Neuronal density determines network connectivity and spontaneous activity in cultured hippocampus.

abstract：:Single-unit electrical activity has been recorded from 122 viscerosomatic neurons in the T9 and T11 segments of the cat's spinal cord. These neurons were excited by electrical and/or natural stimulation of visceral and somatic afferent fibers. The majority of viscerosomatic neurons (72%) received somatic nociceptive i...

journal_title：Journal of neurophysiology

authors： Tattersall JE,Cervero F,Lumb BM

更新日期：1986-09-01 00:00:00

abstract：:Because smooth-pursuit eye movements (SPEM) can be executed only in the presence of a moving target, it has been difficult to attribute the neuronal activity observed during the execution of these eye movements to either sensory processing or to motor preparation or execution. Previously, we showed that rhesus monkeys...

journal_title：Journal of neurophysiology

authors： Ilg UJ,Thier P

更新日期：2003-09-01 00:00:00

abstract：:The goal of this study was to characterize the effects of corticotrophin-releasing factor (CRF) on rat paraventricular nucleus (PVN) putative parvocellular neurons using whole cell patch-clamp recordings and single-cell reverse transcription-multiplex polymerase chain reaction (single-cell RT-mPCR) techniques. Under c...

journal_title：Journal of neurophysiology

authors： Qiu DL,Chu CP,Shirasaka T,Tsukino H,Nakao H,Kato K,Kunitake T,Katoh T,Kannan H

更新日期：2005-07-01 00:00:00

abstract：:1. The effect of cholinergic receptor activation on gamma-aminobutyric acid (GABA)-mediated inhibitory synaptic transmission was investigated in voltage-clamped CA1 pyramidal neurons (HPNs) in the guinea pig hippocampal slice preparation. 2. The cholinergic agonist carbachol (1-10 microM) induced a prominent and susta...

journal_title：Journal of neurophysiology

authors： Behrends JC,ten Bruggencate G

更新日期：1993-02-01 00:00:00

abstract：:While the effects of sensory feedback on bimanual tasks have been studied extensively at two ends of the motor control hierarchy, the cortical and behavioral levels, much less is known about how it affects the intermediate levels, including neural control of homologous muscle groups. We investigated the effects of som...

journal_title：Journal of neurophysiology

authors： Nguyen HB,Lee SW,Harris-Love ML,Lum PS

更新日期：2017-02-01 00:00:00

abstract：:The neuronal mechanism which gives rise to the synchronization of motor-unit discharges has been inferred from an analysis of the interspike intervals of individual motor-unit discharges recorded from the soleus muscle. The motor units were divided into two groups on the basis of characteristic changes in their spike ...

journal_title：Journal of neurophysiology

authors： Mori S

更新日期：1975-07-01 00:00:00

abstract：:Natural visual scenes are cluttered. In such scenes, many objects in the periphery can be crowded, blocked from identification, simply because of the dense array of clutter. Outside of the fovea, crowding constitutes the fundamental limitation on object recognition and is thought to arise from the limited resolution o...

journal_title：Journal of neurophysiology

authors： Fischer J,Whitney D

更新日期：2011-09-01 00:00:00

abstract：:Recent studies have pointed to olfactory system beta oscillations of the local field potential (15-30 Hz) and their roles both in learning and as specific responses to predator odors. To describe odorant physical properties, resultant behavioral responses and changes in the central olfactory system that may induce the...

journal_title：Journal of neurophysiology

authors： Lowry CA,Kay LM

更新日期：2007-07-01 00:00:00

abstract：:1. A total of 312 cutaneous afferent units identified in the rat foot as belonging to one of nine major types of sensory receptors were included in the present study. A natural stimulus set was defined to differentiate optimally among those receptor types according to the distinguishing response patterns that it produ...

journal_title：Journal of neurophysiology

authors： Leem JW,Willis WD,Weller SC,Chung JM

更新日期：1993-12-01 00:00:00

abstract：:Field potential recording was used to investigate properties of synaptic transmission and long-term potentiation (LTP) at Schaffer collateral-CA1 synapses in both hippocampal slices of mutant mice in which the alpha-subunit of the olfactory cyclic nucleotide-gated channel (alpha3/OCNC)1 was rendered null and also in s...

