Abstract:
:Neuropsychiatric lupus is a well-recognized complication of systemic lupus erythematosus (SLE) and encompasses a wide variety of neurological manifestations. Although isolated cranial nerve involvement is rare, it can cause significant morbidity and disability. This report describes a case with isolated vagus nerve involvement as the principal sign of central nervous system involvement. A 30-year-old female with SLE had one short course of lupus-associated psychosis in December 2001. In August 2002, the patient suffered from progressive swallowing difficulty, developed a transient episode of hypercapnic respiratory failure and required nasogastric tube feeding due to isolated vagus nerve involvement. Magnetic resonance imaging revealed a subtle but distinct brainstem lesion over the ponto-medullary junction, near the location of the vagus nerve nuclei. The patient completely recovered three weeks later following treatment with intravenous dexamethasone. This report also discusses the differential diagnosis of this rare condition.
journal_name
Lupusjournal_title
Lupusauthors
Yu KH,Yang CH,Chu CCdoi
10.1177/0961203307080632subject
Has Abstractpub_date
2007-01-01 00:00:00pages
746-9issue
9eissn
0961-2033issn
1477-0962pii
16/9/746journal_volume
16pub_type
杂志文章相关文献
LUPUS文献大全abstract:OBJECTIVE:We analyzed data of lupus nephritis (LN) patients to find parameters that can predict remission. METHODS:Sixty-four LN patients who were diagnosed with class III, IV, V or V + III/IV by renal biopsy and were followed up for more than six months in our center were enrolled retrospectively. Receiver operating ...
journal_title:Lupus
pub_type: 杂志文章
doi:10.1177/0961203319826703
更新日期:2019-03-01 00:00:00
abstract::Analyses of the medical and economic burden of chronic disorders such as systemic lupus erythematosus (SLE) are valuable for clinical and health policy decisions. We performed a chart-based review of 215 adult SLE patients with active autoantibody-positive disease at the predefined ratio of 30% severe (involvement of ...
journal_title:Lupus
pub_type: 杂志文章
doi:10.1177/0961203316642310
更新日期:2016-10-01 00:00:00
abstract:INTRODUCTION:Patients with systemic lupus erythematosus (SLE) with B-lymphocyte stimulator (BLyS) levels ≥ 2 ng/mL are at increased risk of flare. A regression analysis was undertaken to identify routine clinical measures that correlate with BLyS ≥ 2 ng/mL. Efficacy and safety of belimumab 10 mg/kg were examined in pat...
journal_title:Lupus
pub_type: 杂志文章
doi:10.1177/0961203315604909
更新日期:2016-04-01 00:00:00
abstract::We report clinical and histopathological features, treatment and outcome of 37 Croatian children with biopsy-proven lupus nephritis seen over a 30-year period. The mean age at lupus nephritis presentation was 12.11 ± 2.59 years (range 4.66-17.0). The most frequent histopathological finding was class IV (37.8%), follow...
journal_title:Lupus
pub_type: 杂志文章
doi:10.1177/0961203314563133
更新日期:2015-03-01 00:00:00
abstract::Previous studies in our laboratory showed a dose-dependent and hormone-specific increase in CD154 expression in T cells from females with systemic lupus erythematosus (SLE). This present study investigates if the estrogen-dependent increase in CD154 expression is due to stabilization of the messenger RNA. T cells from...
journal_title:Lupus
pub_type: 杂志文章
doi:10.1177/0961203306071314
更新日期:2006-01-01 00:00:00
abstract::Neurological involvement in antiphospholipid antibody syndrome (APS) is common, and its occurrence increases morbidity and mortality. Patients may present variable neurological involvement, such as cerebrovascular disease, cognitive dysfunction, headache, seizures, movement disorders, multiple sclerosis-like syndrome,...
journal_title:Lupus
pub_type: 杂志文章,评审
doi:10.1177/0961203318776110
更新日期:2018-08-01 00:00:00
abstract::We report three cases of severe haemorrhagic rupture of luteal ovarian cyst requiring surgical haemostasis in young women treated with long-term oral anticoagulation for antiphospholipid syndrome (APS) who used no contraception. At the time of bleeding, the international normalized ratios were 3.78, 4.24, and 7.11. An...
journal_title:Lupus
pub_type: 杂志文章
doi:10.1177/096120339900800614
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:Current non-invasive methods of assessing disease activity in systemic lupus erythematosus (SLE) are of limited sensitivity and specificity. Testing includes acute phase markers, autoantibodies and complement levels. Although measurements of dsDNA antibodies and complement C3/C4 levels are routine, they rema...
