Increased sensitivity of sensory neurons to tumor necrosis factor alpha in rats with chronic compression of the lumbar ganglia.

abstract：:The creation of several prestin knockout and knockin mouse lines has demonstrated the importance of the intrinsic outer hair cell membrane protein prestin to mammalian hearing. However, the structure of prestin remains largely unknown, with even its major features in dispute. Several studies have suggested that presti...

journal_title：Journal of neurophysiology

authors： Currall B,Rossino D,Jensen-Smith H,Hallworth R

更新日期：2011-11-01 00:00:00

abstract：:The aim of this study was to determine the extent to which an attention-demanding visuomotor task affects the strength of the inhibitory control exerted by the wrist flexor group Ia afferents on the wrist extensor motoneurons. Effects of median nerve stimulation on the tonic activity of wrist extensor single motor uni...

journal_title：Journal of neurophysiology

authors： Nafati G,Schmied A,Rossi-Durand C

更新日期：2005-04-01 00:00:00

abstract：:Feedback and descending projections from higher to lower brain centers play a prominent role in all vertebrate sensory systems. Feedback might be optimized for the specific sensory processing tasks in their target brain centers, but it has been difficult to connect the properties of feedback synapses to sensory tasks....

journal_title：Journal of neurophysiology

authors： Harvey-Girard E,Maler L

更新日期：2013-12-01 00:00:00

abstract：:The majority of cerebral signals destined for the cerebellum are handed over by the pontine nuclei (PN), which thoroughly reorganize the neocortical topography. The PN maps neocortical signals of wide-spread origins into adjacent compartments delineated by spatially precise distribution of cortical terminals and posts...

journal_title：Journal of neurophysiology

authors： Möck M,Butovas S,Schwarz C

更新日期：2006-06-01 00:00:00

abstract：:Visual input provides vital information for helping us modify our walking pattern. For example, artificial optic flow can drive changes in step length during locomotion and may also be useful for augmenting locomotor training for individuals with gait asymmetries. Here we asked whether optic flow could modify the acqu...

journal_title：Journal of neurophysiology

authors： Finley JM,Statton MA,Bastian AJ

更新日期：2014-03-01 00:00:00

abstract：:1. The purpose of this study was to use the techniques of spike- and stimulus-triggered averaging (SpTA and StTA, respectively) to examine the output organization of individual rubromotoneuronal (RM) cells in relation to clusters of neighboring cells. SpTA of electromyographic (EMG) activity in awake monkeys reveals t...

journal_title：Journal of neurophysiology

authors： Cheney PD,Mewes K,Widener G

更新日期：1991-12-01 00:00:00

abstract：:Many rapidly firing neurons, including those in the medial nucleus of the trapezoid body (MNTB) in the auditory brain stem, express "high threshold" voltage-gated Kv3.1 potassium channels that activate only at positive potentials and are required for stimuli to generate rapid trains of actions potentials. We now descr...

journal_title：Journal of neurophysiology

authors： Brown MR,El-Hassar L,Zhang Y,Alvaro G,Large CH,Kaczmarek LK

更新日期：2016-07-01 00:00:00

abstract：:The generation of a behaviorally relevant cue to the speed of objects around us is critical to our ability to navigate safely within our environment. However, our perception of speed is often distorted by prevailing conditions. For instance, as luminance is reduced, our perception of the speed of fast-moving patterns ...

journal_title：Journal of neurophysiology

authors： Hammett ST,Smith AT,Wall MB,Larsson J

更新日期：2013-08-01 00:00:00

abstract：:Complex movements are generally thought to consist of a series of simpler elements. If this is so, how does the sensorimotor system assemble the pieces? This study recorded and evaluated sequences of arm movements to various targets placed in three-dimensional (3D) space. Subjects performed sequences consisting of sin...

journal_title：Journal of neurophysiology

authors： Klein Breteler MD,Hondzinski JM,Flanders M

更新日期：2003-06-01 00:00:00

abstract：:The rapid detection of sensory inputs is crucial for survival. Sensory detection explicitly requires the integration of incoming sensory information and the ability to distinguish between relevant information and ongoing neural activity. In this study, head-fixed rats were trained to detect the presence of a brief def...

journal_title：Journal of neurophysiology

authors： Ollerenshaw DR,Bari BA,Millard DC,Orr LE,Wang Q,Stanley GB

更新日期：2012-07-01 00:00:00

abstract：:Synaptic interactions between nearby excitatory and inhibitory neurons in the neocortex are thought to play fundamental roles in sensory processing. Here, we have combined optogenetic stimulation, whole cell recordings, and computational modeling to define key functional microcircuits within layer 2/3 of mouse primary...