journal_title：Journal of neurophysiology

authors： Parent A,Schrader K,Munger SD,Reed RR,Linden DJ,Ronnett GV

更新日期：1998-06-01 00:00:00

abstract：:The responses of sustaining and dimming fibers were characterized by the time varying firing rates elicited by extrinsic current and flashes of light. These data were simulated by an adaptive integrate-and-fire model. A postimpulse shunt conductance simulated spike-frequency adaptation. The correlation between observe...

journal_title：Journal of neurophysiology

authors： Glantz RM,Schroeter JP

更新日期：2004-07-01 00:00:00

abstract：:The vestibular system operates in a push-pull fashion using signals from both labyrinths and an intricate bilateral organization. Unilateral vestibular lesions cause well-characterized motor deficits that are partially compensated over time and whose neural correlates have been traced in the mean response modulation o...

journal_title：Journal of neurophysiology

authors： Yu XJ,Thomassen JS,Dickman JD,Newlands SD,Angelaki DE

更新日期：2014-08-15 00:00:00

abstract：:1. We studied the organization of motor units in the tenuissimus (TEN) muscle of pentobarbital-anesthetized cats. The cat TEN is a long, delicate straplike muscle that spans hip and knee, which has a very flat length-tension curve through 22 mm of length change. 2. The TEN motor nucleus, labeled by retrograde transpor...

journal_title：Journal of neurophysiology

authors： Lev-Tov A,Pratt CA,Burke RE

更新日期：1988-04-01 00:00:00

abstract：:Echolocating bats use echoes of their sonar emissions to determine the position and distance of objects or prey. Target distance is represented as a map of echo delay in the auditory cortex (AC) of bats. During a bat's flight through a natural complex environment, echo streams are reflected from multiple objects along...

journal_title：Journal of neurophysiology

authors： Greiter W,Firzlaff U

更新日期：2017-06-01 00:00:00

abstract：:Iontophoresis of glutamate at sites on the apical dendrite 278-555 microm from the somata of rat neocortical pyramidal neurons evoked low-threshold, small, slow spikes and/or large, fast spikes in 71% of recorded cells. The amplitude of the small, slow spikes recorded at the soma averaged 9.1 mV, and their apparent th...

journal_title：Journal of neurophysiology

authors： Schwindt PC,Crill WE

更新日期：1997-05-01 00:00:00

abstract：:The widespread noradrenergic innervation in the brain promotes arousal and learning by molecular mechanisms that remain largely undefined. Recent work shows that the β(2)-adrenergic receptor (β(2)AR) is linked to the AMPA-type glutamate receptor subunit GluA1 via stargazin and PSD-95 (Joiner ML, Lise MF, Yuen EY, Kam ...

journal_title：Journal of neurophysiology

authors： Qian H,Matt L,Zhang M,Nguyen M,Patriarchi T,Koval OM,Anderson ME,He K,Lee HK,Hell JW

更新日期：2012-05-01 00:00:00

abstract：:Neurons in area MT, a motion-sensitive area of extrastriate cortex, respond to a step of target velocity with a transient-sustained firing pattern. The transition from a high initial firing rate to a lower sustained rate occurs over a time course of 20-80 ms and is considered a form of short-term adaptation. The prese...

journal_title：Journal of neurophysiology

authors： Priebe NJ,Churchland MM,Lisberger SG

更新日期：2002-07-01 00:00:00

abstract：:The increasing use of transgenic mice for the study of pain mechanisms necessitates comprehensive understanding of the murine somatosensory system. Using an in vivo mouse preparation, we studied response properties of tibial nerve afferent fibers innervating glabrous skin. Recordings were obtained from 225 fibers iden...

journal_title：Journal of neurophysiology

authors： Cain DM,Khasabov SG,Simone DA

更新日期：2001-04-01 00:00:00

abstract：:Sopite syndrome, centered around the drowsiness, lethargy, and irritability associated with motion sickness, can be induced by exposure to low-frequency motion. It is known that the vestibular apparatus plays an important role in the pathogenesis of motion sickness, which features several autonomic responses, and we h...

journal_title：Journal of neurophysiology

authors： Foster M,Singh N,Kwok K,Macefield VG

更新日期：2020-12-01 00:00:00

abstract：:Activity-dependent developmental maturation of the neocortical network is thought to involve the stabilization and potentiation of immature synapses. In particular, N-methyl-d-aspartate (NMDA) receptor-dependent long-term plasticity that is expressed presynaptically appears to be crucial for the selection of functiona...

