Risk-attitude and patient treatment preferences.

abstract：:The objective of this article was to evaluate whether serum uric acid (SUA) correlates with arterial stiffness and inflammation markers in a cohort of women with systemic lupus erythematosus (SLE) without overt atherosclerotic cardiovascular diseases, who attended a community hospital. One hundred and two women with S...

journal_title：Lupus

authors： Sabio JM,Vargas-Hitos JA,Mediavilla JD,Navarrete-Navarrete N,Zamora-Posadas M,Pérez-Vicente S,Hidalgo-Tenorio C,Díaz-Chamorro A,Jáimez L,Jiménez-Alonso J,Grupo Lupus Virgen de las Nieves.

更新日期：2010-04-01 00:00:00

abstract：:Progressive multifocal leukoencephalopathy (PML) is a rare, deadly demyelinating disease of the central nervous system, which is caused by a reactivation of the DNA polyomavirus JC and occurs in immunosuppressed individuals. So far, only 25 cases have been described in patients with SLE and none survived without antiv...

journal_title：Lupus

authors： Nived O,Bengtsson AA,Jönsen A,Sturfelt G

更新日期：2008-11-01 00:00:00

abstract：:We describe a patient with rheumatoid arthritis (RA) whose sera contained a high titre of an antibody targeting cytoplasmic ribosomal P proteins (anti-P). This association preceded by 6 years the development of serological and clinical manifestations of systemic lupus erythematosus (SLE). The clinical significance of ...

journal_title：Lupus

authors： Hamasaki K,Mimura T,Kanda H,Morino N,Yazaki Y,Nojima Y

更新日期：1997-01-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is an autoimmune disease with chronic systemic inflammation. Oxidative stress may play a role in the pathogenesis of SLE. An increase in free radicals or an impaired antioxidant defense system in SLE causes oxidative stress. Therefore, oxidative damage plays an important role in the ...

journal_title：Lupus

authors： Zaieni SH,Derakhshan Z,Sariri R

更新日期：2015-11-01 00:00:00

abstract：:We report the occurrence of visceral leishmaniasis in three patients coming from the northern part of Italy treated with immunosuppressive drugs for different rheumatic conditions. This paper highlights the importance of adequate work-up in those patients presenting with serious clinical manifestations that can compli...

journal_title：Lupus

authors： Castellino G,Govoni M,Lo Monaco A,Montecucco C,Colombo F,Trotta F

更新日期：2004-01-01 00:00:00

abstract：:The objective of this study was to assess the prevalence, clinical, histological and immunological characteristics, and the long-term outcome of polymyositis- (PM) and dermatomyositis- (DM) associated lung disease, and to define subgroups of lung-associated inflammatory myopathies. This retrospective study included 81...

journal_title：Lupus

authors： Selva-O'Callaghan A,Labrador-Horrillo M,Muñoz-Gall X,Martínez-Gomez X,Majó-Masferrer J,Solans-Laque R,Simeon-Aznar CP,Morell-Brotard F,Vilardell-Tarrés M

更新日期：2005-01-01 00:00:00

abstract：:Objective People affected by chronic rheumatic conditions, such as systemic lupus erythematosus (SLE), frequently rely on the Internet and search engines to look for terms related to their disease and its possible causes, symptoms and treatments. 'Infodemiology' and 'infoveillance' are two recent terms created to desc...

journal_title：Lupus

authors： Radin M,Sciascia S

更新日期：2017-07-01 00:00:00

abstract：:The objective of this study was to assess the incidence and risk factors of infections in 200 SLE outpatients. All outpatients with active or inactive SLE without infections in the previous month were included. They were assessed every 3 months. Major infections were those requiring hospitalization and parental antibi...

journal_title：Lupus

authors： Zonana-Nacach A,Camargo-Coronel A,Yañez P,Sánchez L,Jimenez-Balderas FJ,Fraga A

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:For patients with chronic illnesses the global burden of illness is a crucial health measure hitherto neglected in research studies and clinical practice. We tested the application and validity of PRISM (Pictorial Representation of Illness and Self-Measure), a novel visual method for assessing the burden of i...

journal_title：Lupus

authors： Büchi S,Villiger P,Kauer Y,Klaghofer R,Sensky T,Stoll T

更新日期：2000-01-01 00:00:00

abstract：:Multiple sources were used to identify 325 systemic lupus erythematosus (SLE) patients within the city of Oslo during 1999-2009 who met ≥ 4 of the American College of Rheumatology (ACR) criteria. The survival, standard mortality rate (SMR), years of potential life loss before 60 years of age (YPLL60) and causes of dea...

