Mammalian voltage-activated calcium channel currents are blocked by Pb2+, Zn2+, and Al3+.

abstract：:We show that fast bimanual coordinative feedback responses can be reversed with changes in task goals. Participants moved a flexible virtual object across a finish line with an upward movement of both hands. In one condition, the middle of the object had to be aligned with a spatial goal at the end of the movement. In...

journal_title：Journal of neurophysiology

authors： Diedrichsen J,Gush S

更新日期：2009-01-01 00:00:00

abstract：:1. The aim of this study was to examine the nature of motoneuron firing-rate modulation in type-identified motor units during smoothly graded contractions of the cat medial gastrocnemius (MG) muscle evoked by stimulation of the mesencephalic locomotor region (MLR). Motoneuron discharge patterns, firing rates, and the ...

journal_title：Journal of neurophysiology

authors： Tansey KE,Botterman BR

更新日期：1996-01-01 00:00:00

abstract：:The CNS controls reproduction through pulsatile secretion of gonadotropin-releasing hormone (GnRH). Episodic increases in the firing rate of unidentified hypothalamic neurons have been associated with downstream markers of GnRH secretion. Whether this episodic electrical activity is intrinsic to GnRH neurons, intrinsi...

journal_title：Journal of neurophysiology

authors： Nunemaker CS,DeFazio RA,Geusz ME,Herzog ED,Pitts GR,Moenter SM

更新日期：2001-07-01 00:00:00

abstract：:1. The simplicity of the jellyfish nervous system makes it an ideal preparation to assess the contributions of different ion channels to behavior. In the giant motor axons of the jellyfish Aglantha digitale, low-threshold spikes elicit slow swimming, whereas escape swimming depends on a higher-threshold, overshooting ...

journal_title：Journal of neurophysiology

authors： Meech RW,Mackie GO

更新日期：1993-03-01 00:00:00

abstract：:Regulation of feeding behavior involves the integration of multiple physiological and neurological pathways that control both nutrient-seeking and consummatory behaviors. The consummatory phase of ingestion includes stereotyped oromotor movements of the tongue and jaw that are controlled through brain stem pathways. T...

journal_title：Journal of neurophysiology

authors： Nasse JS,Travers JB

更新日期：2014-08-01 00:00:00

abstract：:Extracellular recordings were made from cold-receptive afferent fibers in the trigeminal ganglion of rats anesthetized with halothane. By applying a standardized series of steady or changing temperatures to the receptive fields, we recorded the static and dynamic responses of the afferents. Comparable recordings were ...

journal_title：Journal of neurophysiology

authors： Davies SN,Goldsmith GE,Hellon RF,Mitchell D

更新日期：1985-02-01 00:00:00

abstract：:Neural implants with large numbers of electrodes have become an important tool for examining brain functions. However, these devices typically displace a large intracranial volume compared with the neurons they record. This large size limits the density of implants, provokes tissue reactions that degrade chronic perfo...

journal_title：Journal of neurophysiology

authors： Egert D,Pettibone JR,Lemke S,Patel PR,Caldwell CM,Cai D,Ganguly K,Chestek CA,Berke JD

更新日期：2020-12-01 00:00:00

abstract：:Extracellular acidification induced by retinal horizontal cells has been hypothesized to underlie lateral feedback inhibition onto vertebrate photoreceptors. To test this hypothesis, the H(+)-sensitive fluorophore 5-hexadecanoylaminofluorescein (HAF) was used to measure changes in H(+) from horizontal cells isolated f...

journal_title：Journal of neurophysiology

authors： Jacoby J,Kreitzer MA,Alford S,Malchow RP

更新日期：2014-03-01 00:00:00

abstract：:In most of the bulbospinal respiratory neurons, threshold depolarization increased during the early period of their spontaneous burst discharge but decreased again at the end of a burst. In some vagal respiratory neurons, however, threshold depolarization increased steadily until the very end of their discharge period...

journal_title：Journal of neurophysiology

authors： Richter DW,Heyde F

更新日期：1975-09-01 00:00:00

abstract：:Current and voltage-clamp recordings were made at room temperature from cultured mouse spinal neurons using conventional two-electrode voltage-clamp techniques and electrodes filled with either 3 M KCl, 3 M CsCl, or 3 M Cs2SO4. In the presence of tetraethylammonium and tetrodotoxin, "fast" (rapidly rising and falling)...