journal_title：Journal of neurophysiology

authors： Walz C,Jüngling K,Lessmann V,Gottmann K

更新日期：2006-12-01 00:00:00

abstract：:1. The effects of inhibitory amino acid transmitters on horizontal cells in the superfused amphibian retina were studied by the use of conventional intracellular recording techniques. 2. Gamma-aminobutyric acid (GABA) caused a calcium-independent depolarization of horizontal cells in mud puppy and tiger salamander. Th...

journal_title：Journal of neurophysiology

authors： Stockton RA,Slaughter MM

更新日期：1991-03-01 00:00:00

abstract：:N-methyl-d-aspartate receptors (NMDARs) are fundamental coincidence detectors of synaptic activity necessary for the induction of synaptic plasticity and synapse stability. Adjusting NMDAR synaptic content, whether by receptor insertion or lateral diffusion between extrasynaptic and synaptic compartments, could play a...

journal_title：Journal of neurophysiology

authors： McQuate A,Barria A

更新日期：2020-03-01 00:00:00

abstract：:Early visual motion signals are local and one-dimensional (1-D). For specification of global two-dimensional (2-D) motion vectors, the visual system should appropriately integrate these signals across orientation and space. Previous neurophysiological studies have suggested that this integration process consists of tw...

journal_title：Journal of neurophysiology

authors： Amano K,Takeda T,Haji T,Terao M,Maruya K,Matsumoto K,Murakami I,Nishida S

更新日期：2012-06-01 00:00:00

abstract：:Neurons of the avian nucleus laminaris (NL) compute the interaural time difference (ITD) by detecting coincident arrivals of binaural signals with submillisecond accuracy. The cellular mechanisms for this temporal precision have long been studied theoretically and experimentally. The myelinated axon initial segment in...

journal_title：Journal of neurophysiology

authors： Ashida G,Abe K,Funabiki K,Konishi M

更新日期：2007-03-01 00:00:00

abstract：:Gain-of-function missense mutations in voltage-gated sodium channel Nav1.7 have been linked to small-fiber neuropathy, which is characterized by burning pain, dysautonomia and a loss of intraepidermal nerve fibers. However, the mechanistic cascades linking Nav1.7 mutations to axonal degeneration are incompletely under...

journal_title：Journal of neurophysiology

authors： Estacion M,Vohra BP,Liu S,Hoeijmakers J,Faber CG,Merkies IS,Lauria G,Black JA,Waxman SG

更新日期：2015-09-01 00:00:00

abstract：:1. The inhibitory response of exogenously applied glycine was investigated in freshly dissociated rat nucleus tractus solitarii neurons under whole cell configuration using new perforated patch-clamp technique termed "gramicidin perforated patch technique," which maintains intact intracellular Cl- concentrations. 2. U...

journal_title：Journal of neurophysiology

authors： Rhee JS,Ebihara S,Akaike N

更新日期：1994-09-01 00:00:00

abstract：:The visual world presents multiple potential targets that can be brought to the fovea by saccadic eye movements. These targets produce activity at multiple sites on a movement map in the superior colliculus (SC), an area of the brain related to saccade generation. The saccade made must result from competition between ...

journal_title：Journal of neurophysiology

authors： Port NL,Wurtz RH

更新日期：2003-09-01 00:00:00

abstract：:The aim of the study was to examine whether the sustained increases in the excitability of afferent fibers traversing the dorsal columns evoked by their polarization depend on the branching points of these fibers. To this end, the effects of epidural polarization were compared in four spinal regions in deeply anesthet...

journal_title：Journal of neurophysiology

authors： Li Y,Hari K,Lucas-Osma AM,Fenrich KK,Bennett DJ,Hammar I,Jankowska E

更新日期：2020-07-01 00:00:00

abstract：:We investigated spike-frequency adaptation of neurons sensitive to interaural phase disparities (IPDs) in the inferior colliculus (IC) of urethane-anesthetized guinea pigs using a stimulus paradigm designed to exclude the influence of adaptation below the level of binaural integration. The IPD-step stimulus consists o...

journal_title：Journal of neurophysiology

authors： Ingham NJ,McAlpine D

更新日期：2004-02-01 00:00:00

abstract：:Regional blood oxygenation in the cerebellum and posterior cerebral cortices was monitored with functional magnetic resonance imaging (fMRI) at four Tesla while 16 normal subjects performed three tasks with identical visual stimulation: fixation; attention focused upon either stimulus shape or color and sustained duri...

journal_title：Journal of neurophysiology

authors： Le TH,Pardo JV,Hu X

更新日期：1998-03-01 00:00:00