Large-scale identification of proteins involved in the development of a sexually dimorphic behavior.

abstract：:Proteinase-activated receptors (PARs) have a unique activation mechanism in that a proteolytically exposed N-terminal region acts as a tethered ligand. A potential impact of PAR on sensory processing has not been fully examined yet. Here we report that synthetic peptides with sequences corresponding to PAR ligands enh...

journal_title：Journal of neurophysiology

authors： Fujita T,Liu T,Nakatsuka T,Kumamoto E

更新日期：2009-07-01 00:00:00

abstract：:The concept of hierarchical motor control has been viewed as a means of progressively decreasing the number of variables manipulated by each higher control level. We tested the hypothesis that turning an individual bimanual force-production task into a joint (two-participant) force-production task would lead to positi...

journal_title：Journal of neurophysiology

authors： Masumoto J,Inui N

更新日期：2015-06-01 00:00:00

abstract：:Dopaminergic modulation produces a variety of functional changes in the principal cell of the striatum, the medium spiny neuron (MSN). Using a 189-compartment computational model of a ventral striatal MSN, we simulated whole cell D1- and D2-receptor-mediated modulation of both intrinsic (sodium, calcium, and potassium...

journal_title：Journal of neurophysiology

authors： Moyer JT,Wolf JA,Finkel LH

更新日期：2007-12-01 00:00:00

abstract：:In this study we attempted to identify the principles that govern the changes in neural control that occur during repeated performance of a multiarticular coordination task. Eight participants produced isometric flexion/extension and pronation/supination torques at the radiohumeral joint, either in isolation (e.g., fl...

journal_title：Journal of neurophysiology

authors： Shemmell J,Forner M,Tresilian JR,Riek S,Barry BK,Carson RG

更新日期：2005-11-01 00:00:00

abstract：:The rostral ventromedial medulla (RVM) modulates nociception through changes in the activity of two classes of neuron, ON- and OFF-cells. The activity of these neurons is regulated, in part, by input from the periaqueductal gray (PAG). The objective of this study was to determine whether PAG-mediated antinociception i...

journal_title：Journal of neurophysiology

authors： Tortorici V,Morgan MM

更新日期：2002-10-01 00:00:00

abstract：:The performance of neural codes to represent attributes of sensory signals has been evaluated in the vertebrate peripheral and central nervous system. Here, we determine how information signaled by populations of neurons is modified by plasticity. Suprathreshold neuronal responses from a large number of neurons were r...

journal_title：Journal of neurophysiology

authors： Pita-Almenar JD,Ranganathan GN,Koester HJ

更新日期：2011-09-01 00:00:00

abstract：:1. The purpose of this study is to analyze the kinematics of stepping from the point of view of limb control by attempting to dissociate the various neuronal and mechanical factors that shape actual movements observed experimentally. The cat hindlimb, like the primate arm, is a multijointed mechanical system with redu...

journal_title：Journal of neurophysiology

authors： Shen L,Poppele RE

更新日期：1995-12-01 00:00:00

abstract：:GABAergic interneurons in the hippocampus express high levels of alpha7 nicotinic acetylcholine receptors, but because of the diverse roles played by hippocampal interneurons, the impact of activation of these receptors on hippocampal output neurons (i.e., CA1 pyramidal cells) is unclear. Activation of hippocampal int...

journal_title：Journal of neurophysiology

authors： Buhler AV,Dunwiddie TV

更新日期：2002-01-01 00:00:00

abstract：:Stimulus-specific adaptation is the phenomenon whereby neural response magnitude decreases with repeated stimulation. Inconsistencies between recent nonhuman animal recordings and computational modeling suggest dynamic influences on stimulus-specific adaptation. The present human electroencephalography (EEG) study inv...

journal_title：Journal of neurophysiology

authors： Herrmann B,Henry MJ,Fromboluti EK,McAuley JD,Obleser J

更新日期：2015-04-01 00:00:00

abstract：:Activity-dependent developmental maturation of the neocortical network is thought to involve the stabilization and potentiation of immature synapses. In particular, N-methyl-d-aspartate (NMDA) receptor-dependent long-term plasticity that is expressed presynaptically appears to be crucial for the selection of functiona...

