Persistent sodium currents in mesencephalic v neurons participate in burst generation and control of membrane excitability.

abstract：:Previous studies have demonstrated that locally administered cannabinoids attenuate allodynia and hyperalgesia through activation of peripheral cannabinoid receptors (CB(1) and CB(2)). However, it is currently unknown if cannabinoids alter the response properties of nociceptors. In the present study, correlative behav...

journal_title：Journal of neurophysiology

authors： Potenzieri C,Brink TS,Pacharinsak C,Simone DA

更新日期：2008-11-01 00:00:00

abstract：:We previously reported that neurons in the mediodorsal thalamic nucleus (MD) are topographically organized and express spatial and nonspatial coding properties similar to those of the prefrontal areas with which they are connected. In the course of mapping the dorsal thalamus, we also studied neurons in a subset of th...

journal_title：Journal of neurophysiology

authors： Tanibuchi I,Goldman-Rakic PS

更新日期：2005-01-01 00:00:00

abstract：:To characterize spike coding in spinal neurons during rhythmic locomotor activity, we recorded from individual cells in the lumbar spinal cord of neonatal rats by using the on-cell patch-clamp technique. Locomotor activity was induced by N-methyl-D aspartate (NMDA) and 5-hydroxytryptamine (5-HT) and monitored by ventr...

journal_title：Journal of neurophysiology

authors： Raastad M,Kiehn O

更新日期：2000-05-01 00:00:00

abstract：:Our understanding of how we learn and retain motor behaviors is still limited. For instance, there is conflicting evidence as to whether the memory of a learned visuomotor perturbation consolidates; i.e., the motor memory becomes resistant to interference from learning a competing perturbation over time. Here, we soug...

journal_title：Journal of neurophysiology

authors： Maeda RS,McGee SE,Marigold DS

更新日期：2017-01-01 00:00:00

abstract：:Similar motor regions are activated during voluntarily executed or observed movements. We investigated whether observing movements of one's own hand through a mirror will generate activations in the cortical motor regions of both the moving and nonmoving hands. Using the lateralized readiness potential (LRP), an elect...

journal_title：Journal of neurophysiology

authors： Touzalin-Chretien P,Dufour A

更新日期：2008-07-01 00:00:00

abstract：:P/Q-type voltage-dependent Ca(2+) channels (VDCCs) are highly expressed in the cerebellum, and mutations of these channels are associated with disrupted motor function. Several allelic variants of the alpha1A pore-forming subunit of P/Q-type VDCCs have been described, and mice homozygous for these mutations exhibit ga...

journal_title：Journal of neurophysiology

authors： Katoh A,Jindal JA,Raymond JL

更新日期：2007-02-01 00:00:00

abstract：:Rats typically employ 4- to 12-Hz "whisking" movements of their vibrissae during tactile exploration. The intentional sampling of signals in this frequency range suggests that neural processing of tactile information may be differentially engaged in this bandwidth. We examined action potential responses in rat primary...

journal_title：Journal of neurophysiology

authors： Garabedian CE,Jones SR,Merzenich MM,Dale A,Moore CI

更新日期：2003-09-01 00:00:00

abstract：:1. To characterize the temporal dynamic responses of ganglion cells and to define the possible inputs giving rise to their responses in catfish retina, we recorded the ganglion cell responses evoked by 1) a step of light presented in the dark, 2) an incremental and decremental step from a background illumination, and ...

journal_title：Journal of neurophysiology

authors： Sakai HM,Naka K

更新日期：1987-12-01 00:00:00

abstract：:A number of studies have indicated an important role for N-methyl-D-aspartate (NMDA) receptors in cell survival versus cell death decisions during neuronal development, trauma, and ischemia. Coupling of neurons by electrical synapses (gap junctions) is high or increases in neuronal networks during all three of these c...

journal_title：Journal of neurophysiology

authors： de Rivero Vaccari JC,Corriveau RA,Belousov AB

更新日期：2007-11-01 00:00:00

abstract：:Ipsilaterally projecting spinal excitatory interneurons (EINs) generate the hemisegmental rhythmic locomotor activity in lamprey, while the commissural interneurons ensure proper left-right alternation. 5-HT is a potent modulator of the locomotor rhythm and is endogenously released from the spinal cord during fictive ...

