Increased aortic pulse wave velocity in middle aged women with systemic lupus erythematosus.

abstract：OBJECTIVE:The feed-forward loop of type I interferons (IFNs) production and subsequent immunopathology of systemic lupus erythematosus (SLE) has been hypothesised to be disrupted with inhibition of IFNα or type I IFN receptor subunit 1 (IFNAR). This systematic review and meta-analysis present the treatment efficacy and...

journal_title：Lupus

authors： Koh JWH,Ng CH,Tay SH

更新日期：2020-12-01 00:00:00

abstract：:The SLICC/ACR damage index for SLE was developed to assess accumulated damage since the onset of the disease. The damage includes non-reversible changes in organs and systems affected by the disease process itself, its therapy, or inter-current illness. This paper describes the development of the damage index, its val...

journal_title：Lupus

authors： Gladman DD,Urowitz MB

更新日期：1999-01-01 00:00:00

abstract：:Background Antimalarials (AMs) are widely used in the treatment of connective tissue diseases. Their main side effect is retinal damage, while heart disease has been described in isolated cases. The aim of this study is to systematically review the existing literature on AM-induced cardiomyopathy (AMIC). Methods The P...

journal_title：Lupus

authors： Tselios K,Deeb M,Gladman DD,Harvey P,Urowitz MB

更新日期：2018-04-01 00:00:00

abstract：:In search of markers of disease activity in patients with SLE we have investigated blood lymphocyte subsets from a large cohort of patient. Seventy-one patients were studied using a well-defined panel of fluorescent monoclonal antibodies which recognize the major T, B and NK lymphocyte subsets and activated cells. Flo...

journal_title：Lupus

authors： Erkeller-Yüsel F,Hulstaart F,Hannet I,Isenberg D,Lydyard P

更新日期：1993-08-01 00:00:00

abstract：:Severe systemic lupus erythematosus often requires the use of cyclophosphamide in women of reproductive age. As cyclophosphamide is generally avoided during pregnancy because of its teratogenic risk, its impact on fetal survival is poorly understood. This is a case series of lupus patients exposed to cyclophosphamide ...

journal_title：Lupus

authors： Clowse ME,Magder L,Petri M

更新日期：2005-01-01 00:00:00

abstract：:It is well known that women with systemic lupus erythematosus (SLE) who have antiphospholipid antibodies (aPL) are at increased risk for pregnancy loss. Additionally, other reproductive processes, such as unexplained infertility and implantation failure after in vitro fertilization and embryo transfer may be affected ...

journal_title：Lupus

authors： Balasch J,Cervera R

更新日期：2002-01-01 00:00:00

abstract：:Tumor necrosis factor alpha (TNF alpha) and interleukin-6 (IL-6) play a main role in inducing acute phase protein production by hepatocytes. This study describes the serum levels of TNF alpha and IL-6 in relation to serum levels of C-reactive protein (CRP) and alpha 1-acid glycoprotein (alpha 1AG) in three systemic lu...

journal_title：Lupus

authors： Meijer C,Huysen V,Smeenk RT,Swaak AJ

更新日期：1993-12-01 00:00:00

abstract：:Congenital heart block (CHB) is a syndrome of uncertain pathogenesis leading to cardiac conduction disturbances in the foetus and newborns. It has been proposed that maternal antibodies transmit immunological injury in the developing foetal heart, thus causing irreversible damage of the atrioventricular node, leading ...

journal_title：Lupus

authors： Sirén MK,Julkunen H,Kaaja R,Ekblad H,Koskimies S

更新日期：1999-01-01 00:00:00

abstract：:Only recently Bartonella species have been recognized as important human pathogens. Cat scratch disease (CSD), caused by infection with Bartonella henselae, shows a steady increase in the number of cases throughout the world. We report a case of an 18-year-old woman with systemic lupus erythematosus (SLE) who presente...

journal_title：Lupus

authors： Gaubitz M,Herrmann M,Shahin M,Schotte H,Willeke P,Domschke W

更新日期：2001-01-01 00:00:00

abstract：:Objective Genetic variants in FH (complement factor H) were reported to associate with susceptibility to systemic lupus erythematosus (SLE). This study proposed that the genetic defects of FH in the susceptibility and in the development of lupus nephritis might be different. Methods This study enrolled 334 lupus nephr...

journal_title：Lupus

authors： Tan M,Hao JB,Chu H,Wang FM,Song D,Zhu L,Yu F,Li YZ,Song Y,Zhao MH

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:We compared the 1997 update of the 1982 American College of Rheumatology (ACR-97) and the 2012 Systemic Lupus International Collaborating Clinics (SLICC-12) criteria, for earlier classification of systemic lupus erythematosus (SLE) in a multiethnic urban Asian SLE population. METHODS:Patients from a retrospe...

