Motor deficits in homozygous and heterozygous p/q-type calcium channel mutants.

abstract：:Active sensing in biological system consists of emitting/receiving a periodic signal to explore the environment. The signal can be emitted toward distant objects, as in echolocation, or in direct contact with the object, for example, whisking in rodents. We explored the hypothesis that a similar mechanism exists in hu...

journal_title：Journal of neurophysiology

authors： Dione M,Wessberg J

更新日期：2019-09-01 00:00:00

abstract：:1. There is a long-standing debate about whether the large spiny cells in the hilar region of the hippocampus should be classified as pyramidal cells of Ammon's horn or as a distinct cell type of the dentate gyrus. The rationale for grouping these hilar neurons (termed "mossy cells") with pyramidal cells of Ammon's ho...

journal_title：Journal of neurophysiology

authors： Buckmaster PS,Strowbridge BW,Schwartzkroin PA

更新日期：1993-10-01 00:00:00

abstract：:In the oscillatory circuits known as central pattern generators (CPGs), most synaptic connections are inhibitory. We have assessed the effects of inhibitory synaptic input on the dynamic behavior of a component neuron of the pyloric CPG in the lobster stomatogastric ganglion. Experimental perturbations were applied to...

journal_title：Journal of neurophysiology

authors： Elson RC,Huerta R,Abarbanel HD,Rabinovich MI,Selverston AI

更新日期：1999-07-01 00:00:00

abstract：:The rostral ventromedial medulla (RVM) modulates nociception through changes in the activity of two classes of neuron, ON- and OFF-cells. The activity of these neurons is regulated, in part, by input from the periaqueductal gray (PAG). The objective of this study was to determine whether PAG-mediated antinociception i...

journal_title：Journal of neurophysiology

authors： Tortorici V,Morgan MM

更新日期：2002-10-01 00:00:00

abstract：:1. In the intact cat eye, the responses of ganglion cells to light stimulation were recorded extracellularly and the actions of iontophoretically applied 2-amino-4-phosphonobutyrate (APB), a potent agonist at ON-bipolars, and of strychnine, a glycine antagonist, were investigated. 2. Under light-adapted conditions, th...

journal_title：Journal of neurophysiology

authors： Müller F,Wässle H,Voigt T

更新日期：1988-06-01 00:00:00

abstract：:1. The cochlear nucleus of rat brain stem slices was explored with extracellular microelectrodes to determine the distribution and characteristics of spontaneously active neurons. 2. In mapping experiments few spontaneously active neurons were found in anteroventral or posteroventral divisions of the cochlear nucleus....

journal_title：Journal of neurophysiology

authors： Waller HJ,Godfrey DA

更新日期：1994-02-01 00:00:00

abstract：:1. Eleven adult cats were trained to stop inspiration in response to a conditioning stimulus. The conditioning stimuli were presented at the onset of inspiration at intervals of approximately 20-30 s. Intratracheal pressures, diaphragmatic activity, and the extracellular activity of single medullary respiratory neuron...

journal_title：Journal of neurophysiology

authors： Orem J

更新日期：1989-11-01 00:00:00

abstract：:The intermediate and deep layers of the monkey superior colliculus (SC) are known to be important for the generation of saccadic eye movements. Recent studies have also provided evidence that the rostral SC might be involved in the control of pursuit eye movements. However, because rostral SC neurons respond to visual...

journal_title：Journal of neurophysiology

authors： Krauzlis RJ

更新日期：2001-11-01 00:00:00

abstract：:The core region of primate auditory cortex contains a primary and two primary-like fields (AI, primary auditory cortex; R, rostral field; RT, rostrotemporal field). Although it is reasonable to assume that multiple core fields provide an advantage for auditory processing over a single primary field, the differential r...

journal_title：Journal of neurophysiology

authors： Bendor D,Wang X

更新日期：2008-08-01 00:00:00

abstract：:N-Acetylaspartylglutamate (NAAG) is an agonist at the type 3 metabotropic glutamate receptor (mGluR3), which is coupled to a Gi/o protein. When activated, the mGluR3 receptor inhibits adenylyl cyclase and reduces the cAMP-mediated second-messenger cascade. Long-term potentiation (LTP) in the medial perforant path (MPP...

journal_title：Journal of neurophysiology

authors： Lea PM 4th,Wroblewska B,Sarvey JM,Neale JH

更新日期：2001-03-01 00:00:00

abstract：:Whole cell membrane currents induced by the inflammatory mediators, bradykinin, 5-hydroxytryptamine (5-HT) and prostaglandin E2, were investigated in capsaicin-sensitive dorsal root ganglion (DRG) neurons from newborn rats grown on a monolayer of hippocampal glia without nerve growth factor (NGF). When firmly attached...

