Activation of InsP₃ receptors is sufficient for inducing graded intrinsic plasticity in rat hippocampal pyramidal neurons.

abstract：:Sensory adaptation serves to adjust awake brains to changing environments on different time scales. However, adaptation has been studied traditionally under anesthesia and for short time periods. Here, we demonstrate in awake rabbits a novel type of sensory adaptation that persists for >1 h and acts on visual thalamoc...

journal_title：Journal of neurophysiology

authors： Stoelzel CR,Huff JM,Bereshpolova Y,Zhuang J,Hei X,Alonso JM,Swadlow HA

更新日期：2015-08-01 00:00:00

abstract：:1. Voltage-dependent Na+ conductances were studied in small (18-25 microns diam) adult rat dorsal root ganglion (DRG) neurons with the use of the whole cell patch-clamp technique. Na+ currents were also recorded from larger (44-50 microns diam) neurons and compared with those of the small neurons. 2. The predominant N...

journal_title：Journal of neurophysiology

authors： Rizzo MA,Kocsis JD,Waxman SG

更新日期：1994-12-01 00:00:00

abstract：:Ipsilaterally projecting spinal excitatory interneurons (EINs) generate the hemisegmental rhythmic locomotor activity in lamprey, while the commissural interneurons ensure proper left-right alternation. 5-HT is a potent modulator of the locomotor rhythm and is endogenously released from the spinal cord during fictive ...

journal_title：Journal of neurophysiology

authors： Biró Z,Hill RH,Grillner S

更新日期：2006-08-01 00:00:00

abstract：:1. The effects of the di- and trivalent trace metal cations, Pb2+, Zn2+, and Al3+, on voltage-activated calcium channel currents recorded from cultured rat dorsal root ganglion neurons were determined. 2. All three cations blocked transient and sustained components of the voltage-gated calcium channel currents elicite...

journal_title：Journal of neurophysiology

authors： Büsselberg D,Platt B,Michael D,Carpenter DO,Haas HL

更新日期：1994-04-01 00:00:00

abstract：:1. Membrane currents of normal and TEA-injected cat lumbar motoneurons were investigated using the technique of somatic voltage clamp. 2. The current-voltage (I-V) relation of healthy motoneurons contains a region of negative slope conductance caused by a persistent inward current component (Ii). In the most striking ...

journal_title：Journal of neurophysiology

authors： Schwindt PC,Crill WE

更新日期：1980-06-01 00:00:00

abstract：:The role of metabotropic glutamate receptors (mGluRs) and adenosine receptors in hypoxia-induced suppression of excitatory synaptic input to interneurons residing at the granule cell-hilus border in the dentate gyrus was investigated with the use of whole cell electrophysiological recording techniques in thin (250 mic...

journal_title：Journal of neurophysiology

authors： Doherty J,Dingledine R

更新日期：1997-01-01 00:00:00

abstract：:Whenever the eyes move, spatial attention must keep track of the locations of targets as they shift on the retina. This study investigated transsaccadic updating of visual attention to cued targets. While observers prepared a saccade, we flashed an irrelevant, but salient, color cue in their visual periphery and measu...

journal_title：Journal of neurophysiology

authors： Jonikaitis D,Szinte M,Rolfs M,Cavanagh P

更新日期：2013-03-01 00:00:00

abstract：:The present study was undertaken to explore the neuronal mechanisms responsible for muscle atonia that occurs after the microinjection of bicuculline into the nucleus pontis oralis (NPO). Specifically, we wished to test the hypothesis that motoneurons are postsynaptically inhibited after the microinjection of bicucull...

journal_title：Journal of neurophysiology

authors： Xi MC,Morales FR,Chase MH

更新日期：2001-10-01 00:00:00

abstract：:1. Pulse inputs (similar to tendon jerks) were applied to the human ankle joint with the use of a hydraulic actuator. Inputs of only 1-2 degrees could elicit large responses (> 20% of maximum voluntary contraction). The magnitude of the response depended nonlinearly on a number of factors: the amplitude, direction, an...

journal_title：Journal of neurophysiology

authors： Stein RB,Kearney RE

更新日期：1995-01-01 00:00:00

abstract：:Motor networks such as the pyloric network of the stomatogastric ganglion often require descending neuromodulatory inputs to initiate, regulate, and modulate their activity and their synaptic connectivity to manifest physiologically appropriate output. Prolonged removal of these descending inputs often results in a co...

