Abstract:
:Neuronal plasticity depends on plasma membrane Ca(2+) influx, resulting in activity-dependent gene transcription. Calmodulin (CaM) activated by Ca(2+) initiates the nuclear events, but how CaM makes its way to the nucleus has remained elusive. Ma et al. now show that CaMKIIγ transports CaM from cell surface Ca(2+) channels to the nucleus.
journal_name
Celljournal_title
Cellauthors
Malik ZA,Stein IS,Navedo MF,Hell JWdoi
10.1016/j.cell.2014.09.023subject
Has Abstractpub_date
2014-10-09 00:00:00pages
235-7issue
2eissn
0092-8674issn
1097-4172pii
S0092-8674(14)01172-6journal_volume
159pub_type
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