journal_title：Lupus

authors： Lerang K,Gilboe IM,Steinar Thelle D,Gran JT

更新日期：2014-12-01 00:00:00

abstract：:Mycobacterial infections can cause a variety of different manifestations. The increasing incidence of these infections worldwide brought another medical dilemma: immunological manifestations characterized by the presence of many autoantibodies and concomitant presence of autoimmune diseases. The burden of tuberculosis...

journal_title：Lupus

authors： Machado Ribeiro F,Goldenberg T

更新日期：2015-04-01 00:00:00

abstract：:Cytomegalovirus (CMV) is particularly dangerous in systemic lupus erythematosus (SLE), being a problem both for the differential diagnosis with disease flare and for the management of SLE flare with immunosuppressive drugs. We report on four cases of SLE with concomitant CMV infection, having some common clinical and ...

journal_title：Lupus

authors： Sebastiani GD,Iuliano A,Canofari C,Bracci M

更新日期：2019-03-01 00:00:00

abstract：:Thymus-derived CD4(+)CD25(high)Foxp3(+) T-regulatory cells (Tregs) have an important role in the mechanisms of peripheral immune tolerance and in the prevention of pathogenic autoimmunity through the suppression of proliferation and production of pro-inflammatory cytokines in effector immune cells. Some studies have s...

journal_title：Lupus

authors： La Cava A

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Acute exercise increases IL-6, IL-10 and TNF-α levels in healthy subjects. There is no study evaluating the effect of exercise on cytokines level in systemic lupus erythematosus (SLE) patients. OBJECTIVE:Our aim was to assess IL-10, IL-6 and TNF-α levels at baseline and after acute physical exercise in pati...

journal_title：Lupus

authors： da Silva AE,dos Reis-Neto ET,da Silva NP,Sato EI

更新日期：2013-12-01 00:00:00

abstract：:The heart lesions of rheumatic fever and the heart involvement in antiphospholipid syndrome (APS), have different clinical pictures. Yet, there are several common characteristics linking both diseases: 1) central nervous system (CNS) and heart involvement; 2) molecular mimicry between the a pathogen and the origin of ...

journal_title：Lupus

authors： Blank M,Aron-Maor A,Shoenfeld Y

更新日期：2005-01-01 00:00:00

abstract：:Eosinophilic gastroenteritis (EGE) is an uncommon disease and has rarely been reported in association with connective tissue diseases as systemic lupus erythematosus. We report a 36-year-old woman who developed recurrent episodes of abdominal pain, nausea, vomiting and melena. Complete blood counts showed elevated eos...

journal_title：Lupus

authors： Jaimes-Hernandez J,Aranda-Peirera P,Melendez-Mercado CI

更新日期：2009-04-01 00:00:00

abstract：:Peripheral T cell apoptosis is upregulated in active SLE, in parallel with high expression of both membrane-bound and soluble (s) Fas. Previous studies postulated that sFas down-regulates apoptosis in vitro through its blockade of the Fas-L of cytotoxic cells. We have investigated the extent of apoptosis and sFas leve...

journal_title：Lupus

authors： Silvestris F,Grinello D,Tucci M,Cafforio P,Dammacco F

更新日期：2003-01-01 00:00:00

abstract：:Valvular replacement was performed in a patient with primary antiphospholipid syndrome and severe mitral insufficiency. The valvular tissue presented thrombotic phenomena and fibrosis with minimum inflammatory component. ...

journal_title：Lupus

authors： Alvarez-Blanco A,Egurbide-Arberas MV,Aguirre-Errasti C

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Many studies in adult patients with systemic lupus erythematosus (SLE) have demonstrated that myocardial dysfunction was significantly associated with enhanced disease activity. However, similar studies in paediatric patients with SLE are limited. The aim of this study was to evaluate the role of speckle tra...

journal_title：Lupus

authors： Emara M,Hafez MA,El-Bendary A,Razaky OE

更新日期：2020-10-01 00:00:00

abstract：:This study was conducted to determine kidney transplantation (KTx) outcomes for Greek patients with renal failure caused by lupus nephritis (LN) compared with matched controls, kidney recipients with other causes of end-stage renal disease (ESRD). Twenty-six patients with systemic lupus erythematosus (SLE) subjected t...

journal_title：Lupus

authors： Lionaki S,Kapitsinou PP,Iniotaki A,Kostakis A,Moutsopoulos HM,Boletis JN

