A cGMP-dependent protein kinase (PKG) controls synaptic transmission tolerance to acute oxidative stress at the Drosophila larval neuromuscular junction.

abstract：:Octopus cells in the posteroventral cochlear nucleus (PVCN) of mammals are biophysically specialized to detect coincident firing in the population of auditory nerve fibers that provide their synaptic input and to convey its occurrence with temporal precision. The precision in the timing of action potentials depends on...

journal_title：Journal of neurophysiology

authors： Bal R,Oertel D

更新日期：2001-11-01 00:00:00

abstract：:Motor behavior often occurs in environments with multiple goal options that can vary during the ongoing action. We explored this situation by requiring subjects to select between different target options during an ongoing reach. During split trials the original target was replaced with a left and a right flanking targ...

journal_title：Journal of neurophysiology

authors： Kurtzer IL,Muraoka T,Singh T,Prasad M,Chauhan R,Adhami E

更新日期：2020-10-01 00:00:00

abstract：:1. The effects of dopamine on the slow Ca(2+)-dependent K+ current (IAHP; AHP, afterhyperpolarization) and spike frequency adaptation were studied by whole cell voltage-clamp and sharp microelectrode current-clamp recordings in rat CA1 pyramidal neurons in rat hippocampal slices. 2. Dopamine suppressed IAHP in a dose-...

journal_title：Journal of neurophysiology

authors： Pedarzani P,Storm JF

更新日期：1995-12-01 00:00:00

abstract：:PSD-95-like, disc-large (DLG) family membrane-associated guanylate kinase proteins (PSD/DLG-MAGUKs) are essential for regulating synaptic AMPA receptor (AMPAR) function and activity-dependent trafficking of AMPARs. Using a molecular replacement strategy to replace endogenous PSD-95 with SAP97β, we show that the protot...

journal_title：Journal of neurophysiology

authors： Liu M,Lewis LD,Shi R,Brown EN,Xu W

更新日期：2014-02-01 00:00:00

abstract：:Most retinal bipolar cells (BCs) transmit visual input from photoreceptors to ganglion cells using graded potentials, but some also generate calcium or sodium spikes. Sodium spikes are thought to increase temporal precision of light-evoked BC signaling; however, the role of calcium spikes in BCs is not fully understoo...

journal_title：Journal of neurophysiology

authors： Lipin MY,Vigh J

更新日期：2015-01-15 00:00:00

abstract：:1. The sensorimotor synapse of Aplysia expresses various shortlasting changes in synaptic efficacy including homosynaptic depression (HSD) and heterosynaptic facilitation by serotonin (5-HT) either at nondepressed sensory neuron (SN) synaptic connections or at SN synaptic connections first depressed by HSD. We examine...

journal_title：Journal of neurophysiology

authors： Sun ZY,Schacher S

更新日期：1996-10-01 00:00:00

abstract：:The mechanism(s) of olfactory transduction in invertebrates remains to be fully understood. In lobster olfactory receptor neurons (ORNs), a nonselective sodium-gated cation (SGC) channel, a presumptive transient receptor potential (TRP)C channel homolog, plays a crucial role in olfactory transduction, at least in part...

journal_title：Journal of neurophysiology

authors： Pezier A,Bobkov YV,Ache BW

更新日期：2009-03-01 00:00:00

abstract：:The cerebral cortex, the neostriatum (Str), and the external segment of the globus pallidus (GPe) form a cortico-Str-GPe disynaptic connection, which is one of the major connections in the basal ganglia circuitries and a target of dopamine modulation. The aim of this study was to examine the actions of D2-like dopamin...

journal_title：Journal of neurophysiology

authors： Watanabe K,Kita T,Kita H

更新日期：2009-02-01 00:00:00

abstract：:Adult rats were submitted to a complete spinal cord transection at T9 level to address peripheral and spinal reflex changes in the caudal lumbar segments. Compound muscle and nerve action potentials decreased in amplitude and increased their duration between 14 and 30 days but recovered to near to normal values therea...

journal_title：Journal of neurophysiology

authors： Valero-Cabré A,Forés J,Navarro X

更新日期：2004-06-01 00:00:00

abstract：:The present paper investigates the sensory-driven modulations of central pattern generator dynamics that can be expected to reproduce human behavior during rhythmic hybrid tasks. We propose a theoretical model of human sensorimotor behavior able to account for the observed data from the ball-bouncing task. The novel c...

