Dopamine modulates the slow Ca(2+)-activated K+ current IAHP via cyclic AMP-dependent protein kinase in hippocampal neurons.

abstract：:We have investigated whether neurons in superficial laminae of the spinal dorsal horn respond to intracutaneous (ic) delivery of histamine and other irritant chemicals, and thus might be involved in signaling sensations of itch or chemogenic pain. Single-unit recordings were made from superficial lumbar dorsal horn ne...

journal_title：Journal of neurophysiology

authors： Jinks SL,Carstens E

更新日期：2000-08-01 00:00:00

abstract：:PSD-95-like, disc-large (DLG) family membrane-associated guanylate kinase proteins (PSD/DLG-MAGUKs) are essential for regulating synaptic AMPA receptor (AMPAR) function and activity-dependent trafficking of AMPARs. Using a molecular replacement strategy to replace endogenous PSD-95 with SAP97β, we show that the protot...

journal_title：Journal of neurophysiology

authors： Liu M,Lewis LD,Shi R,Brown EN,Xu W

更新日期：2014-02-01 00:00:00

abstract：:GABA(B)-receptor-mediated inhibition was investigated in anatomically identified inhibitory interneurons located at the border between the dentate gyrus granule cell layer and hilus. Biocytin staining was used to visualize the morphology of recorded cells. A molecular layer stimulus evoked a pharmacologically isolated...

journal_title：Journal of neurophysiology

authors： Mott DD,Li Q,Okazaki MM,Turner DA,Lewis DV

更新日期：1999-09-01 00:00:00

abstract：:Many single-unit electrophysiological studies of visual cortex have investigated strong evoked responses to simple stimuli such as oriented gratings. Experiments involving other types of stimuli, such as natural scenes, higher-order features, and surface brightness, produce single-unit responses that are more difficul...

journal_title：Journal of neurophysiology

authors： Hung CP,Ramsden BM,Roe AW

更新日期：2002-05-01 00:00:00

abstract：:Inhibition is presumed to play an important role in gustatory processing in the rostral nucleus of the solitary tract (rNST). One source of inhibition, GABA, is abundant within the nucleus and comes both from local, intrasolitary sources and from outside the nucleus. In addition to the receptor-mediated effects of GAB...

journal_title：Journal of neurophysiology

authors： Chen Z,Travers SP,Travers JB

更新日期：2016-08-01 00:00:00

abstract：:Ankle inversions have been studied extensively during standing conditions. However, inversion traumas occur during more dynamic conditions, like walking. Therefore in this study sudden ankle inversions were elicited in 12 healthy subjects who stepped on a trap door while walking on a treadmill. First, 10 control trial...

journal_title：Journal of neurophysiology

authors： Nieuwenhuijzen PH,Duysens J

更新日期：2007-10-01 00:00:00

abstract：:1. In a previous study, using a chronic cat preparation subjected to an associative conditioning procedure, we described the plasticity of the thalamo-cortical pathway by qualitatively and quantitatively analyzing the motor responses induced by stimulating each of the relays on the cerebello-thalamo-cortical pathway. ...

journal_title：Journal of neurophysiology

authors： Meftah EM,Rispal-Padel L

更新日期：1994-12-01 00:00:00

abstract：:A spherical approximation technique is presented that affords a mathematical characterization of a virtual space receptive field (VSRF) based on first-spike latency in the auditory cortex of cat. Parameterizing directional sensitivity in this fashion is much akin to the use of difference-of-Gaussian (DOG) functions fo...

journal_title：Journal of neurophysiology

authors： Jenison RL,Reale RA,Hind JE,Brugge JF

更新日期：1998-11-01 00:00:00

abstract：:We explored how contour information in primary visual cortex might be embedded in the simultaneous activity of multiple cells recorded with a 100-electrode array. Synchronous activity in cat visual cortex was more selective and predictable in discriminating between drifting grating and concentric ring stimuli than cha...

journal_title：Journal of neurophysiology

authors： Samonds JM,Zhou Z,Bernard MR,Bonds AB

更新日期：2006-04-01 00:00:00

abstract：:The synaptic plasticity literature has focused on establishing necessity and sufficiency as two essential and distinct features in causally relating a signaling molecule to plasticity induction, an approach that has been surprisingly lacking in the intrinsic plasticity literature. In this study, we complemented the re...