journal_title：Journal of neurophysiology

authors： Biró Z,Hill RH,Grillner S

更新日期：2006-08-01 00:00:00

abstract：:1. Adult rats and rats with a postnatal age of 3-29 days (PN 3-29) were used for the preparation of in vitro slices of the frontal neocortex. Epileptiform activity was induced by bath application of the gamma-aminobutyric acid-A (GABAA) receptor antagonists bicuculline or picrotoxin. 2. The voltage-sensitive dye RH 41...

journal_title：Journal of neurophysiology

authors： Sutor B,Hablitz JJ,Rucker F,ten Bruggencate G

更新日期：1994-10-01 00:00:00

abstract：:When identical stimuli are presented in rapid temporal succession, neural responses to the second stimulation are often weaker than those observed for the first. This phenomenon is termed sensory gating and is believed to be an adaptive feature that helps prevent higher-order cortical centers from being flooded with u...

journal_title：Journal of neurophysiology

authors： Arpin DJ,Gehringer JE,Wilson TW,Kurz MJ

更新日期：2017-10-01 00:00:00

abstract：:The retinal image of visual objects can vary drastically with changes of viewing angle. Nevertheless, our visual system is capable of recognizing objects fairly invariant of viewing angle. Under natural viewing conditions, different views of the same object tend to occur in temporal proximity, thereby generating tempo...

journal_title：Journal of neurophysiology

authors： Michler F,Eckhorn R,Wachtler T

更新日期：2009-08-01 00:00:00

abstract：:1. We have studied the responses of neurons in the lateral and descending vestibular nuclei of decerebrate cats to stimulation of neck receptors, produced by rotating the body in vertical planes with the head stationary. The responses to such neck stimulation were compared with the responses to vestibular stimulation ...

journal_title：Journal of neurophysiology

authors： Kasper J,Schor RH,Wilson VJ

更新日期：1988-11-01 00:00:00

abstract：:1. The preceding study described a corrective response in cats when one hind leg steps into a hole. In this investigation we examine the extent to which this behavior is organized at the spinal level by comparing the responses elicited in intact and chronic spinal cats. 2. Adult cats were trained to step bipedally wit...

journal_title：Journal of neurophysiology

authors： Hiebert GW,Gorassini MA,Jiang W,Prochazka A,Pearson KG

更新日期：1994-02-01 00:00:00

abstract：:Tetanus neurotoxin (TeNT) cleaves synaptobrevin, a protein involved in synaptic vesicle docking and fusion, thereby preventing neurotransmitter release and causing a functional deafferentation. We injected TeNT into the lateral rectus muscle of adult cats at 0.5 or 5 ng/kg (low and high dose, respectively). In the per...

journal_title：Journal of neurophysiology

authors： Gonzalez-Forero D,de la Cruz RR,Delgado-Garcia JM,Alvarez FJ,Pastor AM

更新日期：2003-04-01 00:00:00

abstract：:Augmenting (or incremental) responses are progressively growing potentials elicited by 5- to 15-Hz stimulation within the thalamus, cerebral cortex, or by setting into action reciprocal thalamocortical neuronal loops. These responses are associated with short-term plasticity processes in thalamic and cortical neurons....

journal_title：Journal of neurophysiology

authors： Timofeev I,Steriade M

更新日期：1998-05-01 00:00:00

abstract：:During walking, maintenance and coordination of activity in leg motoneurons requires intersegmental signal transfer. In a semi-intact preparation of the stick insect, we studied membrane potential modulations in mesothoracic (middle leg) motoneurons and local premotor nonspiking interneurons that were induced by stepp...

journal_title：Journal of neurophysiology

authors： Ludwar BCh,Westmark S,Büschges A,Schmidt J

更新日期：2005-10-01 00:00:00

abstract：:In experiments on slices (from 100- to 150-g Sprague-Dawley rats) kept at 33 degreesC, we studied the effects of brief hypoxia (2-3 min) on CA1 neurons. In whole cell recordings from submerged slices, with electrodes containing only KMeSO4 and N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid, and in the presence of...

journal_title：Journal of neurophysiology

authors： Erdemli G,Xu YZ,Krnjević K

更新日期：1998-11-01 00:00:00

abstract：:Humans and songbirds shape learned vocalizations during a sensorimotor sensitive period or "babbling" phase. The brain mechanisms that underlie the shaping of vocalizations by sensory feedback are not known. We examined song behavior and brain activity in zebra finches during singing as they actively shaped their song...

