Anti-α-enolase antibody combined with β2 microglobulin evaluated the incidence of nephritis in systemic lupus erythematosus patients.

abstract：:Systemic lupus erythematosus (SLE) is an autoantibody and immune complex mediated disease. However, it is the ensuing inflammatory process that leads to irreversible organ damage. In fact several murine models of SLE suggest that this inflammatory organ damage can be prevented even in the presence of autoantibodies. G...

journal_title：Lupus

authors： Aringer M,Smolen JS

更新日期：2004-01-01 00:00:00

abstract：:To assess bladder function in systemic lupus erythematosus (SLE) patients with recurrent urinary tract infections (UTIs). A convenience sample of consecutive patients with SLE (American College of Rheumatology criteria), with recurrent UTIs (>/=3 events in the preceding 12 months), without history of central nervous s...

journal_title：Lupus

authors： Duran-Barragan S,Ruvalcaba-Naranjo H,Rodriguez-Gutierrez L,Solano-Moreno H,Hernandez-Rios G,Sanchez-Ortiz A,Ramos-Remus C

更新日期：2008-12-01 00:00:00

abstract：:Objectives We analyzed the clinical follow-up results of 88 lupus nephritis patients to find prognostic factors for the development of chronic kidney disease in ethnically homogeneous Korean patients with biopsy-proven lupus nephritis. Methods Sociodemographic, clinical, laboratory, and treatment-related data at the t...

journal_title：Lupus

authors： Park DJ,Kang JH,Lee JW,Lee KE,Kim TJ,Park YW,Lee JS,Choi YD,Lee SS

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:We compared the 1997 update of the 1982 American College of Rheumatology (ACR-97) and the 2012 Systemic Lupus International Collaborating Clinics (SLICC-12) criteria, for earlier classification of systemic lupus erythematosus (SLE) in a multiethnic urban Asian SLE population. METHODS:Patients from a retrospe...

journal_title：Lupus

authors： Low ESH,Krishnaswamy G,Thumboo J

更新日期：2019-01-01 00:00:00

abstract：:Renal involvement is one of the main complications of systemic lupus erythematosus, causing a significant impact on patients' morbidity and mortality. Renal biopsy is still the gold standard of diagnosis, but it has many limitations. In this sense, several recent studies aim to identify biomarkers that not only predic...

journal_title：Lupus

authors： Gasparin AA,Pamplona Bueno de Andrade N,Hax V,Tres GL,Veronese FV,Monticielo OA

更新日期：2019-03-01 00:00:00

abstract：:Objectives The carotid intima-media thickness (CIMT) and carotid arterial stiffness index (CASI) act as the surrogate markers of atherosclerosis. We aim to assess CIMT and CASI in pediatric systemic lupus erythematosus (SLE). Methods Patients ≤ 20 years old fulfilling diagnostic criteria for SLE were enrolled. Patient...

journal_title：Lupus

authors： Su-Angka N,Khositseth A,Vilaiyuk S,Tangnararatchakit K,Prangwatanagul W

更新日期：2017-08-01 00:00:00

abstract：:We report clinical and histopathological features, treatment and outcome of 37 Croatian children with biopsy-proven lupus nephritis seen over a 30-year period. The mean age at lupus nephritis presentation was 12.11 ± 2.59 years (range 4.66-17.0). The most frequent histopathological finding was class IV (37.8%), follow...

journal_title：Lupus

authors： Batinić D,Milošević D,Čorić M,Topalović-Grković M,Jelušić M,Turudić D

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:Systemic lupus erythematosus (SLE), an autoimmune condition with diverse clinical manifestations, is reported to have different expression in populations of different ancestry. Most previous studies compared patients of different ethnic groups from geographically distinct cohorts. In our study, we aimed to ch...

journal_title：Lupus

authors： Golder V,Connelly K,Staples M,Morand E,Hoi A

更新日期：2013-11-01 00:00:00

abstract：:Obstetric antiphospholipid syndrome (APS) remains a clinical challenge for practitioners, with several controversial points that have not been answered so far. This Obstetric APS Task Force met on the 16th International Congress on Antiphospholipid Antibodies in Manchester, England, to discuss about treatment, diagnos...

journal_title：Lupus

authors： de Jesús GR,Benson AE,Chighizola CB,Sciascia S,Branch DW

更新日期：2020-10-01 00:00:00

abstract：PURPOSE:To describe the ocular and systemic manifestations associated with systemic lupus erythematosus (SLE) choroidopathy. METHODS:Three new cases of choroidopathy in patients with active SLE were described. Twenty-five published cases of lupus choroidopathy were summarized. RESULTS:There have been 28 cases of lupu...