journal_title：Journal of neurophysiology

authors： Ashhad S,Johnston D,Narayanan R

更新日期：2015-04-01 00:00:00

abstract：:1. The properties of parietal neurons were studied in four adult rhesus monkeys during fast arm movements. The animals were trained to perform flexion or extension of the forearm about the elbow in response to specific auditory cues. Single neuron activity was recorded in 272 area 5 neurons, 81 neurons of the somatose...

journal_title：Journal of neurophysiology

authors： Burbaud P,Doegle C,Gross C,Bioulac B

更新日期：1991-08-01 00:00:00

abstract：:In many central pattern generators, pairs of neurons maintain an approximately fixed phase despite large changes in the frequency. The mechanisms underlying phase maintenance are not clear. Previous theoretical work suggested that inhibitory synapses that show short-term depression could play a critical role in this r...

journal_title：Journal of neurophysiology

authors： Greenberg I,Manor Y

更新日期：2005-02-01 00:00:00

abstract：:In this study, the juxtamembrane region of the Drosophila SNARE protein neuronal-Synaptobrevin (n-Syb) was tested for its role in synaptic transmission. A transgenic approach was used to express n-Syb mutant genes. The transgenes carried engineered point mutations that alter the amino acid sequence of the conserved tr...

journal_title：Journal of neurophysiology

authors： DeMill CM,Qiu X,Kisiel M,Bolotta A,Stewart BA

更新日期：2014-09-15 00:00:00

abstract：:Working memory (WM) for sensory-based information about individual objects and their locations appears to involve interactions between lateral prefrontal and sensory cortexes. The mechanisms and representations for maintenance of more abstract, nonsensory information in WM are unknown, particularly whether such active...

journal_title：Journal of neurophysiology

authors： Ikkai A,Blacker KJ,Lakshmanan BM,Ewen JB,Courtney SM

更新日期：2014-10-15 00:00:00

abstract：:Recent evidence has suggested that theta-frequency (4-7 Hz) oscillations around the human anterior cingulate cortex (ACC) and frontal cortex--that is, frontal midline theta (Fm theta) oscillations--may be involved in attentional processes in the brain. However, little is known about the physiological basis of Fm theta...

journal_title：Journal of neurophysiology

authors： Tsujimoto T,Shimazu H,Isomura Y

更新日期：2006-05-01 00:00:00

abstract：:Dual whole-cell patch clamp recordings from the soma and dendrites of CA1 pyramidal neurons located in hippocampal slices of adult rats were used to examine the potential mechanisms of phase precession. To mimic phasic synaptic input, 5-Hz sine wave current injections were simultaneously delivered both to the soma and...

journal_title：Journal of neurophysiology

authors： Magee JC

更新日期：2001-07-01 00:00:00

abstract：:Reward and punishment have opposite affective value but are both processed by the cingulate cortex. However, it is unclear whether the positive and negative affective values of monetary reward and punishment are processed by separate or common subregions of the cingulate cortex. We performed a functional magnetic reso...

journal_title：Journal of neurophysiology

authors： Fujiwara J,Tobler PN,Taira M,Iijima T,Tsutsui K

更新日期：2009-06-01 00:00:00

abstract：:Anatomical and physiological data have implicated the pretectal olivary nucleus (PON) as the midbrain relay for the pupillary light reflex in a variety of species. To determine the nature of the discharge of pretectal light reflex relay neurons, we recorded their activity in monkeys that were fixating a stationary spo...

journal_title：Journal of neurophysiology

authors： Pong M,Fuchs AF

更新日期：2000-08-01 00:00:00

abstract：:1. Behavioral studies in the monkey and clinical studies in humans show that some visuomotor functions are spared in case of a V1 lesion. This residual vision appears to be subserved at least partially by visual activity in extrastriate cortex. Earlier studies have demonstrated that neurons in area V2 lose their visua...

journal_title：Journal of neurophysiology

authors： Girard P,Salin PA,Bullier J

更新日期：1991-11-01 00:00:00

abstract：:Ablation and single-unit studies in primates have shown that inferior temporal (IT) cortex is important for pattern discrimination. The first paper in this series suggested that single units in IT cortex of alert monkeys respond to a set of two-dimensional patterns with complex temporal modulation of their spike train...

