Integration of clinical data collected at different times for virtual surgery in single ventricle patients: a case study.

abstract：:In this paper, we present the application of a semi-global inverse method for determining material parameters of biological tissues. The approach is based on the successive response surface method, and is illustrated by fitting constitutive parameters to two nonlinear anisotropic constitutive equations, one for aortic...

journal_title：Annals of biomedical engineering

authors： Einstein DR,Freed AD,Stander N,Fata B,Vesely I

更新日期：2005-12-01 00:00:00

abstract：:Observing microscopic specimens is often useful in studies of cellular interaction with a vascular wall. We have developed an in vitro side-view flow chamber that permits observations from the side of the cell's contact with various adhesive surfaces under dynamic flow conditions. This side-view flow chamber consists ...

journal_title：Annals of biomedical engineering

authors： Cao J,Usami S,Dong C

更新日期：1997-05-01 00:00:00

abstract：:It is proposed that the maximum in cuff pressure oscillations during oscillometry is due to the buckling of the brachial artery under a cuff. This theory is investigated by means of a mathematical model of oscillatometry that includes the mechanics of the occlusive arm cuff, the arterial pressure pulse waveform, and t...

journal_title：Annals of biomedical engineering

authors： Drzewiecki G,Hood R,Apple H

更新日期：1994-01-01 00:00:00

abstract：:Opportunities to provide clinical immersion experiences to bioengineering undergraduate students have expanded over the last several years. These programs allow students to observe the clinical environment in order to better understand workflow processes, the context in which medical equipment is used, and identify un...

journal_title：Annals of biomedical engineering

authors： Kotche M,Felder AE,Wilkens K,Stirling S

更新日期：2020-09-01 00:00:00

abstract：:Skeletal muscles can be injured by their own contractions. Such contraction-induced injury, often accompanied by delayed onset of muscle soreness, is a leading cause of the loss of mobility in the rapidly increasing population of elderly people. Unlike other types of muscle injuries which hurt almost exclusively those...

journal_title：Annals of biomedical engineering

authors： Givli S

更新日期：2015-02-01 00:00:00

abstract：:The temporal and spatial distribution of coronary blood flow, pressure, and volume are determined by the branching pattern and three-dimensional (3-D) geometry of the coronary vasculature, and by the mechanics of heart wall and vascular tone. Consequently, a realistic simulation of coronary blood flow requires, as a f...

journal_title：Annals of biomedical engineering

authors： Kaimovitz B,Lanir Y,Kassab GS

更新日期：2005-11-01 00:00:00

abstract：:An endovascular technique using a stent has been developed and successfully applied in the treatment of wide neck aneurysms. A stent can facilitate thrombosis in the aneurysm pouch while maintaining biocompatible passage of the parent artery. Insertion of the stent changes the flow characteristics inside the aneurysm ...

journal_title：Annals of biomedical engineering

authors： Rhee K,Han MH,Cha SH

更新日期：2002-07-01 00:00:00

abstract：:Recent studies suggest that vortex ring formation during left ventricular (LV) rapid filling is an optimized mechanism for blood transport, and that the volume of the vortex ring is an important measure. However, due to lack of quantitative methods, the volume of the vortex ring has not previously been studied. Lagran...

journal_title：Annals of biomedical engineering

authors： Töger J,Kanski M,Carlsson M,Kovács SJ,Söderlind G,Arheden H,Heiberg E

更新日期：2012-12-01 00:00:00

abstract：:In this paper, we aim to establish a new mathematical model that relates pulse wave velocity (PWV) to blood pressure (BP) for continuous and noninvasive BP measurement. For the first time, we derive an ordinary differential equation (ODE) expressing the fundamental relation between BP, elastic modulus G and PWV. The g...

journal_title：Annals of biomedical engineering

authors： Chen Y,Wen C,Tao G,Bi M,Li G

更新日期：2009-11-01 00:00:00

abstract：:It is well known that neutrophils take much longer to traverse the pulmonary capillary bed than erythrocytes, and this is likely due to differences in the structure and rheology of the cells. In this study, we simulate the transit of a neutrophil in a capillary using a Newtonian drop model and a viscoelastic drop mode...

