Abstract:
:1. The onset of visual activity in the superficial layers of the cat superior colliculus begins abruptly at about 6 days postnatal (DPN), just before natural eye opening. Despite the presence of many inactive sites at this time, the systematic nature of the superior colliculus visuotopy is already evident. The number of inactive sites across the horizontal dimension of the superficial layers decreases rapidly so that by 9-10 DPN most sites are visually responsive. 2. Initially, visual activity is restricted to the topmost portion of the superficial gray layer, where W-cell terminals predominate, but rapidly extends down to include Y-cell territory at 10 DPN. 3. In contrast to what might have been expected based on earlier behavioral observations, there was no physiological evidence for a central-to-peripheral gradient in the development of the superior colliculus visuotopy. Rather, the entire visual field is well represented long before the expression of any visually initiated behaviors. 4. In contrast to the rapidity of the appearance and organization of the visual representation in superficial layers, deep layers remain refractory to visual stimuli for weeks.
journal_name
J Neurophysioljournal_title
Journal of neurophysiologyauthors
Kao CQ,McHaffie JG,Meredith MA,Stein BEdoi
10.1152/jn.1994.72.1.266subject
Has Abstractpub_date
1994-07-01 00:00:00pages
266-72issue
1eissn
0022-3077issn
1522-1598journal_volume
72pub_type
杂志文章abstract::1. The synthesis of information from different sensory modalities in the superior colliculus is an important precursor of attentive and orientation behavior. 2. This integration of multisensory information is critically dependent on inputs from a small area of association cortex, the anterior ectosylvian sulcus. Remov...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1994.71.1.429
更新日期:1994-01-01 00:00:00
abstract::Traditional electrophysiological research on invertebrate photoreceptors has been conducted in vivo, using intracellular recordings from intact compound eyes. The only exception used to be Drosophila melanogaster, which was exhaustively studied by both intracellular recording and patch-clamp methods. Recently, several...
journal_title:Journal of neurophysiology
pub_type: 杂志文章,评审
doi:10.1152/jn.00288.2016
更新日期:2016-08-01 00:00:00
abstract::Robust auditory perception plays a pivotal function for processing behaviorally relevant sounds, particularly with distractions from the environment. The neuronal coding enabling this ability, however, is still not well understood. In this study, we recorded single-unit activity from the primary auditory cortex (A1) o...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00476.2016
更新日期:2017-02-01 00:00:00
abstract::A consistent feature of animal locomotion is the capacity to maintain stable movements in changing environments. Here we describe long-term modification of the swing movement of the hind leg in cats in response to repeatedly impeding the movement of the leg. While studying phase transitions in the hind legs, we discov...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00921.2006
更新日期:2007-01-01 00:00:00
abstract::1. Intracellular recordings were made from layer VI pyramidal cells in in vitro slice preparations of the cat motor cortex (area 4 gamma). Layer VI pyramidal cells were identified morphologically by intracellular injection of biocytin. 2. Of 22 layer VI pyramidal cells examined, single action potentials were followed ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1994.72.2.578
更新日期:1994-08-01 00:00:00
abstract::Attention is known to affect the response properties of sensory neurons in visual cortex. These effects have been traditionally classified into two categories: 1) changes in the gain (overall amplitude) of the response; and 2) changes in the tuning (selectivity) of the response. We performed an extensive series of beh...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00776.2011
更新日期:2012-03-01 00:00:00
abstract::1. The discharge of individual neurons in the visual cortex and lateral geniculate nucleus (LGN) of anesthetized and paralyzed cats and kittens was examined for the presence of oscillatory activity. Neural firing was evoked through the monoptic or dichoptic presentation of drifting gratings and random sequences of fla...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1992.68.5.1558
更新日期:1992-11-01 00:00:00
abstract::Efficient sensory coding implies that populations of neurons should represent information-rich aspects of a signal with little redundancy. Recent studies have shown that neural heterogeneity in higher brain areas enhances the efficiency of encoding by reducing redundancy across the population. Here, we study how neura...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00256.2010
