Functional unity of the ponto-cerebellum: evidence that intrapontine communication is mediated by a reciprocal loop with the cerebellar nuclei.

abstract：:cAMP-dependent protein kinase (PKA) and protein kinase C (PKC) are two major modulators of synaptic transmission in the CNS but little is known about how they affect synaptic transmission in the human CNS. In this study, we used forskolin, a PKA activator, and phorbol ester, a PKC activator, to examine the effects of ...

journal_title：Journal of neurophysiology

authors： Chen HX,Roper SN

更新日期：2003-05-01 00:00:00

abstract：:Fear conditioning studies have led to the view that the amygdala contains neurons that signal threat and in turn elicit defensive behaviors through their brain stem and hypothalamic targets. In agreement with this model, a prior unit-recording study in rats performing a seminaturalistic foraging task revealed that man...

journal_title：Journal of neurophysiology

authors： Amir A,Kyriazi P,Lee SC,Headley DB,Paré D

更新日期：2019-05-01 00:00:00

abstract：:Nervous systems are thought to encode information as patterns of electrical activity distributed sparsely through networks of neurons. These networks then process information by transforming one pattern of electrical activity into another. To store information as a pattern, a neural network must strengthen synapses be...

journal_title：Journal of neurophysiology

authors： Jackson MB

更新日期：2013-12-01 00:00:00

abstract：:1. B31 and B32 are pattern-initiator neurons in the buccal ganglia of Aplysia. Along with the B61/B62 neurons, B31/B32 are also motor neurons that innervate the 12 buccal muscle via the I2 nerve. This research was aimed at determining the physiological functions of the B31/B32 and B61/B62 neurons, and of the I2 muscle...

journal_title：Journal of neurophysiology

authors： Hurwitz I,Neustadter D,Morton DW,Chiel HJ,Susswein AJ

更新日期：1996-04-01 00:00:00

abstract：:1. Current- and voltage-clamp studies were conducted on isolated rat adrenal chromaffin cells to identify the voltage-dependent ion channels mediating inward currents. 2. Mean resting membrane potential of the isolated cells was -62 +/- 3 (SE) mV. Evoked action potentials were both Na+ and Ca2+ based, and whole cell v...

journal_title：Journal of neurophysiology

authors： Hollins B,Ikeda SR

更新日期：1996-08-01 00:00:00

abstract：:1. The physiological and pharmacological properties of excitatory amino acid (EAA)-induced responses were investigated in acutely isolated spiral ganglion cells of guinea pig by a conventional patch-clamp technique combined with a rapid drug application (Y-tube) method. 2. L-glutamate (Glu) and its agonists, quisquala...

journal_title：Journal of neurophysiology

authors： Nakagawa T,Komune S,Uemura T,Akaike N

更新日期：1991-03-01 00:00:00

abstract：:Across the rostrocaudal (RC) axis of the Xenopus tadpole optic tectum exists a developmental gradient. This gradient has served as a useful model to study many aspects of synapse and dendrite maturation. To compliment these studies, we characterized how the intrinsic excitability, the ease in which a neuron can fire a...

journal_title：Journal of neurophysiology

authors： Hamodi AS,Pratt KG

更新日期：2014-10-01 00:00:00

abstract：:1. Hindlimb paw-shake responses were assessed before and after unilateral deafferentation (L3-S1) in chronic-spinal cats (n = 5), spinalized at the T12 level 1 yr earlier. Selected ankle flexor [tibialis anterior (TA)] and extensor [lateral gastrocnemius (LG)] and knee extensor [vastus lateralis (VL)] muscles were sur...

journal_title：Journal of neurophysiology

authors： Koshland GF,Smith JL

更新日期：1989-07-01 00:00:00

abstract：:Event-related potentials (ERPs) have provided crucial data concerning the time course of psychological processes, but the neural mechanisms producing ERP components remain poorly understood. This study continues a program of research in which we investigated the neural basis of attention-related ERP components by simu...

journal_title：Journal of neurophysiology

authors： Purcell BA,Schall JD,Woodman GF

更新日期：2013-01-01 00:00:00

abstract：:The purpose of our study was to examine the associations between the performance of older adults on four tests of mobility and the physical capabilities of the lower leg muscles. The assessments included measures of muscle strength, muscle activation, and perceived fatigability. Muscle activation was quantified as the...

