Abstract:
:Tinnitus and hyperacusis are common, burdensome sources of morbidity with a high rate of co-occurrence. Knudson et al. (J Neurophysiol 112: 3197-3208, 2014) demonstrated that efferent suppression of cochlear activity by the medial olivocochlear system is enhanced in individuals with tinnitus and/or hyperacusis. Their findings stress that atypical activity in the efferent auditory pathway may represent a shared substrate, as well as a potential therapeutic target, in tinnitus and hyperacusis.
journal_name
J Neurophysioljournal_title
Journal of neurophysiologyauthors
Sturm JJ,Weisz CJdoi
10.1152/jn.00948.2014subject
Has Abstractpub_date
2015-11-01 00:00:00pages
2551-4issue
5eissn
0022-3077issn
1522-1598pii
jn.00948.2014journal_volume
114pub_type
评论,杂志文章abstract::In humans, functional magnetic resonance imaging (fMRI) activity in the anterior cingulate cortex (ACC) and the nucleus accumbens (NAc) appears to reflect affective and motivational aspects of pain. The responses of this reward-aversion circuit to relief of pain, however, have not been investigated in detail. Moreover...
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