Conditions sufficient for nonsynaptic epileptogenesis in the CA1 region of hippocampal slices.

abstract：:Brain-derived neurotrophic factor (BDNF) can potentiate synaptic release at newly developed frog neuromuscular junctions. Although this potentiation depends on extracellular Ca(2+) and reflects changes in acetylcholine release, little is known about the intracellular transduction or calcium signaling pathways. We have...

journal_title：Journal of neurophysiology

authors： Kleiman RJ,Tian N,Krizaj D,Hwang TN,Copenhagen DR,Reichardt LF

更新日期：2000-07-01 00:00:00

abstract：:Cross-orientation suppression was measured in human primary visual cortex (V1) to test the normalization model. Subjects viewed vertical target gratings (of varying contrasts) with or without a superimposed horizontal mask grating (fixed contrast). We used functional magnetic resonance imaging (fMRI) to measure the ac...

journal_title：Journal of neurophysiology

authors： Brouwer GJ,Heeger DJ

更新日期：2011-11-01 00:00:00

abstract：:Itch is often triggered by warming the skin in patients with itchy dermatitis, but the underlying mechanism is largely unknown. We presently investigated if warming the skin enhances histamine- or serotonin (5-HT)-evoked itch behavior or responses of sensory dorsal root ganglion (DRG) cells, and if responses of superf...

journal_title：Journal of neurophysiology

authors： Akiyama T,Nagamine M,Davoodi A,Ivanov M,Carstens MI,Carstens E

更新日期：2017-01-01 00:00:00

abstract：:Trimming all whiskers except two on one side of an adult rat's face results in cortical plasticity in which the spared whiskers, D2 and one D-row surround whisker (either D1 or D3), evoked responses containing more spikes than the response evoked by the cut whisker (called whisker pairing plasticity). Previously we ha...

journal_title：Journal of neurophysiology

authors： Sachdev RN,Egli M,Stonecypher M,Wiley RG,Ebner FF

更新日期：2000-10-01 00:00:00

abstract：:1. Two buccal ganglia interneurons, labeled here as B51 and B52, have been identified on the basis of morphological and physiological criteria. 2. These neurons have multipolar cell bodies. B51 extends a major neurite, which arborizes in the neuropil ipsilateral to the soma; extends into the buccal commissure, where i...

journal_title：Journal of neurophysiology

authors： Plummer MR,Kirk MD

更新日期：1990-03-01 00:00:00

abstract：:In many central pattern generators, pairs of neurons maintain an approximately fixed phase despite large changes in the frequency. The mechanisms underlying phase maintenance are not clear. Previous theoretical work suggested that inhibitory synapses that show short-term depression could play a critical role in this r...

journal_title：Journal of neurophysiology

authors： Greenberg I,Manor Y

更新日期：2005-02-01 00:00:00

abstract：:We introduce a new method to unveil the network connectivity among dozens of neurons in brain slice preparations. While synaptic inputs were whole cell recorded from given postsynaptic neurons, the spatiotemporal firing patterns of presynaptic neuron candidates were monitored en masse with functional multineuron calci...

journal_title：Journal of neurophysiology

authors： Sasaki T,Minamisawa G,Takahashi N,Matsuki N,Ikegaya Y

更新日期：2009-07-01 00:00:00

abstract：:The generation of a behaviorally relevant cue to the speed of objects around us is critical to our ability to navigate safely within our environment. However, our perception of speed is often distorted by prevailing conditions. For instance, as luminance is reduced, our perception of the speed of fast-moving patterns ...

journal_title：Journal of neurophysiology

authors： Hammett ST,Smith AT,Wall MB,Larsson J

更新日期：2013-08-01 00:00:00

abstract：:Small lesions designed to completely destroy the cortical zone of representation of a restricted band of frequency were introduced within the primary auditory cortex (AI) in adult cats. Physiological mapping was used to guide placement of lesions. Sound-localization performance was evaluated prior to and after inducti...

journal_title：Journal of neurophysiology

authors： Jenkins WM,Merzenich MM

更新日期：1984-11-01 00:00:00

abstract：:The functional role of input from the primary motor cortex (M1) to primary somatosensory cortex (S1) is unclear; one key to understanding this pathway may lie in elucidating the cell-type specific microcircuits that connect S1 and M1. Recently, we discovered that a subset of pyramidal neurons in the infragranular laye...