journal_title：Journal of neurophysiology

authors： Owen DG,Segal M,Barker JL

更新日期：1986-06-01 00:00:00

abstract：:The parafacial respiratory group (pFRG), located in the lateral aspect of the rostroventral lateral medulla, has been described as a conditional expiratory oscillator that emerges mainly in conditions of high metabolic challenges to increase breathing. The convergence of inhibitory and excitatory inputs to pFRG and th...

journal_title：Journal of neurophysiology

authors： Silva JDN,Oliveira LM,Souza FC,Moreira TS,Takakura AC

更新日期：2020-05-01 00:00:00

abstract：:Functional magnetic resonance imaging blood-oxygenation-level-dependent (BOLD) signal increases (activations) and BOLD signal decreases ("deactivations") were compared in six healthy volunteers during galvanic vestibular (mastoid) and galvanic cutaneous (neck) stimulation in order to differentiate vestibular from ocul...

journal_title：Journal of neurophysiology

authors： Bense S,Stephan T,Yousry TA,Brandt T,Dieterich M

更新日期：2001-02-01 00:00:00

abstract：:Using intrinsic signal optical imaging (ISI), we have shown previously that the point spread of evoked activity in the rat barrel cortex in response to single-whisker stimulation encompasses a surprisingly large area. Given that our typical stimulation consists of five deflections at 5 Hz, the large area of evoked act...

journal_title：Journal of neurophysiology

authors： Polley DB,Chen-Bee CH,Frostig RD

更新日期：1999-02-01 00:00:00

abstract：:We have shown previously that in the acutely spinalized anesthetized rat the activities of many dorsal horn interneurons (DHN) at the T(10) level are correlated positively with both ongoing and stimulus-evoked renal sympathetic nerve activity (RSNA) and therefore may belong to networks generating RSNA after acute, cer...

journal_title：Journal of neurophysiology

authors： Chau D,Johns DG,Schramm LP

更新日期：2000-05-01 00:00:00

abstract：:Transcranial magnetic stimulation (TMS) is increasingly used to modify brain activity noninvasively and to study brain-behavior relations. However, results can be variable and the conditions that affect the functional efficacy of TMS remain unclear. Here we show that on-line TMS can either facilitate or suppress perce...

journal_title：Journal of neurophysiology

authors： Silvanto J,Cattaneo Z,Battelli L,Pascual-Leone A

更新日期：2008-05-01 00:00:00

abstract：:Nervous systems are thought to encode information as patterns of electrical activity distributed sparsely through networks of neurons. These networks then process information by transforming one pattern of electrical activity into another. To store information as a pattern, a neural network must strengthen synapses be...

journal_title：Journal of neurophysiology

authors： Jackson MB

更新日期：2013-12-01 00:00:00

abstract：:The role of dorsal root reflexes (DRRs) in acute cutaneous neurogenic inflammation induced by intradermal injection of capsaicin (CAP) was examined in anesthetized rats. Changes in cutaneous blood flow (flare) on the plantar surface of the foot were measured using a laser Doppler flowmeter, and neurogenic edema was ex...

journal_title：Journal of neurophysiology

authors： Lin Q,Wu J,Willis WD

更新日期：1999-11-01 00:00:00

abstract：:Rhythmic movements of the gastric mill and pyloric regions of the crustacean foregut are controlled by two stomatogastric neuronal networks that have been intensively studied in vitro. By using electromyographic recordings from the European lobster, Homarus gammarus, we have monitored simultaneously the motor activity...

journal_title：Journal of neurophysiology

authors： Clemens S,Combes D,Meyrand P,Simmers J

更新日期：1998-03-01 00:00:00

abstract：:The ventral nucleus of the lateral lemniscus (VNLL) is a major auditory nucleus that sends a large projection to the inferior colliculus. Despite its prominence, the responses of neurons in the VNLL have not been extensively studied. Previous studies in nonecholocating species have used anesthesia, which is known to a...

journal_title：Journal of neurophysiology

authors： Batra R,Fitzpatrick DC

更新日期：1999-09-01 00:00:00

abstract：:1. This study demonstrates plasticity of the vestibuloocular reflex (VOR) in chickens and compares it to that of other species and to that of newly hatched chicks. Adaptive changes in the VOR were induced by subjecting the animals to combinations of visual and vestibular stimuli that simulated the effect of the VOR be...