journal_title：Journal of neurophysiology

authors： Walz C,Jüngling K,Lessmann V,Gottmann K

更新日期：2006-12-01 00:00:00

abstract：:1. We have stimulated responses of stellate cells in the anteroventral cochlear nucleus (AVCN) to single-formant stimuli (SFSs) with the use of recorded auditory-nerve fiber (ANF) responses as inputs. In particular, two important features of temporal discharge patterns, the phase locking to best frequency (BF) tones a...

journal_title：Journal of neurophysiology

authors： Wang X,Sachs MB

更新日期：1995-04-01 00:00:00

abstract：:1. The horizontal eye movements induced by acceleration along the interaural axis were recorded from five monkeys (Macaca mulatta) by the use of the electromagnetic search-coil technique. Animals sat on a sled that was moved briefly in darkness along a linear track (bell-shaped acceleration profile: peak, 400 mm/s2; d...

journal_title：Journal of neurophysiology

authors： Schwarz U,Miles FA

更新日期：1991-09-01 00:00:00

abstract：:The problem of how the hippocampus encodes both spatial and nonspatial information at the cellular network level remains largely unresolved. Spatial memory is widely modeled through the theoretical framework of attractor networks, but standard computational models can only represent spaces that are much smaller than t...

journal_title：Journal of neurophysiology

authors： Hedrick KR,Zhang K

更新日期：2016-08-01 00:00:00

abstract：:We perceive objects as permanent and stable despite frequent occlusions and eye movements, but their representation in the visual cortex is neither permanent nor stable. Feature selective cells respond only as long as objects are visible, and their responses depend on eye position. We explored the hypothesis that the ...

journal_title：Journal of neurophysiology

authors： Zhu SD,Zhang LA,von der Heydt R

更新日期：2020-05-01 00:00:00

abstract：:The lability of the responses of mammalian central neurons to gamma-aminobutyric acid (GABA) was studied using neurons acutely dissociated from the CA1 region of the adult guinea pig hippocampus as a model system. GABA was applied to the neuronal somata by pressure ejection and the resulting current (IGABA) recorded u...

journal_title：Journal of neurophysiology

authors： Huguenard JR,Alger BE

更新日期：1986-07-01 00:00:00

abstract：:Basal ganglia circuits are organized as parallel loops that have been proposed to compete in a winner-take-all fashion to determine the appropriate behavioral outcome. However, limited experimental support for strong lateral inhibition mechanisms within striatal regions questions this model. Here, stimulation of the p...

journal_title：Journal of neurophysiology

authors： Gruber AJ,Powell EM,O'Donnell P

更新日期：2009-04-01 00:00:00

abstract：:The auditory frequency-following response (FFR) reflects synchronized and phase-locked activity along the auditory pathway in response to sound. Although FFRs were historically thought to reflect subcortical activity, recent evidence suggests an auditory cortex contribution as well. Here we present electrophysiologica...

journal_title：Journal of neurophysiology

authors： White-Schwoch T,Anderson S,Krizman J,Nicol T,Kraus N

更新日期：2019-08-01 00:00:00

abstract：:A brain slice preparation from guinea pigs and intracellular recording techniques were used to examine the effects of carbachol application on the three classes (A, B, and C) of neurons (n = 68, 40 of class A, 12 of class B, 16 of class C) within the mediolateral part of the lateral septum (LSml). Bath application of ...

journal_title：Journal of neurophysiology

authors： Carette B

更新日期：1998-09-01 00:00:00

abstract：:The computational role of the olfactory bulb remains a mystery after 60 yr of physiological research. Recently, Fantana and colleagues proposed a new model of bulb function based on sparse inhibitory connections between glomeruli, the functional units of the bulb, rather than the existing lateral inhibition model. I p...

journal_title：Journal of neurophysiology

authors： Ghatpande AS

更新日期：2009-01-01 00:00:00

abstract：:1. Movement of the crayfish thoracocoxal leg joint is monitored by a muscle receptor organ (TCMRO) and a chordotonal organ (TCCO). Both receptors span the joint in parallel but signal opposite directions of leg movement. The TCMRO is innervated by afferents responsive to lengthening, which corresponds to leg remotion,...

journal_title：Journal of neurophysiology

authors： Skorupski P,Rawat BM,Bush BM

更新日期：1992-03-01 00:00:00

abstract：:Retinotopy is a fundamental organizing principle of the visual cortex. Over the years, a variety of techniques have been used to examine it. None of these techniques, however, provides a way to rapidly characterize retinotopy, at the submillimeter range, in alert, behaving subjects. Voltage-sensitive dye imaging (VSDI...

