Compensatory stepping in Parkinson's disease is still a problem after deep brain stimulation randomized to STN or GPi.

abstract：:A description of healthy and pathological brain dynamics requires an understanding of spatiotemporal patterns of neural activity and characteristics of its propagation between interconnected circuits. However, the structure and modulation of the neural activation maps underlying these patterns and their propagation re...

journal_title：Journal of neurophysiology

authors： Hazra A,Rosenbaum R,Bodmann B,Cao S,Josić K,Žiburkus J

更新日期：2012-07-01 00:00:00

abstract：:In experiments on slices (from 100- to 150-g Sprague-Dawley rats) kept at 33 degreesC, we studied the effects of brief hypoxia (2-3 min) on CA1 neurons. In whole cell recordings from submerged slices, with electrodes containing only KMeSO4 and N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid, and in the presence of...

journal_title：Journal of neurophysiology

authors： Erdemli G,Xu YZ,Krnjević K

更新日期：1998-11-01 00:00:00

abstract：:1. Transmission at electrical synapses is modulated by a variety of physiological signals, and this modulation is a potentially general mechanism for regulating signal integration in neural circuits and networks. In the outer plexiform layer of the retina, modulation of horizontal-cell electrical coupling by dopamine ...

journal_title：Journal of neurophysiology

authors： McMahon DG,Brown DR

更新日期：1994-11-01 00:00:00

abstract：:1. A quantitative analysis of facilitation during the kindling stimulation to the amygdala was conducted by measuring the area between the excitatory potential and the baseline in the averaged tetanic response recorded at the entorhinal cortex. The changes in facilitation were then compared with the development of ele...

journal_title：Journal of neurophysiology

authors： Matsuura S,Hirayama K,Murata R

更新日期：1993-08-01 00:00:00

abstract：:The pharynx of C. elegans is a rhythmically active muscle that pumps bacteria into the gut of the nematode. This activity is maintained by action potentials, which qualitatively bear a resemblance to vertebrate cardiac action potentials. Here, the ionic basis of the resting membrane potential and pharyngeal action pot...

journal_title：Journal of neurophysiology

authors： Franks CJ,Pemberton D,Vinogradova I,Cook A,Walker RJ,Holden-Dye L

更新日期：2002-02-01 00:00:00

abstract：:Two identified locust neurons, the lobula giant movement detector (LGMD) and its postsynaptic partner, the descending contralateral movement detector (DCMD), constitute one motion-sensitive pathway in the visual system that responds preferentially to objects that approach on a direct collision course and are implicate...

journal_title：Journal of neurophysiology

authors： McMillan GA,Gray JR

更新日期：2012-08-01 00:00:00

abstract：:The extracellular pH of living tissue in the retina and elsewhere in the brain is lower than the pH of the surrounding milieu. We have shown that the pH gradient between the in vitro retina and the superfusion solution is regulated by a circadian (24-h) clock so that it is smaller in the subjective day than in the sub...

journal_title：Journal of neurophysiology

authors： Dmitriev AV,Mangel SC

更新日期：2004-06-01 00:00:00

abstract：:We examined the characteristics of heterosynaptic long-term depression (LTD) and depotentiation of previously established long-term potentiation (LTP) in the medial and lateral entorhinal afferents to the dentate gyrus in the awake rat. Rats were prepared for chronic recording of dentate gyrus evoked potentials to act...

journal_title：Journal of neurophysiology

authors： Doyère V,Srebro B,Laroche S

更新日期：1997-02-01 00:00:00

abstract：:Detection and discrimination of odors generally, if not always, occurs against an odorous background. On any given inhalation, olfactory receptor neurons will be activated by features of both the target odorant and features of background stimuli. To identify a target odorant against a background therefore, the olfacto...

journal_title：Journal of neurophysiology

authors： Kadohisa M,Wilson DA

更新日期：2006-03-01 00:00:00

abstract：:The presence of a calcium-activated nonspecific cationic (CAN) current in turtle motoneurons and its involvement in plateau potentials, bistability, and wind-up was investigated by intracellular recordings in a spinal cord slice preparation. In the presence of tetraethylammonium (TEA) and tetrodotoxin (TTX), calcium a...