journal_title：Journal of neurophysiology

authors： Avrin G,Siegler IA,Makarov M,Rodriguez-Ayerbe P

更新日期：2017-10-01 00:00:00

abstract：:The exercise pressor reflex (EPR) is generated by group III and IV muscle afferents during exercise to increase cardiovascular function. Muscle contraction is triggered by ACh, which is metabolized into choline that could serve as a signal of exercise-induced activity. We demonstrate that ACh can induce current in mus...

journal_title：Journal of neurophysiology

authors： Baxter JC,Ramachandra R,Mayne DR,Elmslie KS

更新日期：2014-09-15 00:00:00

abstract：:A preparation is described in which the thoracic ganglia of the crayfish are isolated together with the thoracocoxal muscle receptor organ (TCMRO) of the fourth leg. This preparation allows intracellular analysis of both centrally generated and reflex activity in leg motor neurons (MNs). The isolated thoracic ganglia ...

journal_title：Journal of neurophysiology

authors： Sillar KT,Skorupski P

更新日期：1986-04-01 00:00:00

abstract：:1. We recorded from 257 neurons in the banks of the posterior third of the principal sulcus of two rhesus monkeys trained to look at a fixation point and make saccades to stimuli in the visual periphery. Sixty-six percent (220/257) discharged or were suppressed in association with one or more aspects of the tasks we u...

journal_title：Journal of neurophysiology

authors： Boch RA,Goldberg ME

更新日期：1989-05-01 00:00:00

abstract：:Intracellular recording from lumbar motoneurons and extracellular recording from ventral roots of the neonatal rat isolated spinal cord were used to study the mechanisms responsible for the excitation mediated by NK3 tachykinin receptors. The selective NK3 agonists senktide or [MePhe7]neurokinin B induced a slow depol...

journal_title：Journal of neurophysiology

authors： Marchetti C,Nistri A

更新日期：2001-12-01 00:00:00

abstract：:Cacna1a encodes the pore-forming α1A subunit of CaV2.1 voltage-dependent calcium channels, which regulate neuronal excitability and synaptic transmission. Purkinje cells in the cortex of cerebellum abundantly express these CaV2.1 channels. Here, we show that homozygous tottering (tg) mice, which carry a loss-of-functi...

journal_title：Journal of neurophysiology

authors： de Oude NL,Hoebeek FE,Ten Brinke MM,de Zeeuw CI,Boele HJ

更新日期：2020-12-16 00:00:00

abstract：:Amino acid and bile salt odorants are detected by zebrafish with relatively independent odorant receptors, but the transduction cascade(s) subsequently activated by these odorants remains unknown. Electro-olfactogram recording methods were used to determine the effects of two drugs, reported to affect phospholipase C ...

journal_title：Journal of neurophysiology

authors： Ma L,Michel WC

更新日期：1998-03-01 00:00:00

abstract：:1. Whole cell patch-clamp recordings were made of low-voltage-activated (LVA) calcium (Ca2+) currents using 2 mM barium (Ba2+) as charge carrier. Acutely dissociated neurons from medial septum (MS) and the nucleus of the diagonal band (nDB) were examined in young adult (1-3 mo) and aged (24-26 mo) Fischer 344 rats. 2....

journal_title：Journal of neurophysiology

authors： Murchison D,Griffith WH

更新日期：1995-08-01 00:00:00

abstract：:1. The hyperpolarization that follows tetanic stimulation was recorded intra-axonally from the internodal region of intramuscular myelinated motor axons. 2. The peak amplitude of the posttetanic hyperpolarization (PTH) that followed stimulation at 20-100 Hz for < or = 35 s increased with increasing train duration, rea...

journal_title：Journal of neurophysiology

authors： Morita K,David G,Barrett JN,Barrett EF

更新日期：1993-11-01 00:00:00

abstract：:The nucleus gracilis (NG) receives an abundance of visceral input from various abdominal organs and is proposed to play an important role in visceral pain processing. The purpose of this study was to investigate the necessity of the NG for colorectal input into the ventral posterolateral (VPL) nucleus of the thalamus....

journal_title：Journal of neurophysiology

authors： Al-Chaer ED,Westlund KN,Willis WD

更新日期：1997-07-01 00:00:00

abstract：:We examined the activity of neurons in the lateral intraparietal area (LIP) during a task in which we measured attention in the monkey, using an advantage in contrast sensitivity as our definition of attention. The animals planned a memory-guided saccade but made or canceled it depending on the orientation of a briefl...

