Cellular mechanisms underlying spontaneous firing in rat suprachiasmatic nucleus: involvement of a slowly inactivating component of sodium current.

abstract：:Recent work in the anterior piriform cortex (aPCX) has demonstrated that cortical odor receptive fields are highly dynamic, showing rapid changes of both firing rate and temporal patterning within relatively few inhalations of an odor, despite relatively maintained, patterned input from olfactory bulb mitral/tufted ce...

journal_title：Journal of neurophysiology

authors： Wilson DA

更新日期：2000-12-01 00:00:00

abstract：:Current and voltage-clamp recordings were made at room temperature from cultured mouse spinal neurons using conventional two-electrode voltage-clamp techniques and electrodes filled with either 3 M KCl, 3 M CsCl, or 3 M Cs2SO4. In the presence of tetraethylammonium and tetrodotoxin, "fast" (rapidly rising and falling)...

journal_title：Journal of neurophysiology

authors： Owen DG,Segal M,Barker JL

更新日期：1986-06-01 00:00:00

abstract：:Several qualitative features distinguish bipedal from quadrupedal locomotion in mammals. In this study we show quantitative differences between quadrupedal and bipedal gait in the Japanese monkey in terms of gait patterns, trunk/hindlimb kinematics, and electromyographic (EMG) activity, obtained from 3 macaques during...

journal_title：Journal of neurophysiology

authors： Higurashi Y,Maier MA,Nakajima K,Morita K,Fujiki S,Aoi S,Mori F,Murata A,Inase M

更新日期：2019-07-01 00:00:00

abstract：:We previously reported that neurons in the mediodorsal thalamic nucleus (MD) are topographically organized and express spatial and nonspatial coding properties similar to those of the prefrontal areas with which they are connected. In the course of mapping the dorsal thalamus, we also studied neurons in a subset of th...

journal_title：Journal of neurophysiology

authors： Tanibuchi I,Goldman-Rakic PS

更新日期：2005-01-01 00:00:00

abstract：:To investigate the nature of the visuomotor transformation, previous studies have used pointing tasks and examined how adaptation to a spatially localized mismatch between vision and proprioception generalizes across the workspace. Whereas some studies found extensive spatial generalization of single-point remapping, ...

journal_title：Journal of neurophysiology

authors： Malfait N,Henriques DY,Gribble PL

更新日期：2008-01-01 00:00:00

abstract：:Previous research using a loud acoustic stimulus (LAS) to investigate motor preparation in reaction time (RT) tasks indicates that responses can be triggered well in advance of the presentation of an imperative stimulus (IS). This is intriguing given that high levels of response preparation cannot be maintained for lo...

journal_title：Journal of neurophysiology

authors： Marinovic W,de Rugy A,Lipp OV,Tresilian JR

更新日期：2013-02-01 00:00:00

abstract：:We have examined the spatial integration properties of complex cells to determine whether some of their responses can be described by a maximum operation (MAX)-like computation, as suggested by Riesenhuber and Poggio's model of object recognition. Membrane potential was recorded from anesthetized cats while optimally ...

journal_title：Journal of neurophysiology

authors： Lampl I,Ferster D,Poggio T,Riesenhuber M

更新日期：2004-11-01 00:00:00

abstract：:The turtle posterior crista consists of two hemicristae. Each hemicrista extends from the planum semilunatum to the nonsensory torus and includes a central zone (CZ) surrounded by a peripheral zone (PZ). Type I and type II hair cells are found in the CZ and are innervated by calyx, dimorphic and bouton afferents. Only...

journal_title：Journal of neurophysiology

authors： Brichta AM,Goldberg JM

更新日期：2000-03-01 00:00:00

abstract：:Attention is thought to improve most aspects of perception. However, we recently showed that, somewhat surprisingly, endogenous attention can also lead to low subjective perceptual ratings (Rahnev et al., 2011). Here we investigated the neural basis of this effect and tested whether spontaneous fluctuations of the att...

journal_title：Journal of neurophysiology

authors： Rahnev DA,Bahdo L,de Lange FP,Lau H

更新日期：2012-09-01 00:00:00

abstract：:Altered activity of the entopeduncular nucleus, the rodent homologue of the globus pallidus internal segment in primates, is thought to mediate behavioral consequences of midbrain dopamine depletion in rodents. Few studies, however, have examined dopaminergic modulation of spiking activity in this nucleus. This study ...