journal_title：Lupus

authors： Low ESH,Krishnaswamy G,Thumboo J

更新日期：2019-01-01 00:00:00

abstract：:Twelve systemic lupus erythematosus (SLE) patients with mild to moderate disease activity (SLEDAI of > or = 6 and on prednisolone < 0.5 mg/kg/day) were included in a prospective, randomized, double-blind, placebo-controlled pilot study for 24 weeks. Six were randomized to receive oral leflunomide and six received plac...

journal_title：Lupus

authors： Tam LS,Li EK,Wong CK,Lam CW,Szeto CC

更新日期：2004-01-01 00:00:00

abstract：:Proteinuria is a well-known risk factor for the progression of renal dysfunction in chronic kidney disease; however, its importance for estimating the prognosis of lupus nephritis requires verification. Korean adult patients with renal biopsy-diagnosed diffuse proliferative lupus nephritis who had undergone three or m...

journal_title：Lupus

authors： Koo HS,Kim S,Chin HJ

更新日期：2016-01-01 00:00:00

abstract：:We have previously shown that elevation of anticardiolipin antibodies (aCL) at the first prenatal visit is associated with increased fetal loss in normal pregnancy. The variation in aCL levels during normal pregnancy has not been established. To examine this question we measured IgG, IgM and IgA aCL levels five times ...

journal_title：Lupus

authors： Lynch AM,Rutledge JH,Stephens JK,Murphy JR,Marlar RA,Davila GH,Santos ME,Emlen W

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Antibodies to M-type phospholipase A2 receptor (a-PLA2R) have been identified in most patients with idiopathic membranous nephropathy, but the prevalence in membranous lupus nephritis (MLN) is still unclear. The objective of this study was to assess the prevalence of a-PLA2R antibodies in a large cohort of p...

journal_title：Lupus

authors： Garcia-Vives E,Solé C,Moliné T,Alvarez-Rios AM,Vidal M,Agraz I,Ordi-Ros J,Cortés-Hernández J

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Cognitive dysfunction (CD) is among the most common neuropsychiatric manifestations of systemic lupus erythematosus (SLE). There are two methods which have been used to detect CD in patients with SLE: traditional neuropsychological tests (NPT) and the Automated Neuropsychological Assessment Metrics (ANAM). B...

journal_title：Lupus

authors： Adhikari T,Piatti A,Luggen M

更新日期：2011-10-01 00:00:00

abstract：:The aim of this study was to use transthoracic Doppler echocardiographic (TTE) imaging methods to identify cardiac dysfunction, an indicator of subclinical atherosclerosis in asymptomatic systemic lupus erythematosus (SLE) patients in terms of cardiac effects. This study involved 80 patients: a study group (n = 50) an...

journal_title：Lupus

authors： Barutcu A,Aksu F,Ozcelik F,Barutcu CA,Umit GE,Pamuk ON,Altun A

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to analyse autoantibodies' titres modulation during belimumab treatment in 50 patients with systemic lupus erythematosus (SLE). METHODS:Sera were collected at belimumab start (T0) and every six months until the 24th month. Disease activity index (SLEDAI-2K) was analysed at eve...

journal_title：Lupus

authors： Cavazzana I,Kumar R,Pozzari C,Ottaviani R,Fredi M,Piantoni S,Andreoli L,Tincani A,Franceschini F

更新日期：2019-08-01 00:00:00

abstract：:The objective of this study was to determine the HLA class II associations of the anticardiolipin (aCL) and anti-beta2GPI (abeta2GPI) antibodies in a large series of European patients with systemic lupus erythematosus (SLE). A cohort of 577 European SLE patients was enrolled. aCL and abeta2GPI were measured by ELISA m...

journal_title：Lupus

authors： Galeazzi M,Sebastiani GD,Tincani A,Piette JC,Allegri F,Morozzi G,Bellisai F,Scorza R,Ferrara GB,Carcassi C,Font J,Passiu G,Smolen J,Papasteriades C,Houssiau F,Nebro AF,Ramon Garrido ED,Jedryka-Goral A,Marcolongo R

更新日期：2000-01-01 00:00:00

abstract：:Abnormalities of the lipid profile partly explain the atherogenic tendency of systemic lupus erythematosus but the picture is unclear in thrombotic primary antiphospholipid syndrome (PAPS). Herein we compare the lipid profile, high-density lipoprotein (HDL), low-density lipoprotein (LDL), total cholesterol (CHO), apol...

journal_title：Lupus

authors： Ames PR,Matsuura E,Batuca JR,Ciampa A,Lopez LL,Ferrara F,Iannaccone L,Alves JD