journal_title：Journal of neurophysiology

authors： Yang Z,Heeger DJ,Seidemann E

更新日期：2007-08-01 00:00:00

abstract：:The majority of cerebral signals destined for the cerebellum are handed over by the pontine nuclei (PN), which thoroughly reorganize the neocortical topography. The PN maps neocortical signals of wide-spread origins into adjacent compartments delineated by spatially precise distribution of cortical terminals and posts...

journal_title：Journal of neurophysiology

authors： Möck M,Butovas S,Schwarz C

更新日期：2006-06-01 00:00:00

abstract：:Electrophysiological recordings show intense neuronal firing during epileptic seizures leading to enhanced energy consumption. However, the relationship between oxygen metabolism and seizure patterns has not been well studied. Recent studies have developed fast and quantitative techniques to measure oxygen microdomain...

journal_title：Journal of neurophysiology

authors： Wei Y,Ullah G,Ingram J,Schiff SJ

更新日期：2014-07-15 00:00:00

abstract：:1. Whole-cell patch-clamp recordings of excitatory postsynaptic currents (EPSCs) were made from guinea pig hippocampal CA1 pyramidal cells. The sensitivity of paired pulse facilitation (PPF) and EPSC variance to changes in synaptic transmission was investigated and the results were compared with the changes in these p...

journal_title：Journal of neurophysiology

authors： Manabe T,Wyllie DJ,Perkel DJ,Nicoll RA

更新日期：1993-10-01 00:00:00

abstract：:1. Previous studies indicate that after transection of the rostral spinal cord, larval lamprey begin to recover locomotor behavior 2 wk posttransection and recovery is complete at approximately 8 wk. To examine the mechanisms underlying behavioral recovery after spinal cord transection, in the present study the time c...

journal_title：Journal of neurophysiology

authors： McClellan AD

更新日期：1994-08-01 00:00:00

abstract：:The ventromedial medulla is implicated in a variety of functions including nociceptive and cardiovascular modulation and the control of thermoregulation. To determine whether single microinjections into the ventromedial medulla elicit changes in one or multiple functional systems, the GABA(A) receptor antagonist bicuc...

journal_title：Journal of neurophysiology

authors： Nason MW Jr,Mason P

更新日期：2004-07-01 00:00:00

abstract：:The potassium-chloride cotransporter 2 (KCC2) plays a role in epileptiform synchronization, but it remains unclear how it influences such a process. Here, we used tetrode recordings in the in vitro rat entorhinal cortex (EC) to analyze the effects of the KCC2 antagonist VU0463271 on 4-aminopyridine (4AP)-induced ictal...

journal_title：Journal of neurophysiology

authors： Chen LY,Lévesque M,Avoli M

更新日期：2019-09-01 00:00:00

abstract：:Dual whole-cell patch clamp recordings from the soma and dendrites of CA1 pyramidal neurons located in hippocampal slices of adult rats were used to examine the potential mechanisms of phase precession. To mimic phasic synaptic input, 5-Hz sine wave current injections were simultaneously delivered both to the soma and...

journal_title：Journal of neurophysiology

authors： Magee JC

更新日期：2001-07-01 00:00:00

abstract：:The corticospinal tract excitability is modulated when preparing movements. Earlier to movement execution, the excitability of the spinal cord increases waiting for supraspinal commands to release the movement. Movement execution and movement observation share processes within the motor system, although movement obser...

journal_title：Journal of neurophysiology

authors： Arias P,Robles-García V,Espinosa N,Corral-Bergantiños Y,Mordillo-Mateos L,Grieve K,Oliviero A,Cudeiro J

更新日期：2014-04-01 00:00:00

abstract：:Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are responsible for the functional hyperpolarization-activated current (I(h)) in dorsal root ganglion (DRG) neurons, playing an important role in pain processing. We found that the known analgesic loperamide inhibited I(h) channels in rat DRG neurons. ...

journal_title：Journal of neurophysiology

authors： Vasilyev DV,Shan Q,Lee Y,Mayer SC,Bowlby MR,Strassle BW,Kaftan EJ,Rogers KE,Dunlop J

更新日期：2007-05-01 00:00:00