journal_title：Annals of biomedical engineering

authors： Zhou C,Yue P,Feng JJ

更新日期：2007-05-01 00:00:00

abstract：:Traditionally, measurement of pulmonary O2 uptake uses mass balance of N2 to correct for differences between inspired and expired volume (V) due to temperature (T) and relative humidity (RH). Often during anesthesia, N2 balance cannot be invoked due to high inspired O2 fraction (FIO2) or nonsteady state conditions. Th...

journal_title：Annals of biomedical engineering

authors： Breen PH

更新日期：2000-09-01 00:00:00

abstract：:In this study we present a novel, robust method to couple finite element (FE) models of cardiac mechanics to systems models of the circulation (CIRC), independent of cardiac phase. For each time step through a cardiac cycle, left and right ventricular pressures were calculated using ventricular compliances from the FE...

journal_title：Annals of biomedical engineering

authors： Kerckhoffs RC,Neal ML,Gu Q,Bassingthwaighte JB,Omens JH,McCulloch AD

更新日期：2007-01-01 00:00:00

abstract：:A comparison was made between turbulence calculated by subtracting an ensemble average from the instantaneous velocity and calculations made with a high pass digital filter. Velocity was measured with a laser Doppler anemometer in vitro in the region of a normal porcine aortic valve and in patients with a hot film ane...

journal_title：Annals of biomedical engineering

authors： Walburn FJ,Sabbah HN,Stein PD

更新日期：1983-01-01 00:00:00

abstract：:"Smart" drug delivery systems should be selective and effective to ensure drug administration at the right time, at the right dosage, and anywhere in the body. Among the several administration routes and delivery systems that have been proposed, one of the most effective and promising is based on microfabricated parti...

journal_title：Annals of biomedical engineering

authors： Decuzzi P,Lee S,Decuzzi M,Ferrari M

更新日期：2004-06-01 00:00:00

abstract：:A novel in vitro culture system of organotypic human skin explants interfacing with external fixator pins is presented. The system was used to observe changes in skin morphology on the skin at the pin interface. To evaluate the performance of this novel system, histological analysis of human skin explants cultured for...

journal_title：Annals of biomedical engineering

authors： Peramo A,Marcelo CL,Goldstein SA,Martin DC

更新日期：2009-02-01 00:00:00

abstract：:High-frequency ventilation (HFV) has not one but several histories. Proceeding along largely independent pathways are techniques using frequencies of 1-5 Hz and techniques using 10-40 Hz, the former being introduced by Sjostrand in 1971, the latter by Lunkenheimer in 1972. It was nearly ten years before it was recogni...

journal_title：Annals of biomedical engineering

authors： Bryan AC

更新日期：1984-01-01 00:00:00

abstract：:Hemodynamic forces are known to be able to induce an inflammatory phenotype in endothelial cells (ECs). The EC glycocalyx (GCX) is a dynamic structure which is regulated in response to different stimuli and hypothesized as an important contributor to the mechanotransduction of wall shear stresses (WSS). In this work, ...

journal_title：Annals of biomedical engineering

authors： Cooper S,McDonald K,Burkat D,Leask RL

更新日期：2017-09-01 00:00:00

abstract：:It is widely recognized that the bacteria sequestered in a biofilm on a medical implant are much more resistant to antibiotics than their planktonic counterparts. Recent studies have shown that application of antibiotic along with low power ultrasound significantly increases the killing of planktonic bacteria by the a...

journal_title：Annals of biomedical engineering

authors： Qian Z,Sagers RD,Pitt WG

更新日期：1997-01-01 00:00:00

abstract：:Biologically active heart valves (tissue engineered and recellularized tissue-derived heart valves) have the potential to offer enhanced function when compared to current replacement value therapies since they can possibly remodel, and grow to meet the needs of the patient, and not require chronic medication. However,...

journal_title：Annals of biomedical engineering

authors： Hildebrand DK,Wu ZJ,Mayer JE Jr,Sacks MS

更新日期：2004-08-01 00:00:00

abstract：:Three animal models were evaluated in this study involving head impacts of the rat, including the Marmarou drop-weight and two momentum-exchange techniques. In series 1, 36 Wistar rats were hit on the side of the free-moving head using Marmarou's 450 g impact mass at 4.4, 5.4, and 6.3 m/s. Head acceleration was measur...