更新日期:2010-11-01 00:00:00
abstract::Previous studies have reported an important relationship between increasing age, vestibular impairment, and increased risk of falls. Recently, noisy galvanic vestibular stimulation (nGVS) has been shown to improve postural control in older adults during and potentially following stimulation. However, this effect of nG...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00512.2020
更新日期:2020-12-09 00:00:00
abstract::Granule cells and parallel fiber circuits in the dorsal cochlear nucleus (DCN) play a role in integration of multimodal sensory with auditory inputs. The activity of granule cells is regulated through inhibitory connections made by Golgi cells. Golgi cells in turn probably receive parallel fiber inputs and regulate ac...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00396.2006
更新日期:2006-11-01 00:00:00
abstract::1. Both stretch and release of the ventral superficial muscles (VSM) in the abdomen of the hermit crab, Pagurus pollicarus, activate the VSM motoneurons in the intact animal and in the isolated abdomen. 2. This reflex was studied by recording intracellularly from muscle fibers innervated by single motoneurons during s...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1993.69.6.1904
更新日期:1993-06-01 00:00:00
abstract::An imbalance between the strengths of excitatory and inhibitory synaptic inputs has been proposed as the cellular basis of autism and related neurodevelopmental disorders. Previous studies examining spontaneous levels of excitatory and inhibitory neurotransmission in the forebrain regions of methyl-CpG-binding protein...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00751.2010
更新日期:2011-07-01 00:00:00
abstract::Gain-of-function missense mutations in voltage-gated sodium channel Nav1.7 have been linked to small-fiber neuropathy, which is characterized by burning pain, dysautonomia and a loss of intraepidermal nerve fibers. However, the mechanistic cascades linking Nav1.7 mutations to axonal degeneration are incompletely under...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00195.2015
更新日期:2015-09-01 00:00:00
abstract::Smooth pursuit eye movements are driven by retinal motion signals. These retinal motion signals are converted into motor commands that obey Listing's law (i.e., no accumulation of ocular torsion). The fact that smooth pursuit follows Listing's law is often taken as evidence that no explicit reference frame transformat...
journal_title:Journal of neurophysiology
pub_type: 杂志文章,随机对照试验
doi:10.1152/jn.00728.2009
更新日期:2010-10-01 00:00:00
abstract::1. The role of the microgeometry of planar surfaces in the detection of sliding of the surfaces on human and monkey fingerpads was investigated. By the use of a servo-controlled tactile stimulator to press and stroke glass plates on passive fingerpads of human subjects, the ability of humans to discriminate the direct...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1990.63.6.1323
更新日期:1990-06-01 00:00:00
abstract::We describe a novel chamber in which the two intact neonatal rat hippocampi and the commissural fibers are placed in three independent compartments separated by latex membranes and perfused selectively with different solutions. A set of control tests showed that the compartments are well isolated: 1) methylene blue or...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1999.81.2.921
更新日期:1999-02-01 00:00:00
abstract::Generalizing newly learned movement patterns beyond the training context is challenging for most motor learning situations. Here we tested whether learning of a new physical property of the arm during self-initiated reaching generalizes to new arm configurations. Human participants performed a single-joint elbow reach...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00696.2019
更新日期:2020-03-01 00:00:00
abstract::Annexin I is a local mediator in neural-endocrine feedback control of inflammation. J. Neurophysiol. 80: 3120-3126, 1998. Activation of primary afferent nociceptors induces a neural endocrine-mediated inhibition of the inflammatory response via a circuit that includes ascending spinal pathways and activation of the hy...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1998.80.6.3120
更新日期:1998-12-01 00:00:00
abstract::We asked whether podokinetic adaptation to walking on a circular treadmill transfers to different forms of locomotion. Subjects were blindfolded and asked to walk straight across the floor, in the forward and backward directions, following podokinetic (PK) stimulation that consisted of 30 min of forward walking-in-pla...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.2001.86.4.1666