journal_title：Journal of neurophysiology

authors： Ruskin DN,Bergstrom DA,Walters JR

更新日期：2002-07-01 00:00:00

abstract：:L-type calcium channels couple membrane depolarization in neurons to numerous processes including gene expression, synaptic efficacy, and cell survival. To establish the contribution of L-type calcium channels to various signaling cascades, investigators have relied on their unique pharmacological sensitivity to dihyd...

journal_title：Journal of neurophysiology

authors： Lipscombe D,Helton TD,Xu W

更新日期：2004-11-01 00:00:00

abstract：:Studies on generalization show the nature of how learning is encoded in the brain. Previous studies have shown rather limited generalization of dynamics learning across changes in movement direction, a finding that is consistent with the idea that learning is primarily local. In contrast, studies show a broader patter...

journal_title：Journal of neurophysiology

authors： Mattar AA,Ostry DJ

更新日期：2010-07-01 00:00:00

abstract：:1. The discharge patterns of 40 neurons in the central nucleus of the inferior colliculus (ICC) of the chinchilla were evaluated before and after acute cochlea trauma from intense tone exposure. Single-unit recordings were obtained from neurons in the ICC contralateral to the sound-stimulated ear. Cochlear trauma was ...

journal_title：Journal of neurophysiology

authors： Wang J,Salvi RJ,Powers N

更新日期：1996-01-01 00:00:00

abstract：:Recent evidence suggests that changes in sodium channel expression and localization may be involved in some pathological pain syndromes. SNS, a tetrodotoxin-resistant (TTX-R) sodium channel, is preferentially expressed in small dorsal root ganglion (DRG) neurons, many of which are nociceptive. TTX-R sodium currents an...

journal_title：Journal of neurophysiology

authors： Fjell J,Cummins TR,Fried K,Black JA,Waxman SG

更新日期：1999-02-01 00:00:00

abstract：:The cerebellum of the mormyrid fish consists of three major divisions: the valvula, the central lobes, and the caudal lobes. Several studies have focused on the central lobes and the valvula, but little is known about the caudal lobes. The mormyrid caudal lobe includes anterior and posterior components. The anterior c...

journal_title：Journal of neurophysiology

authors： Zhang Y,Han VZ

更新日期：2007-09-01 00:00:00

abstract：:1. Areas of cerebellar cortex related to saccadic eye movements were ablated in three Macaca mulatta monkeys trained to fixate visual targets. There followed a postoperative dysmetria of saccadic eye movements which appeared to be the result of an impairment specifically within the saccadic system. 2. Convergent evide...

journal_title：Journal of neurophysiology

authors： Ritchie L

更新日期：1976-11-01 00:00:00

abstract：:Primate head-free saccade generator implements a desired (post-VOR) eye position command by anticipating intended head motion. J. Neurophysiol. 78: 2811-2816, 1997. When we glance between objects, the brain ultimately controls gaze direction in space. However, it is currently unclear how this is allocated into separat...

journal_title：Journal of neurophysiology

authors： Crawford JD,Guitton D

更新日期：1997-11-01 00:00:00

abstract：:A total of 443 pelvic nerve afferent fibers in the L6 dorsal root of the rat were identified by electrical stimulation of the pelvic nerve; 319 (72%) were myelinated A delta fibers with a mean conduction velocity (CV) of 11.8 m/s and 124 (28%) were unmyelinated C fibers with mean CV of 1.9 m/s. Two hundred fifty-two f...

journal_title：Journal of neurophysiology

authors： Su X,Sengupta JN,Gebhart GF

更新日期：1997-03-01 00:00:00

abstract：:The auditory frequency-following response (FFR) reflects synchronized and phase-locked activity along the auditory pathway in response to sound. Although FFRs were historically thought to reflect subcortical activity, recent evidence suggests an auditory cortex contribution as well. Here we present electrophysiologica...

journal_title：Journal of neurophysiology

authors： White-Schwoch T,Anderson S,Krizman J,Nicol T,Kraus N

更新日期：2019-08-01 00:00:00

abstract：:Whole cell and cell-attached patch-clamp techniques characterized the neurosteroid anesthetic alphaxalone's (5alpha-pregnane-3alpha-ol-11,20-dione) effects on GABAA receptors and on Cl- currents in cultured embryonic (5- to 8-wk old) human dorsal root ganglion neurons. Alphaxalone applied by pressure pulses from close...