更新日期：2010-05-01 00:00:00

abstract：:In 2012, the Systemic Lupus International Collaborating Clinics (SLICC) group published a new set of classification criteria for systemic lupus erythematosus (SLE). Studies applying these criteria to real-life scenarios have found either equal or greater sensitivity and equal or lower specificity to the 1997 ACR class...

journal_title：Lupus

authors： Ungprasert P,Sagar V,Crowson CS,Amin S,Makol A,Ernste FC,Osborn TG,Moder KG,Niewold TB,Maradit-Kremers H,Ramsey-Goldman R,Chowdhary VR

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Palisaded neutrophilic and granulomatous dermatitis (PNGD) is a commonly occurring condition related to systemic autoimmune disease. It is characterized histopathologically by a distinct pattern of granulomatous inflammation in the presence or absence of leukocytoclastic vasculitis. The properties of granulo...

journal_title：Lupus

authors： Terai S,Ueda-Hayakawa I,Nguyen CTH,Ly NTM,Yamazaki F,Kambe N,Son Y,Okamoto H

更新日期：2018-12-01 00:00:00

abstract：:Corrigendum to A North American perspective of content and quality of websites in the English language on childhood-onset lupus erythematosus by C Cutler et al. Published in Lupus (2018) 27, 762-770. DOI: 10.1177/0961203317746246 . The authors wish to highlight the following correction. The subheading in Table 5 shoul...

journal_title：Lupus

authors：

更新日期：2018-12-01 00:00:00

abstract：:The objective of this article was to evaluate whether serum uric acid (SUA) correlates with arterial stiffness and inflammation markers in a cohort of women with systemic lupus erythematosus (SLE) without overt atherosclerotic cardiovascular diseases, who attended a community hospital. One hundred and two women with S...

journal_title：Lupus

authors： Sabio JM,Vargas-Hitos JA,Mediavilla JD,Navarrete-Navarrete N,Zamora-Posadas M,Pérez-Vicente S,Hidalgo-Tenorio C,Díaz-Chamorro A,Jáimez L,Jiménez-Alonso J,Grupo Lupus Virgen de las Nieves.

更新日期：2010-04-01 00:00:00

abstract：:Skin involvement in systemic lupus erythematosus (SLE) occurs in varied forms. Lupus erythematosus tumidus (LET) is not known to occur with SLE. In our patient presented below, LET occurred in a patient with SLE. Some of the lesions progressed to scarring discoid lesions, while others responded very well to hydoxychlo...

journal_title：Lupus

authors： Jolly M,Laumann AE,Shea CR,Utset TO

更新日期：2004-01-01 00:00:00

abstract：:Gastrointestinal manifestations of systemic lupus erythematosus (SLE) are common, occurring in about 50% of cases. They are usually mild, in the form of mouth ulcers, nausea, heartburn and mild abdominal pain, but they can be severe in cases of gastrointestinal vasculitis. In this report we describe an unusual combina...

journal_title：Lupus

authors： Bedaiwi M,Alkubeyyer MA,Al Arfaj AS

更新日期：2014-02-01 00:00:00

abstract：:Our objective was to investigate whether quality of life in systemic lupus erythematosus (SLE) differs across ethnoracial groups and to identify factors that may explain race-related differences. Self-administered questionnaire data from 335 White, 40 Black, and 30 Asian women with SLE were obtained from a multi-cente...

journal_title：Lupus

authors： Devins GM,Edworthy SM

更新日期：2000-01-01 00:00:00

abstract：:Neonatal lupus erythematosus (NLE) is an uncommon condition usually associated with maternal anti-Ro autoantibodies. The cutaneous lesions of NLE are usually transient, disappearing about six months after birth, but telangiectasia is a rare complication of NLE which persists. Telangiectasias are small focal red macule...

journal_title：Lupus

authors： Guinovart RM,Vicente A,Rovira C,Suñol M,González-Enseñat MA

更新日期：2012-04-01 00:00:00

abstract：:Neonatal antiphospholipid syndrome (neonatal APS) seems to be exceedingly rare, as the antiphospholipid antibodies (aPL) related thrombosis in the neonatal period. The pathogenesis of perinatal aPL related thrombosis may be explained both by the transplacental passage of the maternal antibodies and by the production o...

journal_title：Lupus

authors： De Carolis MP,Salvi S,Botta A,Cocca C,Garufi C,Lanzone A,De Carolis S

更新日期：2015-03-01 00:00:00

abstract：:Cytomegalovirus (CMV) is particularly dangerous in systemic lupus erythematosus (SLE), being a problem both for the differential diagnosis with disease flare and for the management of SLE flare with immunosuppressive drugs. We report on four cases of SLE with concomitant CMV infection, having some common clinical and ...

journal_title：Lupus

authors： Sebastiani GD,Iuliano A,Canofari C,Bracci M

更新日期：2019-03-01 00:00:00