Subthreshold resonance explains the frequency-dependent integration of periodic as well as random stimuli in the entorhinal cortex.

abstract：:Gain-of-function variants in voltage-gated sodium channel NaV1.7 that increase firing frequency and spontaneous firing of dorsal root ganglion (DRG) neurons have recently been identified in 5-10% of patients with idiopathic small fiber neuropathy (I-SFN). Our previous in vitro observations suggest that enhanced sodium...

journal_title：Journal of neurophysiology

authors： Lee SI,Hoeijmakers JGJ,Faber CG,Merkies ISJ,Lauria G,Waxman SG

更新日期：2020-02-01 00:00:00

abstract：:While the effects of sensory feedback on bimanual tasks have been studied extensively at two ends of the motor control hierarchy, the cortical and behavioral levels, much less is known about how it affects the intermediate levels, including neural control of homologous muscle groups. We investigated the effects of som...

journal_title：Journal of neurophysiology

authors： Nguyen HB,Lee SW,Harris-Love ML,Lum PS

更新日期：2017-02-01 00:00:00

abstract：:We have previously reported that short-term (48-72 h) exposure to the GABA-modulatory steroid 3alpha-OH-5alpha-pregnan-20-one (3alpha,5alpha-THP) increases expression of the alpha4 subunit of the GABA(A) receptor (GABAR) in the hippocampus of adult rats. This change in subunit composition was accompanied by altered ph...

journal_title：Journal of neurophysiology

authors： Hsu FC,Waldeck R,Faber DS,Smith SS

更新日期：2003-04-01 00:00:00

abstract：:Synaptic drugs were superfused into turtle eyecup preparation while recording extracellularly from directionally sensitive (DS) retinal ganglion cells. As in previous experiments in intact rabbit retina, both picrotoxin (a GABA antagonist) and physostigmine [an acetylcholine (ACh) potentiator] reduced or eliminated th...

journal_title：Journal of neurophysiology

authors： Ariel M,Adolph AR

更新日期：1985-11-01 00:00:00

abstract：:The purpose of this study was to examine which primary afferent fibers are sensitized to mechanical stimuli after an experimental surgical incision to the glabrous skin of the rat hindpaw. Afferent fibers teased from the L(5) dorsal root or the tibial nerve were recorded in anesthetized rats. The mechanical response p...

journal_title：Journal of neurophysiology

authors： Hämäläinen MM,Gebhart GF,Brennan TJ

更新日期：2002-02-01 00:00:00

abstract：:Neurons in primary visual cortex are selective to the orientation and spatial frequency of sinusoidal gratings. In the classic model of cortical organization, a population of neurons responding to the same region of the visual field but tuned to all possible feature combinations provides a detailed representation of t...

journal_title：Journal of neurophysiology

authors： Jimenez LO,Tring E,Trachtenberg JT,Ringach DL

更新日期：2018-07-01 00:00:00

abstract：:Smooth pursuit eye movements are driven by retinal motion signals. These retinal motion signals are converted into motor commands that obey Listing's law (i.e., no accumulation of ocular torsion). The fact that smooth pursuit follows Listing's law is often taken as evidence that no explicit reference frame transformat...

journal_title：Journal of neurophysiology

authors： Blohm G,Lefèvre P

更新日期：2010-10-01 00:00:00

abstract：:Recently developed computational techniques have been used to reduce muscle activation patterns of high complexity to a simple synergy organization and to bring new insights to the long-standing degrees of freedom problem in motor control. We used a nonnegative factorization approach to identify muscle synergies durin...

journal_title：Journal of neurophysiology

authors： Ting LH,Macpherson JM

更新日期：2005-01-01 00:00:00

abstract：:How neurons filter and integrate their complex patterns of synaptic inputs is central to their role in neural information processing. Synaptic filtering and integration are shaped by the frequency-dependent neuronal membrane impedance. Using single and dual dendritic recordings in vivo, pharmacology, and computational...

journal_title：Journal of neurophysiology

authors： Dewell RB,Gabbiani F

更新日期：2019-08-01 00:00:00

abstract：:Subacute and chronic changes in tonic GABAergic inhibition occur in human and experimental epilepsy. Less is known about how tonic inhibition is modulated over shorter time frames (seconds). We measured endogenous tonic GABA currents from cultured rat hippocampal neurons to evaluate how they are affected by 1) transie...

