Dynamic control of irregular bursting in an identified neuron of an oscillatory circuit.

abstract：:The abundance of nitric oxide (NO) synthesizing enzymes identified in the vertebrate retina highlight the importance of NO as a signaling molecule in this tissue. Here we describe opposing actions of NO on the rod and cone photoreceptor synapse. Depolarization-induced increases of calcium concentration in rods and con...

journal_title：Journal of neurophysiology

authors： Kourennyi DE,Liu XD,Hart J,Mahmud F,Baldridge WH,Barnes S

更新日期：2004-07-01 00:00:00

abstract：:Interpretation of hemodynamic responses in epilepsy is hampered by an incomplete understanding of the underlying neurovascular coupling, especially the contributions of excitation and inhibition. We made simultaneous multimodal recordings of local field potentials (LFPs), firing of individual neurons, blood flow, and ...

journal_title：Journal of neurophysiology

authors： Saillet S,Quilichini PP,Ghestem A,Giusiano B,Ivanov AI,Hitziger S,Vanzetta I,Bernard C,Bénar CG

更新日期：2016-03-01 00:00:00

abstract：:We show that fast bimanual coordinative feedback responses can be reversed with changes in task goals. Participants moved a flexible virtual object across a finish line with an upward movement of both hands. In one condition, the middle of the object had to be aligned with a spatial goal at the end of the movement. In...

journal_title：Journal of neurophysiology

authors： Diedrichsen J,Gush S

更新日期：2009-01-01 00:00:00

abstract：:1. The lateral geniculate nucleus is the primary thalamic relay for the transfer of retinal signals to the visual cortex. Geniculate cells are heavily innervated from nonretinal sources, and these modify retinogeniculate transmission. A major ascending projection to the lateral geniculate nucleus arises from cholinerg...

journal_title：Journal of neurophysiology

authors： Uhlrich DJ,Tamamaki N,Murphy PC,Sherman SM

更新日期：1995-06-01 00:00:00

abstract：:1. In the intact cat eye, the responses of ganglion cells to light stimulation were recorded extracellularly and the actions of iontophoretically applied 2-amino-4-phosphonobutyrate (APB), a potent agonist at ON-bipolars, and of strychnine, a glycine antagonist, were investigated. 2. Under light-adapted conditions, th...

journal_title：Journal of neurophysiology

authors： Müller F,Wässle H,Voigt T

更新日期：1988-06-01 00:00:00

abstract：:Little is known about the substrates for the large-scale shifts in the cortical representation produced by limb amputation. Subcortical changes likely contribute to the cortical remodeling, yet there is little data regarding the extent and pattern of reorganization in thalamus after such a massive deafferentation. Mor...

journal_title：Journal of neurophysiology

authors： Florence SL,Hackett TA,Strata F

更新日期：2000-05-01 00:00:00

abstract：:1. In four human subjects, we measured the latency of saccadic eye movements made to a second, eccentric target after an initial, foveated target was extinguished. In separate interleaved trails, the targets were either both stationary ("fixation") or both moving with the same velocity ("pursuit"). For both fixation a...

journal_title：Journal of neurophysiology

authors： Krauzlis RJ,Miles FA

更新日期：1996-12-01 00:00:00

abstract：:Sensory adaptation serves to adjust awake brains to changing environments on different time scales. However, adaptation has been studied traditionally under anesthesia and for short time periods. Here, we demonstrate in awake rabbits a novel type of sensory adaptation that persists for >1 h and acts on visual thalamoc...

journal_title：Journal of neurophysiology

authors： Stoelzel CR,Huff JM,Bereshpolova Y,Zhuang J,Hei X,Alonso JM,Swadlow HA

更新日期：2015-08-01 00:00:00

abstract：:Functional magnetic resonance imaging (fMRI) is a noninvasive tool used to probe cognitive and affective processes. Although fMRI provides indirect measures of neural activity, the advent of fMRI has allowed for1) the corroboration of significant animal findings in the human brain, and2) the expansion of models to inc...

journal_title：Journal of neurophysiology

authors： Wang KS,Smith DV,Delgado MR

更新日期：2016-03-01 00:00:00

abstract：:The role of voltage-dependent calcium channels (VDCCs) in the nicotinic acetylcholine receptor (nAChR)-mediated enhancement of spontaneous GABAergic inhibitory postsynaptic currents (IPSCs) was investigated in chick brain slices. Whole cell recordings of neurons in the lateral spiriform (SpL) and ventral lateral genic...