journal_title：Journal of neurophysiology

authors： Avermann M,Tomm C,Mateo C,Gerstner W,Petersen CC

更新日期：2012-06-01 00:00:00

abstract：:We assessed synaptic α-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor (AMPAR) properties during synaptogenesis to describe the development of individual glutamatergic synapses on rat hippocampal CA1 principal neurons. Pharmacologically isolated AMPAR-mediated glutamatergic synaptic currents [evoked by stimul...

journal_title：Journal of neurophysiology

authors： Stubblefield EA,Benke TA

更新日期：2010-10-01 00:00:00

abstract：:1. The mismatch response, or mismatch negativity (MMN), is a neurophysiologic response to stimulus change. In humans and other animals, the MMN may underlie the ability to discriminate acoustic differences, a fundamental aspect of auditory perception. 2. This study investigated the role of the thalamus in the generati...

journal_title：Journal of neurophysiology

authors： Kraus N,McGee T,Littman T,Nicol T,King C

更新日期：1994-09-01 00:00:00

abstract：:Through their actions in the nucleus accumbens (NAc), kappa opioid (KOP) receptors and their endogenous ligand, dynorphin, modify behaviors associated with the administration of drugs of abuse and are regulated by exposure to such drugs. Despite their demonstrated behavioral significance, the synaptic actions of KOP r...

journal_title：Journal of neurophysiology

authors： Hjelmstad GO,Fields HL

更新日期：2003-05-01 00:00:00

abstract：:Olfactory receptor neurons (ORNs) respond to odorants with changes in the action potential firing rate. Excitatory responses, consisting of firing increases, are mediated by a cyclic AMP cascade that leads to the activation of cationic nonselective cyclic nucleotide-gated (CNG) channels and Ca2+-dependent Cl- (ClCa) c...

journal_title：Journal of neurophysiology

authors： Delgado R,Saavedra MV,Schmachtenberg O,Sierralta J,Bacigalupo J

更新日期：2003-09-01 00:00:00

abstract：:Mechanosensory neurons exhibit a wide range of dynamic changes in response, including rapid and slow adaptation. In addition to mechanical factors, electrical processes may also contribute to sensory adaptation. We have investigated adaptation of afferent neurons in the stick insect femoral chordotonal organ (fCO). Th...

journal_title：Journal of neurophysiology

authors： DiCaprio RA,Wolf H,Büschges A

更新日期：2002-11-01 00:00:00

abstract：:To investigate the dependence of velocity characteristics on spatiotemporal interactions the velocity selectivity of 15 geniculate and 72 cortical cells (areas 17 and 18) was examined with light and dark bars before and after masking all but the most sensitive part of the receptive field. The use of a 0.3 degree windo...

journal_title：Journal of neurophysiology

authors： Duysens J,Orban GA,Cremieux J

更新日期：1985-10-01 00:00:00

abstract：:The external anal sphincter (EAS) is important for the maintenance of bowel continence and may be compromised by a variety of neuropathic conditions. However, large animal models for the study of EAS functions have been sparse. The EAS guarding reflex was examined by electromyography (EMG) in neurologically intact rhe...

journal_title：Journal of neurophysiology

authors： Chang HH,Lee U,Vu T,Pikov V,Nieto JH,Christe KL,Havton LA

更新日期：2018-12-01 00:00:00

abstract：:Humans and animals value the opportunity to choose by preferring alternatives that offer more rather than fewer choices. This preference for choice may arise not only from an increased probability of obtaining preferred outcomes but also from the freedom it provides. We used human neuroimaging to investigate the neura...

journal_title：Journal of neurophysiology

authors： Fujiwara J,Usui N,Park SQ,Williams T,Iijima T,Taira M,Tsutsui K,Tobler PN

更新日期：2013-10-01 00:00:00

abstract：:1. The vestibuloocular reflex (VOR) undergoes long-term adaptive changes in the presence of persistent retinal image motion during head turns. Previous experiments using natural stimuli have provided evidence that the VOR is subserved by parallel pathways, including some that are modified during learning and some that...

journal_title：Journal of neurophysiology

authors： Broussard DM,Brontë-Stewart HM,Lisberger SG

更新日期：1992-06-01 00:00:00

abstract：:1. Intracellular recordings were made in 427 phrenic motoneurons from kittens (in four stages of postnatal development, ranging from 2 to 14 wk) and in 72 motoneurons from adult cats. These experiments were performed to determine how the pattern of spontaneous discharge changes in phrenic motoneurons during developmen...