journal_title：Journal of neurophysiology

authors： Wallman J,Velez J,Weinstein B,Green AE

更新日期：1982-10-01 00:00:00

abstract：:Arrays of closely spaced quartz-insulated, platinum-tungsten microelectrodes are widely used to obtain acute recordings from chronically prepared subjects. These electrodes have excellent recording characteristics and can be fabricated to a wide variety of tip specifications. Typically, in such experiments, electrodes...

journal_title：Journal of neurophysiology

authors： Swadlow HA,Bereshpolova Y,Bezdudnaya T,Cano M,Stoelzel CR

更新日期：2005-05-01 00:00:00

abstract：:1. We have studied the responses of neurons in the lateral and descending vestibular nuclei of decerebrate cats to stimulation of neck receptors, produced by rotating the body in vertical planes with the head stationary. The responses to such neck stimulation were compared with the responses to vestibular stimulation ...

journal_title：Journal of neurophysiology

authors： Kasper J,Schor RH,Wilson VJ

更新日期：1988-11-01 00:00:00

abstract：:1. We reexamined the important areas of conflict in (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid [(1S,3R)-ACPD]-induced potentiation of the field excitatory postsynaptic potential (EPSP) and, for the first time, investigated the role of mGluRs in EPSP-spike (E-S) coupling. 2. (1S,3R)-ACPD (10 microM) bath applied...

journal_title：Journal of neurophysiology

authors： Breakwell NA,Rowan MJ,Anwyl R

更新日期：1996-11-01 00:00:00

abstract：:To examine the mechanisms underlying milk-ejection bursts of oxytocin (OT) neurons during suckling, both in vivo and in vitro studies were performed on supraoptic OT neurons from lactating rats. The bursts were first recorded extracellularly in anesthetized rats. Burst-related electrical parameters were essentially th...

journal_title：Journal of neurophysiology

authors： Wang YF,Hatton GI

更新日期：2004-05-01 00:00:00

abstract：:The goal of this study was to characterize the effects of corticotrophin-releasing factor (CRF) on rat paraventricular nucleus (PVN) putative parvocellular neurons using whole cell patch-clamp recordings and single-cell reverse transcription-multiplex polymerase chain reaction (single-cell RT-mPCR) techniques. Under c...

journal_title：Journal of neurophysiology

authors： Qiu DL,Chu CP,Shirasaka T,Tsukino H,Nakao H,Kato K,Kunitake T,Katoh T,Kannan H

更新日期：2005-07-01 00:00:00

abstract：:Proteinase-activated receptors (PARs) have a unique activation mechanism in that a proteolytically exposed N-terminal region acts as a tethered ligand. A potential impact of PAR on sensory processing has not been fully examined yet. Here we report that synthetic peptides with sequences corresponding to PAR ligands enh...

journal_title：Journal of neurophysiology

authors： Fujita T,Liu T,Nakatsuka T,Kumamoto E

更新日期：2009-07-01 00:00:00

abstract：:The human auditory system has an exceptional ability to separate competing sounds, but the neural mechanisms that underlie this ability are not understood. Responses of inferior colliculus (IC) neurons to "mistuned" complex tones were measured to investigate possible neural mechanisms for spectral segregation. A mistu...

journal_title：Journal of neurophysiology

authors： Sinex DG,Li H,Velenovsky DS

更新日期：2005-11-01 00:00:00

abstract：:The cholinergic system is critically involved in synaptic models of learning and memory by enhancing dendritic [Ca(2+)](i) signals. Diffuse cholinergic innervation suggests subcellular modulation of membrane currents and Ca(2+) signals. Here we use ion-selective microelectrodes to study spread of carbachol (CCh) after...

journal_title：Journal of neurophysiology

authors： Egorov AV,Gloveli T,Müller W

更新日期：1999-10-01 00:00:00

abstract：:The grip force applied to maintain grasp of a handheld object has been typically reported as tightly coupled to the load force exerted by the object as it is actively manipulated, occurring proportionally and consistently in phase with changes in load force. However, continuous grip force-load force coupling breaks do...

journal_title：Journal of neurophysiology

authors： Grover FM,Schwab SM,Silva PL,Lorenz T,Riley MA

更新日期：2019-12-01 00:00:00

abstract：:1. Bicuculline-induced epileptiform bursts in slices of neocortical tissue resected from children (3 mo to 14 yr) undergoing neurosurgical treatment for intractable epilepsy were studied with conventional intracellular recording techniques. The purposes of this study were to characterize the bursts evoked in immature ...

journal_title：Journal of neurophysiology

authors： Kim YI,Peacock WJ,Dudek FE

更新日期：1993-11-01 00:00:00