journal_title：Journal of neurophysiology

authors： Kinnischtzke AK,Fanselow EE,Simons DJ

更新日期：2016-09-01 00:00:00

abstract：:The voltage-gated K(+) channel Kv1.3 has been reported to regulate transmitter release in select central and peripheral neurons. In this study, we evaluated its role at the synapse between visceral sensory afferents and secondary neurons in the nucleus of the solitary tract (NTS). We identified mRNA and protein for Kv...

journal_title：Journal of neurophysiology

authors： Ramirez-Navarro A,Glazebrook PA,Kane-Sutton M,Padro C,Kline DD,Kunze DL

更新日期：2011-06-01 00:00:00

abstract：:We used positron emission tomography to study motor learning by trial and error. Subjects learned sequences of eight finger movements. Tones generated by a computer told the subjects whether any particular move was correct or incorrect. A control condition was used in which the subjects generated moves, but there was ...

journal_title：Journal of neurophysiology

authors： Jueptner M,Frith CD,Brooks DJ,Frackowiak RS,Passingham RE

更新日期：1997-03-01 00:00:00

abstract：:Spontaneous and stimulus-evoked excitatory postsynaptic currents (EPSCs) were recorded in calyx nerve terminals from the turtle vestibular lagena to quantify key attributes of quantal transmission at this synapse. On average, EPSC events had a magnitude of ∼ 42 pA, a rise time constant of τ(0) ∼ 229 μs, decayed to bas...

journal_title：Journal of neurophysiology

authors： Highstein SM,Mann MA,Holstein GR,Rabbitt RD

更新日期：2015-06-01 00:00:00

abstract：:Properties of calcium spikes revealed during GABAA receptor antagonism in hippocampal CA1 neurons from guinea pigs. J. Neurophysiol. 78: 2269-2279, 1997. Intracellular electrical responses and changes in intracellular calcium concentration ([Ca2+]i) in response to activation of synaptic inputs and to DC injections wer...

journal_title：Journal of neurophysiology

authors： Miura M,Yoshioka M,Miyakawa H,Kato H,Ito KI

更新日期：1997-11-01 00:00:00

abstract：:An initial overload of intracellular Ca2+ plays a critical role in the delayed death of hippocampal CA1 neurons that die a few days after transient ischemia. Without direct evidence, the prevailing hypothesis has been that Ca2+ overload may recur until cell death. Here, we report the first measurements of intracellula...

journal_title：Journal of neurophysiology

authors： Connor JA,Razani-Boroujerdi S,Greenwood AC,Cormier RJ,Petrozzino JJ,Lin RC

更新日期：1999-01-01 00:00:00

abstract：:To understand the role of primary visual cortex (V1) in color vision, we measured directly the input from the 3 cone types in macaque V1 neurons. Cells were classified as luminance-preferring, color-luminance, or color-preferring from the ratio of the peak amplitudes of spatial frequency responses to red/green equilum...

journal_title：Journal of neurophysiology

authors： Johnson EN,Hawken MJ,Shapley R

更新日期：2004-06-01 00:00:00

abstract：:Arrays of closely spaced quartz-insulated, platinum-tungsten microelectrodes are widely used to obtain acute recordings from chronically prepared subjects. These electrodes have excellent recording characteristics and can be fabricated to a wide variety of tip specifications. Typically, in such experiments, electrodes...

journal_title：Journal of neurophysiology

authors： Swadlow HA,Bereshpolova Y,Bezdudnaya T,Cano M,Stoelzel CR

更新日期：2005-05-01 00:00:00

abstract：:Tetanus toxin reduces monosynaptic inhibitory and excitatory synaptic transmission in mouse spinal cord neurons in culture. Inhibitory transmission is preferentially reduced by the toxin; however, excitatory transmission is also ultimately reduced and blocked by the concentrations of toxin used in these studies. Recor...

journal_title：Journal of neurophysiology

authors： Bergey GK,Bigalke H,Nelson PG

更新日期：1987-01-01 00:00:00

abstract：:Particular types of amacrine cells of the vertebrate retina show oscillatory membrane potentials (OMPs) in response to light stimulation. Historically it has been thought the oscillations arose as a result of circuit properties. In a previous study we found that in some amacrine cells, the ability to oscillate was an ...

journal_title：Journal of neurophysiology

authors： Vigh J,Solessio E,Morgans CW,Lasater EM

更新日期：2003-07-01 00:00:00

abstract：:1. Intracellular recordings were made from layer VI pyramidal cells in in vitro slice preparations of the cat motor cortex (area 4 gamma). Layer VI pyramidal cells were identified morphologically by intracellular injection of biocytin. 2. Of 22 layer VI pyramidal cells examined, single action potentials were followed ...