journal_title：Journal of neurophysiology

authors： Valeyev AY,Hackman JC,Holohean AM,Wood PM,Katz JL,Davidoff RA

更新日期：1999-07-01 00:00:00

abstract：:Individuals with cerebral palsy (CP) experience impairments in the control of head and neck movements, suggesting dysfunction in brain stem circuitry. To examine if brain stem circuitry is altered in CP, we compared reflexes evoked in the sternocleidomastoid (SCM) muscle by trigeminal nerve stimulation in adults with ...

journal_title：Journal of neurophysiology

authors： Smith AT,Gorassini MA

更新日期：2018-09-01 00:00:00

abstract：:1. Single-unit recordings were made, under moderate gaseous anesthesia (33% O2-66% N2O + 0.5/0.6% halothane), in the ventrobasal (VB) thalamic complex of rats (n = 42) with a mononeuropathy created 2-3 wk beforehand, by four loose ligatures around the common sciatic nerve. Before the recording session, three behaviora...

journal_title：Journal of neurophysiology

authors： Guilbaud G,Benoist JM,Jazat F,Gautron M

更新日期：1990-11-01 00:00:00

abstract：:It is well established that orderly patterns of motor neuron activity, muscle recruitment, and limb movement are generated in chicks during motility by embryonic day (E)9, the midpoint in embryonic development. However, our recent work suggests that some attributes of motility, such as the rhythm of repetitive limb mo...

journal_title：Journal of neurophysiology

authors： Bradley NS,Jahng DY

更新日期：2003-09-01 00:00:00

abstract：:The effects of neuronal density on morphological and functional attributes of the evolving networks were studied in cultured dissociated hippocampal neurons. Plating at different densities affected connectivity among the neurons, such that sparse networks exhibited stronger synaptic connections between pairs of record...

journal_title：Journal of neurophysiology

authors： Ivenshitz M,Segal M

更新日期：2010-08-01 00:00:00

abstract：:The ablation of afferent input results in the reorganization of sensory and motor cortices. In the primary visual cortex (V1), binocular retinal lesions deprive a corresponding cortical region [lesion projection zone (LPZ)] of visual input. Nevertheless, neurons in the LPZ regain responsiveness by shifting their recep...

journal_title：Journal of neurophysiology

authors： McManus JN,Ullman S,Gilbert CD

更新日期：2008-05-01 00:00:00

abstract：:Single neurons were recorded from the ventral posteromedial thalamic nucleus (VPM) of urethan-anesthetized rats. Six of these animals were intact, 28 sustained kainic acid (KA) lesions of trigeminal nucleus principalis (PrV), and 9 received similar lesions of trigeminal subnucleus interpolaris (SpVi). Four animals sus...

journal_title：Journal of neurophysiology

authors： Rhoades RW,Belford GR,Killackey HP

更新日期：1987-05-01 00:00:00

abstract：:Neurons in the macaque supplementary eye field (SEF) fire at different rates in conjunction with planning saccades in different directions. They also exhibit object-centered spatial selectivity, firing at different rates when the target of the saccade is at the left or right end of a horizontal bar. To compare the rat...

journal_title：Journal of neurophysiology

authors： Moorman DE,Olson CR

更新日期：2007-05-01 00:00:00

abstract：:Multisite optical recording has revealed that the neural excitation wave induced by a sensory stimulation begins at a focus and propagates in the cortex. This wave is considered to be important for computation in the sensory cortex, particularly the integration of sensory information; however, the nature of this wave ...

journal_title：Journal of neurophysiology

authors： Hama N,Kawai M,Ito SI,Hirota A

更新日期：2018-05-01 00:00:00

abstract：:A number of studies have indicated an important role for N-methyl-D-aspartate (NMDA) receptors in cell survival versus cell death decisions during neuronal development, trauma, and ischemia. Coupling of neurons by electrical synapses (gap junctions) is high or increases in neuronal networks during all three of these c...

journal_title：Journal of neurophysiology

authors： de Rivero Vaccari JC,Corriveau RA,Belousov AB

更新日期：2007-11-01 00:00:00

abstract：:M current relaxations recorded in PC12 cells were subjected to nonstationary noise analysis (NSNA) to obtain estimates of single-channel current (i), channel number (N), and open probability (Po) for the channels responsible for M current. The analysis was constrained such that N and single-channel conductance were th...

journal_title：Journal of neurophysiology

authors： Villarroel A

更新日期：1997-04-01 00:00:00