Remission Time after Rituximab Treatment for Autoimmune Bullous Disease: A Proposed Update Definition.

abstract：:To reduce pruritus and colonization with Staphylococcus aureus, textiles containing silver are increasingly used as therapeutic option for patients with atopic dermatitis (AD). While wearing such textiles, the contained silver is in close contact with the patient's skin. The silver serves two purposes: to reduce bacte...

journal_title：Skin pharmacology and physiology

authors： Daeschlein G,Assadian O,Arnold A,Haase H,Kramer A,Jünger M

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Ultraviolet (UV) irradiation is well known to promote inflammation and pigmentation of skin. UVB mainly affects dermatitis and pigmentation. Coffee contains a number of polyphenols, such as caffeic acid (CA) and chlorogenic acid (CGA) but their in vivo bioactivity for photobiology remains unclear. METHODS:C...

journal_title：Skin pharmacology and physiology

authors： Yamate Y,Hiramoto K,Sato EF

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Reactive oxygen species generated by ultraviolet light result in photocarcinogenic and photoaging changes in the skin. Antioxidants protect the skin from these insults. OBJECTIVE:The aim of this study was to determine the ex vivo ascorbic acid penetration and its degradation in the skin after its topical ap...

journal_title：Skin pharmacology and physiology

authors： Leveque N,Muret P,Makki S,Mac-Mary S,Kantelip JP,Humbert P

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:The Cosmetics Europe ADME Task Force is developing in vitro and in silico tools for predicting skin and systemic concentrations after topical application of cosmetic ingredients. There are conflicting reports as to whether the freezing process affects the penetration of chemicals; therefore, we evaluated whe...

journal_title：Skin pharmacology and physiology

authors： Jacques-Jamin C,Duplan H,Rothe H,Vaillant O,Eilstein J,Grégoire S,Cubberley R,Lange D,Ellison C,Klaric M,Hewitt N,Schepky A

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:The vitamin D endocrine system, besides multiple other functions, regulates aging in many tissues, including the skin. It protects the skin against the hazardous effects of many skin age-inducing agents, including ultraviolet radiation. Thus, in the present study we aimed to investigate the relationship betw...

journal_title：Skin pharmacology and physiology

authors： Dawoud NM,Bakry OA,Shoeib MA,Ismael HN

更新日期：2016-01-01 00:00:00

abstract：:Brian Barry published over 300 research articles across topics ranging from colloid science, vasoconstriction and the importance of thermodynamics in dermal drug delivery to exploring the structure and organisation of the stratum corneum barrier lipids and numerous strategies for improving topical and transdermal drug...

journal_title：Skin pharmacology and physiology

authors： Williams AC

更新日期：2013-01-01 00:00:00

abstract：AIM AND METHODS:Drug development in dermatotherapy and also development of transdermal therapeutic systems (TTS) demand high-predictive in vitro models to estimate drug levels in skin and systemic uptake. Here we compare three ready-to-use models, reconstructed human epidermis, split porcine skin and the perfused porci...

journal_title：Skin pharmacology and physiology

authors： Mahmoud A,Haberland A,Dürrfeld M,Heydeck D,Wagner S,Schafer-Korting M

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Sesquiterpenes in Curcuma aeruginosa Roxb. inhibit steroid 5α-reductase and dihydrotestosterone production, and reverse androgenic alopecia. This study sought to show that a high sesquiterpene C. aeruginosa extract (CA-ext) retards axillary hair growth in women. METHODS:Thirty women (age 20-52 years) were r...

journal_title：Skin pharmacology and physiology

authors： Srivilai J,Nontakhot K,Nutuan T,Waranuch N,Khorana N,Wisuthiprot W,Scholfield CN,Champachaisri K,Ingkaninan K

更新日期：2018-01-01 00:00:00

abstract：:Neoplastic skin lesions are multifocal, diffuse skin infiltrations of particular relevance in the differential diagnosis of ulcerative, nodular, or crusting skin lesions. Nonmelanoma skin cancers (NMSCs), namely, basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and also actinic keratosis (AK), are the most c...

journal_title：Skin pharmacology and physiology

authors： Fernandes AR,Santos AC,Sanchez-Lopez E,Kovačević AB,Espina M,Calpena AC,Veiga FJ,Garcia ML,Souto EB

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND/AIMS:Keloids result from aberrations in the normal wound healing cascade and can lead to pruritus, contractures and pain. The underlying mechanisms of excessive scarring are not yet understood, and most therapeutic strategies remain unsatisfactory. Psoriasin (S100A7) and koebnerisin (S100A15) are released by...

