Visceral leishmaniasis complicating a connective tissue disease: three case reports from Italy.

abstract：:Mycophenolate mofetil (MMF) is effective in the treatment of patients with active systemic lupus erythematosus (SLE). We sought to evaluate its efficacy in reducing the number of disease flares in adults with SLE. For this retrospective study, all patients seen at our institution over a six year period, 1999-2005, wit...

journal_title：Lupus

authors： Nannini C,Crowson CS,Matteson EL,Moder KG

更新日期：2009-04-01 00:00:00

abstract：:Background and objective African-Americans and Hispanic-Americans with lupus are the two most common minority groups who receive kidney transplants in the USA. It is unknown if African-Americans and Hispanic-Americans with lupus have similar outcomes after kidney transplantation. In this study, we assessed whether Afr...

journal_title：Lupus

authors： Gonzalez-Suarez ML,Contreras G

更新日期：2017-10-01 00:00:00

abstract：:In order to ascertain the incidence of monoclonal gammopathy (MG) in systemic lupus erythematosus (SLE), 120 SLE patients were evaluated. Four patients (3.3%), two of whom were under 50 years of age, were found to have a monoclonal immunoglobulin in their serum. Our data agree with the previous literature in demonstra...

journal_title：Lupus

authors： Porcel JM,Ordi J,Tolosa C,Selva A,Castro-Salomo A,Vilardell M

更新日期：1992-08-01 00:00:00

abstract：:We report the case of a fetus with proliferative glomerulonephritis in the context of maternal systemic lupus erythematosus (SLE). The pattern of the renal lesions correspond to the class III of revisited WHO classification of glomerulonephritis in SLE. Amniotic fluid analysis showed a high level of albumin and the pr...

journal_title：Lupus

authors： Daïkha-Dahmane F,Bault JP,Molina-Gomes D,Hillion D,Ville Y

更新日期：2005-01-01 00:00:00

abstract：:Patients with chronic hepatitis C virus (HCV) infection frequently present with extrahepatic manifestations covering a large spectrum, involving different organ systems leading to the concept of systemic HCV infection. These manifestations include autoimmune phenomena and frank autoimmune and/or rheumatic diseases and...

journal_title：Lupus

authors： Rosenthal E,Cacoub P

更新日期：2015-04-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is one of the most heterogeneous autoimmune disorders known. There is production of a variety of autoantibodies and patients present with a wide range of symptoms due to multiple organ involvement by the disease process. The underlying cause is not fully understood but it may involve...

journal_title：Lupus

authors： Lau CS,Yin G,Mok MY

更新日期：2006-01-01 00:00:00

abstract：:We describe seven patients who developed malignancy before, after or at the onset of systemic lupus erythematosus (SLE). They comprise three cases of breast adenocarcinoma, two cases of Hodgkin's lymphoma, and one each of cholangiocarcinoma and thymoma. Only one of this group had been treated with cytotoxic agents, an...

journal_title：Lupus

authors： Menon S,Snaith ML,Isenberg DA

更新日期：1993-06-01 00:00:00

abstract：INTRODUCTION:Anti-RNP autoantibodies occur either in mixed connective tissue disease (MCTD) (with a frequently favorable prognosis), or in systemic lupus erythematosus (SLE) cases with aggressive major organ disease. It is uncertain how to assess for the risk of severe disease in anti-RNP + patients. METHODS:Following...

journal_title：Lupus

authors： Carpintero MF,Martinez L,Fernandez I,Romero AC,Mejia C,Zang YJ,Hoffman RW,Greidinger EL

更新日期：2015-09-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is a connective tissue disease where inflammatory activity affects several organ systems. An increased risk of cardiovascular disease has been identified in these patients, even after correction for traditional risk factors. The aim of the present study was to evaluate arterial stiff...

journal_title：Lupus

authors： Bjarnegråd N,Bengtsson C,Brodszki J,Sturfelt G,Nived O,Länne T

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Ferritin is an iron storage protein considered also as an acute phase reactant with high levels in various inflammatory conditions. Recently, a plausible role for ferritin in the pathogenesis of immune-mediated and especially autoimmune diseases has been suggested. However, the link between ferritin and the ...

journal_title：Lupus

authors： Agmon-Levin N,Rosário C,Katz BS,Zandman-Goddard G,Meroni P,Cervera R,Stojanovich L,Blank M,Pierangeli S,Praprotnik S,Meis Ed,Seguro LP,Ruffatti A,Pengo V,Tincani A,Doria A,Shoenfeld Y