journal_title：Lupus

authors： Nguyen QD,Uy HS,Akpek EK,Harper SL,Zacks DN,Foster CS

更新日期：2000-01-01 00:00:00

abstract：:A 22-year-old female with history of systemic lupus erythematosus (SLE) was referred for evaluation of decreased visual acuity in her right eye. Her best-corrected visual acuity (BCVA) at the time of presentation was 20/160. Widespread cotton wool spots and macular edema were seen on biomicroscopy. Fluorescein angiogr...

journal_title：Lupus

authors： Jeon S,Lee WK

更新日期：2012-03-01 00:00:00

abstract：:Pancreatitis is a relatively rare complication in systemic lupus erythematosus (SLE). Here we present a case of SLE associated with autoimmune pancreatitis. A 37-year old woman was admitted to our hospital because of fever, skin rash, proteinuria and abdominal pain. A diagnosis of SLE was made based on her clinical, l...

journal_title：Lupus

authors： Kobayashi S,Yoshida M,Kitahara T,Abe Y,Tsuchida A,Nojima Y

更新日期：2007-01-01 00:00:00

abstract：:The main objective of this study is to describe the presence of infections in patients with pulmonary haemorrhage and systemic lupus erythematosus. Patients with systemic lupus erythematosus and pulmonary haemorrhage were thoroughly evaluated in the first 48 hours with imaging plus bronchoscopy and bronchoalveolar flu...

journal_title：Lupus

authors： Rojas-Serrano J,Pedroza J,Regalado J,Robledo J,Reyes E,Sifuentes-Osornio J,Flores-Suárez LF

更新日期：2008-04-01 00:00:00

abstract：:Heart valve disease (HVD) is the most common cardiac manifestation in the antiphospholipid syndrome (APS). Valve lesions should be described according to the established definition. HVD is progressive despite anticoagulant/antiplatelet treatments. Around 4-6% of patients with HVD in APS will require valve replacement ...

journal_title：Lupus

authors： Amigo MC

更新日期：2014-10-01 00:00:00

abstract：:Catastrophic antiphospholipid syndrome (CAPS) is an acutely devastating situation characterized by widespread thrombotic microangiopathy in the presence of elevated titers of antiphospholipid antibodies. We describe a 57-year old woman who underwent liver transplantation for primary sclerosing cholangitis and develope...

journal_title：Lupus

authors： Villamil A,Sorkin E,Basta MC,Mysler E,Macias S,Pekolj J,Ciardullo M,Eleta F,de Santibañes E,Allievi A,Gadano A

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To determine whether the intrathecal concentrations of cytokines/chemokines are associated with, or influenced by, serum concentrations in patients with central neuropsychiatric systemic lupus erythematosus (NPSLE), and to ascertain whether the increased production of cytokines/chemokines intrathecally relati...

journal_title：Lupus

authors： Yoshio T,Okamoto H,Kurasawa K,Dei Y,Hirohata S,Minota S

更新日期：2016-08-01 00:00:00

abstract：:Anti-tumor necrosis factor-alpha (TNF-α) immunotherapy is currently used in the treatment of various inflammatory diseases such as rheumatoid arthritis, psoriasis, psoriatic arthritis, ankylosing spondylitis and Crohn's disease. Infliximab is a chimeric monoclonal antibody that binds to transmembrane-bound and soluble...

journal_title：Lupus

authors： Cemil BC,Atas H,Canpolat F,Akca Y,Sasmaz R

更新日期：2013-04-01 00:00:00

abstract：:This study was conducted to determine kidney transplantation (KTx) outcomes for Greek patients with renal failure caused by lupus nephritis (LN) compared with matched controls, kidney recipients with other causes of end-stage renal disease (ESRD). Twenty-six patients with systemic lupus erythematosus (SLE) subjected t...

journal_title：Lupus

authors： Lionaki S,Kapitsinou PP,Iniotaki A,Kostakis A,Moutsopoulos HM,Boletis JN

更新日期：2008-07-01 00:00:00

abstract：:'Antiphospholipid' (aPL) antibodies are of clinical importance because of their strong association with vascular thrombosis, recurrent pregnancy loss, thrombocytopenia and other clinical manifestations like livedo reticularis, chorea and cardiac valvular disease. While aPL antibodies have traditionally been thought to...

journal_title：Lupus

authors： Kandiah DA,Krilis SA

更新日期：1996-04-01 00:00:00

abstract：:Belimumab is a monoclonal antibody against soluble B-lymphocyte stimulator, an essential growth factor for B-cell maturation and activation, which was approved by the US FDA in 2011 for patients with active autoantibody-positive systemic lupus erythematosus (SLE) who have failed standard treatment. Here we present the...