journal_title：Journal of neurophysiology

authors： Tredway TL,Guo JZ,Chiappinelli VA

更新日期：1999-02-01 00:00:00

abstract：:Membrane-permeable arachidonic acid (AA) is liberated in a Ca2+-dependent way inside cells. By using whole cell patch clamp we show that intracellular AA (1 pM) selectively reduces IA in rat hippocampal neurons, whereas extracellular application requires a 10(6)-fold concentration. The nonmetabolized AA analogue ETYA ...

journal_title：Journal of neurophysiology

authors： Bittner K,Müller W

更新日期：1999-07-01 00:00:00

abstract：:Over the past 3 decades, various algorithms used to decompose the electromyographic (EMG) signal into its constituent motor unit action potentials (MUAPs) have been reported. All are limited to decomposing EMG signals from isometric contraction. In this report, we describe a successful approach to decomposing the surf...

journal_title：Journal of neurophysiology

authors： De Luca CJ,Chang SS,Roy SH,Kline JC,Nawab SH

更新日期：2015-03-15 00:00:00

abstract：:There is mounting evidence for the idea that performance in a visuomotor rotation task can be supported by both implicit and explicit forms of learning. The implicit component of learning has been well characterized in previous experiments and is thought to arise from the adaptation of an internal model driven by sens...

journal_title：Journal of neurophysiology

authors： Bond KM,Taylor JA

更新日期：2015-06-01 00:00:00

abstract：:Extracellular single-unit recordings were used to characterize responses of thalamic barreloid and cortical barrel neurons to controlled whisker deflections in 2, 3-, and 4-wk-old and adult rats in vivo under fentanyl analgesia. Results indicate that response properties of thalamic and cortical neurons diverge during ...

journal_title：Journal of neurophysiology

authors： Shoykhet M,Simons DJ

更新日期：2008-01-01 00:00:00

abstract：:Synaptic drugs were superfused into turtle eyecup preparation while recording extracellularly from directionally sensitive (DS) retinal ganglion cells. As in previous experiments in intact rabbit retina, both picrotoxin (a GABA antagonist) and physostigmine [an acetylcholine (ACh) potentiator] reduced or eliminated th...

journal_title：Journal of neurophysiology

authors： Ariel M,Adolph AR

更新日期：1985-11-01 00:00:00

abstract：:Experimental and clinical evidence indicates that pain can affect cognitive processes, but the cortical networks involved in pain-cognition interactions are unclear. In this study, we determined the effect of pain on the activity of cortical areas involved in cognition acting as a whole (i.e., a network). Subjects und...

journal_title：Journal of neurophysiology

authors： Seminowicz DA,Davis KD

更新日期：2007-05-01 00:00:00

abstract：:A tool or probe often functions as an extension of the hand, transmitting vibrations to the hand to produce a percept of the object contacting the tool or probe. This paper reports the psychophysical results of a combined psychophysical and neurophysiological study of the perception of vibration transmitted through a ...

journal_title：Journal of neurophysiology

authors： Brisben AJ,Hsiao SS,Johnson KO

更新日期：1999-04-01 00:00:00

abstract：:The cardiac ganglion (CG) of Homarus americanus is a central pattern generator that consists of two oscillatory groups of neurons: "small cells" (SCs) and "large cells" (LCs). We have shown that SCs and LCs begin their bursts nearly simultaneously but end their bursts at variable phases. This variability contrasts wit...

journal_title：Journal of neurophysiology

authors： Williams AH,Kwiatkowski MA,Mortimer AL,Marder E,Zeeman ML,Dickinson PS

更新日期：2013-05-01 00:00:00

abstract：:Frequent gait modifications are often required to navigate our world. These can involve long or wide steps or changes in direction. People generally prefer to minimize the motor cost (or effort) of a movement, although with changes in gait this is not always possible. The decision of when and where to shift gaze is cr...

journal_title：Journal of neurophysiology

authors： Domínguez-Zamora FJ,Marigold DS

更新日期：2019-07-01 00:00:00

abstract：:To elucidate how information is processed in the vestibuloocular reflex (VOR) pathways subserving vertical eye movements, extracellular single-unit recordings were obtained from the vestibular nuclei of alert monkeys trained to track a visual target with their eyes while undergoing sinusoidal pitch oscillations (0.2-1...

