Abstract：
:In mouse intestinal tumors induced by the inhibition of APC, the restoration of APC function causes complete tumor regression with normal differentiation and return of stem cell function irrespective of whether tumors also carried mutations in Kras and p53. These findings by Dow et al. validate the Wnt pathway as an exquisite target for intervention.
journal_name
Celljournal_title
Cellauthors
Krimpenfort P,Berns Adoi
10.1016/j.cell.2015.06.008subject
Has Abstractpub_date
2015-06-18 00:00:00pages
1494-6issue
7eissn
0092-8674issn
1097-4172pii
S0092-8674(15)00691-1journal_volume
161pub_type
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