journal_title:Lupus
pub_type: 杂志文章
doi:10.1177/0961203319845487
更新日期:2019-05-01 00:00:00
abstract::To study whether monoclonal anticardiolipin antibodies (aCL), derived from patients with antiphospholipid syndrome (APS), have similar pathogenic potential, we have employed an experimental model of antiphospholipid syndrome. Monoclonal aCL were produced by the combined method of EBV transformation and somatic cell hy...
journal_title:Lupus
pub_type: 杂志文章
doi:10.1177/096120339500400307
更新日期:1995-06-01 00:00:00
abstract::Systemic lupus erythematosus (SLE) is characterized by multiple autoantibodies and complement activation. Recent studies have suggested that anti-nuclear antibody (ANA) positivity may disappear over time in some SLE patients. Anti-double-stranded DNA (dsDNA) antibody titers and complement levels may vary with time and...
journal_title:Lupus
pub_type: 历史文章,杂志文章
doi:10.1177/0961203310385738
更新日期:2011-03-01 00:00:00
abstract::Antiphospholipid antibodies (aPL) are associated with an increased incidence of fetal loss, but the pathophysiology remains unclear. One mechanism may involve the binding of aPL directly to the placenta where they may initiate placental thrombosis and infarction. We have developed an immunofluorescent technique to det...
journal_title:Lupus
pub_type: 杂志文章
doi:10.1191/096120399678840756
更新日期:1999-01-01 00:00:00
abstract::This is a case report on an uncommon correlation between periodic lateralized epileptiform discharges (PLEDs) and white-matter lesions in cerebral lupus, and with a reduced cerebral blood flow (CBF) in single-photon emission computed tomography (SPECT). A 47-year-old woman with a long-term history of systemic lupus er...
journal_title:Lupus
pub_type: 杂志文章
doi:10.1177/0961203312474705
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Pregnancies in women with systemic lupus erythematosus (SLE) and lupus nephritis are considered high-risk due to high rates of maternal and fetal complications. However, there has not been a formal analysis addressing the issue of maternal deaths in these women. The aim of this study was to pe...
journal_title:Lupus
pub_type: 杂志文章,评审
doi:10.1177/0961203311434939
更新日期:2012-04-01 00:00:00
abstract::Atherosclerosis is an inflammatory disease, leading to the formation of pro-inflammatory and pro-oxidative lipids that generate an immune response. Several antigens have been shown to activate the immune response and affect the development of atherogenesis. Systemic lupus erythematosus is an autoimmune and inflammator...
journal_title:Lupus
pub_type: 杂志文章
doi:10.1177/0961203309345725
更新日期:2009-11-01 00:00:00
abstract::A 26-year-old Japanese female presented to us with a 2-year history of multiple arc-shaped erythematous lesions on her scalp and the right side of her forehead. Histopathological examination of two of the lesions showed lobular and septal panniculitis with deposits of IgG in the basement membrane zone. We diagnosed th...
journal_title:Lupus
pub_type: 杂志文章,评审
doi:10.1177/0961203311433917
更新日期:2012-05-01 00:00:00
abstract::This study was conducted to determine kidney transplantation (KTx) outcomes for Greek patients with renal failure caused by lupus nephritis (LN) compared with matched controls, kidney recipients with other causes of end-stage renal disease (ESRD). Twenty-six patients with systemic lupus erythematosus (SLE) subjected t...
journal_title:Lupus
pub_type: 杂志文章
doi:10.1177/0961203308089430
更新日期:2008-07-01 00:00:00
abstract::C4d deposition in peritubular capillaries (PTC) has been used as a marker of antibody-mediated rejection (AMR). However, PTC C4d deposition is not described in patients with lupus nephritis (LN). C4d deposition in PTC was detected in 455 patients with biopsy proven LN in the present study. Renal tissues from 21 cases ...
journal_title:Lupus
pub_type: 杂志文章
doi:10.1177/0961203307083279
更新日期:2007-01-01 00:00:00
abstract::Chronic intestinal pseudo-obstruction (CIPO) is a rare clinical syndrome of ineffective intestinal motility characterised by clinical and radiological evidence of intestinal obstruction with no identifiable mechanical lesion. CIPO can either be idiopathic or secondary to a systemic disease, like systemic lupus erythem...
journal_title:Lupus
pub_type: 杂志文章,评审
doi:10.1177/0961203313492873
更新日期:2013-08-01 00:00:00
abstract::We report the experience from the Antiphospholipid Antibodies (aPL) Regional Consortium in northwest Italy, meant to support clinical research and foster collaboration among health professionals regarding the diagnosis and management of antiphospholipid syndrome (APS) patients. This cohort-study (APS Piedmont Cohort) ...