journal_title：Lupus

authors： Fredericks CA,Kvam KA,Bear J,Crabtree GS,Josephson SA

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Plasma mycophenolic acid (MPA) concentrations may predict therapeutic response in active lupus nephritis (LN). We determined the efficacy and safety of a concentration-controlled MPA regime in the treatment of severely active LN. METHODS:In this prospective study, 19 biopsy-proven class III/IV LN patients w...

journal_title：Lupus

authors： Kittanamongkolchai W,Rukrung C,Supasiri T,Lertjirachai I,Somparn P,Chariyavilaskul P,Avihingsanon Y

更新日期：2013-06-01 00:00:00

abstract：:The presence of antibodies against the complex of prothrombin and phosphatidylserine (aPS/PT) more significantly correlates with manifestations of antiphospholipid syndrome (APS) and with the presence of lupus anticoagulants (LA) than antibodies against prothrombin bound to oxygenated polystyrene (aPT-A). To investiga...

journal_title：Lupus

authors： Horita T,Ichikawa K,Kataoka H,Yasuda S,Atsumi T,Koike T

更新日期：2007-01-01 00:00:00

abstract：:The aim of this study was to determine the frequency of anti-prolactin autoantibodies and the relationship among anti-prolactin autoantibodies, serum prolactin (PRL) levels and lupus activity in paediatric patients with systemic lupus erythematosus (SLE) using a transversal study. One-hundred and three consecutive pae...

journal_title：Lupus

authors： Blanco-Favela F,Quintal MaG,Chavez-Rueda AK,Leaños-Miranda A,Berron-Peres R,Baca-Ruiz V,Lavalle-Montalvo C

更新日期：2001-01-01 00:00:00

abstract：:Although a few reports in recent years have suggested that patients with antiphospholipid antibodies (aPL) are prone to developing primary anetoderma (PA), it is still unclear how often aPL are detected in unselected PA patients. We studied nine consecutive PA patients for the presence of autoimmune antibodies and dis...

journal_title：Lupus

authors： Hodak E,Feuerman H,Molad Y,Monselise Y,David M

更新日期：2003-01-01 00:00:00

abstract：:We studied the effect of beta 2-GPI on binding of antibodies in sera from patients with leprosy and patients with the antiphospholipid syndrome (APS) to CL in enzyme-linked immunosorbent assays (ELISAs). Increased levels of IgG aCL were detected in 59 of 61 leprosy patients' sera by the standard aCL-ELISA in the prese...

journal_title：Lupus

authors： Hojnik M,Gilburd B,Ziporen L,Blank M,Tomer Y,Scheinberg MA,Tincani A,Rozman B,Shoenfeld Y

更新日期：1994-12-01 00:00:00

abstract：:Results for lupus anticoagulant (LA) are expressed as ratio of patient-to-normal clotting times (LA-ratio) according to the equation LA-ratio = (Patient(Clotting time)/Normal(Clotting time)). However, numerical results vary according to the method used for testing, thus making difficult the between-method and between-...

journal_title：Lupus

authors： Tripodi A,Chantarangkul V,Pengo V

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Cognitive dysfunction (CD) is among the most common neuropsychiatric manifestations of systemic lupus erythematosus (SLE). There are two methods which have been used to detect CD in patients with SLE: traditional neuropsychological tests (NPT) and the Automated Neuropsychological Assessment Metrics (ANAM). B...

journal_title：Lupus

authors： Adhikari T,Piatti A,Luggen M

更新日期：2011-10-01 00:00:00

abstract：:Neuropsychiatric lupus is a well-recognized complication of systemic lupus erythematosus (SLE) and encompasses a wide variety of neurological manifestations. Although isolated cranial nerve involvement is rare, it can cause significant morbidity and disability. This report describes a case with isolated vagus nerve in...

journal_title：Lupus

authors： Yu KH,Yang CH,Chu CC

更新日期：2007-01-01 00:00:00

abstract：:To evaluate the efficacy of hydroxychloroquine (HCQ) and quinacrine (Qn) association, at two different dosages, in treatment of lupus skin lesions not responding to HCQ alone. Thirty-four patients, affected by cutaneous and systemic lupus erythematosus, were retrospectively analysed. They were treated by HCQ (5 mg/Kg/...

journal_title：Lupus

authors： Cavazzana I,Sala R,Bazzani C,Ceribelli A,Zane C,Cattaneo R,Tincani A,Calzavara-Pinton PG,Franceschini F

更新日期：2009-07-01 00:00:00

abstract：:The complexity of the therapeutic approach in systemic lupus erythematosus (SLE) is increased by the large number of patients who do not respond to the first-line therapies and by relapses after initial clinical remission. In these patients, second-line drugs are often prescribed according to individual clinical decis...

journal_title：Lupus

authors： Ramos-Casals M,Soto MJ,Cuadrado MJ,Khamashta MA

更新日期：2009-08-01 00:00:00