journal_title：Journal of neurophysiology

authors： Perrier JF,Hounsgaard J

更新日期：1999-08-01 00:00:00

abstract：:Sexually dimorphic behaviors develop under the influence of sex steroids, which induce reversible changes in the underlying neural network of the brain. However, little is known about the proteins that mediate these activational effects of sex steroids. Here, we used a proteomics approach for large-scale identificatio...

journal_title：Journal of neurophysiology

authors： Zupanc GK,Ilies I,Sîrbulescu RF,Zupanc MM

更新日期：2014-04-01 00:00:00

abstract：:The distribution of functional neurotransmitter receptors is an important determinant of neuronal information processing. To map the location of functional glutamate and GABA receptors on individual hippocampal neurons, we photolyzed "caged" glutamate and GABA while measuring the electrical currents resulting from act...

journal_title：Journal of neurophysiology

authors： Pettit DL,Augustine GJ

更新日期：2000-07-01 00:00:00

abstract：:The abundance of nitric oxide (NO) synthesizing enzymes identified in the vertebrate retina highlight the importance of NO as a signaling molecule in this tissue. Here we describe opposing actions of NO on the rod and cone photoreceptor synapse. Depolarization-induced increases of calcium concentration in rods and con...

journal_title：Journal of neurophysiology

authors： Kourennyi DE,Liu XD,Hart J,Mahmud F,Baldridge WH,Barnes S

更新日期：2004-07-01 00:00:00

abstract：:The topographical response of a portion of an isofrequency contour in primary cat auditory cortex (AI) to a series of monaural and binaural stimuli was studied. Responses of single neurons to monaural and a matrix of binaural characteristic frequency tones, varying in average binaural level (ABL) and interaural level ...

journal_title：Journal of neurophysiology

authors： Nakamoto KT,Zhang J,Kitzes LM

更新日期：2004-01-01 00:00:00

abstract：:Complex patterns of intercellular calcium signaling occur in the CA1 and CA2 regions of hippocampal slice organotypic cultures from neonatal mice. Spontaneous localized intercellular Ca2+ waves involving 5-15 cells propagate concentrically from multiple foci in the stratum oriens and s. radiatum. In these same regions...

journal_title：Journal of neurophysiology

authors： Harris-White ME,Zanotti SA,Frautschy SA,Charles AC

更新日期：1998-02-01 00:00:00

abstract：:Properties of calcium spikes revealed during GABAA receptor antagonism in hippocampal CA1 neurons from guinea pigs. J. Neurophysiol. 78: 2269-2279, 1997. Intracellular electrical responses and changes in intracellular calcium concentration ([Ca2+]i) in response to activation of synaptic inputs and to DC injections wer...

journal_title：Journal of neurophysiology

authors： Miura M,Yoshioka M,Miyakawa H,Kato H,Ito KI

更新日期：1997-11-01 00:00:00

abstract：:A tool or probe often functions as an extension of the hand, transmitting vibrations to the hand to produce a percept of the object contacting the tool or probe. This paper reports the psychophysical results of a combined psychophysical and neurophysiological study of the perception of vibration transmitted through a ...

journal_title：Journal of neurophysiology

authors： Brisben AJ,Hsiao SS,Johnson KO

更新日期：1999-04-01 00:00:00

abstract：:Monitoring representative fractions of neurons from multiple brain circuits in behaving animals is necessary for understanding neuronal computation. Here, we describe a system that allows high-channel-count recordings from a small volume of neuronal tissue using a lightweight signal multiplexing headstage that permits...

journal_title：Journal of neurophysiology

authors： Berényi A,Somogyvári Z,Nagy AJ,Roux L,Long JD,Fujisawa S,Stark E,Leonardo A,Harris TD,Buzsáki G

更新日期：2014-03-01 00:00:00

abstract：:1. The effects of dorsal raphe (DR) stimulation on neural activity in the rat lateral hypothalamic area (LHA), including specific glucose-sensitive neurons, were investigated by extracellular and intracellular recording in vivo, and the neurotransmitters involved were determined. 2. In 67 adult male anesthetized rats,...

journal_title：Journal of neurophysiology

authors： Kai Y,Oomura Y,Shimizu N

更新日期：1988-08-01 00:00:00

abstract：:1. During alertness, lemniscal thalamocortical neurons in the ventral medial geniculate body (MGBv) encode sound signals by firing action potentials in a tonic mode. When they are in a burst firing mode, characteristic of thalamic neurons during some sleep states, the same stimuli may have an alerting function, leadin...