journal_title:Lupus
pub_type: 杂志文章
doi:10.1177/0961203312446974
更新日期:2012-06-01 00:00:00
abstract::The antiphospholipid syndrome (APS) is characterized by thrombosis and/or pregnancy morbidity in the presence of antiphospholipid antibodies (aPL). Among the thrombogenic mechanisms proposed, it has been suggested that aPL can stimulate tissue factor (TF) expression by endothelial cells (ECs) and monocytes. Moreover, ...
journal_title:Lupus
pub_type: 杂志文章,评审
doi:10.1191/0961203306lu2276rr
更新日期:2006-01-01 00:00:00
abstract::Despite strongly held opinions, a trustworthy scientific basis for most statements about autoimmunity, autoimmune diseases and assisted reproductive technologies (ART) does not exist. It is not likely that autoimmunity causes infertility, nor that patients with autoimmune diseases are unusually infertile. When careful...
journal_title:Lupus
pub_type: 杂志文章
doi:10.1191/0961203304lu2000oa
更新日期:2004-01-01 00:00:00
abstract::Involvement of the musculoskeletal system is common if not universal in the clinical course of systemic lupus erythematosus (SLE). Joint involvement on the whole does not cause major erosive disease, however, recent developments in musculoskeletal imaging show clearly the presence of significant bony and soft tissue i...
journal_title:Lupus
pub_type: 杂志文章
doi:10.1191/0961203303lu2021oa
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVE:The objective of this report is to assess the presence and viral load of JC polyomavirus (JCV) DNA in cerebrospinal fluid (CSF) and plasma from neuropsychiatric systemic lupus erythematosus (NPSLE) patients in comparison to controls and to investigate if different types of immunosuppressive treatments were co...
journal_title:Lupus
pub_type: 杂志文章
doi:10.1177/0961203312470977
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to determine whether the functional CD40 rs4810485 G/T polymorphism is associated with susceptibility to rheumatoid arthritis (RA) or with susceptibility to systemic lupus erythematosus (SLE). METHODS:A series of meta-analyses were conducted to test for association between the CD40 ...
journal_title:Lupus
pub_type: 杂志文章,meta分析
doi:10.1177/0961203315583543
更新日期:2015-10-01 00:00:00
abstract::Concerns regarding the safety and efficacy of immunization in patients with SLE have persisted for over 60 years, despite the increased risk of infection in these patients. There are many anecdotal case reports of SLE induction or exacerbation following immunization, but overall, these events seem to be very rare. Evi...
journal_title:Lupus
pub_type: 杂志文章,评审
doi:10.1177/0961203306069355
更新日期:2006-01-01 00:00:00
abstract::Obstetric antiphospholipid syndrome (APS) remains a clinical challenge for practitioners, with several controversial points that have not been answered so far. This Obstetric APS Task Force met on the 16th International Congress on Antiphospholipid Antibodies in Manchester, England, to discuss about treatment, diagnos...
journal_title:Lupus
pub_type: 杂志文章
doi:10.1177/0961203320954520
更新日期:2020-10-01 00:00:00
abstract::The SLICC/ACR damage index for SLE was developed to assess accumulated damage since the onset of the disease. The damage includes non-reversible changes in organs and systems affected by the disease process itself, its therapy, or inter-current illness. This paper describes the development of the damage index, its val...
journal_title:Lupus
pub_type: 杂志文章
doi:10.1191/096120399680411335
更新日期:1999-01-01 00:00:00
abstract::A girl with neuropsychiatric lupus demonstrated Parkinsonian features soon after commencing risperidone. The single photon emission computed tomography scan showed hyperperfusion of the basal ganglia. Symptoms abated with the addition of dopaminergic agents to immunosuppressive therapy. The literature on juvenile Park...
journal_title:Lupus
pub_type: 杂志文章
doi:10.1177/0961203307081421
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVES:The objective of this paper is to perform the cross-cultural validation of the French version of the LupusPRO, a disease-targeted patient-reported outcome measure, among systemic lupus erythematosus (SLE) patients in Canada. METHODS:The French version of the LupusPRO and the MOS SF-36 were administered; dem...
journal_title:Lupus
pub_type: 杂志文章
doi:10.1177/0961203314543921
更新日期:2014-12-01 00:00:00
abstract::Cardiac involvement in systemic lupus erythematosus (SLE) is well documented. The pericardium, myocardium and endocardium, as well as the coronary arteries, the valves and the conduction system can all be affected. While pericarditis is common, arrythmias are less frequently described.We present a 13-year-old male, wh...
journal_title:Lupus
pub_type: 杂志文章
doi:10.1177/0961203320974091
更新日期:2020-11-20 00:00:00