journal_title：Journal of neurophysiology

authors： Mani D,Almuklass AM,Hamilton LD,Vieira TM,Botter A,Enoka RM

更新日期：2018-10-01 00:00:00

abstract：:Cortical activity contributes significantly to the high variability of sensory responses of interconnected pyramidal neurons, which has crucial implications for sensory coding. Yet, largely because of technical limitations of in vivo intracellular recordings, the coupling of a pyramidal neuron's synaptic inputs to the...

journal_title：Journal of neurophysiology

authors： Wright NC,Hoseini MS,Yasar TB,Wessel R

更新日期：2017-12-01 00:00:00

abstract：:1. It has been suggested that passive diffusion is the principal mechanism of the clearance of locally elevated extracellular potassium, K+o, in the cerebral cortex. This concept was based on the assumption that elevated K+ could be modeled as a point source. In the present study, the functional role of passive diffus...

journal_title：Journal of neurophysiology

authors： Vern BA,Schuette WH,Thibault LE

更新日期：1977-09-01 00:00:00

abstract：:Detection and discrimination of odors generally, if not always, occurs against an odorous background. On any given inhalation, olfactory receptor neurons will be activated by features of both the target odorant and features of background stimuli. To identify a target odorant against a background therefore, the olfacto...

journal_title：Journal of neurophysiology

authors： Kadohisa M,Wilson DA

更新日期：2006-03-01 00:00:00

abstract：:A description of healthy and pathological brain dynamics requires an understanding of spatiotemporal patterns of neural activity and characteristics of its propagation between interconnected circuits. However, the structure and modulation of the neural activation maps underlying these patterns and their propagation re...

journal_title：Journal of neurophysiology

authors： Hazra A,Rosenbaum R,Bodmann B,Cao S,Josić K,Žiburkus J

更新日期：2012-07-01 00:00:00

abstract：:We investigated the postnatal development of axon sensitivity to the withdrawal of oxygen, glucose, or the combined withdrawal of oxygen + glucose in the isolated rat optic nerve (a CNS white matter tract). Removal of either oxygen or glucose for 60 min resulted in irreversible injury in optic nerves from adult rats, ...

journal_title：Journal of neurophysiology

authors： Fern R,Davis P,Waxman SG,Ransom BR

更新日期：1998-01-01 00:00:00

abstract：:The holoplanktonic pteropod mollusk Clione limacina exhibits an active escape behavior that is characterized by fast swimming away from the source of potentially harmful stimuli. The initial phase of escape behavior is a startle response that is controlled by pedal motoneurons whose activity is independent of the norm...

journal_title：Journal of neurophysiology

authors： Norekian TP,Satterlie RA

更新日期：1997-01-01 00:00:00

abstract：:The superior colliculus (SC) provides signals for the generation of saccades via a direct pathway to the brain stem burst generator (BG). In addition, it sends saccade-related activity to the BG indirectly through the cerebellum via a relay in the nucleus reticularis tegmenti pontis (NRTP). Lesions of the oculomotor v...

journal_title：Journal of neurophysiology

authors： Kaneko CR,Fuchs AF

更新日期：2006-06-01 00:00:00

abstract：:Alphabetagamma GABA(A) receptor currents are phasic and desensitizing, whereas alphabetadelta GABA(A) receptor currents are tonic and have no fast desensitization. alphabetagamma receptors are subsynaptic and mediate phasic inhibition, whereas alphabetadelta receptors are extra- or perisynaptic and mediate tonic inhib...

journal_title：Journal of neurophysiology

authors： Feng HJ,Macdonald RL

更新日期：2004-09-01 00:00:00

abstract：:Histamine is a known secretagogue in adrenal chromaffin cells. Activation of G-protein linked H(1) receptors stimulates phospholipase C, which generates inositol trisphosphate leading to release of intracellular calcium stores and stimulation of calcium influx through store operated and other channels. This calcium le...

journal_title：Journal of neurophysiology

authors： Currie KP,Fox AP

更新日期：2000-03-01 00:00:00

abstract：:Normative theories posit that value-based decision-making is context independent. However, decisions between two high-value options can be suboptimally biased by the introduction of a third low-value option. This context-dependent modulation is consistent with the divisive normalization of the value of each stimulus b...