journal_title：Annals of biomedical engineering

authors： Viano DC,Hamberger A,Bolouri H,Säljö A

更新日期：2012-01-01 00:00:00

abstract：:Impedance data, e.g., system responses, from perturbing small amplitude applied sinusoid signals of near DC to high kilohertz frequencies, give chemical information. Analysis of frequency-dependent imaginary and real impedance proceeds from equivalent analog circuit elements to chemical and physical significance deter...

journal_title：Annals of biomedical engineering

authors： Buck RP

更新日期：1992-01-01 00:00:00

abstract：:The combination of gene therapy and chemotherapy has showed increased therapeutic efficacy in the treatment of cancers, but it is not well investigated about the actual coordination pattern between therapeutic gene and chemical drug. In this work, p53/BPEI-β-CD/AD-dox complex was fabricated and employed to investigate...

journal_title：Annals of biomedical engineering

authors： Xie B,Peng J,Wang S,Zhang X,Nie H

更新日期：2016-11-01 00:00:00

abstract：:Continued progress in the field of Brain Interface (BI) research has encouraged the rapid expansion of the BI community over the last two decades. As the number of BI researchers and organizations steadily increases, newer and more advanced technologies are constantly produced, evaluated, and reported. Though the BI c...

journal_title：Annals of biomedical engineering

authors： Jackson MM,Mason SG,Birch GE

更新日期：2006-05-01 00:00:00

abstract：:Irreversible electroporation (IRE), is a new non-thermal tissue ablation technology in which brief high electric field pulses are delivered across the target tissue to induce cell death by irreversible permeabilization of the cell membrane. A deficiency of conventional IRE is that the ablation zone is relatively small...

journal_title：Annals of biomedical engineering

authors： Lv Y,Yao C,Rubinsky B

更新日期：2019-07-01 00:00:00

abstract：:Typical inverse dynamics approaches to the calculation of muscle, ligament, and joint contact forces are based on a step-wise solution of the equations of motion. This approach is therefore limited in its ability to provide insight as to the muscular, ligamentous, and articular interactions that create joint stability...

journal_title：Annals of biomedical engineering

authors： Cleather DJ,Bull AM

更新日期：2011-07-01 00:00:00

abstract：:A goal of the Human Research Program at National Aeronautics and Space Administration (NASA) is to analyze and mitigate the risk of occupant injury due to dynamic loads. Experimental tests of human subjects and biofidelic anthropomorphic test devices provide valuable kinematic and kinetic data related to injury risk e...

journal_title：Annals of biomedical engineering

authors： Gaewsky JP,Jones DA,Ye X,Koya B,McNamara KP,Gayzik FS,Weaver AA,Putnam JB,Somers JT,Stitzel JD

更新日期：2019-02-01 00:00:00

abstract：:Rapid screening of biomarkers, with high specificity and accuracy, is critical for many point-of-care diagnostics. Microfluidics, the use of microscale channels to manipulate small liquid samples and carry reactions in parallel, offers tremendous opportunities to address fundamental questions in biology and provide a ...

journal_title：Annals of biomedical engineering

authors： Ng E,Chen K,Hang A,Syed A,Zhang JX

更新日期：2016-04-01 00:00:00

abstract：:This study was aimed at developing a physical model, supported by experimental observations, to describe the formation and growth of microbubbles seen in patients with mitral mechanical heart valves (MHV). This phenomenon, often referred to as high intensity transient signals (HITS), appears as bright, intense, high-v...

journal_title：Annals of biomedical engineering

authors： Rambod E,Beizaie M,Shusser M,Milo S,Gharib M

更新日期：1999-11-01 00:00:00

abstract：:This study aimed to quantify the elongation patterns of the collateral ligaments following TKA during functional activities of daily living. Using mobile video-fluoroscopy to capture radiographic images of the knee in a group of six patients, each with an ultra-congruent knee implant, tibiofemoral kinematics were reco...

journal_title：Annals of biomedical engineering

authors： Hosseini Nasab SH,Smith CR,Schütz P,Damm P,Trepczynski A,List R,Taylor WR

更新日期：2020-04-01 00:00:00

abstract：:The bending stiffness of a phospholipid bilayer (Kc) was measured by forming thin bilayer cylinders (tethers) from giant phospholipid vesicles. Based on the balance of forces, the tether force was expected to be proportional to the square root of the membrane tension, with a constant of proportionality containing Kc. ...

journal_title：Annals of biomedical engineering

authors： Heinrich V,Waugh RE

更新日期：1996-09-01 00:00:00