erythematosus (SLE). Objective The objective of this article is to determine the clinical factors associated with an increase in WMHI lesion load among SLE ...

journal_title：Lupus

authors： Shaharir SS,Osman SS,Md Rani SA,Sakthiswary R,Said MSM

更新日期：2018-01-01 00:00:00

abstract：:Anti-phospholipid antibodies are common in patients in the Hopkins' Lupus Cohort: 47% have anti-cardiolipin, 32.5% anti-beta(2)-glycoprotein I and 26% lupus anticoagulant (by dRVVT confirmatory testing). Systemic lupus erythematosus patients with the lupus anticoagulant at baseline have a 50% chance of a deep venous t...

journal_title：Lupus

authors： Petri M

更新日期：2010-04-01 00:00:00

abstract：:We report three cases of severe haemorrhagic rupture of luteal ovarian cyst requiring surgical haemostasis in young women treated with long-term oral anticoagulation for antiphospholipid syndrome (APS) who used no contraception. At the time of bleeding, the international normalized ratios were 3.78, 4.24, and 7.11. An...

journal_title：Lupus

authors： Crétel E,Cacoub P,Huong DL,Gompel A,Amoura Z,Piette JC

更新日期：1999-01-01 00:00:00

abstract：:Thymus-derived CD4(+)CD25(high)Foxp3(+) T-regulatory cells (Tregs) have an important role in the mechanisms of peripheral immune tolerance and in the prevention of pathogenic autoimmunity through the suppression of proliferation and production of pro-inflammatory cytokines in effector immune cells. Some studies have s...

journal_title：Lupus

authors： La Cava A

更新日期：2008-05-01 00:00:00

abstract：:The potential of oral treatment with AVEMAR (AVEMAR), a new benzoquinone-containing fermentation product of wheat germ, on features of experimental systemic lupus erythematosus (SLE) in naive mice, induced by idiotypic manipulation, was studied. We assessed the effect of AVEMAR on the profile of autoantibody productio...

journal_title：Lupus

authors： Ehrenfeld M,Blank M,Shoenfeld Y,Hidvegi M

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Antibodies to M-type phospholipase A2 receptor (a-PLA2R) have been identified in most patients with idiopathic membranous nephropathy, but the prevalence in membranous lupus nephritis (MLN) is still unclear. The objective of this study was to assess the prevalence of a-PLA2R antibodies in a large cohort of p...

journal_title：Lupus

authors： Garcia-Vives E,Solé C,Moliné T,Alvarez-Rios AM,Vidal M,Agraz I,Ordi-Ros J,Cortés-Hernández J

更新日期：2019-03-01 00:00:00

abstract：:With the use of low-dose heparin, fetal survival of aPL pregnancies is 70-80%, but prematurity and intrauterine growth restriction are common. It is likely, but not proven, that dysregulated placental coagulation and resultant vasculopathy are the cause of fetal loss. Details of dysregulated coagulation remain to be d...

journal_title：Lupus

authors： Lockshin MD

更新日期：1998-01-01 00:00:00

abstract：:There is an increasing body of literature suggesting the efficacy and tolerability of mycophenolate mofetil (MMF) for the treatment of lupus nephritis. The rationale for its use is based upon its successful profile as an immunosuppressive agent for prevention of allograft rejection, as well as studies in murine models...

journal_title：Lupus

authors： Ginzler EM,Aranow C

更新日期：2005-01-01 00:00:00

abstract：:Vaccination has been perhaps the most important achievement in medicine of the last century. A hoard of infectious diseases that used to claim the lives of many, especially children, have been prevented and some even eradicated. However, it is possible that within this gift there is hidden a 'Trojan Horse'. During the...

journal_title：Lupus

authors： Aron-Maor A,Shoenfeld Y

更新日期：2001-01-01 00:00:00

abstract：:The acute clinical syndrome of toxic epidermal necrolysis (TEN) is currently thought to be a distinct clinical-pathological entity typically resulting from drug hypersensitivity. We describe an adult woman who experienced a fulminate pattern of apoptotic epidermal cell injury following tanning bed exposure while takin...

journal_title：Lupus

authors： Ting W,Stone MS,Racila D,Scofield RH,Sontheimer RD

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Ferritin is an iron storage protein considered also as an acute phase reactant with high levels in various inflammatory conditions. Recently, a plausible role for ferritin in the pathogenesis of immune-mediated and especially autoimmune diseases has been suggested. However, the link between ferritin and the ...

journal_title：Lupus

authors： Agmon-Levin N,Rosário C,Katz BS,Zandman-Goddard G,Meroni P,Cervera R,Stojanovich L,Blank M,Pierangeli S,Praprotnik S,Meis Ed,Seguro LP,Ruffatti A,Pengo V,Tincani A,Doria A,Shoenfeld Y

更新日期：2013-11-01 00:00:00

abstract：:Lupus nephritis is an important cause of morbidity and mortality in patients with systemic lupus erythematosus. Traditional outcome criteria such as doubling of serum creatinine, end-stage renal disease and death have been used in controlled therapeutic trials, but are limited by their low incidence and the extended p...

journal_title：Lupus

authors： Boumpas DT,Balow JE

更新日期：1998-01-01 00:00:00