当前位置： SCI文献检索 > JOURNAL OF NEUROPHYSIOLOGY期刊下所有文献 > Discharge patterns of neurons in the ventral nucleus of the lateral lemniscus of the unanesthetized rabbit.

Discharge patterns of neurons in the ventral nucleus of the lateral lemniscus of the unanesthetized rabbit.

Abstract：

:The ventral nucleus of the lateral lemniscus (VNLL) is a major auditory nucleus that sends a large projection to the inferior colliculus. Despite its prominence, the responses of neurons in the VNLL have not been extensively studied. Previous studies in nonecholocating species have used anesthesia, which is known to affect discharge patterns. In addition, there is disagreement about the proportion of neurons that are sensitive to binaural stimulation. This report examines the responses of neurons in the VNLL of the unanesthetized rabbit to monaural and binaural stimuli. Most neurons responded to contralateral tone bursts at their best frequency and had either sustained or phasic discharge patterns. A few neurons were only inhibited. Most sustained neurons were classified as short-latency sustained (SL-sustained), but a few were of long latency. Some SL-sustained neurons exhibited multiple peaks in their discharge pattern, i.e., they had a "chopper" discharge pattern, whereas other SL-sustained neurons did not exhibit this pattern. In ordinary chopper neurons, the multiple peaks corresponded to the evenly spaced action potentials of a regular discharge. In unusual chopper neurons, the action potential associated with a particular peak could fail to occur during any one presentation of the stimulus. Unusual chopper neurons had a relatively irregular discharge. Phasic neurons were of two types: onset and transient. Onset neurons typically responded with a single action potential at the onset of the tone, whereas transient neurons produced a burst of action potentials. Transient neurons were relatively rare. About half the neurons also were influenced by ipsilateral stimulation. Most binaurally influenced neurons were either sensitive to interaural temporal disparities (ITDs) or excited by contralateral stimulation and inhibited by ipsilateral stimulation. Neurons sensitive to ITDs were mostly of the onset type and were embedded in the fiber tract medial to the main part of the nucleus. Neurons inhibited by ipsilateral stimulation could be of the sustained or onset type. The sustained neurons were located on the periphery of the main nucleus as well as in the fiber tract. Most of the monaural neurons were in the main, high-density part of VNLL. The present results demonstrate that the VNLL contains neurons with a heterogeneous set of responses, and that many of the neurons are binaural.

journal_name

J Neurophysiol

journal_title

Journal of neurophysiology

authors

Batra R,Fitzpatrick DC

doi

10.1152/jn.1999.82.3.1097

subject

Has Abstract

pub_date

1999-09-01 00:00:00

pages

1097-113

issue

eissn

0022-3077

issn

1522-1598

journal_volume

pub_type

杂志文章

在线工具

Discharge patterns of neurons in the ventral nucleus of the lateral lemniscus of the unanesthetized rabbit.