journal_title：Journal of neurophysiology

authors： Vyklický L,Knotková-Urbancová H,Vitásková Z,Vlachová V,Kress M,Reeh PW

更新日期：1998-02-01 00:00:00

abstract：:Spontaneous and stimulus-evoked excitatory postsynaptic currents (EPSCs) were recorded in calyx nerve terminals from the turtle vestibular lagena to quantify key attributes of quantal transmission at this synapse. On average, EPSC events had a magnitude of ∼ 42 pA, a rise time constant of τ(0) ∼ 229 μs, decayed to bas...

journal_title：Journal of neurophysiology

authors： Highstein SM,Mann MA,Holstein GR,Rabbitt RD

更新日期：2015-06-01 00:00:00

abstract：:1. Neuron-specific expression of alternately spliced exons of the gene encoding the Phe-Met-Arg-Phe-NH2 (FMRFamide) family of neuropeptides and the role of encoded peptides in synaptic transmission were examined in an identified cardiorespiratory interneuron, the visceral white interneuron (VWI), in the snail Lymnaea....

journal_title：Journal of neurophysiology

authors： Skingsley DR,Bright K,Santama N,van Minnen J,Brierley MJ,Burke JF,Benjamin PR

更新日期：1993-03-01 00:00:00

abstract：:The purpose of our study was to examine the associations between the performance of older adults on four tests of mobility and the physical capabilities of the lower leg muscles. The assessments included measures of muscle strength, muscle activation, and perceived fatigability. Muscle activation was quantified as the...

journal_title：Journal of neurophysiology

authors： Mani D,Almuklass AM,Hamilton LD,Vieira TM,Botter A,Enoka RM

更新日期：2018-10-01 00:00:00

abstract：:The contribution of ascending afferents to the control of speech movement was evaluated by applying unanticipated loads to the lower lip during the generation of combined upper lip-lower lip speech gestures. To eliminate potential contamination due to anticipation or adaptation, loads were applied randomly on only 10-...

journal_title：Journal of neurophysiology

authors： Abbs JH,Gracco VL

更新日期：1984-04-01 00:00:00

abstract：:We compared electroretinographic (ERG) responses to uniform-field and a variety of pattern stimuli using both transient and steady-state analyses. Evidence is provided that for all of these stimuli, the peak at high temporal frequencies in the steady-state response corresponds to the fast wave of the transient respons...

journal_title：Journal of neurophysiology

authors： Baker CL Jr,Hess RF

更新日期：1984-05-01 00:00:00

abstract：:Humans with spinal cord injury (SCI) modulate locomotor output in response to limb load. Understanding the neural control mechanisms responsible for locomotor adaptation could provide a framework for selecting effective interventions. We quantified feedback and feedforward locomotor adaptations to limb load modulation...

journal_title：Journal of neurophysiology

authors： Gordon KE,Wu M,Kahn JH,Schmit BD

更新日期：2010-09-01 00:00:00

abstract：:Neurons constituting the pacemaker of circadian rhythms, located in the suprachiasmatic nucleus, generate spontaneous firing patterns that change across the day-night cycle. Their average spontaneous firing rate is considered an important functional marker of clock activity because it is highest during daytime and low...

journal_title：Journal of neurophysiology

authors： Pennartz CM,Bierlaagh MA,Geurtsen AM

更新日期：1997-10-01 00:00:00

abstract：:1. Single-unit recordings were made, under moderate gaseous anesthesia (33% O2-66% N2O + 0.5/0.6% halothane), in the ventrobasal (VB) thalamic complex of rats (n = 42) with a mononeuropathy created 2-3 wk beforehand, by four loose ligatures around the common sciatic nerve. Before the recording session, three behaviora...

journal_title：Journal of neurophysiology

authors： Guilbaud G,Benoist JM,Jazat F,Gautron M

更新日期：1990-11-01 00:00:00

abstract：:Trace eyeblink classical conditioning (tEBCC) can be accelerated by making training trials contingent on the naturally generated hippocampal 3- to 7-Hz theta rhythm. However, it is not well-understood how the presence (or absence) of theta affects stimulus-driven changes within the hippocampus and how it correlates wi...