更新日期：2008-07-01 00:00:00

abstract：:Poly(ADP-ribose) metabolism is altered in patients with SLE. In order to localize the defect, the levels of poly(ADP-ribose) polymerase-specific mRNA were measured from dot blots of total RNA from peripheral blood lymphocytes. In this preliminary study, eleven patients with SLE and two with antiphospholipid syndrome w...

journal_title：Lupus

authors： Lee JS,Haug BL,Sibley JT

更新日期：1994-04-01 00:00:00

abstract：:Studies have demonstrated considerable variability in systemic lupus erythematosus (SLE) incidence and prevalence estimates. Lack of reliable epidemiological data may hinder evidence-based health care planning. The aim of the present study was to estimate the prevalence and incidence of SLE in the Estonian adult popul...

journal_title：Lupus

authors： Otsa K,Talli S,Harding P,Parsik E,Esko M,Teepere A,Tammaru M

更新日期：2017-09-01 00:00:00

abstract：:Spondyloenchondrodysplasia (SPENCD) is a rare autosomal recessive skeletal dysplasia caused by recessive mutations in the ACP5 gene, and it is characterized by the persistence of chondroid tissue islands within the bone. The clinical spectrum of SPENCD includes neurological involvement and immune dysfunction, such as ...

journal_title：Lupus

authors： Bilginer Y,Düzova A,Topaloğlu R,Batu ED,Boduroğlu K,Güçer Ş,Bodur I,Alanay Y

更新日期：2016-06-01 00:00:00

abstract：:Atherosclerosis may represent a significant cause of death and morbidity in patients with systemic lupus erythematosus. Coronary involvement is more premature in lupus patients. We present the case of a young woman diagnosed with SLE at the age of 20 years who had a myocardial infarction at age 29 years. We review the...

journal_title：Lupus

authors： Farhey Y,Hess EV

更新日期：1997-01-01 00:00:00

abstract：:To assess bladder function in systemic lupus erythematosus (SLE) patients with recurrent urinary tract infections (UTIs). A convenience sample of consecutive patients with SLE (American College of Rheumatology criteria), with recurrent UTIs (>/=3 events in the preceding 12 months), without history of central nervous s...

journal_title：Lupus

authors： Duran-Barragan S,Ruvalcaba-Naranjo H,Rodriguez-Gutierrez L,Solano-Moreno H,Hernandez-Rios G,Sanchez-Ortiz A,Ramos-Remus C

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:We sought to describe characteristics of children admitted with pericardial effusion (PCE) and systemic lupus erythematosus (SLE) and determine the association between PCE and outcomes of interest. METHODS:We performed a retrospective cohort study of the Pediatric Health Information System (PHIS). Patients w...

journal_title：Lupus

authors： Dalby ST,Tang X,Daily JA,Sukumaran S,Collins RT,Bolin EH

更新日期：2019-03-01 00:00:00

abstract：:The mouse model described in this study offers a unique method of determining the characteristics and mechanism(s) of action of aCL antibodies in thrombosis in vivo. In addition, this animal model enables the study of the kinetics of formation and dissolution of thrombus, as well as clot area, to be studied in a dynam...

journal_title：Lupus

authors： Pierangeli SS,Harris EN

更新日期：1994-08-01 00:00:00

abstract：OBJECTIVE:The heterogeneous spectrum of systemic lupus erythematosus (SLE) often presents with secondary complications such as cardiovascular disease (CVD), infections and neoplasms. Our study assessed whether the presence of SLE independently increases or reduces the disparities, accounting for the already higher risk...

journal_title：Lupus

authors： Falasinnu T,Chaichian Y,Li J,Chung S,Waitzfelder BE,Fortmann SP,Palaniappan L,Simard JF

更新日期：2019-12-01 00:00:00

abstract：:With a cross sectional study of 465 consecutive systemic lupus erythematosus (SLE) patients tested for 13 autoantibodies (Aab) and two idiotypes we determined the prevalence of Aab according to disease activity, both general and at particular organ systems. Seventy seven percent of SLE sera had at least one Aab and 56...

journal_title：Lupus

authors： Villarreal GM,Drenkard C,Villa AR,Slor H,Shafrir S,Bakimer R,Shoenfeld Y,Alarcón-Segovia D

更新日期：1997-01-01 00:00:00

abstract：:'Antiphospholipid' (aPL) antibodies are of clinical importance because of their strong association with vascular thrombosis, recurrent pregnancy loss, thrombocytopenia and other clinical manifestations like livedo reticularis, chorea and cardiac valvular disease. While aPL antibodies have traditionally been thought to...

journal_title：Lupus

authors： Kandiah DA,Krilis SA

更新日期：1996-04-01 00:00:00