journal_title：Journal of neurophysiology

authors： Ransom CB,Tao W,Wu Y,Spain WJ,Richerson GB

更新日期：2013-02-01 00:00:00

abstract：:1. Neuronal activity was recorded from the premotor cortex (PM) of Japanese monkeys while they performed hand movements with different amplitudes and directions. On each behavioral trial, two instructions were given sequentially: 1) an amplitude instruction (large or small) and 2) a direction instruction (flexion or e...

journal_title：Journal of neurophysiology

authors： Kurata K

更新日期：1993-01-01 00:00:00

abstract：:Training rats to perform rapidly and efficiently in an olfactory discrimination task results in robust enhancement of excitatory and inhibitory synaptic connectivity in the rat piriform cortex, which is maintained for days after training. To explore the mechanisms by which such synaptic enhancement occurs, we recorded...

journal_title：Journal of neurophysiology

authors： Saar D,Reuveni I,Barkai E

更新日期：2012-02-01 00:00:00

abstract：:Stability of images on the retina was determined in 14 normal humans in response to rotational and translational perturbations during self-generated pitch and yaw, standing, walking, and running on a treadmill. The effects on image stability of target distance, vision, and spectacle magnification were examined. During...

journal_title：Journal of neurophysiology

authors： Crane BT,Demer JL

更新日期：1997-10-01 00:00:00

abstract：:Inactivation permits direct assessment of the functional contribution of a given brain area to behavior. Previous inactivation studies of the frontal eye field (FEF) have either used large permanent ablations or reversible pharmacological techniques that only inactivate a small volume of tissue. Here we evaluated the ...

journal_title：Journal of neurophysiology

authors： Peel TR,Johnston K,Lomber SG,Corneil BD

更新日期：2014-01-01 00:00:00

abstract：:Many sensory brain regions are characterized by extensive local network interactions. However, we know relatively little about the contribution of this microcircuitry to sensory coding. Detailed analyses of neuronal microcircuitry are usually performed in vitro, whereas sensory processing is typically studied by recor...

journal_title：Journal of neurophysiology

authors： Ma X,Kohashi T,Carlson BA

更新日期：2013-07-01 00:00:00

abstract：:A large body of data suggests that the pontine respiratory group (PRG) is involved in respiratory phase-switching and the reconfiguration of the brain stem respiratory network. However, connectivity between the PRG and ventral respiratory column (VRC) in computational models has been largely ad hoc. We developed a net...

journal_title：Journal of neurophysiology

authors： Rybak IA,O'Connor R,Ross A,Shevtsova NA,Nuding SC,Segers LS,Shannon R,Dick TE,Dunin-Barkowski WL,Orem JM,Solomon IC,Morris KF,Lindsey BG

更新日期：2008-10-01 00:00:00

abstract：:Two forms of undulatory locomotion in the lamprey (a lower vertebrate) have been described earlier: fast forward swimming (FFS) used for long distance migrations and slow backward swimming (SBS) used for escape from adverse tactile stimuli. In the present study, we describe another form of escape behavior: slow forwar...

journal_title：Journal of neurophysiology

authors： Islam SS,Zelenin PV

更新日期：2008-01-01 00:00:00

abstract：:Mature stellate cells of the rat medial entorhinal cortex (EC), layer II, exhibit subthreshold membrane potential oscillations (MPOs) at theta frequencies (4-12 Hz) in vitro. We find that MPOs appear between postnatal days 14 (P14) and 18 (P18) but show little further change by day 28+ (P28-P32). To identify the facto...

journal_title：Journal of neurophysiology

authors： Burton BG,Economo MN,Lee GJ,White JA

更新日期：2008-12-01 00:00:00

abstract：:Human languages can express opposite propositions by means of the negative operator "not," which turns affirmative sentences into negative ones. Psycholinguistic research has indicated that negative meanings are formed by transiently reducing the access to mental representations of negated conceptual information. Neur...

journal_title：Journal of neurophysiology

authors： Bartoli E,Tettamanti A,Farronato P,Caporizzo A,Moro A,Gatti R,Perani D,Tettamanti M

更新日期：2013-04-01 00:00:00

abstract：:Ankle inversions have been studied extensively during standing conditions. However, inversion traumas occur during more dynamic conditions, like walking. Therefore in this study sudden ankle inversions were elicited in 12 healthy subjects who stepped on a trap door while walking on a treadmill. First, 10 control trial...

