Motor control hierarchy in joint action that involves bimanual force production.

abstract：:1. The effects of gamma-aminobutyric acid (GABA) on non-GABAA receptors were investigated with intracellular recordings in CA1 pyramidal cells of rat hippocampal slices in the presence of antagonists of GABAA receptors (50 microM bicuculline and 50 microM picrotoxin), N-methyl-D-aspartate (NMDA) and non-NMDA receptors...

journal_title：Journal of neurophysiology

authors： Pham TM,Lacaille JC

更新日期：1996-07-01 00:00:00

abstract：:The functional and biophysical properties of a persistent sodium current (I(NaP)) previously proposed to participate in the generation of subthreshold oscillations and burst discharge in mesencephalic trigeminal sensory neurons (Mes V) were investigated in brain stem slices (rats, p7-p12) using whole cell patch-clamp ...

journal_title：Journal of neurophysiology

authors： Wu N,Enomoto A,Tanaka S,Hsiao CF,Nykamp DQ,Izhikevich E,Chandler SH

更新日期：2005-05-01 00:00:00

abstract：:Synapsin is a synaptic vesicle-associated protein implicated in the regulation of vesicle trafficking and transmitter release, but its role in heterosynaptic plasticity remains elusive. Moreover, contradictory results have obscured the contribution of synapsin to homosynaptic plasticity. We previously reported that th...

journal_title：Journal of neurophysiology

authors： Fioravante D,Liu RY,Netek AK,Cleary LJ,Byrne JH

更新日期：2007-12-01 00:00:00

abstract：:When speed changes during locomotion, both temporal and spatial parameters of the pattern must adjust. Moreover, at slow speeds the step-to-step pattern becomes increasingly variable. The objectives of the present study were to assess if the spinal locomotor network adjusts both temporal and spatial parameters from sl...

journal_title：Journal of neurophysiology

authors： Dambreville C,Labarre A,Thibaudier Y,Hurteau MF,Frigon A

更新日期：2015-08-01 00:00:00

abstract：:Support-surface movements are commonly used to examine balance control. Subjects typically receive a series of identical or randomly interspersed multidirectional balance perturbations and the atypical "first trial reaction" (evoked by the first perturbation) is often excluded from further analysis. However, this proc...

journal_title：Journal of neurophysiology

authors： Oude Nijhuis LB,Allum JH,Borm GF,Honegger F,Overeem S,Bloem BR

更新日期：2009-06-01 00:00:00

abstract：:In the first visual synapse of the insect compound eye, both the presynaptic and postsynaptic signals are graded, nonspiking changes in membrane voltage. The synapse exhibits tonic transmitter release (even in dark) and strong adaptation to long-lasting light backgrounds, leading to changes also in the dynamics of sig...

journal_title：Journal of neurophysiology

authors： Uusitalo RO,Weckström M

更新日期：2000-04-01 00:00:00

abstract：:When the head is free to move, electrical stimulation in the frontal eye field (FEF) evokes eye and head movements. However, it is unclear whether FEF stimulation-evoked head movements contribute to shifting the line of sight, like visually guided coordinated eye-head gaze shifts. Here we investigated this issue by sy...

journal_title：Journal of neurophysiology

authors： Chen LL

更新日期：2006-06-01 00:00:00

abstract：:1. Evidence from single-unit recordings suggests that neurons in the medial superior temporal visual area (MST) carry directional signals that influence psychophysical judgements of motion direction. We tested this hypothesis by electrically stimulating clusters of directionally selective neurons in MST (the dorsomedi...

journal_title：Journal of neurophysiology

authors： Celebrini S,Newsome WT

更新日期：1995-02-01 00:00:00

abstract：:Despite the importance of the thumb to hand function, little is known about the origins of thumb impairment poststroke. Accordingly, the primary purpose of this study was to assess whether thumb flexors have heightened stretch reflexes (SRs) following stroke-induced hand impairment. The secondary purpose was to compar...

journal_title：Journal of neurophysiology

authors： Towles JD,Kamper DG,Rymer WZ

更新日期：2010-10-01 00:00:00

abstract：:Nonsynaptic mechanisms exert a powerful influence on seizure threshold. It is well-established that nonsynaptic epileptiform activity can be induced in hippocampal slices by reducing extracellular Ca(2+) concentration. We show here that nonsynaptic epileptiform activity can be readily induced in vitro in normal (2 mM)...