journal_title：Journal of neurophysiology

authors： Nahar J,Lett KM,Schulz DJ

更新日期：2012-08-01 00:00:00

abstract：:According to Alexander's law (AL), the slow phase velocity of nystagmus of vestibular origin is dependent on horizontal position, with lower velocity when gaze is directed in the slow compared with the fast phase direction. Adaptive changes in the velocity-to-position neural integrator are thought to cause AL. Althoug...

journal_title：Journal of neurophysiology

authors： Bockisch CJ,Hegemann S

更新日期：2008-12-01 00:00:00

abstract：:The hypocretin/orexins (Hcrt/Orxs) are hypothalamic neuropeptides that regulate stress, addiction, feeding, and arousal behaviors. They depolarize many types of central neurons and can increase [Ca2+]i in some, including those of the dorsal raphe (DR) and laterodorsal tegmental (LDT) nuclei-two structures likely to co...

journal_title：Journal of neurophysiology

authors： Kohlmeier KA,Watanabe S,Tyler CJ,Burlet S,Leonard CS

更新日期：2008-10-01 00:00:00

abstract：:Recent studies conducted in our laboratory have suggested that the tongue primary motor cortex (i.e., tongue-MI) plays a critical role in the control of voluntary tongue movements in the primate. However, the possible involvement of tongue-MI in semiautomatic tongue movements, such as those in swallowing, remains unkn...

journal_title：Journal of neurophysiology

authors： Martin RE,Murray GM,Kemppainen P,Masuda Y,Sessle BJ

更新日期：1997-09-01 00:00:00

abstract：:As a vital skill in an evolving world, interception of moving objects relies on accurate prediction of target motion. In natural circumstances, active gaze shifts often accompany hand movements when exploring targets of interest, but how eye and hand movements are coordinated during manual interception and their depen...

journal_title：Journal of neurophysiology

authors： Li Y,Wang Y,Cui H

更新日期：2018-01-01 00:00:00

abstract：:At many glutamatergic synapses, non-N-methyl-d-aspartate (NMDA) and NMDA receptors are coexpressed postsynaptically. In the mammalian retina, glutamatergic rod bipolar cells are presynaptic to two rod amacrine cells (AII and A17) that constitute dyad postsynaptic partners opposite each presynaptic active zone. Whereas...

journal_title：Journal of neurophysiology

authors： Zhou Y,Tencerová B,Hartveit E,Veruki ML

更新日期：2016-01-01 00:00:00

abstract：:In the preceding report, we observed that tail-shock-induced sensitization of tail-elicited siphon withdrawal reflex (TSW) of Aplysia was expressed ipsilaterally but that dishabituation induced by an identical tail shock was expressed bilaterally. Here we examined the mechanisms of this differential lateralization. We...

journal_title：Journal of neurophysiology

authors： Bristol AS,Marinesco S,Carew TJ

更新日期：2004-02-01 00:00:00

abstract：:Using near-infrared spectroscopy (NIRS) and multichannel probes, we studied hemoglobin (Hb) concentration changes when single-pulse transcranial magnetic stimulation (TMS) was applied over the left hemisphere primary motor cortex (M1). Seventeen measurement probes were centered over left M1. Subjects were studied in b...

journal_title：Journal of neurophysiology

authors： Furubayashi T,Mochizuki H,Terao Y,Arai N,Hanajima R,Hamada M,Matsumoto H,Nakatani-Enomoto S,Okabe S,Yugeta A,Inomata-Terada S,Ugawa Y

更新日期：2013-03-01 00:00:00

abstract：:Neuromuscular synapses in buccal muscle I3a of Aplysia are modulated by the small cardioactive peptide (SCP), a peptide cotransmitter that is intrinsic to the motor neurons, and by serotonin (5-HT) released from modulatory neurons that are extrinsic to the motor circuit. Although the modulation of excitatory junction ...

journal_title：Journal of neurophysiology

authors： Fox LE,Lloyd PE

更新日期：2000-03-01 00:00:00

abstract：:Previous research using a loud acoustic stimulus (LAS) to investigate motor preparation in reaction time (RT) tasks indicates that responses can be triggered well in advance of the presentation of an imperative stimulus (IS). This is intriguing given that high levels of response preparation cannot be maintained for lo...

journal_title：Journal of neurophysiology

authors： Marinovic W,de Rugy A,Lipp OV,Tresilian JR

更新日期：2013-02-01 00:00:00

abstract：:Neurons integrate subthreshold inputs in a frequency-dependent manner. For sinusoidal stimuli, response amplitudes thus vary with stimulus frequency. Neurons in entorhinal cortex show two types of such resonance behavior: stellate cells in layer II exhibit a prominent peak in the resonance profile at stimulus frequenc...