更新日期：2013-11-01 00:00:00

abstract：:Congenital heart block (CHB) is a syndrome of uncertain pathogenesis leading to cardiac conduction disturbances in the foetus and newborns. It has been proposed that maternal antibodies transmit immunological injury in the developing foetal heart, thus causing irreversible damage of the atrioventricular node, leading ...

journal_title：Lupus

authors： Sirén MK,Julkunen H,Kaaja R,Ekblad H,Koskimies S

更新日期：1999-01-01 00:00:00

abstract：:Objective The objective of this study was to describe the clinical and immunological pattern and disease outcome in Egyptian systemic lupus erythematosus patients. Patients and methods The medical records of 770 systemic lupus erythematosus patients who were followed from 2002-2015 at Kasr Alainy Hospital, Cairo Unive...

journal_title：Lupus

authors： Mahmoud GA,Shahin AA,Zayed HS,Moghazy A,Eissa BM

更新日期：2018-08-01 00:00:00

abstract：:We report a case of drug-induced lupus erythematosus (DILE) secondary to trimethoprim/sulfamethoxazole (TMP/SMX) in a patient with underlying inflammatory bowel disease (IBD). The initial presentation was with febrile pleural and pericardial effusions followed by cardiac tamponade. The patient was treated with a short...

journal_title：Lupus

authors： Jose A,Cramer AK,Davar K,Gutierrez G

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVES:Systemic lupus erythematosus (SLE) is a chronic, multisystemic, immune-mediated disorder associated with a substantial hospitalization risk. As a comparatively rare disease, there is a sparsity of research examining the burden of hospital admission in the contemporary era. We aim to describe national trends ...

journal_title：Lupus

authors： Hannah J,Galloway J,Kaul A

更新日期：2019-06-01 00:00:00

abstract：:The use of TNF alpha (TNFalpha) inhibitors has made a strong impact on the management of rheumatoid and psoriatic arthritis, ankylosing spondylitis and Crohn disease. Side effects of these agents include the development of autoantibodies and a lupus-like syndrome (drug-related lupus, DRL). Here, a case of a patient wh...

journal_title：Lupus

authors： Kocharla L,Mongey AB

更新日期：2009-02-01 00:00:00

abstract：:Multiple sources were used to identify 325 systemic lupus erythematosus (SLE) patients within the city of Oslo during 1999-2009 who met ≥ 4 of the American College of Rheumatology (ACR) criteria. The survival, standard mortality rate (SMR), years of potential life loss before 60 years of age (YPLL60) and causes of dea...

journal_title：Lupus

authors： Lerang K,Gilboe IM,Steinar Thelle D,Gran JT

更新日期：2014-12-01 00:00:00

abstract：:Introduction White matter hyperintense (WMHI) lesions are the most common finding in magnetic resonance imaging (MRI) of the brain in patients with systemic lupus erythematosus (SLE). Objective The objective of this article is to determine the clinical factors associated with an increase in WMHI lesion load among SLE ...

journal_title：Lupus

authors： Shaharir SS,Osman SS,Md Rani SA,Sakthiswary R,Said MSM

更新日期：2018-01-01 00:00:00

abstract：:A case of recurrent cerebral infarctions in a 42-year-old woman affected by polyarteritis nodosa and antiphospholipid syndrome is reported. Two-dimensional echocardiography revealed grossly thickened mitral valve leaflets, possibly related to the presence of antiphospholipid antibodies. Thus, an embolic source at mitr...

journal_title：Lupus

authors： Morelli S,Perrone C,Paroli M

更新日期：1998-01-01 00:00:00

abstract：:Female B6.MRLc1(82-100) congenic mice develop more severe autoimmune glomerulonephritis (AGN) than males. We assessed the effects of gonadectomy on the pathogenesis of AGN in these mice. One-month-old male and female mice were divided into sham-operated group (SG) and gonadectomized group (GG), and the pathological ch...

journal_title：Lupus

authors： Ichii O,Konno A,Sasaki N,Endoh D,Hashimoto Y,Kon Y

更新日期：2009-05-01 00:00:00

abstract：:We have explored the relationship between possible hemostatic changes and clinical manifestation of the systemic lupus erythematosus (SLE) as a function of greater or lesser disease activity according to Systemic Lupus Erythematosus Disease Activity Index-2000 (SLEDAI-2K) criteria. Endothelial injury and hypercoagulab...

journal_title：Lupus

authors： Cicarini WB,Duarte RCF,Ferreira KS,Loures CMG,Consoli RV,Neiva CLS,de Pádua PM,Nunes FFC,Alves LCV,Reis EA,Moreira CC,Guimarães TMPD,de Toledo VPCP,Carvalho MDG