journal_title：Journal of neurophysiology

authors： Itthipuripat S,Cha K,Rangsipat N,Serences JT

更新日期：2015-07-01 00:00:00

abstract：:To characterize spike coding in spinal neurons during rhythmic locomotor activity, we recorded from individual cells in the lumbar spinal cord of neonatal rats by using the on-cell patch-clamp technique. Locomotor activity was induced by N-methyl-D aspartate (NMDA) and 5-hydroxytryptamine (5-HT) and monitored by ventr...

journal_title：Journal of neurophysiology

authors： Raastad M,Kiehn O

更新日期：2000-05-01 00:00:00

abstract：:The effect of peripheral lesions on cerebral somatosensory representations is well studied for experimentally induced amputations and deafferentations acquired later in life. However, few studies have investigated the brain's capacity for plastic changes in congenital malformations. We studied somatosensory-evoked fie...

journal_title：Journal of neurophysiology

authors： Stoeckel MC,Pollok B,Witte OW,Seitz RJ,Schnitzler A

更新日期：2005-02-01 00:00:00

abstract：:The functional role of sensory input to the motor cortex was studied by interrupting two major input pathways. One was the dorsal column, which sends the input directly through the thalamus to the motor cortex, and the other was the sensory cortex, which transfers its input through association fibers. Removal of the s...

journal_title：Journal of neurophysiology

authors： Asanuma H,Arissian K

更新日期：1984-08-01 00:00:00

abstract：:1. Behavioral studies in the monkey and clinical studies in humans show that some visuomotor functions are spared in case of a V1 lesion. This residual vision appears to be subserved at least partially by visual activity in extrastriate cortex. Earlier studies have demonstrated that neurons in area V2 lose their visua...

journal_title：Journal of neurophysiology

authors： Girard P,Salin PA,Bullier J

更新日期：1991-11-01 00:00:00

abstract：:This study reexamined the perceptual equivalence of active and passive touch using a computer-controlled force-feedback device. Nine subjects explored a 6 x 10-cm workspace, with the index finger resting on a mobile flat plate, and experienced simulated Gaussian ridges and troughs (width, 15 mm; amplitude, 0.5 to 4.5 ...

journal_title：Journal of neurophysiology

authors： Smith AM,Chapman CE,Donati F,Fortier-Poisson P,Hayward V

更新日期：2009-12-01 00:00:00

abstract：:The cholinergic system is critically involved in synaptic models of learning and memory by enhancing dendritic [Ca(2+)](i) signals. Diffuse cholinergic innervation suggests subcellular modulation of membrane currents and Ca(2+) signals. Here we use ion-selective microelectrodes to study spread of carbachol (CCh) after...

journal_title：Journal of neurophysiology

authors： Egorov AV,Gloveli T,Müller W

更新日期：1999-10-01 00:00:00

abstract：:1. One hundred seventy-nine single units were studied in the superior colliculus of seven Dutch-belted rabbits following ablation of the ipsilateral visual cortex. The response characteristics of these units were compared with those of 284 single units recorded from the superior colliculus of 20 intact animals. 2. In ...

journal_title：Journal of neurophysiology

authors： Graham J,Berman N,Murphy EH

更新日期：1982-02-01 00:00:00

abstract：:Without intervention after spinal cord injury (SCI), paralyzed skeletal muscles undergo myofiber atrophy and slow-to-fast myofiber type transformations. We hypothesized that chronic spasticity-associated neuromuscular activity after SCI would promote recovery from such deleterious changes. We examined segmental tail m...

journal_title：Journal of neurophysiology

authors： Harris RL,Putman CT,Rank M,Sanelli L,Bennett DJ

更新日期：2007-02-01 00:00:00

abstract：:1. A variety of pharmacological tests indicate that the neuromuscular junction between the salivary burster neuron (SB) and the salivary duct muscle (SD) in the terrestrial mollusk Limax maximus is cholinergic. These include the effects of curare, atropine, and hexamethonium. 2. Exogenously applied choline can act bot...

journal_title：Journal of neurophysiology

authors： Barry SR,Gelperin A

更新日期：1982-08-01 00:00:00

abstract：:1. Neuronal activity was recorded from the premotor cortex (PM) of Japanese monkeys while they performed hand movements with different amplitudes and directions. On each behavioral trial, two instructions were given sequentially: 1) an amplitude instruction (large or small) and 2) a direction instruction (flexion or e...

journal_title：Journal of neurophysiology

authors： Kurata K

更新日期：1993-01-01 00:00:00