Proliferation at the heart of preadolescence.

Abstract:

:Cardiomyocytes, the cells of the heart muscle, lose nearly all of their proliferative capacity after birth, limiting the heart's ability to regenerate. Naqvi et al. now identify a transient burst of cardiomyocyte proliferation during preadolescence, driven by a thyroid hormone surge, with therapeutic implications for congenital and acquired heart diseases.

journal_name

Cell

journal_title

Cell

authors

Palpant NJ,Murry CE

doi

10.1016/j.cell.2014.04.025

subject

Has Abstract

pub_date

2014-05-08 00:00:00

pages

765-7

issue

4

eissn

0092-8674

issn

1097-4172

pii

S0092-8674(14)00543-1

journal_volume

157

pub_type

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