更新日期：2020-02-01 00:00:00

abstract：:The relationship between disease activity, cumulative damage and self-reported quality of life was examined in 96 patients with Systematic Lupus Erythematosus (SLE). Disease activity was measured by the SLE Disease Activity Index (SLEDAI) and cumulative damage by the Systematic Lupus International Cooperating Clinics/...

journal_title：Lupus

authors： Hanly JG

更新日期：1997-01-01 00:00:00

abstract：:Antiphospholipid antibodies (aPL) have been detected in various liver diseases, particularly cirrhosis. The role of alcoholic consumption per se has been suggested. The aim of our study was to assess the prevalence of aPL in patients with alcoholic liver disease at various states and to correlate the presence of aPL w...

journal_title：Lupus

authors： Perney P,Biron-Andréani C,Joomaye Z,Fabbro-Peray P,Quénet F,Schved JF,Blanc F

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVES:Sexual dysfunction in systemic lupus erythematous (SLE) patients is an important issue to be tackled. We aimed to study the prevalence of sexual dysfunction in SLE women and detect its association with depression, functional disability and quality of life. METHODS:This study included 94 SLE females. Ninety-...

journal_title：Lupus

authors： Dorgham D,Haggag HM,Attia DH

更新日期：2020-08-01 00:00:00

abstract：:Mycophenolate mofetil (MMF) initially found widespread use in the immunoprophylaxis of rejection in organ transplantation. It has subsequently been used in lupus glomerulonephritis, where early studies have shown it to be effective in induction and maintenance therapy. The randomized studies have mostly studied small ...

journal_title：Lupus

authors： Karim MY,Abbs IC

更新日期：2005-01-01 00:00:00

abstract：:Valvular replacement was performed in a patient with primary antiphospholipid syndrome and severe mitral insufficiency. The valvular tissue presented thrombotic phenomena and fibrosis with minimum inflammatory component. ...

journal_title：Lupus

authors： Alvarez-Blanco A,Egurbide-Arberas MV,Aguirre-Errasti C

更新日期：1994-10-01 00:00:00

abstract：:Endothelial and/or platelet activation likely initiates thrombus formation. Whether antiphospholipid antibody (aPL) is an activator, a toxic response, or a protective response is not clear, nor is it certain whether aPL is germ-line encoded or antigen-driven. The pregnancy model is particularly informative. Alternativ...

journal_title：Lupus

authors： Lockshin MD

更新日期：1996-10-01 00:00:00

abstract：:Background Systemic lupus erythematosus (SLE) is an autoimmune disease marked by the disruption of the immune homeostasis. Patients exhibit a wide range of clinical manifestations, and environmental and genetic factors are involved in SLE pathogenesis. Evidence suggests that abnormalities in the cellular and molecular...

journal_title：Lupus

authors： Glesse N,Vianna P,Paim LMG,Matte MCC,Aguiar AKK,Palhano PL,Monticielo OA,Brenol CV,Xavier RM,Chies JAB

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:Anti-α-enolase antibody (Ab) combined with β2 microglobulin (β2-MG) were investigated to predict the incidence of nephritis in systemic lupus erythematosus (SLE) patients. METHODS:Levels of serum anti-α-enolase Ab and urinary β2-MG were detected in 115 SLE patients, 29 SLE patients with nephritis and 70 heal...

journal_title：Lupus

authors： Huang Y,Chen L,Chen K,Huang F,Feng Y,Xu Z,Wang W

更新日期：2019-03-01 00:00:00

abstract：:Structural and metabolic abnormalities in the hippocampus have been associated with the pathophysiological mechanism of central nervous system involvement in primary Sjögren syndrome (pSS). Nevertheless, how hippocampal function is altered in pSS remains unknown. The purpose of our study is to investigate the alterati...

journal_title：Lupus

authors： Zhang XD,Zhao LR,Zhou JM,Su YY,Ke J,Cheng Y,Li JL,Shen W

更新日期：2020-04-01 00:00:00

abstract：:Recent accumulated evidence suggests that prolactin (PRL) is an important immunomodulator and might have a role in the pathogenesis of systemic lupus erythematosus (SLE). Our aim was to assess the frequency of hyperprolactinemia in women with SLE and to evaluate its correlation with disease activity. PRL plasma levels...

journal_title：Lupus

authors： Jimena P,Aguirre MA,López-Curbelo A,de Andrés M,Garcia-Courtay C,Cuadrado MJ

更新日期：1998-01-01 00:00:00