Abstract:
:Thrombosis in the presence of persistently positive tests for antiphospholipid antibodies is termed thrombotic antiphospholipid syndrome (APS). At present, 'standard' secondary thromboprophylaxis in thrombotic APS is treatment with moderate intensity oral anticoagulants for life after a first venous thrombosis and with high intensity oral anticoagulation after non-embolic ischaemic stroke. These recommendations differ from those applied in the general population, where a restricted period of anticoagulation is common practice after venous thrombosis and antiplatelet drugs are the first choice after ischaemic stroke. From an extensive literature review we conclude that the available data are insufficient to apply a different strategy for secondary thromboprophylaxis in patients with thrombotic APS than the one that holds for the general population.
journal_name
Lupusjournal_title
Lupusauthors
Derksen RH,de Groot PGdoi
10.1177/0961203309361483subject
Has Abstractpub_date
2010-04-01 00:00:00pages
470-4issue
4eissn
0961-2033issn
1477-0962pii
19/4/470journal_volume
19pub_type
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