journal_title：Journal of neurophysiology

authors： Kang Y,Kayano F

更新日期：1994-08-01 00:00:00

abstract：:Intrathecally applied nicotine reduces bradykinin-induced plasma extravasation (BK-induced PE) in the rat knee joint. This depression is mediated by the hypothalamo-pituitary-adrenal (HPA) axis and is enhanced by interruption of impulse traffic in afferents of the abdominal vagus nerve. Like intrathecal nicotine, elec...

journal_title：Journal of neurophysiology

authors： Miao FJ,Jänig W,Green PG,Levine JD

更新日期：1997-09-01 00:00:00

abstract：:Subfornical organ (SFO) neurons exhibit heterogeneity in current expression and spiking behavior, where the two major spiking phenotypes appear as tonic and burst firing. Insight into the mechanisms behind this heterogeneity is critical for understanding how the SFO, a sensory circumventricular organ, integrates and s...

journal_title：Journal of neurophysiology

authors： Medlock L,Shute L,Fry M,Standage D,Ferguson AV

更新日期：2018-11-01 00:00:00

abstract：:Transection of a peripheral nerve results in withdrawal of synapses from motoneurons. Some of the withdrawn synapses are restored spontaneously, but those containing the vesicular glutamate transporter 1 (VGLUT1), and arising mainly from primary afferent neurons, are withdrawn permanently. If animals are exercised imm...

journal_title：Journal of neurophysiology

authors： Brandt J,Evans JT,Mildenhall T,Mulligan A,Konieczny A,Rose SJ,English AW

更新日期：2015-04-01 00:00:00

abstract：:Motor networks such as the pyloric network of the stomatogastric ganglion often require descending neuromodulatory inputs to initiate, regulate, and modulate their activity and their synaptic connectivity to manifest physiologically appropriate output. Prolonged removal of these descending inputs often results in a co...

journal_title：Journal of neurophysiology

authors： Nahar J,Lett KM,Schulz DJ

更新日期：2012-08-01 00:00:00

abstract：:ALS (amyotrophic lateral sclerosis) is an adult-onset and deadly neurodegenerative disease characterized by a progressive and selective loss of motoneurons. Transgenic mice overexpressing a mutated human gene (G93A) coding for the enzyme SOD1 (Cu/Zn superoxide dismutase) develop a motoneuron disease resembling ALS in ...

journal_title：Journal of neurophysiology

authors： Kuo JJ,Schonewille M,Siddique T,Schults AN,Fu R,Bär PR,Anelli R,Heckman CJ,Kroese AB

更新日期：2004-01-01 00:00:00

abstract：:Substance P (SP) is an undecapeptide that is co-localized with conventional transmitters in the nucleus accumbens (NAc). Its neurochemical and behavioral effects resemble those of cocaine and amphetamine. How SP accomplishes these effects is not known, partly because its cellular and synaptic effects are not well char...

journal_title：Journal of neurophysiology

authors： Kombian SB,Ananthalakshmi KV,Parvathy SS,Matowe WC

更新日期：2003-02-01 00:00:00

abstract：:Recent studies have reported that human subjects show varying degrees of ability to use contextual cues to recall the motor skills required to compensate for different dynamic external force fields during arm movements. In particular, the subjects showed little or no ability to use color cues to adjust motor outputs i...

journal_title：Journal of neurophysiology

authors： Krouchev NI,Kalaska JF

更新日期：2003-02-01 00:00:00

abstract：:Saccade adaptation is a mechanism that adjusts saccade landing positions if they systematically fail to reach their intended target. In the laboratory, saccades can be shortened or lengthened if the saccade target is displaced during execution of the saccade. In this study, saccades were performed from different posit...

journal_title：Journal of neurophysiology

authors： Zimmermann E

更新日期：2013-04-01 00:00:00

abstract：:Voluntary and stimulus-driven shifts of attention can modulate the representation of behaviorally relevant stimuli in early areas of visual cortex. In turn, attended items are processed faster and more accurately, facilitating the selection of appropriate behavioral responses. Information processing is also strongly i...

journal_title：Journal of neurophysiology

authors： Serences JT,Saproo S

更新日期：2010-07-01 00:00:00

abstract：:Rodents shift their nose from side to side when they actively explore and lateralize odors in the space. This motor action is driven by a pair of muscles, the deflector nasi. We studied the premotor control of this motion. We used replication-competent rabies virus to transsynaptically label inputs to the deflector na...

journal_title：Journal of neurophysiology

authors： Kurnikova A,Deschênes M,Kleinfeld D

更新日期：2019-01-01 00:00:00