journal_title：Journal of neurophysiology

authors： Tennigkeit F,Schwarz DW,Puil E

更新日期：1996-12-01 00:00:00

abstract：:1. The spatial and temporal response characteristics of direction-selective neurons in the nucleus of the optic tract and dorsal terminal nucleus of the accessory optic system (NOT-DTN) of the wallaby were established using moving sinusoidal gratings. This is the first comprehensive investigation of the spatiotemporal...

journal_title：Journal of neurophysiology

authors： Ibbotson MR,Mark RF,Maddess TL

更新日期：1994-12-01 00:00:00

abstract：:To understand the role of primary visual cortex (V1) in color vision, we measured directly the input from the 3 cone types in macaque V1 neurons. Cells were classified as luminance-preferring, color-luminance, or color-preferring from the ratio of the peak amplitudes of spatial frequency responses to red/green equilum...

journal_title：Journal of neurophysiology

authors： Johnson EN,Hawken MJ,Shapley R

更新日期：2004-06-01 00:00:00

abstract：:The amino acid sequence of the N-methyl-D-aspartate (NMDA) receptor subunit NR2B from the brown ghost knife fish Apteronotus leptorhynchus has been determined and compared with the sequence of the murine NR2B. This comparison revealed high levels of sequence conservation throughout the ligand binding and membrane span...

journal_title：Journal of neurophysiology

authors： Harvey-Girard E,Dunn RJ

更新日期：2003-02-01 00:00:00

abstract：:It has recently become clear that microglia, the immune cells of the central nervous system, are far more active in the healthy brain than previously thought. Microglia facilitate many stages of brain development by shaping neuronal connectivity via synaptic elimination. Dysfunction of these same processes likely unde...

journal_title：Journal of neurophysiology

authors： Whitelaw BS

更新日期：2018-01-01 00:00:00

abstract：:The discovery that spontaneous fluctuations in blood oxygen level-dependent (BOLD) signals contain information about the functional organization of the brain has caused a paradigm shift in neuroimaging. It is now well established that intrinsic brain activity is organized into spatially segregated resting-state networ...

journal_title：Journal of neurophysiology

authors： Mitra A,Snyder AZ,Hacker CD,Raichle ME

更新日期：2014-06-01 00:00:00

abstract：:1. The modulation of reflex responses in up to 10 simultaneously recorded hindlimb muscles was studied in unrestrained cats walking on a treadmill. Single electrical shocks of various strengths were applied to different skin areas of teh hindlimb at different times of the step cycle while the resulting EMG responses w...

journal_title：Journal of neurophysiology

authors： Duysens J,Loeb GE

更新日期：1980-11-01 00:00:00

abstract：:Motor cortex (M1) activity between postnatal weeks 5 and 7 is essential for normal development of the corticospinal tract (CST) and visually guided movements. Unilateral reversible inactivation of M1, by intracortical muscimol infusion, during this period permanently impairs development of the normal dorsoventral dist...

journal_title：Journal of neurophysiology

authors： Chakrabarty S,Friel KM,Martin JH

更新日期：2009-03-01 00:00:00

abstract：:Midcervical spinal interneurons form a complex and diffuse network and may be involved in modulating phrenic motor output. The intent of the current work was to enable a better understanding of midcervical "network-level" connectivity by pairing the neurophysiological multielectrode array (MEA) data with histological ...

journal_title：Journal of neurophysiology

authors： Streeter KA,Sunshine MD,Patel SR,Liddell SS,Denholtz LE,Reier PJ,Fuller DD,Baekey DM

更新日期：2017-03-01 00:00:00

abstract：:Event-related potentials (ERPs) have provided crucial data concerning the time course of psychological processes, but the neural mechanisms producing ERP components remain poorly understood. This study continues a program of research in which we investigated the neural basis of attention-related ERP components by simu...

journal_title：Journal of neurophysiology

authors： Purcell BA,Schall JD,Woodman GF

更新日期：2013-01-01 00:00:00

abstract：:There is evidence that postural instability associated with Parkinson's disease (PD) is not adequately improved by levodopa, implying involvement of nondopaminergic pathways. However, the mechanisms contributing to postural instability have yet to be fully identified and tested for their levodopa responsiveness. In th...

journal_title：Journal of neurophysiology

authors： Di Giulio I,St George RJ,Kalliolia E,Peters AL,Limousin P,Day BL

更新日期：2016-08-01 00:00:00