journal_title：Journal of neurophysiology

authors： Chubb MC,Fuchs AF,Scudder CA

更新日期：1984-10-01 00:00:00

abstract：:1. Spontaneous synaptic activity in networks formed by dissociated neurons from embryonic rat midbrain was analyzed in tight seal whole cell recordings. 2. Application of furosemide (0.5 mM) to the cell and its surrounding area increased the frequency of spontaneous synaptic currents. Incubation of the culture with fu...

journal_title：Journal of neurophysiology

authors： Jarolimek W,Brunner H,Lewen A,Misgeld U

更新日期：1996-06-01 00:00:00

abstract：:The contributions of the hyperpolarization-activated current, I(h), to generation of rhythmic activities are well described for various central neurons, particularly in thalamocortical circuits. In the present study, we investigated effects of a general anesthetic, propofol, on native I(h) in neurons of thalamus and c...

journal_title：Journal of neurophysiology

authors： Chen X,Shu S,Bayliss DA

更新日期：2005-12-01 00:00:00

abstract：:Recent evidence suggests that changes in sodium channel expression and localization may be involved in some pathological pain syndromes. SNS, a tetrodotoxin-resistant (TTX-R) sodium channel, is preferentially expressed in small dorsal root ganglion (DRG) neurons, many of which are nociceptive. TTX-R sodium currents an...

journal_title：Journal of neurophysiology

authors： Fjell J,Cummins TR,Fried K,Black JA,Waxman SG

更新日期：1999-02-01 00:00:00

abstract：:The execution of action sequences is the basis of most behavior. However, little is known about the neural foundation of visuomotor sequence execution in birds, although pigeons are a classic model animal to study sequence learning and production. Recently, we identified two structures in the pigeon brain, the nidopal...

journal_title：Journal of neurophysiology

authors： Helduser S,Cheng S,Güntürkün O

更新日期：2013-02-01 00:00:00

abstract：:Beyond being essential for long-term motor-skill development, movement repetition has immediate benefits on performance, increasing speed and accuracy of a second execution. While repetition effects have been reported for single reaching movements, it has yet to be determined whether they also occur for movement seque...

journal_title：Journal of neurophysiology

authors： Ariani G,Kwon YH,Diedrichsen J

更新日期：2020-05-01 00:00:00

abstract：:We have used electrophysiological techniques to document segmental differences in the pathways between the giant, escape command axons, lateral giants (LG) and medial giants (MG), and the nongiant, fast flexor (FF) motoneurons. We found no difference in the input from LG and MG axons to FF motoneurons in the posterior...

journal_title：Journal of neurophysiology

authors： Miller LA,Hagiwara G,Wine JJ

更新日期：1985-01-01 00:00:00

abstract：:A quantitative analysis of activity-related calcium dynamics was performed in motoneurons of the nucleus hypoglossus in the brain stem slice preparation from mouse by simultaneous patch-clamp and microfluorometric calcium measurements. Motoneurons were analyzed under in vitro conditions that kept them in a functionall...

journal_title：Journal of neurophysiology

authors： Lips MB,Keller BU

更新日期：1999-12-01 00:00:00

abstract：:Tinnitus and hyperacusis are common, burdensome sources of morbidity with a high rate of co-occurrence. Knudson et al. (J Neurophysiol 112: 3197-3208, 2014) demonstrated that efferent suppression of cochlear activity by the medial olivocochlear system is enhanced in individuals with tinnitus and/or hyperacusis. Their ...

journal_title：Journal of neurophysiology

authors： Sturm JJ,Weisz CJ

更新日期：2015-11-01 00:00:00

abstract：:Previous studies have reported that the translational vestibuloocular reflex (TVOR) follows a three-dimensional (3D) kinematic behavior that is more similar to visually guided eye movements, like pursuit, rather than the rotational VOR (RVOR). Accordingly, TVOR rotation axes tilted with eye position toward an eye-fixe...

journal_title：Journal of neurophysiology

authors： Angelaki DE

更新日期：2003-05-01 00:00:00

abstract：:Using whole cell patch-clamp recordings, we examined the effect of colchicine, a microtubule disrupter, on the properties of glycine receptors (GlyRs) in cultured spinal cord neurons. Confocal microscopy revealed that colchicine treatment effectively altered microtubule bundles and neuronal morphology. Application of ...

journal_title：Journal of neurophysiology

authors： van Zundert B,Alvarez FJ,Yevenes GE,Cárcamo JG,Vera JC,Aguayo LG

更新日期：2002-01-01 00:00:00