更新日期:2001-10-01 00:00:00
abstract::Neuropeptide Y (NPY) potently inhibits glutamate-mediated synaptic transmission in areas CA1 and CA3 of the rat hippocampus without affecting other synaptic inputs onto principal cells of the hippocampal formation, suggesting that its biological role may include the regulation of excitability within the hippocampus. H...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1997.78.3.1651
更新日期:1997-09-01 00:00:00
abstract::1. Many examples of long-term potentiation (LPT) are induced by repetitive electrical stimulation of presynaptic axons. LTP also is induced by direct glutamate iontophoresis (1 M, 1-2 microA, 10 s) onto postsynaptic neurons in hippocampal slices without evoked presynaptic stimulation; this form of LTP is called "ionto...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1996.75.5.1909
更新日期:1996-05-01 00:00:00
abstract::1. Study of memory traces in higher animals requires experimental models possessing well-localized and technically accessible memory traces--plasticity responsible for behavioral change, not dependent on control from elsewhere, and open to detailed investigation. Our purpose has been to develop such a model based on t...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1989.61.3.563
更新日期:1989-03-01 00:00:00
abstract::1. The electrical responses of nociceptive (N) lateral and N medial neurons of the leech segmental ganglion to mechanical, chemical, and thermal stimulation of the skin were studied in a superfused ganglion-body wall preparation. 2. Mechanical indentation of the skin > 10 mN evoked in both types of cells a sustained d...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1996.75.6.2268
更新日期:1996-06-01 00:00:00
abstract::Synchronization between the firing times of simultaneously active motor units (MUs) is generally assumed to increase during fatiguing contractions. To date, however, estimates of MU synchronization have relied on indirect measures, derived from surface electromyographic (EMG) interference signals. This study used intr...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00097.2016
更新日期:2016-06-01 00:00:00
abstract::Properties of calcium spikes revealed during GABAA receptor antagonism in hippocampal CA1 neurons from guinea pigs. J. Neurophysiol. 78: 2269-2279, 1997. Intracellular electrical responses and changes in intracellular calcium concentration ([Ca2+]i) in response to activation of synaptic inputs and to DC injections wer...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1997.78.5.2269
更新日期:1997-11-01 00:00:00
abstract::1. To characterize the temporal dynamic responses of ganglion cells and to define the possible inputs giving rise to their responses in catfish retina, we recorded the ganglion cell responses evoked by 1) a step of light presented in the dark, 2) an incremental and decremental step from a background illumination, and ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1987.58.6.1307
更新日期:1987-12-01 00:00:00
abstract::1. Spontaneous synaptic activity in networks formed by dissociated neurons from embryonic rat midbrain was analyzed in tight seal whole cell recordings. 2. Application of furosemide (0.5 mM) to the cell and its surrounding area increased the frequency of spontaneous synaptic currents. Incubation of the culture with fu...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1996.75.6.2654
更新日期:1996-06-01 00:00:00
abstract::1. Neuron-specific expression of alternately spliced exons of the gene encoding the Phe-Met-Arg-Phe-NH2 (FMRFamide) family of neuropeptides and the role of encoded peptides in synaptic transmission were examined in an identified cardiorespiratory interneuron, the visceral white interneuron (VWI), in the snail Lymnaea....
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1993.69.3.915
更新日期:1993-03-01 00:00:00
abstract::While the effects of sensory feedback on bimanual tasks have been studied extensively at two ends of the motor control hierarchy, the cortical and behavioral levels, much less is known about how it affects the intermediate levels, including neural control of homologous muscle groups. We investigated the effects of som...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00269.2016
更新日期:2017-02-01 00:00:00
abstract::Prominent arginine-vasopressin (AVP) binding and AVP V(1) type receptors are expressed early in the developing rat spinal cord. We sought to characterize their influence on neural excitability by using patch-clamp techniques to record AVP-induced responses from a population of motoneurons and interneurons in neonatal ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.2001.86.3.1202
更新日期:2001-09-01 00:00:00