journal_title：Journal of neurophysiology

authors： Bikson M,Baraban SC,Durand DM

更新日期：2002-01-01 00:00:00

abstract：:Regeneration of a cut muscle nerve fails to restore the stretch reflex, and the companion paper to this article [Alvarez FJ, Titus-Mitchell HE, Bullinger KL, Kraszpulski M, Nardelli P, Cope TC. J Neurophysiol (August 10, 2011). doi:10.1152/jn.01095.2010] suggests an important central contribution from substantial and ...

journal_title：Journal of neurophysiology

authors： Bullinger KL,Nardelli P,Pinter MJ,Alvarez FJ,Cope TC

更新日期：2011-11-01 00:00:00

abstract：:The present paper investigates the sensory-driven modulations of central pattern generator dynamics that can be expected to reproduce human behavior during rhythmic hybrid tasks. We propose a theoretical model of human sensorimotor behavior able to account for the observed data from the ball-bouncing task. The novel c...

journal_title：Journal of neurophysiology

authors： Avrin G,Siegler IA,Makarov M,Rodriguez-Ayerbe P

更新日期：2017-10-01 00:00:00

abstract：:Following the groundbreaking discovery of grid cells, the medial entorhinal cortex (MEC) has become the focus of intense anatomical, physiological, and computational investigations. Whether and how grid activity maps onto cell types and cortical architecture is still an open question. Fundamental similarities in micro...

journal_title：Journal of neurophysiology

authors： Naumann RK,Preston-Ferrer P,Brecht M,Burgalossi A

更新日期：2018-06-01 00:00:00

abstract：:AMPA-type glutamate receptors are normally Ca(2+) impermeable due to the expression of the GluR2 receptor subunit. By using GluR2 null mice we were able to detect miniature synaptic Ca(2+) transients (MSCTs) associated with AMPA-type receptor-mediated miniature synaptic currents at single synapses in primary cortical ...

journal_title：Journal of neurophysiology

authors： Wang S,Jia Z,Roder J,Murphy TH

更新日期：2002-07-01 00:00:00

abstract：:Coherence analysis has the ability to identify the presence of common descending drive shared by motor unit pools and reveals its spectral properties. However, the link between spectral properties of shared neural drive and functional interactions among muscles remains unclear. We assessed shared neural drive between ...

journal_title：Journal of neurophysiology

authors： Laine CM,Valero-Cuevas FJ

更新日期：2017-09-01 00:00:00

abstract：:Children with secondary dystonia due to cerebral palsy exhibit abnormal upper extremity postures and slow voluntary movement. However, the interaction between abnormal postures and abnormal movement in dystonia is still unclear. Some mechanisms by which postures are maintained in dystonia include stretch reflexes, ove...

journal_title：Journal of neurophysiology

authors： Kukke SN,Sanger TD

更新日期：2011-05-01 00:00:00

abstract：:A plaid pattern is formed when two sinusoidal gratings of different orientations are added together. Previous work has shown that V1 neurons selectively encode the direction and orientation of the component gratings in a moving plaid but not the direction of the plaid itself (Movshon et al. 1985). We recorded the resp...

journal_title：Journal of neurophysiology

authors： Tinsley CJ,Webb BS,Barraclough NE,Vincent CJ,Parker A,Derrington AM

更新日期：2003-08-01 00:00:00

abstract：:In this study, we examined the effect of arachidonic acid (AA) on the BK alpha-subunit with or without beta-subunits expressed in Xenopus oocytes. In excised patches, AA potentiated the hSlo-alpha current and slowed inactivation only when beta2/3 subunit was co-expressed. The beta2-subunit-dependent modulation by AA p...

journal_title：Journal of neurophysiology

authors： Sun X,Zhou D,Zhang P,Moczydlowski EG,Haddad GG

更新日期：2007-01-01 00:00:00

abstract：:The relationship among neonatal seizures, abnormalities of the electroencephalogram (EEG), brain injury, and long-term neurological outcome (e.g., epilepsy) remains controversial. The effects of hypoxia alone (Ha) and hypoxia-ischemia (HI) were studied in neonatal rats at postnatal day 7; both models generate EEG seiz...

journal_title：Journal of neurophysiology

authors： Zayachkivsky A,Lehmkuhle MJ,Ekstrand JJ,Dudek FE

更新日期：2015-11-01 00:00:00

abstract：:The recurrent mossy fiber pathway of the dentate gyrus expands dramatically in many persons with temporal lobe epilepsy. The new connections among granule cells provide a novel mechanism of synchronization that could enhance the participation of these cells in seizures. Despite the presence of robust recurrent mossy f...

