European register of babies born to mothers with antiphospholipid syndrome.

Abstract:

:This prospective multicentric register was initiated by the European Forum of Antiphospholipid Antibodies (APL) in 2003 after approval by local ethic committees. This register allows the investigation of infants after written informed parental consent. It collects mothers' clinical pattern of antiphospholipid syndrome (APS), course and outcome of pregnancy, treatment and immunological status. For the babies, clinical and immunological examinations are performed at birth; neurodevelopmental conditions followed up to five years. A re-evaluation of lupus anticoagulant (LA), anticardiolipin (ACL) or other antibodies will be done if they are positive at birth to follow their kinetics. A descriptive and a case control study of babies with versus without APL at birth will be possible after the inclusion of 300 cases.

journal_name

Lupus

journal_title

Lupus

authors

Boffa MC,Aurousseau MH,Lachassinne E,Dauphin H,Fain O,Le Toumelin P,Uzan M,Piette JC,Derenne S,Boinot C,Avcin T,Motta M,Faden D,Tincani A

doi

10.1191/0961203304lu1089oa

subject

Has Abstract

pub_date

2004-01-01 00:00:00

pages

713-7

issue

9

eissn

0961-2033

issn

1477-0962

journal_volume

13

pub_type

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