journal_title：Journal of neurophysiology

authors： Cameron WE,Jodkowski JS,Fang H,Guthrie RD

更新日期：1991-03-01 00:00:00

abstract：:A total of 51 dorsal horn units responsive to heat were isolated and their receptive fields characterized (i.e., response properties and adequate stimuli determined) in pentobarbital-anesthetized, paralyzed rats. In 39 of the 51 units, the descending inhibition of heat-evoked activity produced by focal electrical stim...

journal_title：Journal of neurophysiology

authors： Jones SL,Gebhart GF

更新日期：1986-11-01 00:00:00

abstract：:Subacute and chronic changes in tonic GABAergic inhibition occur in human and experimental epilepsy. Less is known about how tonic inhibition is modulated over shorter time frames (seconds). We measured endogenous tonic GABA currents from cultured rat hippocampal neurons to evaluate how they are affected by 1) transie...

journal_title：Journal of neurophysiology

authors： Ransom CB,Tao W,Wu Y,Spain WJ,Richerson GB

更新日期：2013-02-01 00:00:00

abstract：:The voltage-gated K(+) channel Kv1.3 has been reported to regulate transmitter release in select central and peripheral neurons. In this study, we evaluated its role at the synapse between visceral sensory afferents and secondary neurons in the nucleus of the solitary tract (NTS). We identified mRNA and protein for Kv...

journal_title：Journal of neurophysiology

authors： Ramirez-Navarro A,Glazebrook PA,Kane-Sutton M,Padro C,Kline DD,Kunze DL

更新日期：2011-06-01 00:00:00

abstract：:1. Hindlimb paw-shake responses were assessed before and after unilateral deafferentation (L3-S1) in chronic-spinal cats (n = 5), spinalized at the T12 level 1 yr earlier. Selected ankle flexor [tibialis anterior (TA)] and extensor [lateral gastrocnemius (LG)] and knee extensor [vastus lateralis (VL)] muscles were sur...

journal_title：Journal of neurophysiology

authors： Koshland GF,Smith JL

更新日期：1989-07-01 00:00:00

abstract：:Previous analysis of the firing of individual rat hippocampal place cells has shown that their firing rate increases when they enter a place field and that their phase of firing relative to the ongoing theta oscillation (7-12 Hz) varies systematically as the rat traverses the place field, a phenomenon termed the theta...

journal_title：Journal of neurophysiology

authors： Jensen O,Lisman JE

更新日期：2000-05-01 00:00:00

abstract：:Several previous studies have shown the existence of Up and Down states and have linked their magnitude (e.g., depolarization level) to the size of sensory-evoked responses. Here, we studied how the temporal dynamics of such states influence the sensory-evoked response to vibrissa deflection. Under alpha-chloralose an...

journal_title：Journal of neurophysiology

authors： Haslinger R,Ulbert I,Moore CI,Brown EN,Devor A

更新日期：2006-09-01 00:00:00

abstract：:1. A characteristic plateau pattern was observed in the rate of afferent discharges during ramp-and-hold stretch of spindles isolated from semitendinosus muscles of frogs. The plateau pattern was more frequent in summer frogs (84%) than winter frogs (11%). 2. The plateau pattern consisted of a discharge rate around 12...

journal_title：Journal of neurophysiology

authors： Sokabe M,Nunogaki K,Naruse K,Soga H,Fujitsuka N,Yoshimura A,Ito F

更新日期：1993-07-01 00:00:00

abstract：:Overestimation of roll tilt in hypergravity ("G-excess" illusion) has been demonstrated, but corresponding sustained hypogravic conditions are impossible to create in ground laboratories. In this article we describe the first systematic experimental evidence that in a hypogravity analog, humans underestimate roll tilt...

journal_title：Journal of neurophysiology

authors： Galvan-Garza RC,Clark TK,Sherwood D,Diaz-Artiles A,Rosenberg M,Natapoff A,Karmali F,Oman CM,Young LR

更新日期：2018-12-01 00:00:00

abstract：:The complementary DNA encoding gustatory cyclic nucleotide--gated ion channel (or gustCNG channel) cloned from rat tongue epithelial tissue was expressed in Xenopus oocytes, and its electrophysiological characteristics were investigated using tight-seal patch-clamp recordings of single and macroscopic channel currents...

journal_title：Journal of neurophysiology

authors： Lee HM,Park YS,Kim W,Park CS

更新日期：2001-06-01 00:00:00