journal_title：Journal of neurophysiology

authors： Hardison JL,Okazaki MM,Nadler JV

更新日期：2000-11-01 00:00:00

abstract：:Previous studies have described maturational changes in GABAergic inhibitory synaptic transmission in the rodent somatosensory cortex during the early postnatal period. To determine whether alterations in the functional properties of synaptically localized GABA(A) receptors (GABA(A)Rs) contribute to development of inh...

journal_title：Journal of neurophysiology

authors： Dunning DD,Hoover CL,Soltesz I,Smith MA,O'Dowd DK

更新日期：1999-12-01 00:00:00

abstract：:Electrophysiological recordings show intense neuronal firing during epileptic seizures leading to enhanced energy consumption. However, the relationship between oxygen metabolism and seizure patterns has not been well studied. Recent studies have developed fast and quantitative techniques to measure oxygen microdomain...

journal_title：Journal of neurophysiology

authors： Wei Y,Ullah G,Ingram J,Schiff SJ

更新日期：2014-07-15 00:00:00

abstract：:A brain slice preparation from guinea pigs and intracellular recording techniques were used to examine the effects of carbachol application on the three classes (A, B, and C) of neurons (n = 68, 40 of class A, 12 of class B, 16 of class C) within the mediolateral part of the lateral septum (LSml). Bath application of ...

journal_title：Journal of neurophysiology

authors： Carette B

更新日期：1998-09-01 00:00:00

abstract：:Long-term depression (LTD) of synaptic transmission can be induced by several mechanisms, one thought to involve Ca2+-dependent activation of postsynaptic nitric oxide (NO) synthase and subsequent diffusion of NO to the presynaptic terminal. We used the stable NO donor S-nitroso-N-acetylpenicillamine (SNAP) to study t...

journal_title：Journal of neurophysiology

authors： Reyes-Harde M,Potter BV,Galione A,Stanton PK

更新日期：1999-09-01 00:00:00

abstract：:The hypocretin/orexins (Hcrt/Orxs) are hypothalamic neuropeptides that regulate stress, addiction, feeding, and arousal behaviors. They depolarize many types of central neurons and can increase [Ca2+]i in some, including those of the dorsal raphe (DR) and laterodorsal tegmental (LDT) nuclei-two structures likely to co...

journal_title：Journal of neurophysiology

authors： Kohlmeier KA,Watanabe S,Tyler CJ,Burlet S,Leonard CS

更新日期：2008-10-01 00:00:00

abstract：:One of the hallmarks of cognitive control is the suppression of prepotent but inappropriate responses. Here we used event-related functional MRI to measure functional brain activation during a stimulus-response incompatibility task. Subjects were instructed before a stimulus appeared either to look at the stimulus (pr...

journal_title：Journal of neurophysiology

authors： Ford KA,Goltz HC,Brown MR,Everling S

更新日期：2005-07-01 00:00:00

abstract：:We have studied how rewards modulate the occurrence of microsaccades by manipulating the size of an expected reward and the location of the cue that sets the expectations for future reward. We found an interaction between the size of the reward and the location of the cue. When monkeys fixated on a cue that signaled t...

journal_title：Journal of neurophysiology

authors： Joshua M,Tokiyama S,Lisberger SG

更新日期：2015-11-01 00:00:00

abstract：:Response adaptation is the change of the firing rate of neurons induced by a preceding stimulus. It can be found in many sensory systems and throughout the auditory pathway. We investigated response adaptation in the external nucleus of the inferior colliculus (ICX) of barn owls ( Tyto furcata), a nocturnal bird of pr...

journal_title：Journal of neurophysiology

authors： Ferger R,Pawlowsky K,Singheiser M,Wagner H

更新日期：2018-03-01 00:00:00

abstract：:The widespread noradrenergic innervation in the brain promotes arousal and learning by molecular mechanisms that remain largely undefined. Recent work shows that the β(2)-adrenergic receptor (β(2)AR) is linked to the AMPA-type glutamate receptor subunit GluA1 via stargazin and PSD-95 (Joiner ML, Lise MF, Yuen EY, Kam ...

journal_title：Journal of neurophysiology

authors： Qian H,Matt L,Zhang M,Nguyen M,Patriarchi T,Koval OM,Anderson ME,He K,Lee HK,Hell JW

更新日期：2012-05-01 00:00:00

abstract：:Mechanoelectric transducer (MET) channels, located near stereocilia tips, are opened by deflecting the hair bundle of sensory hair cells. Defects in this process result in deafness. Despite this critical function, the molecular identity of MET channels remains a mystery. Inherent channel properties, particularly those...

journal_title：Journal of neurophysiology

authors： Pan B,Waguespack J,Schnee ME,LeBlanc C,Ricci AJ

更新日期：2012-05-01 00:00:00