journal_title：Journal of neurophysiology

authors： Bisley JW,Goldberg ME

更新日期：2006-03-01 00:00:00

abstract：:Attention is known to affect the response properties of sensory neurons in visual cortex. These effects have been traditionally classified into two categories: 1) changes in the gain (overall amplitude) of the response; and 2) changes in the tuning (selectivity) of the response. We performed an extensive series of beh...

journal_title：Journal of neurophysiology

authors： Paltoglou AE,Neri P

更新日期：2012-03-01 00:00:00

abstract：:1. The question of whether active uptake limits the duration of action of the inhibitory transmitter glycine has been addressed in vivo at inhibitory synapses on the goldfish Mauthner (M) cell. The kinetics of inhibitory postsynaptic potentials and inhibitory postsynaptic currents (IPSCs) evoked antidromically and by ...

journal_title：Journal of neurophysiology

authors： Titmus MJ,Korn H,Faber DS

更新日期：1996-04-01 00:00:00

abstract：:The cerebellum was historically considered a brain region dedicated to motor control, but it has become clear that it also contributes to sensory processing, particularly when sensory discrimination is required. Prior work, for example, has demonstrated a cerebellar contribution to sensory discrimination in the visual...

journal_title：Journal of neurophysiology

authors： Dahlem K,Valko Y,Schmahmann JD,Lewis RF

更新日期：2016-05-01 00:00:00

abstract：:An initial overload of intracellular Ca2+ plays a critical role in the delayed death of hippocampal CA1 neurons that die a few days after transient ischemia. Without direct evidence, the prevailing hypothesis has been that Ca2+ overload may recur until cell death. Here, we report the first measurements of intracellula...

journal_title：Journal of neurophysiology

authors： Connor JA,Razani-Boroujerdi S,Greenwood AC,Cormier RJ,Petrozzino JJ,Lin RC

更新日期：1999-01-01 00:00:00

abstract：:In the mammalian vestibular periphery, electrical activation of the efferent vestibular system (EVS) has two effects on afferent activity: 1) it increases background afferent discharge and 2) decreases afferent sensitivity to rotational stimuli. Although the cellular mechanisms underlying these two contrasting afferen...

journal_title：Journal of neurophysiology

authors： Poppi LA,Tabatabaee H,Drury HR,Jobling P,Callister RJ,Migliaccio AA,Jordan PM,Holt JC,Rabbitt RD,Lim R,Brichta AM

更新日期：2018-01-01 00:00:00

abstract：:Responses have been recorded from primary endings of muscle spindles in the cat soleus muscle. Changes in spindle responsiveness were measured following a period of conditioning that consisted of a series of rapid stretches or of tetanic ventral root stimulation. In the testing procedure the response of a single spind...

journal_title：Journal of neurophysiology

authors： Gregory JE,Morgan DL,Proske U

更新日期：1986-08-01 00:00:00

abstract：:Changes in temperature of up to several degrees have been reported in different brain regions during various behaviors or in response to environmental stimuli. We investigated temperature sensitivity of dopaminergic neurons of the rat substantia nigra pars compacta (SNc), an area important for motor and emotional cont...

journal_title：Journal of neurophysiology

authors： Guatteo E,Chung KK,Bowala TK,Bernardi G,Mercuri NB,Lipski J

更新日期：2005-11-01 00:00:00

abstract：:Exposure to odorants results in a rapid (<10 s) reduction in odor-evoked activity in the rat piriform cortex despite relatively maintained afferent input from olfactory bulb mitral cells. To further understand this form of cortical plasticity, a detailed analysis of its odor specificity was performed. Habituation of o...

journal_title：Journal of neurophysiology

authors： Wilson DA

更新日期：2000-01-01 00:00:00

abstract：:Sex-specific behaviors of some vertebrates are reversible by androgen administered in adulthood. Such behavioral transformations in adulthood provide opportunities to identify how neural systems reconfigure to produce sex-specific behavior. In this study, we focused on the vocalizations of the African clawed frog, Xen...

journal_title：Journal of neurophysiology

authors： Potter KA,Bose T,Yamaguchi A

更新日期：2005-07-01 00:00:00

abstract：:1. The stiffness during the initial portion of a ramp stretch was measured in cat peroneus longus muscle at rest and during maximal tetanic contractions produced by increasing numbers of motor units of the same type [slow (S), fast fatigue resistant (FR), or fast fatigable (FF)]. 2. This initial ramp stiffness was def...

journal_title：Journal of neurophysiology

authors： Petit J,Filippi GM,Gioux M,Hunt CC,Laporte Y

更新日期：1990-12-01 00:00:00