journal_title：Journal of neurophysiology

authors： Nieuwenhuijzen PH,Duysens J

更新日期：2007-10-01 00:00:00

abstract：:The characteristics of the primary afferent depolarization (PAD) of Ia- and Ib-fibers generated by segmental and descending inputs have been analyzed in the spinal cord of anesthetized cats. The PAD was inferred from the changes produced by conditioning inputs on the intraspinal stimulus current required to produce a ...

journal_title：Journal of neurophysiology

authors： Rudomin P,Solodkin M,Jiménez I

更新日期：1986-10-01 00:00:00

abstract：:1. Neuronal mechanisms for decoding sound azimuth and angular movement were studied by recordings of several single units in parallel in the core areas of the auditory cortex of the macaque monkey. The activity of 180 units was recorded during the presentation of moving and static sound stimuli. Both the activity of s...

journal_title：Journal of neurophysiology

authors： Ahissar M,Ahissar E,Bergman H,Vaadia E

更新日期：1992-01-01 00:00:00

abstract：:1. Presynaptic inhibition of synaptic transmission in the hippocampus was investigated by comparing the effects of several agonists on miniature excitatory and inhibitory postsynaptic currents (mEPSCs and mIPSCs). 2. The Ca2+ ionophore ionomycin increased the frequency of mEPSCs and mIPSCs but did not affect their amp...

journal_title：Journal of neurophysiology

authors： Capogna M,Gähwiler BH,Thompson SM

更新日期：1996-05-01 00:00:00

abstract：:The dorsal premotor area (PMd) of monkeys has been implicated in processes relating to movement preparation and movement selection. In the present study, we sought to determine whether PMd neurons that are activated during a delayed reaching task have directional responses that reflect either the target (i.e., the goa...

journal_title：Journal of neurophysiology

authors： Shen L,Alexander GE

更新日期：1997-03-01 00:00:00

abstract：:1. The alignment of the pupillary axes and of the visual axes has been measured in 23 normally reared cats ranging in age from 14 days to adulthood. 2. In agreement with a previous report, we find that pupillary divergence, as measured from photographs, tends to decrease during the first 2 mo of life. 3. The angle bet...

journal_title：Journal of neurophysiology

authors： Olson CR,Freeman RD

更新日期：1978-07-01 00:00:00

abstract：:The excitotoxic theory of Parkinson's disease (PD) hypothesizes that a pathophysiological degeneration of dopaminergic neurons stems from neural hyperactivity at early stages of disease, leading to mitochondrial stress and cell death. Recent research has harnessed the visual system of Drosophila PD models to probe thi...

journal_title：Journal of neurophysiology

authors： Himmelberg MM,West RJH,Elliott CJH,Wade AR

更新日期：2018-03-01 00:00:00

abstract：:1. Retzius (R) neurons of the fifth and sixth segmental ganglia of the leech, called R(5,6) neurons are specialized to innervate the adjacent reproductive organs and are morphologically and functionally distinct from R neurons of standard ganglia [R(x) cells]. In this study the electrical properties of the R(x) and R(...

journal_title：Journal of neurophysiology

authors： Merz DC

更新日期：1995-03-01 00:00:00

abstract：:Sensory inputs from muscle, cutaneous, and joint afferents project to the spinal cord, where they are able to affect ongoing locomotor activity. Activation of sensory input can initiate or prolong bouts of locomotor activity depending on the identity of the sensory afferent activated and the timing of the activation w...

journal_title：Journal of neurophysiology

authors： Bui TV,Brownstone RM

更新日期：2015-04-01 00:00:00

abstract：:Expression of the 5-HT(1Apl(a)) receptor in Aplysia pleural sensory neurons inhibited 5-HT-mediated translocation of the novel PKC Apl II in sensory neurons and prevented PKC-dependent synaptic facilitation at sensory to motoneuron synapses (Nagakura et al. 2010). We now demonstrate that the ability of inhibitory rece...

journal_title：Journal of neurophysiology

authors： Dunn TW,Farah CA,Sossin WS

更新日期：2012-01-01 00:00:00

abstract：:Parkinson's disease is associated with altered neural activity in the motor cortex. Chronic high-frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN) is effective in suppressing parkinsonian motor symptoms and modulates cortical activity. However, the anatomical pathways responsible for STN DBS-medi...

journal_title：Journal of neurophysiology

authors： Kumaravelu K,Oza CS,Behrend CE,Grill WM

更新日期：2018-08-01 00:00:00