journal_title：Journal of neurophysiology

authors： Crandall SR,Aoki N,Nick TA

更新日期：2007-01-01 00:00:00

abstract：:Recent evidence has suggested that theta-frequency (4-7 Hz) oscillations around the human anterior cingulate cortex (ACC) and frontal cortex--that is, frontal midline theta (Fm theta) oscillations--may be involved in attentional processes in the brain. However, little is known about the physiological basis of Fm theta...

journal_title：Journal of neurophysiology

authors： Tsujimoto T,Shimazu H,Isomura Y

更新日期：2006-05-01 00:00:00

abstract：:Procedural skill learning requires iterative comparisons between feedback of self-generated motor output and a goal sensorimotor pattern. In juvenile songbirds, neural representations of both self-generated behaviors (each bird's own immature song) and the goal motor pattern (each bird's adult tutor song) are essentia...

journal_title：Journal of neurophysiology

authors： Yuan RC,Bottjer SW

更新日期：2019-02-01 00:00:00

abstract：:Membrane retrieval following exocytosis in synaptic terminals is fast and compensatory, however, little is known about the factors that regulate or contribute to this special form of endocytosis. We used whole-terminal capacitance measurements to examine the effect of hydrostatic pressure on compensatory endocytosis i...

journal_title：Journal of neurophysiology

authors： Heidelberger R,Zhou ZY,Matthews G

更新日期：2002-11-01 00:00:00

abstract：:Humans and animals value the opportunity to choose by preferring alternatives that offer more rather than fewer choices. This preference for choice may arise not only from an increased probability of obtaining preferred outcomes but also from the freedom it provides. We used human neuroimaging to investigate the neura...

journal_title：Journal of neurophysiology

authors： Fujiwara J,Usui N,Park SQ,Williams T,Iijima T,Taira M,Tsutsui K,Tobler PN

更新日期：2013-10-01 00:00:00

abstract：:Whole cell membrane currents induced by the inflammatory mediators, bradykinin, 5-hydroxytryptamine (5-HT) and prostaglandin E2, were investigated in capsaicin-sensitive dorsal root ganglion (DRG) neurons from newborn rats grown on a monolayer of hippocampal glia without nerve growth factor (NGF). When firmly attached...

journal_title：Journal of neurophysiology

authors： Vyklický L,Knotková-Urbancová H,Vitásková Z,Vlachová V,Kress M,Reeh PW

更新日期：1998-02-01 00:00:00

abstract：:The extracellular pH of living tissue in the retina and elsewhere in the brain is lower than the pH of the surrounding milieu. We have shown that the pH gradient between the in vitro retina and the superfusion solution is regulated by a circadian (24-h) clock so that it is smaller in the subjective day than in the sub...

journal_title：Journal of neurophysiology

authors： Dmitriev AV,Mangel SC

更新日期：2004-06-01 00:00:00

abstract：:Variations in cortical oscillations in the alpha (7-14 Hz) and beta (15-29 Hz) range have been correlated with attention, working memory, and stimulus detection. The mu rhythm recorded with magnetoencephalography (MEG) is a prominent oscillation generated by Rolandic cortex containing alpha and beta bands. Despite its...

journal_title：Journal of neurophysiology

authors： Jones SR,Pritchett DL,Sikora MA,Stufflebeam SM,Hämäläinen M,Moore CI

更新日期：2009-12-01 00:00:00

abstract：:Visual response properties of neurons in the dorsolateral geniculate nucleus (dLGN) have been well described in several species, but not in rats. Analysis of responses from the unanesthetized rat dLGN will be needed to develop quantitative models that account for visual behavior of rats. We recorded visual responses f...

journal_title：Journal of neurophysiology

authors： Sriram B,Meier PM,Reinagel P

更新日期：2016-06-01 00:00:00

abstract：:1. An electrophysiological study of the D-glucose sensitivity of X-organ (XO) neurosecretory cell bodies in crayfish was carried out with the use of microelectrodes, perforated, and cell-attached patch-clamp techniques. 2. Glucose depolarizes the membrane potential of XO cells in a concentration-dependent manner. 3. D...

journal_title：Journal of neurophysiology

authors： García E,Benítez A,Onetti CG

更新日期：1993-08-01 00:00:00

abstract：:1. Neurons in the ventral intraparietal area (VIP) are known to respond to translating random dot patterns. Such responses can be explained on the basis of the input of the middle temporal area (MT) to this area. Anatomic evidence has shown that VIP receives input from the dorsal part of the medial superior temporal a...

journal_title：Journal of neurophysiology

authors： Schaafsma SJ,Duysens J

更新日期：1996-12-01 00:00:00