journal_title：Skin pharmacology and physiology

authors： Gauglitz GG,Bureik D,Zwicker S,Ruzicka T,Wolf R

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIMS:Atopic dermatitis (AD) is a common disease in infancy, for which topical steroids are the first-line therapy but have side effects. Innovative approaches are needed to reduce the burden of AD and corticosteroid usage in infants. METHODS:The once-daily consumption of heat-treated probiotic Lactobacillus...

journal_title：Skin pharmacology and physiology

authors： Yan DC,Hung CH,Sy LB,Lue KH,Shih IH,Yang CY,Chen LC,Sun HL,Lee MS,Chambard J,Tanguy J,Hughes-Formella B,Nutten S,Blanchard C

更新日期：2019-01-01 00:00:00

abstract：:Despite its remarkable barrier function, the skin remains an attractive site for systemic drug delivery given its easy accessibility, large surface area and the possibility to bypass the gastrointestinal tract and the liver and so modify drug absorption kinetics. The pioneering work of Scheuplein, Higuchi and others i...

journal_title：Skin pharmacology and physiology

authors： Perumal O,Murthy SN,Kalia YN

更新日期：2013-01-01 00:00:00

abstract：:Biogenic amines are potential irritants e.g. in fish-, meat-, milk- and egg-processing professions like cooks, butchers and bakers. The aim of this study was to test the irritative and barrier-disrupting properties of the biogenic amines ammonium hydroxide (AM), dimethylamine (DMA) and trimethylamine (TMA). A repeated...

journal_title：Skin pharmacology and physiology

authors： Fluhr JW,Kelterer D,Fuchs S,Kaatz M,Grieshaber R,Kleesz P,Elsner P

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND/AIMS:The skin has become very attractive as a route for drug administration. Optimization of topical drug formulations by the addition of penetration enhancers may facilitate the passage of drugs through the stratum corneum. METHODS:In this paper, the skin penetration effect of phytosphingosine and 9 derive...

journal_title：Skin pharmacology and physiology

authors： Veryser L,Boonen J,Taevernier L,Guillaume J,Risseeuw M,Shah SN,Roche N,Van Calenbergh S,De Spiegeleer B

更新日期：2015-01-01 00:00:00

abstract：:Despite sensitive skin being highly prevalent, no consensus on the definition and pathomechanism of sensitive skin exists. Here we report the results of a systematic literature review of diagnostic methods for sensitive skin at clinical, histological and biophysical levels. A systematic search revealed 27 out of 1,701...

journal_title：Skin pharmacology and physiology

authors： Richters R,Falcone D,Uzunbajakava N,Verkruysse W,van Erp P,van de Kerkhof P

更新日期：2015-01-01 00:00:00

abstract：:Along with antibiotics, antihistamines are the most widely used systemic drugs in dermatology. This is attributable to the major role played by histamine in common diseases such as urticaria and atopic eczema. Of the currently recognised four subtypes of G protein-coupled histamine receptors, only the H1 and H2 subtyp...

journal_title：Skin pharmacology and physiology

authors： Greaves MW

更新日期：2005-09-01 00:00:00

abstract：:Oral ingestion of collagen peptides (CP) has long been suggested to exert beneficial effects on the skin, but the molecular events induced by CP on the skin remain unclear. Here, we investigated the effects of oral CP administration on gene expression in hairless mouse skin and of prolyl-hydroxyproline (Pro-Hyp), a co...

journal_title：Skin pharmacology and physiology

authors： Le Vu P,Takatori R,Iwamoto T,Akagi Y,Satsu H,Totsuka M,Chida K,Sato K,Shimizu M

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIMS:Advanced glycation end products, which are linked to both aging and hyperglycemia, cause marked functional and structural alterations in human skin. Though it is well known that the metabolism of glucose is closely associated with that of fatty acid (FA), sharing the same energy-yielding reaction pathwa...

journal_title：Skin pharmacology and physiology

authors： Yokota M,Tokudome Y

更新日期：2016-01-01 00:00:00

abstract：:Cutaneous irritation presents a major health problem with serious social and occupational impact. The interaction between an irritant and the human skin depends on multiple factors: the intrinsic properties and the nature of the irritant itself, and specific individual- and environment-related variables. The main path...

journal_title：Skin pharmacology and physiology

authors： Fluhr JW,Darlenski R,Angelova-Fischer I,Tsankov N,Basketter D

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND/AIMS:Extrinsic and intrinsic skin aging is subject to constant remodeling and degradation processes, primarily in components of the extracellular matrix. While collagen fibers thin out during the aging process, the amorphous elastin fibers accumulate. These are essential formative components of the dermis. S...