journal_title：Journal of neurophysiology

authors： Darling RD,Takatsuki K,Griffin AL,Berry SD

更新日期：2011-05-01 00:00:00

abstract：:1. We present a new mathematical description of the complete distribution of electrical responses to stochastic synaptic activity (quantal analysis) that is intended as a model of experiments on central neuronal synapses. Unlike previous treatments, this distribution is calculated for each instant after the release of...

journal_title：Journal of neurophysiology

authors： Blum KI,Idiart MA

更新日期：1994-09-01 00:00:00

abstract：:Surface electromyograms (EMG) and force were recorded during repeated involuntary spasms of paralyzed triceps surae muscles of four men with chronic cervical spinal cord injury. The firing rates of 78 medial gastrocnemius (MG) motor units also were recorded intramuscularly with tungsten microelectrodes. Spasms typical...

journal_title：Journal of neurophysiology

authors： Thomas CK,Ross BH

更新日期：1997-05-01 00:00:00

abstract：:Perceptual decision making is often modeled as perfect integration of sequential sensory samples until the accumulated total reaches a fixed decision bound. In that view, the buildup of neural activity during perceptual decision making is attributed to temporal integration. However, an alternative explanation is that ...

journal_title：Journal of neurophysiology

authors： Carland MA,Marcos E,Thura D,Cisek P

更新日期：2016-02-01 00:00:00

abstract：:Single, teased fiber recordings were made from the decentralized right cervical vagus nerve (hyponodal) of the rat. A total of 67 afferent fibers that responded to gastric distension (GD) were studied: 9 fibers were stimulated by phasic balloon GD, 58 by more natural fluid GD. All balloon GD-responsive fibers had rest...

journal_title：Journal of neurophysiology

authors： Ozaki N,Sengupta JN,Gebhart GF

更新日期：1999-11-01 00:00:00

abstract：:Regulation of feeding behavior involves the integration of multiple physiological and neurological pathways that control both nutrient-seeking and consummatory behaviors. The consummatory phase of ingestion includes stereotyped oromotor movements of the tongue and jaw that are controlled through brain stem pathways. T...

journal_title：Journal of neurophysiology

authors： Nasse JS,Travers JB

更新日期：2014-08-01 00:00:00

abstract：:Transcranial DC stimulation (tDCS) induces stimulation polarity-dependent neuroplastic excitability shifts in the human brain. Because it accomplishes long-lasting effects and its application is simple, it is used increasingly. However, one drawback is its low focality, caused by 1) the large stimulation electrode and...

journal_title：Journal of neurophysiology

authors： Nitsche MA,Doemkes S,Karaköse T,Antal A,Liebetanz D,Lang N,Tergau F,Paulus W

更新日期：2007-04-01 00:00:00

abstract：:Using extra- and intracellular recording techniques, we investigated the epileptiform activity induced by low concentrations (5 and 10 microM) of bath-applied 4-aminopyridine (4-AP) in the CA3 subfield of rat hippocampal slices. We also studied the effects of 4-AP on the excitatory and inhibitory synaptic conductance ...

journal_title：Journal of neurophysiology

authors： Rutecki PA,Lebeda FJ,Johnston D

更新日期：1987-06-01 00:00:00

abstract：:Dual whole cell patch-clamp recordings in rat nucleus accumbens, the main component of the ventral striatum, were made to assess the presence of synaptic interconnections between medium-sized spiny neurons, a group of GABAergic and peptidergic neurons that constitute the principal cells of the striatum. Neurons were s...

journal_title：Journal of neurophysiology

authors： Taverna S,van Dongen YC,Groenewegen HJ,Pennartz CM

更新日期：2004-03-01 00:00:00

abstract：:Fast inhibitory synaptic transmission in the brain relies on ionotropic GABA(A) receptors (GABA(A)R). Eighteen genes code for GABA(A)R subunits, but little is known about the epsilon subunit. Our aim was to identify the synaptic transmission properties displayed by native receptors incorporating epsilon. Immunogold lo...

journal_title：Journal of neurophysiology

authors： Belujon P,Baufreton J,Grandoso L,Boué-Grabot E,Batten TF,Ugedo L,Garret M,Taupignon AI

更新日期：2009-10-01 00:00:00

abstract：:Neurons in the primate extrastriate cortex are highly selective for complex stimulus features such as faces, objects, and motion patterns. One explanation for this selectivity is that neurons in these areas carry out sophisticated computations on the outputs of lower-level areas such as primary visual cortex (V1), whe...

journal_title：Journal of neurophysiology

authors： Tsui JM,Hunter JN,Born RT,Pack CC

更新日期：2010-06-01 00:00:00