journal_title：Journal of neurophysiology

authors： Optican LM,Richmond BJ

更新日期：1987-01-01 00:00:00

abstract：:Ocular following (OFR) is a short-latency visual stabilization response to the optic flow experienced during self-motion. It has been proposed that it represents the early component of optokinetic nystagmus (OKN) and that it is functionally linked to the vestibularly driven stabilization reflex during translation (tra...

journal_title：Journal of neurophysiology

authors： Adeyemo B,Angelaki DE

更新日期：2005-03-01 00:00:00

abstract：:Experimental and clinical evidence indicates that pain can affect cognitive processes, but the cortical networks involved in pain-cognition interactions are unclear. In this study, we determined the effect of pain on the activity of cortical areas involved in cognition acting as a whole (i.e., a network). Subjects und...

journal_title：Journal of neurophysiology

authors： Seminowicz DA,Davis KD

更新日期：2007-05-01 00:00:00

abstract：:The last few years have seen an increase in the variety of in vivo experiments used for studying cerebellar physiological mechanisms. A combination of ketamine and xylazine has become a particularly popular form of anesthesia. However, because nonanesthetized control conditions are lacking in these experiments, so far...

journal_title：Journal of neurophysiology

authors： Bengtsson F,Jörntell H

更新日期：2007-09-01 00:00:00

abstract：:1. Effects of substance P (SP) and other tachykinins on membrane currents were investigated using whole cell voltage clamp in cultured sensory neurons isolated from rat dorsal root ganglia. 2. SP (100 nM) evoked an inward current in two-thirds of the cells at negative potentials. In most of the cells that generated th...

journal_title：Journal of neurophysiology

authors： Inoue K,Nakazawa K,Inoue K,Fujimori K

更新日期：1995-02-01 00:00:00

abstract：:Single pulses of transcranial magnetic stimulation (TMS) result in distal and long-lasting oscillations, a finding directly challenging the virtual lesion hypothesis. Previous research supporting this finding has primarily come from stimulation of the motor cortex. We have used single-pulse TMS with simultaneous EEG t...

journal_title：Journal of neurophysiology

authors： Garcia JO,Grossman ED,Srinivasan R

更新日期：2011-10-01 00:00:00

abstract：:The potassium-chloride cotransporter 2 (KCC2) plays a role in epileptiform synchronization, but it remains unclear how it influences such a process. Here, we used tetrode recordings in the in vitro rat entorhinal cortex (EC) to analyze the effects of the KCC2 antagonist VU0463271 on 4-aminopyridine (4AP)-induced ictal...

journal_title：Journal of neurophysiology

authors： Chen LY,Lévesque M,Avoli M

更新日期：2019-09-01 00:00:00

abstract：:Sex-specific behaviors of some vertebrates are reversible by androgen administered in adulthood. Such behavioral transformations in adulthood provide opportunities to identify how neural systems reconfigure to produce sex-specific behavior. In this study, we focused on the vocalizations of the African clawed frog, Xen...

journal_title：Journal of neurophysiology

authors： Potter KA,Bose T,Yamaguchi A

更新日期：2005-07-01 00:00:00

abstract：:1. The functional organization of interneurons in spinal laminae III-V was studied in an isolated preparation of hamster dorsal horn with sensory innervation from an excised skin patch. Morphological details of 40 neurons were visualized by intracellular injection of horseradish peroxidase. Active and passive membrane...

journal_title：Journal of neurophysiology

authors： Schneider SP

更新日期：1992-11-01 00:00:00

abstract：:The neuronal mechanism which gives rise to the synchronization of motor-unit discharges has been inferred from an analysis of the interspike intervals of individual motor-unit discharges recorded from the soleus muscle. The motor units were divided into two groups on the basis of characteristic changes in their spike ...

journal_title：Journal of neurophysiology

authors： Mori S

更新日期：1975-07-01 00:00:00

abstract：:Cacna1a encodes the pore-forming α1A subunit of CaV2.1 voltage-dependent calcium channels, which regulate neuronal excitability and synaptic transmission. Purkinje cells in the cortex of cerebellum abundantly express these CaV2.1 channels. Here, we show that homozygous tottering (tg) mice, which carry a loss-of-functi...

journal_title：Journal of neurophysiology

authors： de Oude NL,Hoebeek FE,Ten Brinke MM,de Zeeuw CI,Boele HJ

更新日期：2020-12-16 00:00:00