journal_title：Skin pharmacology and physiology

authors： Czekalla C,Schönborn KH,Döge N,Jung S,Darvin ME,Lademann J,Meinke MC

更新日期：2017-01-01 00:00:00

abstract：:Talarozole is a new highly potent and selective azole derivative which inhibits cytochrome-P450-dependent all-trans-retinoic acid catabolism. It is in clinical development for the treatment of psoriasis and acne. However, no local pharmacokinetic data on the diffusion behaviour of talarozole in the skin itself are ava...

journal_title：Skin pharmacology and physiology

authors： Baert B,De Spiegeleer B

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND/AIMS:Wound healing is a complex regeneration process involving the degradation and reassembly of connective tissues and skin layers. Previous studies have shown that pH plays a significant role in both the direct and indirect regulation of cellular processes in the wound, which, in turn, affect the wound heal...

journal_title：Skin pharmacology and physiology

authors： Park G,Oh DS,Kim YU,Park MK

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVES:Retinoic acid (RA) and benzoyl peroxide (BP) were studied, comparing their keratolytic efficacy and water barrier disruption to that of salicylic acid (SA), a well-established keratolytic, under similar conditions. PATIENTS/METHODS:Six volunteers were included in this blinded study. Eleven randomized test s...

journal_title：Skin pharmacology and physiology

authors： Waller JM,Dreher F,Behnam S,Ford C,Lee C,Tiet T,Weinstein GD,Maibach HI

更新日期：2006-01-01 00:00:00

abstract：AIM:The purpose of this study was to characterise C₆₀-poly(vinylpyrrolidone) (PVP) dispersions, to analyse the cutaneous absorption of fullerenes as well as to evaluate whether UVA radiation (UVA-R) could modify its permeation profile. METHODS:Dispersions were characterised according to their pH, particle size, zeta p...

journal_title：Skin pharmacology and physiology

authors： Souto GD,Pohlmann AR,Guterres SS

更新日期：2015-01-01 00:00:00

abstract：:The sirtuins are a family of proteins that comprise class III of the histone deacetylases. These NAD+-dependent proteins have been found to be intricately involved in a variety of important and skin-relevant cellular functions and processes, including aging, UV damage response, oxidative stress, and wound repair. In a...

journal_title：Skin pharmacology and physiology

authors： Garcia-Peterson LM,Wilking-Busch MJ,Ndiaye MA,Philippe CGA,Setaluri V,Ahmad N

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:About 50% of the sun's radiation arriving on earth is visible light (VIS). For a long time, its effects on human health have not been fully investigated. But recently, the influence of VIS has gained more attention, especially regarding skin physiology. Studies showed various effects, many of them harmful, c...

journal_title：Skin pharmacology and physiology

authors： Wabnik M,Kockott D,Garbe B,Theek C,Heinrich U,Tronnier H,Braun N

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION:Flare reactions arise due to the release of vasodilators from sensory nerves caused by antidromic transmission of action potentials after the induction of itch. OBJECTIVE:We investigated the link between flare and itch using 3 models of itch. METHODS:Skin provocations with histamine, capsaicin, and cowha...

journal_title：Skin pharmacology and physiology

authors： Lehmann S,Deuring E,Weller K,Scheffel J,Metz M,Maurer M,Hawro T

更新日期：2020-01-01 00:00:00

abstract：:The human skin barrier is an important part of the skin's intactness and its functionality is a precondition for healthy skin. Ingredients in cosmetic formulations, especially penetration enhancers, can influence this barrier function as they transport active agents into deeper skin layers. In this study different cos...

journal_title：Skin pharmacology and physiology

authors： Heinrich K,Heinrich U,Tronnier H

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The use of antioxidants has become a common practice in the development of antiaging cosmetics. OBJECTIVE:The aim of this study was to evaluate the clinical efficacy of cosmetic formulations containing lycopene and melatonin antioxidants. METHOD:Thirty-six healthy women from 32 to 65 years were enrolled in...

journal_title：Skin pharmacology and physiology

authors： Marchena AM,Franco L,Romero AM,Barriga C,Rodríguez AB

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Research has revealed new insights into the pathogenesis of psoriasis, leading to new therapeutic options. So far the order of changes in the pathogenesis of psoriasis is unclear. The responses to cutaneous leukotriene B4 (LTB4) application have been studied in the past as an in vivo model for inflammation. ...

journal_title：Skin pharmacology and physiology

authors： Hendriks AG,Keijsers RR,Seyger MM,van de Kerkhof PC,van Erp PE

更新日期：2014-01-01 00:00:00