journal_title：Journal of neurophysiology

authors： Schreiber S,Erchova I,Heinemann U,Herz AV

更新日期：2004-07-01 00:00:00

abstract：:Glass micropipettes were used to record the activity of 124 single units in the somatosensory vibrissa cortex (SI) of 16 rats in response to combined deflections of contralateral vibrissae. Compact multiangular electromechanical stimulators were used to stimulate individual vibrissal hairs alone or in combinations of ...

journal_title：Journal of neurophysiology

authors： Simons DJ

更新日期：1985-09-01 00:00:00

abstract：:1. Firing of cerebral neuron, C-PR, produced complex bilateral movements of various regions of the body of the marine mollusc Aplysia californica. The movements were similar to those seen when the animal assumes the head-up feeding posture during food-induced arousal. Muscles of the neck largely contracted in transver...

journal_title：Journal of neurophysiology

authors： Nagahama T,Weiss KR,Kupfermann I

更新日期：1993-09-01 00:00:00

abstract：:During early development neuronal networks express slow oscillating synchronized activity. The activity can be driven by several, not necessarily mutually exclusive, mechanisms. Each mechanism might have distinctive consequences for the phenomenology, formation, or sustainment of the early activity pattern. Here we st...

journal_title：Journal of neurophysiology

authors： Baltz T,Herzog A,Voigt T

更新日期：2011-09-01 00:00:00

abstract：:The lateral hypothalamus (LH), which plays a role in homeostatic functions such as appetite regulation, is also linked to arousal and motivational behavior. However, little is known about how these components are encoded in the LH. Thus cynomolgus monkeys were conditioned with two distinct contexts, i.e., an appetitiv...

journal_title：Journal of neurophysiology

authors： Noritake A,Nakamura K

更新日期：2019-02-01 00:00:00

abstract：:1. We have previously shown that Xenopus spinal motoneurons make both chemical and electrical synapses with neighboring motoneurons. Because motoneurons are active during swimming, these synapses would be expected to contribute excitation to their neighbors. The significance of central motoneuron to motoneuron synapse...

journal_title：Journal of neurophysiology

authors： Perrins R,Roberts A

更新日期：1995-03-01 00:00:00

abstract：:The uppermost layer (stratum griseum superficiale, SGS) of the superior colliculus (SC) provides an important gateway from the retina to the visual extrastriate and visuomotor systems. The majority of attention has been given to the role of this "visual" SC in saccade generation and target selection and it is generall...

journal_title：Journal of neurophysiology

authors： Girman SV,Lund RD

更新日期：2007-07-01 00:00:00

abstract：:We examined the activation kinetics of the delayed rectifier K+ current of bullfrog sympathetic neurons, primarily using whole cell recording. On depolarization, currents activated with a sigmoid delay but did not show a Cole-Moore shift. The time course of activation differed systematically from an exponential raised...

journal_title：Journal of neurophysiology

authors： Klemic KG,Durand DM,Jones SW

更新日期：1998-05-01 00:00:00

abstract：:Synapsin is a synaptic vesicle-associated protein implicated in the regulation of vesicle trafficking and transmitter release, but its role in heterosynaptic plasticity remains elusive. Moreover, contradictory results have obscured the contribution of synapsin to homosynaptic plasticity. We previously reported that th...

journal_title：Journal of neurophysiology

authors： Fioravante D,Liu RY,Netek AK,Cleary LJ,Byrne JH

更新日期：2007-12-01 00:00:00

abstract：:Directional hearing is crucial for animals depending on acoustic signals to locate a mate. We focused on crickets to explore the reliability of directional information forwarded to the brain by the ascending auditory interneuron AN1, which is crucial for phonotactic behavior. We presented calling song from -45° to +45...

journal_title：Journal of neurophysiology

authors： Lv M,Zhang X,Hedwig B

更新日期：2020-03-01 00:00:00

abstract：:We have examined the spatial integration properties of complex cells to determine whether some of their responses can be described by a maximum operation (MAX)-like computation, as suggested by Riesenhuber and Poggio's model of object recognition. Membrane potential was recorded from anesthetized cats while optimally ...

journal_title：Journal of neurophysiology

authors： Lampl I,Ferster D,Poggio T,Riesenhuber M

更新日期：2004-11-01 00:00:00